Outpatient management of inflammatory bowel disease. Let's keep it as simple as possible.

Abstract:

:Inflammatory bowel disease is a conglomeration of disorders of unclear etiology and pathogenesis. Confirming the diagnosis of active disease may be difficult but is critical to judicious therapy. Sulfasalazine (Azulfidine) and its newer derivatives mesalamine (Asacol, Rowasa) and olsalazine sodium (Dipentum) are used for treatment of mild disease and maintenance. Corticosteroid therapy controls moderate disease in most patients, but withdrawal may be difficult. Immunosuppression or surgery may be necessary in severe or refractory cases. The risk of cancer as a complication of inflammatory bowel disease is often exaggerated but cannot be ignored.

journal_name

Postgrad Med

journal_title

Postgraduate medicine

authors

Butt JH

doi

10.1080/00325481.1992.11701512

subject

Has Abstract

pub_date

1992-11-01 00:00:00

pages

69-72, 77-8, 81-4, 91-2, 94 passim

issue

6

eissn

0032-5481

issn

1941-9260

journal_volume

92

pub_type

杂志文章,评审
  • Thymoma. The most common anterior mediastinal mass.

    abstract::Thymomas may be discovered during routine evaluation, through reported symptoms, or increasingly, during evaluation for myasthenia gravis. Histologic details of these tumors have little bearing on prognosis or evaluation of malignant potential. Malignancy is determined by evidence of invasion through the tumor capsule...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1986.11699321

    authors: Cohen DJ

    更新日期:1986-03-01 00:00:00

  • Emergent signs of cancer. Recognizing them early in the office or ER.

    abstract::Primary care physicians have a crucial role in recognition of potentially emergent conditions in patients with known or suspected cancer. This task presents a significant challenge because the initial manifestations of these conditions are usually nonspecific. In most cases, therapy is far more effective when diagnosi...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1990.11704773

    authors: Love N

    更新日期:1990-12-01 00:00:00

  • Migraine headache. Working for the best outcome.

    abstract::Migraine is a common hereditary disorder manifested by episodic headache, irritability, and gastrointestinal upset. The condition may be triggered by dietary, environmental, psychological, or pharmacologic factors. With proper diagnosis and judicious use of abortive and prophylactic therapy, patients often obtain exce...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1987.11699870

    authors: Diamond S,Freitag FG,Solomon GD,Millstein E

    更新日期:1987-06-01 00:00:00

  • The role of topical 5% acyclovir and 1% hydrocortisone cream (Xerese™) in the treatment of recurrent herpes simplex labialis.

    abstract::Recurrent herpes simplex labialis (HSL), also known as orofacial herpes or cold sores, is a common clinical presentation of herpes simplex virus (HSV) infection. It may manifest as painful, distressing, and cosmetically displeasing vesicles on the lips, nose, and nasal septum. Although oral or topical treatment with a...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.3810/pgm.2010.09.2216

    authors: Hull CM,Brunton S

    更新日期:2010-09-01 00:00:00

  • Reducing cardiovascular risk: trends in risk, risk assessment, and cholesterol management.

    abstract::The rate of decrease in coronary heart disease (CHD) mortality in the United States has slowed, probably in association with the aging of the population and the increasing rates of obesity, metabolic syndrome, and diabetes. Worldwide, guidelines for reducing risk of CHD and lowering lipid levels must continue to evolv...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.3810/pgm.09.2004.suppl34.206

    authors: Davidson MH

    更新日期:2004-09-01 00:00:00

  • The management of acute hypertension in patients with renal dysfunction: labetalol or nicardipine?

    abstract:STUDY OBJECTIVES:To compare the safety and efficacy of U.S. Food and Drug Administration (FDA)-recommended doses of labetalol and nicardipine for hypertension (HTN) management in a subset of patients with renal dysfunction (RD). DESIGN:Randomized, open label, multicenter prospective clinical trial. SETTING:Thirteen U...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.3810/pgm.2014.07.2790

    authors: Varon J,Soto-Ruiz KM,Baumann BM,Borczuk P,Cannon CM,Chandra A,Cline DM,Diercks DB,Hiestand B,Hsu A,Jois-Bilowich P,Kaminski B,Levy P,Nowak RM,Schrock JW,Peacock WF

    更新日期:2014-07-01 00:00:00

  • One-stage posterior approach for treating multilevel noncontiguous thoracic and lumbar spinal tuberculosis.

    abstract:OBJECTIVES:Multilevel noncontiguous thoracic and lumbar spinal tuberculosis (MNST) is a relatively rare entity. The objective of this retrospective study was to investigate whether a technique involving a one-stage posterior debridement and decompression, combined with an intervertebral fusion and posterior instrumenta...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.2019.1552824

    authors: Chen RS,Liao X,Xiong ML,Chen FR,Wang BW,Huang JM,Chen XL,Yin GH,Liu HY,Jin DD

    更新日期:2019-01-01 00:00:00

  • The metabolic syndrome: mechanisms, epidemiology, and clinical implications.

    abstract::This article reviews the definition, mechanisms, epidemiology, and clinical sequelae of the metabolic syndrome and explores potential relationships between the metabolic syndrome, type 2 diabetes, and cardiovascular disease. Definitions for the metabolic syndrome proposed by the World Health Organization and the Natio...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.3810/pgm.12.2003.suppl31.175

    authors:

    更新日期:2003-12-01 00:00:00

  • Gallstone symptoms. Myth and reality.

    abstract::Gallstones are very common, but at least two thirds of detected stones are asymptomatic and a large number undoubtedly go undetected. The presence of symptoms or complications is the indication for surgery. It is important to accurately identify which symptoms are caused by gallstones, because removing the gallbladder...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1991.11701076

    authors: Egbert AM

    更新日期:1991-10-01 00:00:00

  • Viral infections in the elderly. The challenges of managing herpes zoster, influenza, and RSV.

    abstract::Viral diseases are an important cause of morbidity and mortality in elderly patients, whether they live in the community or in long-term care facilities. Management of viral infections in older adults is complicated by factors that include the infrequency or absence of common signs and symptoms of infection and advers...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.3810/pgm.2005.11.1687

    authors: Bader MS,McKinsey DS

    更新日期:2005-11-01 00:00:00

  • The 'sweet killer'. Can you recognize the symptoms of ethylene glycol poisoning?

    abstract::Ingested ethylene glycol is readily absorbed and metabolized into toxic metabolites that can cause CNS depression, cardiopulmonary failure, and renal failure. Thorough history taking, physical examination, and laboratory testing are essential for diagnosis. Careful differential diagnosis is important because symptoms ...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.3810/pgm.1999.10.1.734

    authors: de Chazal I,Houghton B,Frock J

    更新日期:1999-10-01 00:00:00

  • Mechanisms and possible causes of Alzheimer's disease.

    abstract::Alzheimer's disease has been found to be genetically transmitted. Structural changes in the disease include loss of neurons, specifically cholinergic and perhaps noradrenergic neurons. Functional connections among neurons are also lost. No cause has yet been determined, but slow viruses, autoimmune processes, and alum...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1983.11698359

    authors: Schmidt G

    更新日期:1983-04-01 00:00:00

  • Charcot's disease in diabetic patients. Correct diagnosis can prevent progressive deformity.

    abstract::Although Charcot's disease and its association with diabetes have been described many times in the literature, it is still often misdiagnosed and incorrectly treated as osteomyelitis, arthritis, or gout. The best safeguard is a high index of suspicion. A warm, swollen foot in a diabetic patient with long-standing neur...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.1080/00325481.1991.11700869

    authors: Giurini JM,Chrzan JS,Gibbons GW,Habershaw GM

    更新日期:1991-03-01 00:00:00

  • Accuracy and clinical utility of a point-of-care HbA1c testing device.

    abstract:BACKGROUND:Point-of-care testing (POCT) is widely used to measure blood glucose levels in people with diabetes, although its use in measuring glycated hemoglobin (HbA1c) levels is less common, perhaps due to perceived performance issues and access to the technology. METHODS:Forty blood samples were analyzed in duplica...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.3810/pgm.2013.05.2664

    authors: Knaebel J,Irvin BR,Xie CZ

    更新日期:2013-05-01 00:00:00

  • Identifying psychiatrists' practice patterns when managing depression in patients with bipolar I disorder: a descriptive study to inform education needs.

    abstract:OBJECTIVE:The purpose of this study was to describe practice patterns of US psychiatrists with regard to the diagnosis and management of depression in adults with bipolar I disorder and to identify relevant gaps in clinical knowledge and competence. METHODS:Two focus groups were conducted using nominal group technique...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.3810/pgm.2013.01.2606

    authors: Glauser TA,Cerenzia W,Wiley S,Howson A,Thase M

    更新日期:2013-01-01 00:00:00

  • Facial pain. 'Why does my face hurt, doctor?'.

    abstract::In addition to sinus and dental abnormalities and stress, several different neurologic conditions can cause facial pain. These include various neuroalgias (trigeminal, vagoglosso-pharyngeal, cranial), carotodynia, and optic neuritis. Pain characteristics and results of specific neurologic tests establish the diagnosis...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.1080/00325481.1990.11704523

    authors: Mandel S

    更新日期:1990-01-01 00:00:00

  • Beneficial effects resulting from thiazolidinediones for treatment of type 2 diabetes mellitus.

    abstract::Because new drugs continue to be developed, physicians treating patients with type 2 diabetes have a wide range of agents from which to choose. The newest class, the thiazolidinediones (TZDs), should be a mainstay of treatment for most patients with type 2 diabetes, because these agents reduce insulin resistance as we...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:

    authors: Bell DS

    更新日期:2003-05-01 00:00:00

  • Cutaneous irritancy of an ibuprofen medicated plaster in healthy volunteers.

    abstract:OBJECTIVE:Ibuprofen is a commonly used non-steroidal anti-inflammatory drug administered to treat injuries, joint pain, and recurrent muscular skeletal pain. The aim of this study was to determine the cutaneous irritancy of a medicated ibuprofen plaster compared with a placebo plaster in healthy volunteers. METHODS:He...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.1080/00325481.2018.1398047

    authors: Maganji M,Connolly MP,Bhatt A

    更新日期:2018-01-01 00:00:00

  • Normal growth and development: current concepts.

    abstract::Human growth and development are a continuum starting at conception. Prenatal growth can only be estimated at present but is an important consideration in an evaluation of a child's developmental status. Postnatal growth can be assessed for size attained (distance curve) or change over time (velocity curve). Velocity ...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1977.11714699

    authors: Falkner F

    更新日期:1977-12-01 00:00:00

  • Ankylosing spondylitis.

    abstract::Preview Back pain can be a symptom of any number of problems, most commonly mechanical, or structural, in nature. Among the nonmechanical causes is ankylosing spondylitis, an inflammatory disease that involves the spine and sometimes other joints and extra-articular organs. Dr Escalante explains how to differentiate t...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1993.11945685

    authors: Escalante A

    更新日期:1993-07-01 00:00:00

  • Surgical treatment of reflux esophagitis and stricture.

    abstract::Surgical intervention is usually indicated in reflux esophagitis when medical therapy fails to control symptoms. Since most patients with peptic esophagitis also have a sliding hiatal hernia, early procedures focused on hernia repair. Weakness of the lower esophageal sphincter is now known to be the pathogenetic mecha...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1977.11712121

    authors: Woodward ER

    更新日期:1977-02-01 00:00:00

  • Cutaneous signs of internal malignancy. A pictorial essay.

    abstract::The skin is a window of internal malignancies and other diseases. The cutaneous signs of internal malignancy can be divided into four major groups: (1) hypersensitivity or toxic reactions, (2) infections, (3) metabolic disorders, and (4) tumors. A diagnosis of the many signs of systemic malignancy is made by inspectio...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1986.11699299

    authors: Bergfeld WF

    更新日期:1986-02-15 00:00:00

  • Hoarseness. From viral laryngitis to glottic cancer.

    abstract::Hoarseness indicates an abnormality at the level of the glottis. This symptom may result from either structural or physiologic disorders. The differential diagnosis is lengthy and includes both benign and malignant diseases. History taking and physical examination, particularly laryngeal visualization, provide key clu...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:

    authors: Dettelbach M,Eibling DE,Johnson JT

    更新日期:1994-04-01 00:00:00

  • Comorbidities in patients with irritable bowel syndrome with constipation or chronic idiopathic constipation: a review of the literature from the past decade.

    abstract:BACKGROUND:Irritable bowel syndrome with constipation (IBS-C) and chronic idiopathic constipation (CIC) are common functional bowel disorders. Patients with IBS-C or CIC often present with ≥ 1 comorbidity that coincides with either of these conditions. These comorbidities may make underappreciated contributions to the ...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.3810/pgm.2013.03.2640

    authors: Nellesen D,Chawla A,Oh DL,Weissman T,Lavins BJ,Murray CW

    更新日期:2013-03-01 00:00:00

  • Chemosensory dysfunction. Clinical evaluation results from a taste and smell clinic.

    abstract::Findings from 441 patient evaluations performed at the Taste and Smell Clinic of the Connecticut Chemosensory Clinical Research Center are presented. Taste and smell dysfunction was the chief complaint in all patients. The diagnostic approach included tests of taste and smell function; history taking; physical, neurol...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1987.11699680

    authors: Goodspeed RB,Gent JF,Catalanotto FA

    更新日期:1987-01-01 00:00:00

  • Non-Q wave myocardial infarction. Assessment and management of a unique and diverse subset.

    abstract::Acute cardiac events involving coronary symptoms, elevated enzyme levels, and electrocardiographic changes without the development of Q waves often result in higher rates of reinfarction and unstable angina than do more severe myocardial infarctions. The incidence of these non-Q wave events is on the rise, possibly be...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.3810/pgm.2000.02.890

    authors: Tamberella MR 3rd,Warner JG Jr

    更新日期:2000-02-01 00:00:00

  • Congenital cystic disease of the lung.

    abstract::A 15-year-old boy who had sharp pains in the right side of the chest and was unable to breathe deeply was tentatively diagnosed as having congenital cystic disease of the lung on the basis of chest x-ray studies and bronchography. The diagnosis was confirmed after thoracotomy and right lower lobectomy, carried out bec...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1984.11697960

    authors: Darrow GL

    更新日期:1984-03-01 00:00:00

  • Carotid artery stenosis. Selecting candidates for surgical management.

    abstract::Many patients with significant carotid artery stenosis are candidates for endarterectomy, a procedure now proved to reduce the incidence of future stroke and death. In this article, Drs Jaigobin and Perry describe an approach to patients with both symptomatic and asymptomatic carotid stenosis and review current indica...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:

    authors: Jaigobin CS,Perry JR

    更新日期:1994-10-01 00:00:00

  • Urologic emergencies. Conditions affecting the kidney, ureter, bladder, prostate, and urethra.

    abstract::Prompt, thorough evaluation is needed when patients present with symptoms of renal colic, acute urinary retention, prostatitis, pyelonephritis, and other urologic emergencies. Primary care physicians have an important role in initial workup and treatment. Once the diagnosis is determined, urologic consultation may be ...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.3810/pgm.1996.10.100

    authors: Samm BJ,Dmochowski RR

    更新日期:1996-10-01 00:00:00

  • Thyroid function tests. Guidelines for interpretation in common clinical disorders.

    abstract::While a wide variety of thyroid function tests are currently available, all are sometimes abnormal in patients without thyroid disease. To interpret test results properly, the clinician needs to be aware of factors altering thyroid function tests. In every instance, the clinician needs to begin by asking whether the p...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:

    authors: de los Santos ET,Mazzaferri EL

    更新日期:1989-04-01 00:00:00