Sickle cell disease.

abstract：OBJECTIVES:Lorcaserin is a selective 5-HT2C (5-hydroxytryptamine 2C) receptor agonist indicated for weight management. Here, we assess the impact of lorcaserin on progression from prediabetes to type 2 diabetes (T2D) and on reversion from prediabetes to euglycemia. METHODS:This is a post hoc analysis of pooled data fr...

journal_title：Postgraduate medicine

authors： Nesto R,Fain R,Li Y,Shanahan W

更新日期：2016-05-01 00:00:00

abstract：:Serum electrolyte levels by themselves may be difficult to interpret. For example, an abnormal serum potassium concentration cannot be understood without taking into account the patient's history, other serum electrolyte values, and possibly results of other laboratory tests. Knowledge of the principles of serum elect...

journal_title：Postgraduate medicine

authors： Kapsner CO,Tzamaloukas AH

更新日期：1991-12-01 00:00:00

abstract：:Although Charcot's disease and its association with diabetes have been described many times in the literature, it is still often misdiagnosed and incorrectly treated as osteomyelitis, arthritis, or gout. The best safeguard is a high index of suspicion. A warm, swollen foot in a diabetic patient with long-standing neur...

journal_title：Postgraduate medicine

authors： Giurini JM,Chrzan JS,Gibbons GW,Habershaw GM

更新日期：1991-03-01 00:00:00

abstract：:Knee and elbow injuries are seen frequently by the primary care physician and require prompt and careful treatment in order to prevent infection, preserve joint function, and avoid scarring. A thorough history and physical examination help to rule out more significant damage to the related joint, nerves, or tendons. I...

journal_title：Postgraduate medicine

authors： Stevenson TR,Smith DJ Jr

更新日期：1989-04-01 00:00:00

abstract：:Extracorporeal shock wave lithotripsy has become a valuable asset to the urologist and greatly benefits urologic stone patients. Eight years of clinical use have proven its clinical efficacy, with more than 400,000 successfully performed treatments worldwide. In a short period of time, ESWL has completely changed the ...

journal_title：Postgraduate medicine

authors： Cass AS

更新日期：1988-05-01 00:00:00

abstract：:Autonomic neural impulses that accompany discharges during a seizure can cause a variety of cardiac manifestations, including cardiac arrhythmias, sudden death, anginal chest pain, neurogenic pulmonary edema, and symptoms of pheochromocytoma. Either generalized or focal seizures may generate such signs and symptoms. A...

journal_title：Postgraduate medicine

authors： Kothari SS

更新日期：1990-11-01 00:00:00

abstract：:Primary carcinoid tumor of the thymus is a rare, slow-growing neoplasm occurring most commonly in middle-aged men. The usual clinical manifestations are those of a mediastinal mass, although in asymptomatic patients, the diagnosis may be suggested by a routine chest roentgenogram. Excision is the most common treatment...

journal_title：Postgraduate medicine

authors： Kogan J

更新日期：1984-01-01 00:00:00

abstract：:Considering that over half of Americans will die from cardiovascular disease, the over-whelming majority of those deaths being from atherosclerosis, we need to accept and act on the vast body of information derived from investigation of coronary risk factors. Identification of persons at risk needs to be done early--w...

journal_title：Postgraduate medicine

authors： Glatter TR

更新日期：1984-11-01 00:00:00

abstract：:Traveler's diarrhea affects a substantial number of travelers to high-risk areas of the world. The key to controlling this troublesome disease is prevention. The most important preventive measures depend on educating patients to consume only safe foods and pure water. Physicians cannot overemphasize the importance of ...

journal_title：Postgraduate medicine

authors： Strum WB

更新日期：1988-07-01 00:00:00

abstract：OBJECTIVES:The diagnosis of malignant pleural effusion (MPE) remains a clinical challenge. As a negative regulator of T-cell activation, cytotoxic T lymphocyte-associated antigen-4 (CTLA-4) has been associated with many malignant diseases. However, there is limited data about the relationship between CTLA-4 and MPE. Th...

journal_title：Postgraduate medicine

authors： Chen M,Xie S,Wan C,Zeng N,Wu Y,Qin J,Shen Y,Wen F

更新日期：2017-08-01 00:00:00

abstract：:Diarrhea is a common gastrointestinal problem in diabetes, and its prevalence has been underestimated. The cause of diabetic diarrhea is unknown, but it is probably related to gastrointestinal motility disturbances secondary to diabetic autonomic neuropathy. Other causes (especially primary malabsorption syndromes and...

journal_title：Postgraduate medicine

authors： Beebe DK,Walley E

更新日期：1992-06-01 00:00:00

abstract：:What clinical circumstances call for aggressive treatment of jaundice in newborns? Is cessation of breast-feeding necessary to help bring down the high bilirubin concentration? When should phototherapy be started--and stopped? The authors address these and other questions in this thorough guide to differential diagnos...

journal_title：Postgraduate medicine

authors： Lasker MR,Holzman IR

更新日期：1996-03-01 00:00:00

abstract：:Scleroderma, psoriasis, lichen planus, and other skin disorders may signal a more serious internal disease. Physicians who recognize such clues can initiate early treatment while disease is in its early stages. The authors of this article describe several of the more common dermatologic conditions linked to systemic d...

journal_title：Postgraduate medicine

authors： Kirsner RS,Federman DG

更新日期：1997-06-01 00:00:00

abstract：:Acute cardiac events involving coronary symptoms, elevated enzyme levels, and electrocardiographic changes without the development of Q waves often result in higher rates of reinfarction and unstable angina than do more severe myocardial infarctions. The incidence of these non-Q wave events is on the rise, possibly be...

journal_title：Postgraduate medicine

authors： Tamberella MR 3rd,Warner JG Jr

更新日期：2000-02-01 00:00:00

abstract：:Aspirin-induced hypersensitivity affects a substantial number of people, including 20% or more of asthmatic patients. A dramatic flare of symptoms occurs after indigestion of aspirin or a nonsteroidal anti-inflammatory drug, and symptoms can persist even after the agent is discontinued. Fortunately, aspirin desensitiz...

journal_title：Postgraduate medicine

authors： Manning ME,Stevenson DD

更新日期：1991-10-01 00:00:00

abstract：:Preview Few people can say they have never experienced some form of pressure-related changes while flying. Although uncommon on commercial flights, severe middle ear blocks do occur. Drawing from his experience treating military pilots, Dr Brown discusses the causes of barotrauma, steps that airline passengers can tak...

journal_title：Postgraduate medicine

authors： Brown TP

更新日期：1994-08-01 00:00:00

abstract：:A high index of suspicion and careful application of diagnostic methods are essential for accurate diagnosis of parasitic bowel diseases. The varied clinical spectrum of giardiasis, amebiasis, and strongyloidiasis emphasizes the need to consider these pathogens when patients present with gastrointestinal complaints. G...

journal_title：Postgraduate medicine

authors： Burns TW

更新日期：1982-05-01 00:00:00

abstract：:Hoarseness indicates an abnormality at the level of the glottis. This symptom may result from either structural or physiologic disorders. The differential diagnosis is lengthy and includes both benign and malignant diseases. History taking and physical examination, particularly laryngeal visualization, provide key clu...

journal_title：Postgraduate medicine

authors： Dettelbach M,Eibling DE,Johnson JT

更新日期：1994-04-01 00:00:00

abstract：:Unresolved grief refers either to the absence or to the prolongation of normal grief. It is identified by (1) painful response to recall of the deceased, (2) realization of not having accepted the loss or of not being able to grieve, and (3) unaccountable depression, emergence of medical symptoms on the anniversary of...

journal_title：Postgraduate medicine

authors： DeVaul RA,Zisook S

更新日期：1976-05-01 00:00:00

abstract：:Heparin and warfarin sodium (Coumadin, Panwarfin, Sofarin) are used most often to treat acute and recurrent venous thromboembolic disease, arterial disease, valvular heart disease, and atrial fibrillation. These agents along with dextran, pneumatic compression devices, and gradient stockings are also used to prevent d...

journal_title：Postgraduate medicine

authors： Dhami MS,Bona RD

更新日期：1991-07-01 00:00:00

abstract：:Irritable bowel syndrome (IBS), which is characterized by recurrent abdominal pain and disordered bowel habits, is one of the most common functional bowel disorders. IBS is a substantial burden on both patient health-related quality of life and healthcare costs. Several pathophysiologic mechanisms have been postulated...

journal_title：Postgraduate medicine

authors： Harris LA,Baffy N

更新日期：2017-11-01 00:00:00

abstract：:Diagnosing acute otitis media (AOM) is quite challenging for physicians and especially other healthcare providers. Although the new guidelines from the American Academy of Pediatrics/American Academy of Family Physicians provide some guidance for making the correct diagnosis of AOM, overdiagnosis will still remain a p...

journal_title：Postgraduate medicine

authors： Block SL

更新日期：2005-12-01 00:00:00

abstract：:Epileptiform seizures occurred in a 34-year-old woman who was receiving amitriptyline and lithium carbonate therapy for treatment of endogenous depression. While receiving amitriptyline maintenance therapy, she was given lithium on two separate occasions, and despite serum levels of lithium in the therapeutic range, g...

journal_title：Postgraduate medicine

authors： Solomon JG

更新日期：1979-09-01 00:00:00

abstract：:When a patient presents with a hard, painless lump in the neck, one should assume that it is a cancer and that it is metastatic from a primary lesion located above the clavicle. A careful physical examination with the appropriate instruments most often will determine the site of the primary lesion. Laryngograms or lat...

journal_title：Postgraduate medicine

authors： Devine KD

更新日期：1975-05-01 00:00:00

abstract：:Proximal gastric vagotomy without drainage is widely accepted in Great Britain and Europe but in the United States has been done mainly in university centers. The operation denervates the acid-secreting parietal cell mass of the stomach, preserving vagal innervation to the gastric antrum and extragastric abdominal vis...

journal_title：Postgraduate medicine

authors： Sawyers JL

更新日期：1978-04-01 00:00:00

abstract：:In a case of rheumatic disease, the patient's history and a careful physical examination should yield most of the information needed to identify the specific disorder present. A convenient classification is based on four differentiating features: number of joints affected, acuteness or chronicity of disease, absence o...

journal_title：Postgraduate medicine

authors： Weiss TE,Gum OB,Biundo JJ Jr

更新日期：1976-12-01 00:00:00

abstract：:Acute exacerbations of chronic obstructive pulmonary disease occur often. Severity should be established by signs and symptoms and by reference to baseline pulmonary function test results when necessary. If the exacerbation is mild to moderate, treatment should include antibiotics, theophylline, beta agonists, and muc...

journal_title：Postgraduate medicine

authors： Hagedorn SD

更新日期：1992-01-01 00:00:00

abstract：:Psoriasis, like diabetes, is a multifactorial genetic disease with complex interactions of deranged metabolism. Factors that affect epidermal differentiation and proliferation include cyclic nucleotide interactions, polyamine metabolism, cell surface--cytoskeleton interactions, and arachidonic acid--prostaglandin casc...

journal_title：Postgraduate medicine

authors： Anderson TF,Voorhees JJ

更新日期：1980-06-01 00:00:00

abstract：:Technical advances over the past few years have rapidly increased the possibilities for filmless radiology services provided by PACS. Such systems are also financially feasible for many healthcare practices, primarily because of the goals achieved through increased efficiency and improved patient care. In coming years...

journal_title：Postgraduate medicine

authors： Naul LG,Sincleair ST

更新日期：2001-06-01 00:00:00

abstract：:Pregabalin is one of the first-line treatments approved for the management of neuropathic pain (NeP). While many patients benefit from treatment with pregabalin, they are often treated with suboptimal doses, possibly due to unfamiliarity around prescribing the drug and/or side effects that can occur with up-titration....

journal_title：Postgraduate medicine

authors： Freynhagen R,Baron R,Kawaguchi Y,Malik RA,Martire DL,Parsons B,Rey RD,Schug SA,Jensen TS,Tölle TR,Ushida T,Whalen E

更新日期：2021-01-01 00:00:00