Endocarditis. Changing trends in epidemiology, clinical and microbiologic spectrum.

Abstract:

:Infective endocarditis refers to infection of the endocardium or heart valves by microbes, resulting in tissue destruction. Clinical presentation is quite variable, and a high level of suspicion is essential for recognition. Diagnosis is dependent on identification of the causative agent in blood cultures. Cultures that are persistently negative indicate the presence of culture-negative endocarditis, and diagnosis is one of exclusion. Treatment of endocarditis consists of high doses of antibiotics active against the infecting organism. Individualized therapy is the key to management.

journal_name

Postgrad Med

journal_title

Postgraduate medicine

authors

Nunley DL,Perlman PE

doi

10.1080/00325481.1993.11701672

subject

Has Abstract

pub_date

1993-04-01 00:00:00

pages

235-8, 241-4, 247

issue

5

eissn

0032-5481

issn

1941-9260

journal_volume

93

pub_type

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