Inflammatory particles stimulate thromboplastin production by human monocytes.

abstract：:Effects of mechanical trauma of platelets and red blood cells on dynamic viscoelasticity of blood during clotting were examined. Two different methods were attempted to give the mechanical damage to blood cells. In one method, a flow apparatus consisting of a thin teflon tube and two sample reservoirs connecting to bo...

journal_title：Thrombosis research

authors： Kaibara M,Ukiya Y,Sekiguchi M

更新日期：1986-08-15 00:00:00

abstract：:The activity of tissue plasminogen activator-plasminogen activator inhibitor-1 (t-PA-PAI-1) complex to convert plasminogen to plasmin was examined by using fibrin autography and casein zymography where plasminogen was added or removed for casein layer. Fibrin autography was more sensitive to the activity of t-PA even ...

journal_title：Thrombosis research

authors： Takada Y,Takada A

更新日期：1991-07-01 00:00:00

abstract：:Mass-Length ratio of fibrin fibres (microT and microP) derived independently from turbidity and permeability respectively, in networks made in fibrinogen solution and plasma, have been compared under similar conditions of clotting. Amount of fibrinogen conversion to fibrin was similar in both systems when high thrombi...

journal_title：Thrombosis research

authors： Shah GA,Nair CH,Dhall DP

更新日期：1987-02-01 00:00:00

abstract：INTRODUCTION:Elevated soluble urokinase-type plasminogen activator receptor (suPAR) indicates an inflammatory state caused by conditions such as HIV and cancer. Recently suPAR was identified as an indicator of cardiovascular disease (CVD). CVD is highly prevalent in black South Africans, but the potential role of suPAR...

journal_title：Thrombosis research

authors： Schutte AE,Myburgh A,Olsen MH,Eugen-Olsen J,Schutte R

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:The aim of this study was to describe platelet aggregation characteristics by multiple electrode aggregometry (MEA) and to evaluate MEA for its potential to detect platelet dysfunction and response to anti-aggregatory drugs in patients with myeloproliferative disorders (MPD). METHODS:We compared the platele...

journal_title：Thrombosis research

authors： Robier C,Neubauer M,Sternad H,Quehenberger F,Rainer F,Neumeister P

更新日期：2010-09-01 00:00:00

abstract：:The role of thrombin in vascular physiology and pathophysiology continues to impact our understanding of many cellular processes and systems including the function of platelets, endothelial cells, smooth muscle cells, leukocytes and the regulation of the coagulation cascade. Recent acute coronary syndrome clinical tri...

journal_title：Thrombosis research

authors： Giri S,Jennings LK

更新日期：2015-05-01 00:00:00

abstract：IMPORTANCE:Unprovoked venous thromboembolism (VTE) can be the first manifestation of cancer. It is unclear if extensive screening for occult cancer including a comprehensive computed tomography (CT) scan of the abdomen/pelvis is cost-effective in this patient population. OBJECTIVE:To assess the health care related cos...

journal_title：Thrombosis research

authors： Coyle K,Carrier M,Lazo-Langner A,Shivakumar S,Zarychanski R,Tagalakis V,Solymoss S,Routhier N,Douketis J,Coyle D

更新日期：2017-03-01 00:00:00

abstract：:We investigated on how to effectively administer orally factor VIII preparation to two patients with von Willebrand's disease as volunteers, and the following results were obtained: Bleeding time and aPTT were shortened, but no change of PT was observed. Factor VIII:C increased slightly, but no significant increase wa...

journal_title：Thrombosis research

authors： Sakuragawa N,Niiya K,Kondo S

更新日期：1985-06-15 00:00:00

abstract：INTRODUCTION:Sepsis is frequently complicated by disseminated intravascular coagulation (DIC), which promotes multiple organ dysfunctions and significantly increase the mortality of patients with sepsis. How bacteria cause DIC is not fully understood. Outer membrane vesicles (OMVs) are membrane-enclosed microvesicles r...

journal_title：Thrombosis research

authors： Wang E,Liu Y,Qiu X,Tang Y,Wang H,Xiao X,Chen F,Lu B

更新日期：2019-06-01 00:00:00

abstract：:To demonstrate that human alpha-thrombin is effectively inactivated by human antithrombin III (AT) during the production of a fibrin clot we measured the amount of alpha-thrombin activity which can be recovered from a clot generated from purified human proteins. We discovered that 0.05-0.07% of the original alpha-thro...

journal_title：Thrombosis research

authors： Naski MC,Shafer JA

更新日期：1993-03-01 00:00:00

abstract：:Factor Xa-catalyzed prothrombin activation occurs on cellular surfaces, including those of vascular endothelial cells. In a reconstituted model, endothelial cells and platelets acted synergistically to maximally activate prothrombin in the presence of Factor Xa. Synergism was observed at platelet concentrations less t...

journal_title：Thrombosis research

authors： Rodgers GM,Shuman MA

更新日期：1987-01-15 00:00:00

abstract：:The cerebral vascular supply is constructed to protect the cerebral hemispheres and brainstem from the consequences of blood flow cessation. Reversal of blood flow around local obstructions is a feature of the microvascular beds of the striatum and cerebral cortex. Cerebral capillaries of these beds consist of endothe...

journal_title：Thrombosis research

authors： del Zoppo GJ,Hallenbeck JM

更新日期：2000-05-01 00:00:00

abstract：INTRODUCTION:Global clotting assays may reflect an individual's net hemostatic balance and could contribute to prothrombotic and hemorrhagic risk assessment. In this research, a global assay that measures both coagulation and fibrinolytic capacities was developed and investigated. MATERIALS AND METHODS:In the Clot For...

journal_title：Thrombosis research

authors： Goldenberg NA,Hathaway WE,Jacobson L,Manco-Johnson MJ

更新日期：2005-01-01 00:00:00

abstract：:Dietary intake of fish oils, rich in the polyunsaturated fatty acids (PUFAs) docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), has given inconsistent results as to their influence on the plasma fibrinogen level (1, 2, 3, 4, 5, 6). In the present study we have examined the effects of various fatty acids, the ...

journal_title：Thrombosis research

authors： Kiserud CE,Kierulf P,Høstmark AT

更新日期：1995-10-01 00:00:00

abstract：:The effect of dalteparin, a low molecular weight heparin, on severely antithrombin III (ATIII)-decreased disseminated intravascular coagulation (DIC) model was compared with that of unfractionated heparin (heparin). The DIC model in rabbits was produced by continuous infusion of thrombin in combination with bolus inje...

journal_title：Thrombosis research

authors： Tazawa S,Ichikawa K,Misawa K,Fukuyama J,Hamano S,Miyata H,Sakuragawa N

更新日期：1995-12-01 00:00:00

abstract：:Washed human platelets were incubated with commercial factor VIII concentrate, or with purified factor VIII coagulant moiety. Platelets were then washed again and lysed by sonication. VIII:Ag and vWf:Ag were measured in the platelet lysate prior to and after incubation of the lysate with phospholipase C (PL-C). Platel...

journal_title：Thrombosis research

authors： Muntean W,Leschnik B,Haas J

更新日期：1987-02-15 00:00:00

abstract：:Heparin-induced thrombocytopenia (HIT) is a transient hypercoagulability state initiated, paradoxically, by the anticoagulant, heparin. It is characterized by antibody-induced activation of platelets, leading to thrombin generation. Many patients with HIT develop thrombosis; even when heparin is stopped because of "is...

journal_title：Thrombosis research

authors： Warkentin TE

更新日期：2003-05-01 00:00:00

abstract：BACKGROUND:Early aspirin treatment is widely used to inhibit platelet activity and to reduce morbidity and mortality in patients presenting with an acute myocardial infarction or a stroke. A number of different aspirin formulations have been used for this purpose; however, a comparison of their effectiveness in inhibit...

journal_title：Thrombosis research

authors： Schwertner HA,McGlasson D,Christopher M,Bush AC

更新日期：2006-01-01 00:00:00

abstract：:This study comprised 50 patients subjected to major abdominal surgery, of which 13 developed deep vein thrombosis (DVT) according to the 125I-fibrinogen test. Plasma was sampled preoperatively, for the specific analysis of tissue plasminogen activator (t-PA) before and during venous occlusion. The recently described f...

journal_title：Thrombosis research

authors： Mellbring G,Dahlgren S,Wiman B,Sunnegårdh O

更新日期：1985-07-15 00:00:00

abstract：INTRODUCTION:Management of pregnant women at risk for venous thromboembolism (VTE) remains complex. Guidelines do not definitively fix optimal strategies due to limited trial data. Our objective was to build an easy-to-use tool allowing individualised, risk-adapted prophylaxis. MATERIALS AND METHODS:A Delphi exercise ...

journal_title：Thrombosis research

authors： Chauleur C,Gris JC,Laporte S,Rancon F,Varlet MN,Decousus H,Mismetti P,STRATHEGE Group.

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND:Coagulopathy is a major cause of early death when arsenic trioxide (As(2)O(3)) therapy fails. In addition to the procoagulant properties of blast cells, the cytotoxic therapy may contribute to the coagulation disorders. The aim of the present study was to evaluate the possible impact of As(2)O(3) on membrane...

journal_title：Thrombosis research

authors： Zhou J,Li H,Fu Y,Shi J,Hou J,Zhang Y,Liu X,Song P

更新日期：2011-05-01 00:00:00

abstract：:Human fibrinogen exposed to 46.5 degrees C was subjected to gel permeation chromatography. The protein eluted in two distinct peaks. The first peak appeared in the void volume containing soluble fibrinogen aggregates, while the other peak represented monomeric fibrinogen. In contrast to the monomeric peak material, th...

journal_title：Thrombosis research

authors： Bennick A,Haddeland U,Brosstad F

更新日期：1996-04-15 00:00:00

abstract：BACKGROUND:Thrombosis and complement activation are pathogenic features of antiphospholipid syndrome (APS). Their molecular link is Plasma carboxypeptidase-B, also known as thrombin activatable fibrinolysis inhibitor (TAFIa), which plays a dual role: anti-fibrinolytic, by cleaving carboxyl-terminal lysine residues from...

journal_title：Thrombosis research

authors： Grosso G,Vikerfors A,Woodhams B,Adam M,Bremme K,Holmström M,Ågren A,Eelde A,Bruzelius M,Svenungsson E,Antovic A

更新日期：2017-10-01 00:00:00

abstract：INTRODUCTION:Venous thromboembolism (VTE) is a frequent clinical event in patients with gynecologic cancer. However, studies that exclusively address the incidence of VTE according the type of gynecologic cancer are poorly reported. OBJECTIVE:To analyze the incidence of VTE and the associated factors in women with dif...

journal_title：Thrombosis research

authors： Trugilho IA,Renni MJP,Medeiros GC,Thuler LCS,Bergmann A

更新日期：2020-01-01 00:00:00

abstract：:Fibrinogen is a hexameric glycoprotein consisting of two sets of three polypeptides (the Aα, Bβ, and γ chains, encoded by the three genes FGA, FGB, and FGG). It is involved in the final phase of the coagulation process, being the precursor of the fibrin monomers necessary for the formation of the hemostatic plug. Rare...

journal_title：Thrombosis research

authors： Asselta R,Robusto M,Platé M,Santoro C,Peyvandi F,Duga S

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:While post thrombotic syndrome (PTS) is increasingly recognized as a frequent and potentially serious complication of deep vein thrombosis (DVT) in children, limited information is available regarding predictors of PTS. METHODS:Using the Mayo Clinic Master Diagnostic Index, all pediatric patients (age 0 to ...

journal_title：Thrombosis research

authors： Kumar R,Rodriguez V,Matsumoto JM,Khan SP,Weaver AL,McBane RD,Beebe TJ,Heit JA

更新日期：2015-02-01 00:00:00

abstract：:The behavior of hemostatic system activation during protracted physical exercise is well known, but the duration of its modification is not yet defined. In order to evaluate the time of hemostatic system activation after prolonged strenuous endurance physical exercise (typical marathon race: 42.195 km, v=15.35 km/h; m...

journal_title：Thrombosis research

authors： Prisco D,Paniccia R,Bandinelli B,Fedi S,Cellai AP,Liotta AA,Gatteschi L,Giusti B,Colella A,Abbate R,Gensini GF

更新日期：1998-01-15 00:00:00

abstract：INTRODUCTION:Flow cytometry (FCM) is the most commonly used method for detection of platelet-derived microparticles (PDMPs), but it is poorly standardized and mainly used for "bedside" analyses in fresh samples. If PDMPs could be analyzed in previously frozen samples it would increase the usefulness of the method. Howe...

journal_title：Thrombosis research

authors： Mobarrez F,Antovic J,Egberg N,Hansson M,Jörneskog G,Hultenby K,Wallén H

更新日期：2010-03-01 00:00:00

abstract：:Fluorescein Dextran (FD) was shown to be transported at increased rates through partially denuded endothelial monolayer. Platelet binding to the partially denuded monolayer lowered transport rates to those comparable with intact endothelium. Inhibition of transport by platelet binding was not affected by the addition ...

journal_title：Thrombosis research

authors： Yagyu Y,Mineo C,Imanaka T,Ikegami S,Takano T

更新日期：1992-05-01 00:00:00

abstract：:Beta-thromboglobulin (beta-TG) is a platelet-specific protein present in the alpha-granules and secreted into the surrounding medium on cell activation. The sodium dodecyl sulphate-polyacrylamide gel electrophoresis (SDS-PAGE) of platelet releasate after inhibition of metalloproteinases with ethyleneglycol-bis-(beta-a...

journal_title：Thrombosis research

authors： Resmi KR,Krishnan LK

更新日期：2002-05-15 00:00:00