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Intercellular transport through a partially denuded arterial endothelial monolayer. Effect of platelets and PGI2.

Abstract：

:Fluorescein Dextran (FD) was shown to be transported at increased rates through partially denuded endothelial monolayer. Platelet binding to the partially denuded monolayer lowered transport rates to those comparable with intact endothelium. Inhibition of transport by platelet binding was not affected by the addition of isocarbacyclin (a stable derivative of PGI2). This result suggests that adherent platelets at the partial denudation site are sufficient to suppress transport of FD.

journal_name

Thromb Res

journal_title

Thrombosis research

authors

Yagyu Y,Mineo C,Imanaka T,Ikegami S,Takano T

doi

10.1016/0049-3848(92)90191-c

subject

Has Abstract

pub_date

1992-05-01 00:00:00

pages

215-22

issue

2-3

eissn

0049-3848

issn

1879-2472

pii

0049-3848(92)90191-C

journal_volume

66

pub_type

杂志文章

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