Abstract：
:Twenty Dacron grafts (10 crimped and 10 noncrimped) were studied with light microscopy, scanning electron microscopy, and transmission electron microscopy (TEM) 1 to 10 months after insertion into the canine thoracoabdominal aorta. Fibroblast-derived pseudointima maintained a smooth luminal lining that approximated the luminal cross-sectional area of the aorta. Turbulent flow at the corrugated surface of crimped grafts was reflected by the nonuniform alignment of the luminal cells. TEM demonstrated that fibroblasts, macrophages, vasa, and nerve fibers had infiltrated the interstices of the grafts. A zone of loose connective tissues and ground substances existed between the graft surface and the pseudointima and occupied the zone between the luminal cells and the body of the pseudointima. The core of the pseudointima consisted of dense fibrous connective tissue elements and myofibroblasts arranged in a laminated pattern. The luminal cells that were seen were myofibroblasts containing microvilli rather than true endothelial cells. A gradual transition of fibroblast to myofibroblast from the graft to the lumen existed. Myofibroblasts with active rough endoplasmic reticula and Golgi complexes were responsible for formation of ground substances and extracellular matrix. Our observation strongly suggests that the cellular lining in healed Dacron prostheses is derived from modified fibroblasts or multipotential cells. These cells have the capability of transforming into endothelioid and myoblastoid cells as dictated by the functional need.
journal_name
Surgeryjournal_title
Surgeryauthors
Sottiurai VS,Batson RCsubject
Has Abstractpub_date
1983-11-01 00:00:00pages
792-801issue
5eissn
0039-6060issn
1532-7361pii
0039-6060(83)90068-5journal_volume
94pub_type
杂志文章相关文献
SURGERY文献大全abstract：BACKGROUND:"Take the Volume Pledge" proposes restricting pancreatectomies to hospitals that perform ≥20 per year. Our purpose was to identify those factors that characterize patients at risk for loss of access to pancreatic cancer care with enforcement of volume standards. METHODS:Using the Healthcare Cost and Utiliza...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/j.surg.2016.07.017
更新日期：2017-03-01 00:00:00
abstract：BACKGROUND:The impact of the location of colorectal cancer on patient outcomes has been reported in several settings. The objective of this study was to assess the prognostic impact of the location of the primary colon cancer among patients with colorectal cancer peritoneal metastases undergoing complete cytoreductive ...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/j.surg.2018.07.027
更新日期：2019-02-01 00:00:00
abstract：BACKGROUND:Expendable autologous nerve available for repair of nerve injuries is limited. Cadaveric allografts could provide adequate nerve for grafting but are susceptible to rejection and currently require chronic systemic immunosuppression. METHODS:Age-matched Buffalo (RT1B) rats randomly assigned to 7 experimental...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1998-08-01 00:00:00
abstract：:Peripheral parenteral nutrition avoids the use of central lines and is a useful means of nutritional support for selected patients. Amino acids alone have been used for peripheral parenteral nutrition and have been shown to give near nitrogen equilibrium. The addition of small amounts of dextrose to amino acids furthe...
journal_title：Surgery
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1982-10-01 00:00:00
abstract：:Teratomas were observed in 85 infants and children. Fifty-eight (68%) were girls and 27 (32%) boys. Site of origin was sacrococcygeal in 55 patients (64.8%), mediastinal in ten (11.7%), gonadal in ten (11.7%), presacral in four (4.8%), retroperitoneal in three (3.5%), and cervical in three (3.5%). Sixty-seven (78.8%) ...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1976-09-01 00:00:00
abstract：:A prospective, randomized clinical trial of three treatment regimens: (1) Cytoxan, methotrexate, and 5-fluorouracil (CMF), (2) CMF plus the antiestrogen drug, tamoxifen (CMFT), and (3) CMFT plus bacillus Calmette-Guerin (BCG) vaccinations in women with stage 22 breast cancer is reported. All patients underwent mastect...
journal_title：Surgery
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1980-05-01 00:00:00
abstract：BACKGROUND:Studies of risk factors after pancreatoduodenectomy are few: some concern restricted populations and others are based on administrative data. METHODS:Multicenter clinical data were collected for 300 patients undergoing pancreatoduodenectomy to determine (by univariate and multivariate analysis) preoperative...
journal_title：Surgery
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1016/j.surg.2005.08.012
更新日期：2006-05-01 00:00:00
abstract：:From 1979 to 1990, 33 children required operative treatment for pancreatitis. Causes included ductal abnormalities (12 children), trauma (10 children), idiopathic (four children), gallstones (three children), drug-induced (three children), and tumor (one child). This study reviews the characteristics and outcome of th...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1991-10-01 00:00:00
abstract：:The early work of Dr. William Longmire with total gastrectomy for gastric carcinoma prompted us to initiate an aggressive surgical approach to gastric carcinoma in 1960: in curative resections radical total gastrectomy with hepaticoceliac-left gastric arterial node dissection was to be performed for tumors involving t...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1985-01-01 00:00:00
abstract：:The question still remains: What is best for the patient? It appears that whole organ or segmental pancreas transplantation can be carried out, giving anywhere from a 46% to an 84% 1-year pancreas survival rate. At the moment there is no clear-cut evidence that patient survival--at least in the short term--is any bett...
journal_title：Surgery
pub_type： 杂志文章,评审
doi：
更新日期：1989-12-01 00:00:00
abstract：:Between July 1978 and February 1987, 177 pancreas transplants were performed. The 1-year patient and graft survival rates for the first 100 transplants up to October 1984 were 88% and 27%, respectively. Since November 1984, duct drainage has been used for 74 of 77 transplants, bladder (BD) in 36 and enteric (ED) in 38...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1987-10-01 00:00:00
abstract：BACKGROUND:Little is known about the clinical significance and risk factors for incomplete liver restoration after partial hepatectomy, which is defined by a liver volume restoration of less than 100% of the original volume. METHODS:We retrospectively analyzed patients who underwent hepatic resection for liver tumors ...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/j.surg.2020.02.022
更新日期：2020-07-01 00:00:00
abstract：:The prevailing hypothesis of thyroid carcinogenesis is that thyroid-stimulating hormone (TSH) is a prime factor in the growth and possibly the genesis of thyroid carcinoma. On the other hand, Graves' disease is a hyperthyroid state caused presumably by human thyroid-stimulating immunoglobulin (HTSI), not TSH. However,...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1985-12-01 00:00:00
abstract：BACKGROUND:Heparin binding to platelet factor 4 (PF4) generates a new antigenic epitope. In an unpredictable fashion, as many as approximately 17% of patients treated with unfractionated heparin (UFH) and approximately 8% treated with low-molecular-weight heparin (LMWH) subsequently develop the anti-heparin-PF4 antibod...
journal_title：Surgery
pub_type： 杂志文章,评审
doi：10.1016/j.surg.2007.09.036
更新日期：2008-03-01 00:00:00
abstract：BACKGROUND:The prognostic significance of the leukocyte subsets in peripheral blood has not yet been investigated in hepatocellular carcinoma patients. We sought to clarify the prognostic value of preoperative peripheral blood leukocyte subset counts, especially the absolute monocyte count, in HCC patients who have und...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/j.surg.2005.10.009
更新日期：2006-06-01 00:00:00
abstract：:Use of dextrose in intravenous resuscitation fluids is common practice; however, this study indicates that 5% dextrose solutions, even if administered in physiologic quantities, greatly worsens the outcome of survivable cardiac arrest. Twelve adult male mongrel dogs were premedicated with morphine, anesthetized with h...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1986-09-01 00:00:00
abstract：BACKGROUND:Recent trends toward regionalization of complex surgical procedures may increase the risk for care fragmentation during readmissions. Conflicting conclusions have been reported regarding risk factors and consequences of nonindex readmissions (ie, readmission to a separate hospital than the one where surgery ...
journal_title：Surgery
pub_type： 杂志文章,meta分析
doi：10.1016/j.surg.2018.08.021
更新日期：2019-03-01 00:00:00
abstract：BACKGROUND:Recent emphasis in medical education has been to encourage students to pursue primary care careers. This could have a negative impact on applications to surgical residencies. METHODS:To determine what factors are most influential for a student to pursue a surgical career in spite of this environment, third-...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1067/msy.2000.108214
更新日期：2000-08-01 00:00:00
abstract：BACKGROUND:The landscape of patients with end-stage renal disease is changing with the increasing availability of kidney transplantation. In the near future, a less aggressive approach to treat secondary hyperparathyroidism might be beneficial. We report outcomes of parathyroidectomy for end-stage renal disease-related...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/j.surg.2020.08.014
更新日期：2021-02-01 00:00:00
abstract：BACKGROUND:Solid pseudopapillary neoplasm of the pancreas is a distinctive pancreatic neoplasm with low metastatic potential. This study examines clinical differences and prognosis between male and female patients. METHODS:The medical records of 34 consecutive patients with pancreatic solid pseudopapillary neoplasms b...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/j.surg.2007.07.030
更新日期：2008-01-01 00:00:00
abstract：:Segmental bilioenteric anastomosis procedures were performed on 22 patients with malignant hilar biliary obstructions. The majority of the bypasses were done to the segment 3 duct and a single anastomosis was performed in each patient. The operative mortality rate was 13.6% and morbidity, 27.3%. The biliary obstructio...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1988-09-01 00:00:00
abstract：BACKGROUND:The carcinogenic effect of duodenoesophageal reflux, gastroesophageal reflux, and nitrosamines was studied in the rat esophagus. METHODS:Twenty male Sprague-Dawley rats underwent esophagogastroplasty to produce gastroesophageal reflux and 60 underwent duodenoesophageal anastomosis to produce duodenoesophage...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1992-05-01 00:00:00
abstract：:Minced adult human, rat, and dog pancreatic fragments were cultured under various conditions in an attempt to selectively purify pancreatic islet tissue from exocrine digestive enzymes. Islet purification was assessed by measuring tissue insulin and amylase concentrations, proportional to islet beta cell mass and exoc...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1976-08-01 00:00:00
abstract：BACKGROUND:Previous studies using simulation-based curricula have focused largely on technical skills. We developed a set of simulation-based modules that focus on intraoperative decision making. The objective of this study was to conduct a faculty evaluation of: (1) the usefulness of 4 newly developed, simulation-base...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/j.surg.2010.10.010
更新日期：2011-04-01 00:00:00
abstract：BACKGROUND:The risk of dying from primary hyperparathyroidism (pHPT) is controversial and has been explored mainly in single parathyroid gland disease. The present study investigates mortality in pHPT due to multiple parathyroid gland disease. METHODS:We used the nationwide Swedish In-patient Register and Cause-of-Dea...
journal_title：Surgery
pub_type： 杂志文章,多中心研究
doi：10.1016/j.surg.2004.05.044
更新日期：2004-11-01 00:00:00
abstract：BACKGROUND:The natural history of peripheral atherosclerosis in young adults appears to be unfavorable compared with that in older patients. No universally accepted definition of "premature" atherosclerosis exists, however, making comparison of clinical studies difficult. This study examined age-related differences in ...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/s0039-6060(05)80273-9
更新日期：1995-11-01 00:00:00
abstract：:The ability of the lung to decrease blood flow to an atelectatic lobe and to increase flow to normal after reinflation was investigated with a model using left lower lobe atelectasis (LLLA) in the dog. The change in the shunt fraction QS/Qt with continuing LLLA was assumed to represent a change in blood flow to the LL...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1977-07-01 00:00:00
abstract：BACKGROUND:In the evaluation of patients with primary hyperparathyroidism (PHP), specific query for a personal or family history of MEN1 (Hx) is recommended widely, but responses are rarely positiv. We instituted a 6-question panel (6Q) to routinely screen for MEN1 preoperatively. METHODS:The clinical database entries...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/j.surg.2008.07.030
更新日期：2008-12-01 00:00:00
abstract：BACKGROUND:After resection of advanced abdominal neuroblastoma, children may have persistent postoperative diarrhea. Until recently, the magnitude of this problem had not been appreciated. METHODS:To assess the incidence, severity, and management of chronic postoperative diarrhea in these patients, we reviewed the cas...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1067/msy.1998.88092
更新日期：1998-05-01 00:00:00
abstract：:Local low-dose streptokinase infusion (5000 to 6000 IU/hr) as compared to systemic streptokinase infusion (loading dose 250,000 IU/hr, maintenance dose 100,000 IU/hr) successfully relieved a total thrombotic abdominal aortic occlusion. No complications of bleeding or distal embolization occurred during streptokinase t...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1983-04-01 00:00:00
