Results of an aggressive surgical approach to gastric carcinoma during a twenty-three-year period.

Abstract:

:The early work of Dr. William Longmire with total gastrectomy for gastric carcinoma prompted us to initiate an aggressive surgical approach to gastric carcinoma in 1960: in curative resections radical total gastrectomy with hepaticoceliac-left gastric arterial node dissection was to be performed for tumors involving the entire stomach or upper two thirds and radical 80% to 90% subtotal gastrectomy with similar node dissection for tumors located in the antrum. During a 23-year period 213 patients with confirmed gastric carcinoma were studied. Celiotomy was performed in 192: advanced gastric cancer was found in 185 and seven had early gastric cancer. In only 80 patients could resections for "cure" be done. In 31 patients who underwent total or extended total gastrectomy the operative mortality rate was 9.6%, and life table survival curves show a better survival rate than in 49 patients treated by subtotal gastrectomy, with an operative mortality rate of 16.3%. The study shows the urgent need for diagnosis of early gastric cancer by gastroscopic screening of adults at risk and the meager salvage by radical resection in advanced disease.

journal_name

Surgery

journal_title

Surgery

authors

Scott HW Jr,Adkins RB Jr,Sawyers JL

subject

Has Abstract

pub_date

1985-01-01 00:00:00

pages

55-9

issue

1

eissn

0039-6060

issn

1532-7361

journal_volume

97

pub_type

杂志文章

相关文献

SURGERY文献大全
  • Corticosteroids increase blood interleukin-10 levels during cardiopulmonary bypass in men.

    abstract:BACKGROUND:Interleukin (IL)-10 is a potent antiinflammatory cytokine inhibiting the release of tumor necrosis factor--alpha (TNF-alpha) and IL-8 by activated macrophages and polymorphonuclear leukocytes. Cardiopulmonary bypass (CPB) represents a unique situation where an inflammatory reaction is predictably induced. Th...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1016/s0039-6060(96)80217-0

    authors: Tabardel Y,Duchateau J,Schmartz D,Marécaux G,Shahla M,Barvais L,Leclerc JL,Vincent JL

    更新日期:1996-01-01 00:00:00

  • Comparison of intraoperative iPTH assay (QPTH) criteria in guiding parathyroidectomy: which criterion is the most accurate?

    abstract:BACKGROUND:The quick parathyroid hormone assay (QPTH) reliably measures intact parathyroid hormone (iPTH) levels intraoperatively. The accuracy in predicting postoperative calcemia is related to blood sample timing and the criteria applied. To improve specificity or to decrease the cost of QPTH, several criteria have b...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1016/j.surg.2003.06.001

    authors: Carneiro DM,Solorzano CC,Nader MC,Ramirez M,Irvin GL 3rd

    更新日期:2003-12-01 00:00:00

  • Estimation of blood loss is inaccurate and unreliable.

    abstract:BACKGROUND:To determine the characteristics associated with improved accuracy or reliability of estimating operative blood loss. METHODS:Operating room personnel at a tertiary care hospital evaluated 3 operative simulations and provided estimations of blood loss. The simulations utilized precise, known volumes of porc...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1016/j.surg.2016.06.006

    authors: Rothermel LD,Lipman JM

    更新日期:2016-10-01 00:00:00

  • Selected management of pancreatic pseudocysts: operative versus expectant management.

    abstract:BACKGROUND:The aim of this study was to determine if nonoperative, noninterventional expectant management of pancreatic pseudocysts is warranted in selected patients. METHODS:From 1980 to 1985, 114 patients with the diagnosis of pancreatic pseudocyst were evaluated. RESULTS:Forty-six patients underwent primary operat...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:

    authors: Vitas GJ,Sarr MG

    更新日期:1992-02-01 00:00:00

  • Impact of residual nodal involvement after complete tumor response in patients undergoing neoadjuvant (chemo)radiotherapy for rectal cancer.

    abstract:BACKGROUND:The management of patients with a complete clinical response after neoadjuvant therapy for rectal adenocarcinoma is controversial. Those who advocate for resection point out the inaccuracy of N-staging with current imaging modalities. The objective of this study is to determine the impact of residual nodal i...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1016/j.surg.2019.03.026

    authors: Erkan A,Mendez A,Trepanier M,Kelly J,Nassif G,Albert MR,Lee L,Monson JRT

    更新日期:2019-10-01 00:00:00

  • Excision of underlying fascia with a primary malignant melanoma: effect on recurrence and survival rates.

    abstract::Patients with stages O and I malignant melanomas of the trunk and proximal limbs, having had wide excisions only without lymph node dissections, were reviewed to determine whether the presence or absence of muscle fasciae correlated with prognosis. Prior to 1969 most patients seen at The University of Texas M. D. Ande...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:

    authors: Kenady DE,Brown BW,McBride CM

    更新日期:1982-10-01 00:00:00

  • Comparison of the 7th and 8th editions of the American Joint Committee on Cancer Staging Systems for perihilar cholangiocarcinoma.

    abstract:BACKGROUND:The performances of the American Joint Committee on Cancer staging systems of the 7th and 8th edition were compared using a cohort of patients undergoing surgery for perihilar cholangiocarcinoma at 2 tertiary referral Italian hepatobiliary centers. METHODS:The American Joint Committee on Cancer 7th and 8th ...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1016/j.surg.2018.03.012

    authors: Ruzzenente A,Bagante F,Ardito F,Campagnaro T,Scoleri I,Conci S,Iacono C,Giuliante F,Guglielmi A

    更新日期:2018-08-01 00:00:00

  • Positive contrast herniography in adult patients with obscure groin pain.

    abstract::To evaluate its clinical benefit in adults, herniography was used in 73 patients with clinically unexplained groin pain. Hernias were demonstrated on the side with symptoms in 26 patients (36%). Relief of groin pain was registered in 16 of 17 patients who subsequently underwent operation. We consider herniography to b...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:

    authors: Ekberg O,Blomquist P,Olsson S

    更新日期:1981-05-01 00:00:00

  • Females have fewer complications and lower mortality following trauma than similarly injured males: a risk adjusted analysis of adults in the National Trauma Data Bank.

    abstract:BACKGROUND:Studies of sexual dimorphism in trauma outcomes suggest that women have a survival advantage compared to equivalently injured men. It is unknown if this gender disparity is mediated by potentially life-threatening complications. OBJECTIVE:To determine (1) if there is a sex-based differences in the odds of d...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1016/j.surg.2009.05.006

    authors: Haider AH,Crompton JG,Oyetunji T,Stevens KA,Efron DT,Kieninger AN,Chang DC,Cornwell EE 3rd,Haut ER

    更新日期:2009-08-01 00:00:00

  • Intercellular adhesion molecule-1 promotes neutrophil-mediated cytotoxicity.

    abstract:BACKGROUND:Interaction of the CD11/CD18 complex on polymorphonuclear neutrophils (PMNs) and intercellular adhesion molecule (ICAM)-1 on endothelium is a critical event in PMN-mediated tissue injury. In addition, increased expression of ICAM-1 on type I pneumocytes has been identified in a variety of pulmonary disorders...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1016/s0039-6060(05)80320-4

    authors: Barnett CC,Moore EE,Moore FA,Biffl WL,Smith MF Jr,Carl VS

    更新日期:1995-08-01 00:00:00

  • Prognostic significance of tumor DNA content in carcinoma of the hepatic duct confluence.

    abstract:BACKGROUND:In an attempt to identify prognostic factors in carcinoma of the hepatic duct confluence, the value of tumor DNA content was studied in 58 patients with this type of malignancy. METHODS:Of 58 patients (ages 26 to 74 years) surgically treated for carcinoma of the hepatic duct confluence, tumor DNA content wa...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:

    authors: Sato Y,van Gulik TM,Bosma A,Lygidakis NJ,Koyama K,van der Heyde MN

    更新日期:1994-04-01 00:00:00

  • N-ras mutation: an independent prognostic factor for aggressiveness of papillary thyroid carcinoma.

    abstract:BACKGROUND:The clinical importance of point mutations of ras oncogene in differentiated thyroid cancers has not been fully clarified. The purpose of this study is to determine the prognostic importance of ras mutation in papillary thyroid carcinoma. METHODS:Tumors of 91 patients with papillary carcinoma were studied; ...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:

    authors: Hara H,Fulton N,Yashiro T,Ito K,DeGroot LJ,Kaplan EL

    更新日期:1994-12-01 00:00:00

  • Surgery as primary treatment in patients with liver metastases from carcinoid tumors: a retrospective, unicentric study over 13 years.

    abstract:BACKGROUND:The heterogeneous nature of carcinoid tumors makes it difficult to develop a standardized treatment strategy for the primary tumor itself and for probable liver metastases. However, prolongation of the 5-year survival rate (5-ysr) and amelioration of the incapacitating symptoms after resection of the primary...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1067/msy.2001.110426

    authors: Nave H,Mössinger E,Feist H,Lang H,Raab H

    更新日期:2001-02-01 00:00:00

  • Splanchnic and total body oxygen consumption differences in septic and injured patients.

    abstract::The splanchnic and total body oxygen exchange and flow dynamics for injured patients (n = 7) and patients with sepsis and stable vital signs (n = 12) were studied. All patients were judged to be in the hyperdynamic phase of the stress response. In both patient groups 27% to 28% of the cardiac index was directed to the...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:

    authors: Dahn MS,Lange P,Lobdell K,Hans B,Jacobs LA,Mitchell RA

    更新日期:1987-01-01 00:00:00

  • Morbidity and mortality in patients with esophageal atresia.

    abstract:BACKGROUND:This study reports national estimates of population characteristics and outcomes for patients with esophageal atresia with or without tracheoesophageal fistula (EA/TEF) and evaluates the relationships between hospital volume and outcomes. METHODS:Patients admitted within 30 days of life who had Internationa...

    journal_title:Surgery

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.surg.2014.03.016

    authors: Sulkowski JP,Cooper JN,Lopez JJ,Jadcherla Y,Cuenot A,Mattei P,Deans KJ,Minneci PC

    更新日期:2014-08-01 00:00:00

  • Use and prognostic value of staging mediastinoscopy in non-small-cell lung cancer.

    abstract::One hundred sixty patients had preoperative mediastinoscopy, resection of the primary tumor, and complete mediastinal lymphadenectomy for non-small-cell carcinoma of the lung. Minimum follow-up was 24 months (mean 40 months). Postoperative staging based on histologic examination of the specimen of the lung and mediast...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:

    authors: Albertucci M,DeMeester TR,Golomb HM,MacMahon HK,Ryan JW,Iascone C

    更新日期:1987-10-01 00:00:00

  • Selective stripping operation based on Doppler ultrasonic findings for primary varicose veins of the lower extremities.

    abstract::In 337 limbs (208 patients) with primary varicose veins, Doppler ultrasound was used to detect reverse flow in the saphenous veins caused by manual compression of the calf. According to the extent of reverse flow in the saphenous trunks, varicosities of the long saphenous vein were classified into five types and the s...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:

    authors: Koyano K,Sakaguchi S

    更新日期:1988-06-01 00:00:00

  • Pheochromocytoma: operative strategy.

    abstract::We studied 28 patients who had undergone 30 operations for pheochromocytoma since 1964. The tumor types included bilateral, extra-adrenal, malignant, recurrent, and multiple endocrine neoplasia, with 20 tumors confined to the adrenal gland. The preoperative studies used to localize the tumor included ultrasonography, ...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:

    authors: Cullen ML,Staren ED,Straus AK,Doolas A,Shah R,Patel S,Economou SG

    更新日期:1985-11-01 00:00:00

  • Fostering a culture of innovation in academic surgery.

    abstract::Dr McCarthy is a fellow in cardiothoracic surgery at the University of Washington. During his general surgery training at Northwestern University, he completed a research fellowship in surgical innovation and obtained masters' degrees with a focus on health enterprise management, entrepreneurship, and innovation. ...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1016/j.surg.2016.08.035

    authors: McCarthy DP

    更新日期:2017-04-01 00:00:00

  • Induction of donor-specific tolerance to rat nerve allografts with portal venous donor alloantigen and anti-ICAM-1/LFA-1 monoclonal antibodies.

    abstract:BACKGROUND:Expendable autologous nerve available for repair of nerve injuries is limited. Cadaveric allografts could provide adequate nerve for grafting but are susceptible to rejection and currently require chronic systemic immunosuppression. METHODS:Age-matched Buffalo (RT1B) rats randomly assigned to 7 experimental...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:

    authors: Genden EM,Mackinnon SE,Yu S,Flye MW

    更新日期:1998-08-01 00:00:00

  • Resection of leiomyosarcoma originating in internal iliac vein and extending into heart via inferior vena cava.

    abstract::A patient's condition was initially diagnosed as constrictive pericarditis, but an echocardiogram revealed the presence of an intracardiac tumor. The tumor was a slow-growing leiomyosarcoma that originated in the left internal iliac vein, extended into the inferior vena cava, and reached the right ventricle. This tumo...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:

    authors: Kaku K,Kawashima Y,Kitamura S,Nakano S,Mori T,Beppu SU,Kozuka T,Sakurai M,Katayama S,Tanizawa O,Sonoda T

    更新日期:1981-05-01 00:00:00

  • Enhanced survival from cecal ligation and puncture with pentoxifylline is associated with altered neutrophil trafficking and reduced interleukin-1 beta expression but not inhibition of tumor necrosis factor synthesis.

    abstract:BACKGROUND:Our preliminary results showed that pentoxifylline improves survival after cecal ligation and puncture (CLP), even though in this model inhibition of tumor necrosis factor (TNF) activity decreases survival. In this study we tested the hypothesis that pentoxifylline improves survival after CLP, not by inhibit...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:

    authors: Hadjiminas DJ,McMasters KM,Robertson SE,Cheadle WG

    更新日期:1994-08-01 00:00:00

  • Sphincter of Oddi botulinum toxin injection to prevent pancreatic fistula after distal pancreatectomy.

    abstract:BACKGROUND:Postoperative pancreatic fistula represents the most important complication after distal pancreatectomy. The aim of this study was to evaluate the use of a preoperative endoscopic injection of botulinum toxin into the sphincter of Oddi to prevent postoperative pancreatic fistula (German Clinical Trials Regis...

    journal_title:Surgery

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.surg.2016.09.005

    authors: Hackert T,Klaiber U,Hinz U,Kehayova T,Probst P,Knebel P,Diener MK,Schneider L,Strobel O,Michalski CW,Ulrich A,Sauer P,Büchler MW

    更新日期:2017-05-01 00:00:00

  • Recovery of liver function in two-third partial hepatectomized rats evaluated by L-[1-13C]phenylalanine breath test.

    abstract:BACKGROUND:We have previously reported that by means of a breath test with intravenously administered L-[1-13C] phenylalanine (13Cphe), hepatopathy could be quantitatively evaluated by measuring expiratory 13CO2 levels in a short period. It is known that phenylalanine hydroxylase activity (PAHA) plays an important role...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1067/msy.2002.127947

    authors: Ishii Y,Asai S,Kohno T,Ito A,Iwai S,Ishikawa K

    更新日期:2002-11-01 00:00:00

  • Risk factors for the development of fulminant Clostridium difficile colitis.

    abstract:BACKGROUND:The development of fulminant Clostridium difficile colitis (FCDC) requires prompt operative intervention and is associated with a high mortality rate. The aim of this study was to use a case-control design to define the clinical and laboratory parameters that predict which patients with Clostridium difficile...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1016/j.surg.2007.12.008

    authors: Greenstein AJ,Byrn JC,Zhang LP,Swedish KA,Jahn AE,Divino CM

    更新日期:2008-05-01 00:00:00

  • Concordance of surgical clerkship performance and National Board of Medical Examiners Part II subtest scores. A validation model.

    abstract::This study compares the National Board of Medical Examiners Part II (NBME II) subtest scores of medical students attaining honors in a clinical clerkship to those of students receiving a passing score to determine if the NBME II examinations could be considered independently as valid indicators of clinical achievement...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:

    authors: Benenson TF,Stimmel B,Aufses A Jr

    更新日期:1981-06-01 00:00:00

  • Pancreaticoduodenal endocrine tumors in multiple endocrine neoplasia type 1: surgery or surveillance?

    abstract:BACKGROUND:The management of pancreaticoduodenal endocrine tumors (PETs) remains controversial in multiple endocrine neoplasia type 1 (MEN 1). METHODS:Twenty-one patients with MEN 1 and PETs were analyzed for outcome of surgery and surveillance with special regard to the genotype based on MEN1 gene mutation analysis. ...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1067/msy.2000.109727

    authors: Bartsch DK,Langer P,Wild A,Schilling T,Celik I,Rothmund M,Nies C

    更新日期:2000-12-01 00:00:00

  • Effect of very delayed repair of congenital diaphragmatic hernia on survival and extracorporeal life support use.

    abstract:BACKGROUND:Since November 1992, operative repair in neonates with congenital diaphragmatic hernia (CDH) at this institution was delayed until respiratory insufficiency had resolved. METHODS:A retrospective analysis was performed (n = 33) comparing delayed repair with our previously reported institutional experience wi...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1016/s0039-6060(96)80029-8

    authors: Reickert CA,Hirschl RB,Schumacher R,Geiger JD,Cox C,Teitelbaum DH,Polley TZ Jr,Harmon CM,Lelli JL,Coran AG

    更新日期:1996-10-01 00:00:00

  • Thrombogenicity of a fibronectin-coated, experimental polytetrafluoroethylene graft.

    abstract::To determine if pretreatment of polytetrafluoroethylene (PTFE) vascular grafts with fibronectin (FN) increased platelet adherence to them and adversely affected their patency, we labeled autologous canine platelets with indium III-oxine and interposed a FN-coated, experimental, 4 mm inner diameter, 10 cm long PTFE pro...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:

    authors: Kempczinski RF,Ramalanjaona GR,Douville C,Silberstein EB

    更新日期:1987-04-01 00:00:00

  • Internal biliary drainage improves decreased number of gut mucosal T lymphocytes and MAdCAM-1 expression in jaundiced rats.

    abstract:BACKGROUND:Although the effect of preoperative biliary drainage in patients with obstructive jaundice is controversial, bacterial or endotoxin translocation is one of the main postoperative problem in jaundiced patients. Failure in gut barrier functions causes bacterial translocation; homing and distribution of T lymph...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1016/j.surg.2004.02.001

    authors: Sano T,Ajiki T,Takeyama Y,Kuroda Y

    更新日期:2004-09-01 00:00:00