Response of an abdominal aortic thrombotic occlusion to local low-dose streptokinase therapy.

Abstract:

:Local low-dose streptokinase infusion (5000 to 6000 IU/hr) as compared to systemic streptokinase infusion (loading dose 250,000 IU/hr, maintenance dose 100,000 IU/hr) successfully relieved a total thrombotic abdominal aortic occlusion. No complications of bleeding or distal embolization occurred during streptokinase therapy, which required only 8 days of hospitalization. When seen at 4 months after streptokinase infusion, the patient was still free of symptoms. When no immediate threat of ischemic limb loss exists, streptokinase may offer a promising therapeutic alternative to surgical intervention for patients who represent a poor operative risk.

journal_name

Surgery

journal_title

Surgery

authors

Cunningham MW,May S,Tucker WY,Gerlock AJ Jr

subject

Has Abstract

pub_date

1983-04-01 00:00:00

pages

541-4

issue

4

eissn

0039-6060

issn

1532-7361

pii

0039-6060(83)90376-8

journal_volume

93

pub_type

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