Abstract:
:We aimed to describe anthropometric differences in weight-related disorders between adults with Down syndrome (DS) and healthy controls, as well as their disparate impact on glucose and lipid metabolism disorders. We underwent a cross-sectional study of 49 consecutively selected, community-residing adults with DS and 49 healthy controls in an outpatient clinic of a tertiary care hospital in Madrid, Spain. Siblings of adults with DS were studied as controls in 42 cases. Epidemiological data (age and gender), anthropometric data (body mass index, waist circumference, and waist-to-height ratio [WHR]), coexisting clinical conditions, and laboratory data (fasting glucose, insulin, glycated hemoglobin, creatinine, thyroid hormones, and lipid profile) were measured and compared between the groups. Adults with DS were significantly younger and more often male, with a higher prevalence of overweight and obesity than controls. Adults with DS also had a higher WHR, and more frequently presented abdominal obesity. Moreover, insulin resistance measured using the homeostatic model assessment was more prevalent among adults with DS and abdominal obesity. However, lipid profiles were similar between groups. The kappa correlation index for the diagnosis of abdominal obesity between waist circumference and WHR was 0.24 (95%CI: 0.13-0.34). We concluded that the prevalence of overweight, obesity, and abdominal obesity was higher in adults with DS than in controls. Adults with DS and abdominal obesity showed higher indexes of insulin resistance than their non-obese peers. WHR was a useful tool for the evaluation of abdominal obesity in this population.
journal_name
Res Dev Disabiljournal_title
Research in developmental disabilitiesauthors
Real de Asua D,Parra P,Costa R,Moldenhauer F,Suarez Cdoi
10.1016/j.ridd.2014.07.038subject
Has Abstractpub_date
2014-11-01 00:00:00pages
2942-9issue
11eissn
0891-4222issn
1873-3379pii
S0891-4222(14)00314-Xjournal_volume
35pub_type
杂志文章abstract::Reading grade level and readability are rarely considered as important variables in the implementation and outcome of behavior treatment plans. In the first of two studies, we analyzed the reading level and readability of 20 behavior treatment plans developed by certified behavior analysts. We found that the behavior ...
journal_title:Research in developmental disabilities
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journal_title:Research in developmental disabilities
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journal_title:Research in developmental disabilities
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journal_title:Research in developmental disabilities
pub_type: 临床试验,杂志文章,随机对照试验
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journal_title:Research in developmental disabilities
pub_type: 杂志文章
doi:10.1016/s0891-4222(98)00020-1
更新日期:1998-11-01 00:00:00
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journal_title:Research in developmental disabilities
pub_type: 杂志文章
doi:10.1016/s0891-4222(01)00083-x
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journal_title:Research in developmental disabilities
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ridd.2016.04.005
更新日期:2016-08-01 00:00:00
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journal_title:Research in developmental disabilities
pub_type: 杂志文章
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journal_title:Research in developmental disabilities
pub_type: 杂志文章
doi:10.1016/j.ridd.2012.03.031
更新日期:2013-01-01 00:00:00
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journal_title:Research in developmental disabilities
pub_type: 杂志文章
doi:10.1016/0891-4222(96)00015-7
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journal_title:Research in developmental disabilities
pub_type: 杂志文章
doi:10.1016/j.ridd.2013.11.009
更新日期:2014-02-01 00:00:00
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journal_title:Research in developmental disabilities
pub_type: 杂志文章
doi:10.1016/j.ridd.2012.09.011
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更新日期:2021-01-01 00:00:00
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journal_title:Research in developmental disabilities
pub_type: 临床试验,杂志文章
doi:10.1016/j.ridd.2011.04.008
更新日期:2011-09-01 00:00:00
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journal_title:Research in developmental disabilities
pub_type: 杂志文章
doi:10.1016/j.ridd.2014.03.044
更新日期:2014-07-01 00:00:00
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journal_title:Research in developmental disabilities
pub_type: 杂志文章
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journal_title:Research in developmental disabilities
pub_type: 杂志文章,评审
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journal_title:Research in developmental disabilities
pub_type: 杂志文章
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更新日期:1990-01-01 00:00:00
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journal_title:Research in developmental disabilities
pub_type: 杂志文章
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更新日期:2015-08-01 00:00:00
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journal_title:Research in developmental disabilities
pub_type: 杂志文章
doi:10.1016/j.ridd.2009.05.004
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更新日期:2016-04-01 00:00:00
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pub_type: 临床试验,杂志文章
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journal_title:Research in developmental disabilities
pub_type: 杂志文章
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更新日期:2015-02-01 00:00:00
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journal_title:Research in developmental disabilities
pub_type: 杂志文章
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