Optimal cyclosporine plasma levels decline with time of therapy.

Abstract:

:To avoid nephrotoxicity and hepatotoxicity the CsA-PL should be kept at less than 500 ng/mL during the first month after transplantation and less than 200 ng/mL after four months. After ten months most patients in this study had a CsA-PL of less than 150 ng/mL and many had levels of less than 50 ng/mL with an apparently good immunosuppressive effect. Rejections showed no correlation with high or low CsA-PL. Continuous monitoring of CsA-PL is recommended for the management of renal allograft recipients.

journal_name

Transplant Proc

authors

Klintmalm G,Säwe J,von Bahr C,Ringdén O,Lundgren G,Wilczek H,Tydén G,Groth CG

subject

Has Abstract

pub_date

1984-10-01 00:00:00

pages

1208-11

issue

5

eissn

0041-1345

issn

1873-2623

journal_volume

16

pub_type

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