Abstract：
:Total incidence and outcome of cancer in all renal allograft recipients in one geographic area are known: 126 (7%) of 1884 patients developed cancer during an 11-year period. Proportions with cancer 1 and 5 years following successful transplantation were 11% and 24%, respectively. Numbers, proportion of malignancies, and average time of diagnosis post transplantation were as follows: reticulum cell sarcoma (RCS) 15 (11%), 18 months; adenocarcinoma 8 (6%), 21/2 years; cancer of cervix 6 (5%), 41/2 years; leukemia 2 (2%), 5 years. All were highly malignant except cancer of the cervix, 2 localized forms of RCS, and 4 cases of cerebral RCS that responded to radiotherapy. Skin malignancy (SM) occurred in 97 patients (77% of cancers). The frequency increased with time, and after 4 years 18% of survivors had this cancer. In patients with SM 17% had multiple lesions when first diagnosed; further cancers or recurrences of the same type developed in 23%; another form of SM developed in 15%; metastases occurred 9 times (9%), 4 fatally. Six (6%) patients with SM developed other forms of malignancy, as compared to 33 (2%) of 1786 patients without SM. Ooulook for patients with SM with regard to survival and graft function was greatly improved at 5 years, as compared to that for patients without SM. Thereafter the outlook for patients with SM worsened rapidly because of additional effects of malignancy.
journal_name
Transplant Procjournal_title
Transplantation proceedingsauthors
Sheil AGsubject
Has Abstractpub_date
1977-03-01 00:00:00pages
1133-6issue
1eissn
0041-1345issn
1873-2623journal_volume
9pub_type
杂志文章abstract：BACKGROUND:The aim of this study was to examine which demographic and comorbidity factors affected the activation of patients with end-stage renal disease on the national kidney transplantation waiting list. METHODS:This was a prospective cohort study across 13 transplantation centers in the United Kingdom from Octobe...
journal_title：Transplantation proceedings
pub_type： 杂志文章,多中心研究
doi：10.1016/j.transproceed.2013.03.033
更新日期：2013-07-01 00:00:00
abstract：:During orthotopic liver transplantation (OLT), various situations may occur in which biliary reconstruction is neither technically feasible nor recommended. One bridge to a delayed anastomosis can be an external biliary fistula (EBF). This procedure allows the surgeon to execute hemostatic maneuvers, such as abdominal...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：10.1016/j.transproceed.2009.03.026
更新日期：2009-05-01 00:00:00
abstract：INTRODUCTION:Biliary complications after orthotopic liver transplantation (OLT) are the principal cause of morbidity and graft dysfunction, ranging in incidence from 5.8% to 30% of cases. Biliary strictures are the most frequent type of late complication. The aim of this study was to evaluate the role of magnetic reson...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：10.1016/j.transproceed.2011.03.016
更新日期：2011-05-01 00:00:00
abstract：BACKGROUND:One of the most important mechanisms of allograft rejection is the production of donor-specific antibodies (DSA). Anti-major histocompatibility complex class-I chain-related antigen A (MICA) and anti-glutathione S transferase-T1 (GSTT1) antibodies cause graft dysfunction and reduce graft survival. The aim of...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：10.1016/j.transproceed.2013.02.097
更新日期：2013-04-01 00:00:00
abstract：INTRODUCTION:Antithymocyte globulin (ATG)-Fresenius (Neovii-Biotech, Graefelfing, Germany), a highly purified rabbit polyclonal antihuman T-lymphocyte immunoglobulin resulting from immunization of rabbits with the Jurkat T-lymphoblast cell line, is currently used for the prevention of acute rejection in patients receiv...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：10.1016/j.transproceed.2014.07.016
更新日期：2014-11-01 00:00:00
abstract：OBJECTIVE:To evaluate relevant arterial, hepatic, and portal venous anatomy using multidetector computed tomography (CT) angiography in potential living liver donors at a single liver transplantation center in China. METHODS:One hundred two consecutive potential liver donors underwent CT angiography in the arterial, p...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：10.1016/j.transproceed.2008.08.031
更新日期：2008-10-01 00:00:00
abstract：BACKGROUND:Ascites is the most common complication of cirrhosis and indicates that the disease is at an advanced stage. In cirrhotic patients with refractory ascites, treatment is based on repeat paracentesis. The objective of this study is to evaluate the cost of paracentesis in cirrhotic patients and to determine the...
journal_title：Transplantation proceedings
pub_type： 临床试验,杂志文章
doi：10.1016/j.transproceed.2014.05.017
更新日期：2014-07-01 00:00:00
abstract：:The aim of the study was to assess impaired tubular phosphate reabsorption and renal function among patients on cyclosporine- or tacrolimus-based immunosuppression for 2 years after kidney transplantation. Among 60 cadaveric kidney allograft recipients observed for 48 months, 40 received cyclosporine, azathioprine, an...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：10.1016/j.transproceed.2005.12.083
更新日期：2006-01-01 00:00:00
abstract：:It is well known that interferon-gamma (IFN-gamma) not only plays a critical role in antigen-dependent but also in antigen-independent tissue injury; however, it is not clear how tolerance induction affects the actions of IFN-gamma in the transplant setting. To address this question, we compared the effects of IFN-gam...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：10.1016/j.transproceed.2006.10.119
更新日期：2006-12-01 00:00:00
abstract：:PAP of harvested livers is routinely used to minimize parenchymal anoxia during storage. PP is compared with PAP to evaluate the relative reliability of PAP. Sixty female Landrace pigs were used for 30 OLTs. Group 1 livers underwent PP, whereas group 2 livers were treated with PAP. The cold ischemic time was less than...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：
更新日期：1988-02-01 00:00:00
abstract：:In adult-to-adult living liver transplantation, small-for-size graft syndrome sometimes occurs. The relationship between the hemodynamic changes and histologic findings has not been studied in patients with failure of small-for-size grafts. We analyzed the relationship between the postoperative hemodynamic changes and...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：10.1016/j.transproceed.2004.09.036
更新日期：2004-11-01 00:00:00
abstract：:An account is given of the 6- to 12-month survival, and causes of failure in 110 consecutive patients who underwent primary liver transplantation under treatment from the outset with FK 506 and steroids. The patient survival is 92.7%, and the first graft survival is 87.3%. At a very high frequency, the patients achiev...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：
更新日期：1991-02-01 00:00:00
abstract：INTRODUCTION:Orthotopic liver transplantation (OLT) is a rational therapeutic option for early-stage hepatocellular carcinoma (HCC) providing a potential cure and improving survival. METHODS:This retrospective study of a longitudinal cohort used an electronic database collected prospectively from September 1997 to May...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：10.1016/j.transproceed.2011.02.032
更新日期：2011-05-01 00:00:00
abstract：BACKGROUND:The Model for End-Stage Liver Disease (MELD) score has been validated to predict the mortality rate of patients with various chronic liver diseases on the waiting list for liver transplantation (LT). The aim of this study was to assess the value of the postoperative MELD scoring system as an early postoperat...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：10.1016/j.transproceed.2013.09.034
更新日期：2014-01-01 00:00:00
abstract：:Heart transplantation-induced dyslipidemia is a recognized risk factor for cardiac allograft vasculopathy that affects survival prognosis. Beyond increased lipids, low-density lipoprotein (LDL) size and systemic factors, including glucose intolerance, oxidative stress, and inflammation, must be taken into account as c...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：10.1016/j.transproceed.2005.05.010
更新日期：2005-07-01 00:00:00
abstract：OBJECTIVE:Our goal was to analyze the morbidity of organic erectile dysfunction (ED) in kidney-transplant patients and to evaluate the efficacy and reliability of sildenafil citrate treatment. METHOD:Sixty-five ED patients with normal graft function for 3 to 12 months after kidney transplantation were involved in our ...
journal_title：Transplantation proceedings
pub_type： 临床试验,杂志文章
doi：10.1016/j.transproceed.2005.03.026
更新日期：2005-06-01 00:00:00
abstract：:Enteric-coated mycophenolate sodium (EC-MPS) is designed to reduce mycophenolate acid (MPA)-related upper gastrointestinal (GI) adverse events (AEs). A multicenter, open-label, Latin American study in stable renal transplant patients is ongoing to assess the safety of the conversion from mycophenolate mofetil (MMF) to...
journal_title：Transplantation proceedings
pub_type： 临床试验,杂志文章,多中心研究
doi：10.1016/j.transproceed.2004.07.031
更新日期：2004-07-01 00:00:00
abstract：BACKGROUND:Acute-on-chronic liver failure (ACLF) is defined as an acute deterioration of chronic liver disease. Intrasplenic hepatocyte transplantation is increasingly recognized as a treatment for liver failure and genetic metabolic liver diseases. We describe our experience of intrasplenic hepatocyte transplantation ...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：10.1016/j.transproceed.2013.10.042
更新日期：2014-01-01 00:00:00
abstract：BACKGROUND:Liver transplantation is indicated at the end stage of chronic liver failure, and severity of disease will determine the precocity of this happening. At this stage, the presence of chronic dyspnea is one of several manifestations of progression of the disease, which leads the patient to inactivity. A rehabil...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：10.1016/j.transproceed.2016.06.027
更新日期：2016-09-01 00:00:00
abstract：INTRODUCTION:Few groups have studied the impact of pretransplant transarterial chemoembolization (TACE) in the outcomes of liver transplant recipients with hepatocellular carcinoma (HCC). We verified whether response to TACE in HCC candidates impacts post-transplant disease-free survival. METHODS:This a single center ...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：10.1016/j.transproceed.2014.05.039
更新日期：2014-07-01 00:00:00
abstract：BACKGROUND:Endothelial dysfunction (ED) is a common, early abnormality that predisposes patients to develop atherosclerosis and cardiovascular events; inflammation is associated with atherosclerosis and malnutrition. Patients with failed transplants are usually complicated by inflammation; however, ED in this group of ...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：10.1016/j.transproceed.2009.06.200
更新日期：2009-11-01 00:00:00
abstract：:Cytomegalovirus (CMV) end-organ disease is a serious, frequent complication after allogenic stem cell transplantation (Allo-SCT). There are two prevention strategies: universal prophylaxis and preemptive therapy. Preemptive therapy is administered based on the results of sensitive techniques that detect the viral infe...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：10.1016/j.transproceed.2010.05.050
更新日期：2010-10-01 00:00:00
abstract：:Downstaging treatment of hepatocellular carcinoma (HCC) prior to liver transplant (LT) is an accepted strategy to meet the Milan criteria. However, after transplant surgery, a reality is noted that the number or/and the size of some HCCs measured from the liver explants is different from that measured from the pre-LT ...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：10.1016/j.transproceed.2019.03.020
更新日期：2019-06-01 00:00:00
abstract：OBJECTIVE:The aim of this study was to evaluate the postoperative changes in hemodynamics and biochemical indices in pediatric recipients of live-donor liver transplants (LDLT). METHODS:Hemodynamics and biochemical indices (coagulation function, electrolytes, kidney function, liver function, and blood analysis) were m...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：10.1016/j.transproceed.2013.04.013
更新日期：2013-11-01 00:00:00
abstract：BACKGROUND:Chronic rejection (CR) in terms of bronchiolitis obliterans (BO) and vascular sclerosis (VS) still represents the major obstacle for pulmonary graft survival in the medium and long term course after lung transplantation (LTX). Aside from nonspecific stimuli, early acute rejection (AR) seems to be causative e...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：10.1016/j.transproceed.2012.03.066
更新日期：2013-03-01 00:00:00
abstract：:Cyclosporine absorption has been key to obtaining adequate results in immunosuppressive regimens. Since 2005, we have used a different monitoring program for Cyclosporine among pediatric liver transplant recipients namely, two hours post dosing concentrations (O(2)). This study of 128 patients included 50.8% males and...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：10.1016/j.transproceed.2009.11.016
更新日期：2010-01-01 00:00:00
abstract：:This article seeks to standardize an experimental model of liver ischemia-reperfusion in rats following hemorrhagic shock modulated by N-acetylcysteine (NAC). Twenty-seven adult Wistar rats were randomized into three groups: the HS-IR-Garm underwent hemorrhagic shock with selective hepatic ischemia followed by reperfu...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：10.1016/j.transproceed.2004.03.047
更新日期：2004-05-01 00:00:00
abstract：:In renal ischemia/reperfusion (I/R) injury endothelial cells are a main target. The disturbance of endothelial cell physiology leads to endothelial swelling and narrowing of the blood vessel lumen. We attribute this effect to impairment of endothelial cell nitric oxide synthase (NOS). NO is significantly reduced in th...
journal_title：Transplantation proceedings
pub_type： 杂志文章,评审
doi：10.1016/j.transproceed.2006.01.059
更新日期：2006-04-01 00:00:00
abstract：BACKGROUND AND AIM:The clearance of plasma cytokines by means of albumin dialysis (MARS) has been demonstrated in various studies involving patients affected by either acute liver failure (ALF) or acute on chronic liver failure. The aim of the study was to measure the plasma levels of TNF-alpha, IL-6, and IL-1beta in p...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：10.1016/j.transproceed.2005.06.040
更新日期：2005-07-01 00:00:00
abstract：:Nontuberculous mycobacteria are ubiquitous and infrequently cause disease in humans, most commonly in immunocompromised hosts. One type of nontuberculous mycobacteria is Mycobacterium abscessus. This rapidly growing mycobacterium is a soil or water saprophyte. It was previously classified as a subspecies of Mycobacter...
journal_title：Transplantation proceedings
pub_type： 杂志文章,评审
doi：10.1016/j.transproceed.2006.02.126
更新日期：2006-06-01 00:00:00
