Diagnosis of renal allograft rejection and acute tubular necrosis by 99mTc-mononuclear leukocyte imaging.

Abstract:

:One hundred kidney transplant recipients were evaluated on the first and fifth days after transplantation by Tc-99m mononuclear cell scintigraphy. We have developed a quantitative method to diagnose rejection and acute tubular necrosis (ATN) by comparing regions of interest drawn on allograft scintigraphs at different times after endovenous administration of the labeled cells. We suggest that the use of Tc-99m-WBC may be useful for the early diagnosis of rejection and the differential diagnosis of ATN.

journal_name

Transplant Proc

authors

Lopes de Souza SA,Barbosa da Fonseca LM,Torres Gonçalves R,Salomão Pontes D,Holzer TJ,Proença Martins FP,Gutfilen B

doi

10.1016/j.transproceed.2004.11.100

subject

Has Abstract

pub_date

2004-12-01 00:00:00

pages

2997-3001

issue

10

eissn

0041-1345

issn

1873-2623

pii

S0041-1345(04)01411-3

journal_volume

36

pub_type

杂志文章
  • The effects of C-reactive protein, interleukin-6, and tumor necrosis factor-alpha in rat allograft adventitial inflammation and allograft arteriosclerosis.

    abstract::This study was designed to investigate the role of C-reactive protein (CRP), interleukin-6 (IL-6), and tumor necrosis factor-alpha (TNF-alpha) during allograft adventitial inflammation and arteriosclerosis. Lewis rats were used as donors and Wistar rats as recipients for the experimental groups, while both donors and ...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2009.06.190

    authors: Sun H,Lu X,Wu S,Sun W

    更新日期:2009-11-01 00:00:00

  • Superoxide anion as a marker of ischemia-reperfusion injury of the transplanted kidney.

    abstract::Reactive oxygen species (ROS) are considered to be important factors involved in the pathophysiology of renal ischemia-reperfusion injury. ROS-induced alterations of proteins, carbohydrates, DNA, and lipid membranes lead to cell and organ dysfunction. Several antioxidant defense mechanisms exist to prevent or limit ox...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2005.12.084

    authors: Masztalerz M,Włodarczyk Z,Czuczejko J,Słupski M,Kedziora J

    更新日期:2006-01-01 00:00:00

  • Specific tolerance to canine renal allografts following treatment with fractionated bone marrow and antilymphocyte serum.

    abstract::These results suggest (1) that ALS + BM fractions can be used to promote tolerance in long-term graft survivors; (2) that the presence of apparent BM cells of donor origin in the allograft in normally functioning kidneys may be related to the mechanism of allograft prolongation, and (3) that some promise of possible s...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:

    authors: Hartner WC,De Fazio SR,Markees TG,Maki T,Monaco AP,Gozzo JJ

    更新日期:1987-02-01 00:00:00

  • Role of regulated upon activation normal T-cell expressed and secreted in a model of retransplantation acute rejection mediated by alloreactive memory CD4+ T cells.

    abstract:BACKGROUND:It is unknown what role Regulated Upon Activation Normal T-Cell Exposed and Secreted may play in retransplantation or T-cell memory-transfer models. The experiment observed the influence of the chemokine RANTES in a mouse model of acute cardiac allograft rejection induced by adoptive transfer of alloreactive...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2012.11.005

    authors: Zhou X,Shan Z,Liang H,Lin Z,Qiu S,Kuang F,Zhuang J,Qi Z

    更新日期:2013-03-01 00:00:00

  • Liver Transplantation Outcomes Using Grafts From Donors Older Than the Age of 80 Years.

    abstract::We performed a retrospective cohort study between 2002 and 2014 to compare liver transplantation outcomes between recipients of grafts from donors older than and younger than the age of 80 years. Numerical variables were compared with the Student t test when their distribution was normal and the Mann-Whitney test when...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2015.10.004

    authors: Rabelo AV,Alvarez MJ,Méndez CS,Villegas MT,MGraneroa K,Becerra A,Dominguez M,Raya AM,Exposito M,Suárez YF

    更新日期:2015-11-01 00:00:00

  • Ischemic preconditioning improves rat kidney graft function after severe ischemia/reperfusion injury.

    abstract:UNLABELLED:Ischemic preconditioning (IP) has been shown to ameliorate renal ischemia reperfusion injury. Using a rat kidney transplantation model we determined if IP improves graft function after prolonged cold storage. MATERIALS AND METHODS:Syngeneic rat kidneys were divided into two groups. Prior to 42 hours of cold...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2004.12.274

    authors: Fuller TF,Freise CE,Feng S,Niemann CU

    更新日期:2005-01-01 00:00:00

  • Imbalance of metallaproteinase/tissue inhibitors of metalloproteinase system in renal transplant recipients with chronic allograft injury.

    abstract:INTRODUCTION:Nowadays, renal allografts continue to be lost at the rate of 2% to 4% per year beyond the first year after transplantation due to chronic allograft injury. Excessive accumulation of extracellular matrix results from overproduction and/or defective degradation by proteolytic enzymes, among which metallopro...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2011.08.012

    authors: Mazanowska O,Kamińska D,Krajewska M,Zabińska M,Kopeć W,Boratyńska M,Chudoba P,Patrzalek D,Klinger M

    更新日期:2011-10-01 00:00:00

  • Hepatitis C virus recurrence after liver transplantation: influence of immunosuppressive regimens on viral load and liver histology.

    abstract::Cyclosporine has recently been reported to produce in vitro suppression of hepatitis C virus replication driven by blockade of cyclophilins, an effect not shown for tacrolimus. However, the clinical consequence of this in vitro finding have not been well studied in vivo. We compared viral load and fibrosis in transpla...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2006.08.055

    authors: Oton E,Barcena R,Castillo M,Barreales M,Blesa C,Moreno-Planas JM,Barrios C,Garrido A,Cuervas V

    更新日期:2006-10-01 00:00:00

  • Male sexual function in patients receiving different types of renal replacement therapy.

    abstract:BACKGROUND:Patients with end-stage renal disease (ESRD) experience erectile dysfunction (ED). Although it is a benign disorder, ED is related to physical and psychosocial health, and it has a significant impact on the quality of life (QOL). The objective of the present study was to investigate the effects of different ...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2013.09.025

    authors: Yavuz D,Acar FN,Yavuz R,Canoz MB,Altunoglu A,Sezer S,Durukan E

    更新日期:2013-01-01 00:00:00

  • Carbapenem-resistant Acinetobacter baumannii Bacteremia in Liver Transplant Recipients.

    abstract:BACKGROUND:Acinetobacter baumannii has become an increasingly important nosocomial pathogen. Carbapenem is the preferred drug of choice for treatment of multidrug-resistant gram-negative bacilli, but carbapenem-resistant A baumannii (CRAB) has now emerged. The aim of this study was to determine the incidence, outcomes,...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2018.01.043

    authors: Kim YJ,Kim SI,Lee YD,Choi HJ,Choi JY,Yoon SK,You YK,Kim DG

    更新日期:2018-05-01 00:00:00

  • Utility of Oral Anticoagulants as Prophylaxis of Recurrent Portal Thrombosis after Liver Transplantation.

    abstract:INTRODUCTION:Portal vein thrombosis (PVT) is a relatively common finding in patients undergoing liver transplantation. Although the recommendation to prevent its recurrence is anticoagulation for a duration of 3 to 6 months, this is controversial. AIM:The aim of our study was to determine the efficacy of oral anticoag...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2018.07.014

    authors: Sanchez-Ocaña R,Tejedor-Tejada J,Cimavilla-Roman M,de Benito-Sanz M,Asensio-Diaz E,Barrera-Rebollo A,Perez-Saborido B,Garcia-Pajares F,Almohalla-Alvarez C,Sanchez-Antolin G

    更新日期:2019-01-01 00:00:00

  • Evaluation of the efficacy and safety of the conversion from a calcineurin inhibitor to an everolimus-based therapy in maintenance renal transplant patients.

    abstract::Everolimus has recently been introduced into clinical practice with promising perspectives due to its efficacy, lack of nephrotoxicity, and antitumor effects. Experience in clinical trials associated with low-dose cyclosporine showed good results, but there is almost no experience in calcineurin inhibitor (CNI) elimin...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2007.06.030

    authors: Sánchez Fructuoso A,Ruiz San Millán JC,Calvo N,Rodrigo E,Moreno MA,Cotorruelo J,Conesa J,Gómez-Alamillo C,Arias M,Barrientos A

    更新日期:2007-09-01 00:00:00

  • Chronic intestinal pseudo-obstruction related to viral infections.

    abstract::Chronic intestinal pseudo-obstruction (CIPO), one of the most severe gastrointestinal motility disorders, is a condition characterized by a clinical picture mimicking small bowel occlusion with related symptoms and signs in the absence of demonstrable mechanical obstruction. Analysis of full-thickness biopsy samples m...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2009.12.014

    authors: De Giorgio R,Ricciardiello L,Naponelli V,Selgrad M,Piazzi G,Felicani C,Serra M,Fronzoni L,Antonucci A,Cogliandro RF,Barbara G,Corinaldesi R,Tonini M,Knowles CH,Stanghellini V

    更新日期:2010-01-01 00:00:00

  • Intestinal transplantation: advances in immunosuppression and surgical techniques.

    abstract::Campath-1H is being used as induction immunosuppression for intestinal/multivisceral transplantation. Patient and graft survival in this preliminary experience is similar to previous studies but there has been a significant decrease in the incidence and severity of acute rejections without increase of opportunistic in...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/s0041-1345(03)00734-6

    authors: Tzakis AG,Tryphonopoulos P,Kato T,Nishida S,Levi DM,Nery JR,Madariaga J,De Faria W,Mittal N,Thompson JF,Ruiz P

    更新日期:2003-08-01 00:00:00

  • Split liver transplantation in Shiraz Transplant Center.

    abstract:BACKGROUND:Cadaveric organ splitting emerged from an improved understanding of the surgical anatomy of the liver as a possible mechanism to expand the organ pool. In this study, we have reported our first series of split liver transplantations (SLT). MATERIALS AND METHODS:From June 2006 to June 2008, we performed 17 p...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2009.07.052

    authors: Bahador A,Salahi H,Nikeghbalian S,Dehghani SM,Kakaei F,Sabet B,Kazemi K,Rajaei E,Gholami S,Malek-Hosseini SA

    更新日期:2009-09-01 00:00:00

  • Change of hepatitis B virus DNA and covalently closed circular DNA status in liver graft after liver transplantation.

    abstract::Recurrence of hepatitis B virus (HBV) occurs despite prophylaxis, and covalently closed circular DNA (cccDNA) is thought to play a role owing to its resistance to prophylactic agents used. The aim of this study was to evaluate the changes of HBV DNA and cccDNA within the liver graft during liver transplantation (LT). ...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2013.11.081

    authors: Kwon CH,Suh KS,Shin JO,Kim SJ,Joh JW

    更新日期:2014-04-01 00:00:00

  • Impact of Splenectomy Just Before Partial Orthotopic Liver Transplantation Using Small-for-Size Graft in Rats.

    abstract:BACKGROUND:Portal hypertension is a serious obstacle of partial orthotopic liver transplantation (POLT) with the use of small-for-size liver graft. Several therapeutic strategies including surgical innovations and pharmacological agents to reduce the portal hypertension have been developed. Splenectomy (SP) on POLT is ...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2016.02.041

    authors: Kuriyama N,Iizawa Y,Kato H,Murata Y,Tanemura A,Azumi Y,Kishiwada M,Mizuno S,Usui M,Sakurai H,Isaji S

    更新日期:2016-05-01 00:00:00

  • Left Hepatic Lobectomy in the Living Donor-Comparison Between Open vs Laparoscopic Surgery.

    abstract::Laparoscopic hepatic surgery dramatically changed surgical practice in the last decades, improving outcomes in correctly selected patients. The reduction of postoperative pain, lower rate of complication, early return to work activities, and better esthetic result have been well described in several studies. The succe...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2019.03.003

    authors: Vieira V,Pacheco L,Demetrio L,Balbi E,Bellinha T,Toledo R,Auler L,Pestana D,Schul M

    更新日期:2019-06-01 00:00:00

  • Spousal versus living unrelated renal transplantation: a retrospective analysis of allograft outcomes.

    abstract:OBJECTIVE:To compare the outcomes of spousal and living unrelated donor (LUD) allografts. PATIENTS AND METHODS:The 378 ABO-compatible living and cadaveric kidney transplantations between February 2005 and August 2010 included 25 wife-to-husband (group 1), 15 husband-to-wife (group 2), and 20 LUD cases (group 3). Donor...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2012.05.069

    authors: Solak I,Sezer TO,Toz H,Tatar E,Isayev C,Firat O,Hoscoskun C

    更新日期:2012-07-01 00:00:00

  • New strategies of cyclosporine monitoring in heart transplantation: initial results.

    abstract::The aim of this study was to evaluate cyclosporine (CyA) absorption profiles in heart transplantation to establish the most adequate monitoring strategy and determine the optimal therapeutic range for AUC(0-4) or C2 levels. A total of 22 full pharmacokinetic studies were performed at steady-state in 22 adult heart tra...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/s0041-1345(03)00657-2

    authors: Arizón del Prado JM,Aumente Rubio MD,Cárdenas Aranzana M,López Malo de Molina MD,Segura Saint-Gerons J,López Granados A,Rodríguez Esteban E,Ruiz Ortiz M,Romo Peñas E,Muñoz Carvajal I,González Rodríguez JR,Segura Saint-Gerons C,Va

    更新日期:2003-08-01 00:00:00

  • Investigation of the Causes and Risk Factors of Previous End-Stage Renal Disease in Kidney Transplant Recipients.

    abstract:BACKGROUND:Chronic kidney disease (CKD) is a pathophysiological process with many etiologic causes, often leading to end-stage renal disease (ESRD). The distribution of the causes that lead to ESRD varies by country, race, and sex. Renal failure may be prevented by determining these differences and reducing the risk fa...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2019.11.019

    authors: Aksoy N,Şelimen D

    更新日期:2020-01-01 00:00:00

  • Prevalence of hepatitis B, hepatitis delta, and human immunodeficiency virus infections in Omani patients with renal diseases.

    abstract::Patients treated at the Royal Hospital in Oman during January-June 1991 were divided in 3 groups. The 1st group included 103 patients (49 males, 54 females, with a mean of 39 years) who attended the Nephrology Clinic and none of whom were on dialysis. In the 2nd group there were 102 patients (46 males, 56 females, w...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:

    authors: Aghanashinikar PN,al-Dhahry SH,al-Marhuby HA,Buhl MR,Daar AS,Al-Hasani MK

    更新日期:1992-10-01 00:00:00

  • Experimental model of isolated lung perfusion in rats: first Brazilian experience using the IL-2 isolated perfused rat or guinea pig lung system.

    abstract:INTRODUCTION:Lung transplantation has become the mainstay therapy for patients with end-stage lung disease refractory to medical management. However, the number of patients listed for lung transplantation largely exceeds available donors. The study of lung preservation requires accurate, cost-effective small animal mod...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2010.01.016

    authors: Pêgo-Fernandes PM,Werebe E,Cardoso PF,Pazetti R,de Oliveira KA,Soares PR,Jatene FB

    更新日期:2010-03-01 00:00:00

  • Gene transfer using recombinant simian virus 40 viral vectors into mice bone marrow progenitor cells depressed the immunogenicity of keratinocyte stem cells.

    abstract::Hematopoietic stem cell (HSC) gene transfer has been attempted almost entirely ex vivo and has been limited by loss of self-renewal capacity and transplantation-related defects in homing and engraftment. Herein we have attempted to overcome these limitations by injecting vectors directly into the bone marrow (BM) to t...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2008.06.090

    authors: Li W,Xu T,Wang JF,Wu XF,Li M,Lu PY

    更新日期:2008-12-01 00:00:00

  • Simultaneous Deceased Donor Liver and Kidney Transplantation in a Human Immunodeficiency Virus/Hepatitis C Virus -Coinfected Patient With Hemophilia in Japan: A Case Report.

    abstract::The authors describe the first case of simultaneous liver and kidney transplantation (SLK) in a human immunodeficiency virus (HIV)/hepatitis C virus (HCV)-coinfected patient with severe hemophilia in Japan, and it could be second case in the world. The patient was a 61-year-old Japanese man with HCV cirrhosis complica...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2020.05.005

    authors: Eguchi S,Hidaka M,Natsuda K,Hara T,Kugiyama T,Hamada T,Tanaka T,Ono S,Adachi T,Kanetaka K,Soyama A,Mochizuki Y,Sakai H

    更新日期:2020-11-01 00:00:00

  • Elevated Monocyte Count and Loss of Renal Function in Renal Transplant Patients.

    abstract:BACKGROUND:Rejection is an important factor affecting graft function in renal transplant patients. Development of acute rejection even after induction treatment suggests that humoral and cellular immune systems are not the only mechanisms responsible for this event. The innate immune system can play roles in rejection....

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2020.02.176

    authors: Buberci R,Paydas S

    更新日期:2020-12-01 00:00:00

  • Relationship Between Satisfaction With Social Support and Self-Efficacy and the Occurrence of Depressive Symptoms and Stress in Heart Transplant Recipients.

    abstract::Heart transplantation is a recognized and effective therapeutic method for treating end-stage circulatory failure. Physical factors and psychosocial issues among heart transplant recipients have been addressed in an increasing number of studies. According to the transactional model of stress, social support is one of ...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2018.02.156

    authors: Milaniak I,Wilczek-Rużyczka E,Wierzbicki K,Piątek J,Kapelak B,Przybyłowski P

    更新日期:2018-09-01 00:00:00

  • Relationships Between Metabolic Syndrome, Microalbuminuria, and C-Reactive Protein in Turkish Kidney Transplant Recipients.

    abstract:AIM:The aims of this study were to report the prevalence of metabolic syndrome (MS) in a cohort of Turkish kidney transplant recipients and to define the relationships between MS, microalbuminuria and C-reactive protein (CRP), which are cardiovascular risk factors, in kidney transplant setting. METHODS:This cross sect...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2015.04.037

    authors: Sipahioglu MH,Unal A,Yazgac H,Tunca O,Arikan T,Kocyigit I,Tokgoz B,Oymak O

    更新日期:2015-06-01 00:00:00

  • Use of Nonvascularized Abdominal Rectus Fascia After Liver, Small Bowel, and Multiorgan Transplantation: Long-Term Follow-up of a Single-Center Series.

    abstract:BACKGROUND:The abdominal wall may be severely compromised in the vast majority of intestinal and multiorgan transplant candidates, and sometimes as a consequence of complex liver transplantation. Multiple options have been described to overcome this problem, varying from component separation to the extreme need of perf...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2017.05.012

    authors: Farinelli PA,Rubio JS,Padín JM,Rumbo C,Solar H,Ramisch D,Gondolesi GE

    更新日期:2017-10-01 00:00:00

  • Two-hour post-dose cyclosporine levels in renal transplantation in Argentina: a cost-effective strategy for reducing acute rejection.

    abstract:UNLABELLED:Monitoring of cyclosporine (microemulsion CsA) at 2 hours post-dose (C2), a measure of absorption and exposure, appears superior to trough (C0) monitoring for prediction of rejection risk. The purpose of this study was to determine whether C2 was cost-effective compared to C0 in Argentina. METHODS:A predict...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2004.12.188

    authors: Balshaw R,Machnicki G,Carreño CA,Toselli L,Otero A,Keown PA

    更新日期:2005-03-01 00:00:00