Effect of hydroxyethyl starch on postoperative kidney function in patients having noncardiac surgery.

abstract：:Data regarding left ventricular function suggest that the extent of shortening may differ between regions. This study was undertaken to determine the effects of negative inotropic drugs used during anesthesia on different areas of the left ventricle. Forty mongrel dogs were anesthetized and instrumented for measuremen...

journal_title：Anesthesiology

authors： Diedericks J,Leone BJ,Foëx P

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:Both pain and the pharmacologic management of pain can cause the undesirable effect of sleep disruption. One goal of basic and clinical neuroscience is to facilitate rational drug development by identifying the brain regions and neurochemical modulators of sleep and pain. Adenosine is thought to be an endoge...

journal_title：Anesthesiology

authors： Tanase D,Baghdoyan HA,Lydic R

更新日期：2002-12-01 00:00:00

abstract：BACKGROUND:When performing experiments at room temperature with volatile general anesthetics and in vitro mammalian preparations (such as isolated neurons), the question arises as to which concentrations of anesthetics are "clinically relevant." Different choices can lead to different interpretations of the anesthetic ...

journal_title：Anesthesiology

authors： Franks NP,Lieb WR

更新日期：1996-03-01 00:00:00

abstract：BACKGROUND:In cardiac patients, pulmonary capillary wedge pressure (PCWP) is estimated using color M-mode Doppler study of left ventricular filling and Doppler tissue imaging. The goal of this study was to assess whether echocardiography accurately estimates PCWP in critically ill patients. METHODS:Sixty ventilated pa...

journal_title：Anesthesiology

authors： Bouhemad B,Nicolas-Robin A,Benois A,Lemaire S,Goarin JP,Rouby JJ

更新日期：2003-05-01 00:00:00

abstract：BACKGROUND:Halothane and isoflurane have been reported to suppress the contraction of vascular smooth muscle, although the exact mechanism has not been explained fully. This study examined the effect of halothane and isoflurane on cytosolic calcium ion (Ca2+) concentrations ([Ca2+]cyt), which was measured simultaneousl...

journal_title：Anesthesiology

authors： Tsuchida H,Namba H,Yamakage M,Fujita S,Notsuki E,Namiki A

更新日期：1993-03-01 00:00:00

abstract：:The authors investigated the value of high-dose thiopental (TH) therapy after 16-min complete global brain ischemia (GBI) in three groups of pigtailed monkeys, using a neck cuff model of GBI with 96 h intensive care postischemia (PI). Control group (n18): Normotension was restored within 2 min PI; paralysis/controlled...

journal_title：Anesthesiology

authors： Gisvold SE,Safar P,Hendrickx HH,Rao G,Moossy J,Alexander H

更新日期：1984-02-01 00:00:00

abstract：BACKGROUND:Drugs used for sedation in anesthesia and intensive care may cause pharyngeal dysfunction and increased risk for aspiration. In this study, the authors investigate the impact of sedative doses of morphine and midazolam on pharyngeal function during swallowing and coordination of breathing and swallowing. ME...

journal_title：Anesthesiology

authors： Hårdemark Cedborg AI,Sundman E,Bodén K,Hedström HW,Kuylenstierna R,Ekberg O,Eriksson LI

更新日期：2015-06-01 00:00:00

abstract：:Anesthetized, prone dogs were intubated with a double-lumen endobronchial tube, and the lungs were ventilated independently. Three methods of recording differential blood flow were compared during unilateral lung hypoxia: electromagnetic flow measurement, flow probes being fitted onto each main pulmonary artery after ...

journal_title：Anesthesiology

authors： Carlsson AJ,Hedenstierna G,Blomqvist H,Strandberg A

更新日期：1987-08-01 00:00:00

abstract：:To determine the correlation between the partial pressures of anesthetics in venous and arterial blood (Pv and Pa), and to assess whether this correlation was better than that between the partial pressure of anesthetic in alveolar gas (PA) and Pa, isoflurane (n = 4) or halothane (n = 4) was administered to eight patie...

journal_title：Anesthesiology

authors： Carpenter RL,Eger EI 2nd

更新日期：1989-04-01 00:00:00

abstract：BACKGROUND:Arginine vasopressin (AVP) is an important "stress" hormone that is known to play a key role in cardiovascular homeostasis of the systemic circulation. In contrast, the effects of AVP on the pulmonary circulation have not been extensively investigated, and the extent to which general anesthesia alters the pu...

journal_title：Anesthesiology

authors： Trempy GA,Nyhan DP,Murray PA

更新日期：1994-09-01 00:00:00

abstract：BACKGROUND:The effects of propofol, remifentanil, and their combination on phrenic nerve activity (PNA), resting heart rate (HR), mean arterial pressure (MAP), and nociceptive cardiovascular responses were studied in rabbits. METHODS:Basal anesthesia and constant blood gas tensions were maintained with alpha-chloralos...

journal_title：Anesthesiology

authors： Ma D,Chakrabarti MK,Whitwam JG

更新日期：1999-11-01 00:00:00

abstract：BACKGROUND:Cardiac surgery requiring the use of cardiopulmonary bypass is frequently complicated by coagulopathic bleeding that, largely due to the shortcomings of conventional coagulation tests, is difficult to manage. This study evaluated a novel transfusion algorithm that uses point-of-care coagulation testing. MET...

journal_title：Anesthesiology

authors： Karkouti K,McCluskey SA,Callum J,Freedman J,Selby R,Timoumi T,Roy D,Rao V

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:Propofol is widely used clinically for the induction and maintenance of anesthesia. Clinical case reports have shown that propofol has an antiatrial tachycardia/fibrillation effect; however, the related ionic mechanisms are not fully understood. The current study investigates the effects of propofol on human...

journal_title：Anesthesiology

authors： Yang L,Liu H,Sun HY,Li GR

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to determine whether combination of 1-5 microg intrathecal neostigmine would enhance analgesia from a fixed intrathecal dose of morphine. METHODS:A total of 60 patients undergoing gynecologic surgery were randomized to one of five groups. Patients received 15 mg bupivacaine plu...

journal_title：Anesthesiology

authors： Almeida RA,Lauretti GR,Mattos AL

更新日期：2003-02-01 00:00:00

abstract：BACKGROUND:Mask ventilation is an essential element of airway management that has rarely been studied as the primary outcome. The authors sought to determine the incidence and predictors of difficult and impossible mask ventilation. METHODS:A four-point scale to grade difficulty in performing mask ventilation (MV) is ...

journal_title：Anesthesiology

authors： Kheterpal S,Han R,Tremper KK,Shanks A,Tait AR,O'Reilly M,Ludwig TA

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND:The brain is assumed to be the site of anesthetic action, but anesthetics have effects elsewhere, such as the spinal cord. A preferentially anesthetized goat brain model was used to determine the importance of anesthetic action in the brain. METHODS:Six goats were anesthetized with isoflurane; after trachea...

journal_title：Anesthesiology

authors： Antognini JF,Schwartz K

更新日期：1993-12-01 00:00:00

abstract：:Sevoflurane, 1.4 per cent (MAC), was administered to groups of Fischer 344 rats for 10 hours, 4 hours, or 1 hour; additional rats received 0.5 per cent methoxyflurane for 3 hours or 1 hour. Urinary inorganic fluoride excretion of sevoflurane in vivo was a third to a fourth that of methoxyflurane. However, using hepati...

journal_title：Anesthesiology

authors： Cook TL,Beppu WJ,Hitt BA,Kosek JC,Mazze RI

更新日期：1975-07-01 00:00:00

abstract：BACKGROUND:General anesthetics reduce neuron loss following focal cerebral ischemia in rodents. The relative efficacy of this action among different anesthetics clinically used for neuroprotection is uncertain. In addition, it remains unclear how anesthetics compare to neuroprotection afforded by mild hypothermia. This...

journal_title：Anesthesiology

authors： Popovic R,Liniger R,Bickler PE

更新日期：2000-05-01 00:00:00

abstract：BACKGROUND:Despite decreasing cardiac events, perioperative beta-blockade also increases perioperative stroke and mortality. Major bleeding and/or hypotension are independently associated with these outcomes. To investigate the hypothesis that beta-blockade limits the cardiac reserve to compensate for acute surgical an...

journal_title：Anesthesiology

authors： Beattie WS,Wijeysundera DN,Karkouti K,McCluskey S,Tait G,Mitsakakis N,Hare GM

更新日期：2010-01-01 00:00:00

abstract：:The tape recorded EEGs of 127 patients anesthetized with large doses of opioids were retrospectively analyzed for evidence of opioid-induced seizures, and in particular, correlated with movements that occurred during induction and could be clinically interpreted as seizures. Bilateral EEG leads in patients receiving f...

journal_title：Anesthesiology

authors： Smith NT,Benthuysen JL,Bickford RG,Sanford TJ,Blasco T,Duke PC,Head N,Dec-Silver H

更新日期：1989-12-01 00:00:00

abstract：BACKGROUND:Studies on receptor knockout mice have so far shown that of the three alpha2-adrenoceptor subtypes, the alpha(2A) adrenoceptor has a major role in mediating the powerful central analgesia induced by synthetic alpha2-adrenoceptor agonists. However, because a knockout of the gene for the alpha(2A) adrenoceptor...

journal_title：Anesthesiology

authors： Mansikka H,Lähdesmäki J,Scheinin M,Pertovaara A

更新日期：2004-07-01 00:00:00

abstract：BACKGROUND:To interpret correctly the results from studies performed during surgery and anesthesia it is necessary to dissect the separate effect of the anesthetic technique itself. The purpose of this study was to investigate the metabolic effects of epidural blockade (T7-S1) with bupivacaine 0.25% after 12 h fasting ...

journal_title：Anesthesiology

authors： Schricker T,Klubien K,Wykes L,Carli F

更新日期：2000-01-01 00:00:00

abstract：:The effects of fentanyl or cardiovascular function, regional distribution of cardiac output, and the dose required for producing anesthesia were studied in ten previously catheterized, newborn lambs. In addition, the effects of fentanyl on cerebral blood flow and oxygen utilization were examined. Fentanyl in cumulativ...

journal_title：Anesthesiology

authors： Yaster M,Koehler RC,Traystman RJ

更新日期：1987-04-01 00:00:00

abstract：BACKGROUND:The number of pregnancy-related deaths and severe maternal complications continues to rise in the United States, and the quality of obstetrical care across U.S. hospitals is uneven. Providing hospitals with performance feedback may help reduce the rates of severe complications in mothers and their newborns. ...

journal_title：Anesthesiology

authors： Glance LG,Hasley S,Glantz JC,Stevens TP,Faden E,Kreso MA,Pyne SG,Wissler RN,Fichter J,Gloff MS,Dick AW

更新日期：2019-08-01 00:00:00

abstract：:Liver surgery is often accompanied by hepatic hypoperfusion and hypoxia, and it is controversial whether catecholamines increase hepatic blood flow and oxygen supply. The effects of 3 micrograms.kg-1.min-1 dobutamine on hepatic circulation and oxygen balance were examined in patients anesthetized with enflurane, nitro...

journal_title：Anesthesiology

authors： Kainuma M,Kimura N,Nonami T,Kurokawa T,Ito T,Nakashima K,Shimada Y

更新日期：1992-09-01 00:00:00

abstract：BACKGROUND:Although evidence of its effects is tentative, acupuncture has long been used in the treatment of multiple maladies. So far, it has not been possible to discriminate the effects of the venue from specific results of needling itself, thus physicians merely depend on patients' statements. The authors investiga...

journal_title：Anesthesiology

authors： Agarwal-Kozlowski K,Lange AC,Beck H

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND:It has been known that skeletal muscles show atrophic changes after prolonged sedation or general anesthesia. Whether these effects are due to anesthesia itself or disuse during anesthesia has not been fully clarified. Autophagy dysregulation has been implicated in muscle-wasting conditions. This study teste...

journal_title：Anesthesiology

authors： Kashiwagi A,Hosokawa S,Maeyama Y,Ueki R,Kaneki M,Martyn JA,Yasuhara S

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND:Although opioids remain the standard therapy for the treatment of postoperative pain, the prevalence of opioid misuse is rising. The extent to which opioid abuse or dependence affects readmission rates and healthcare utilization is not fully understood. It was hypothesized that surgical patients with a histo...

journal_title：Anesthesiology

authors： Gupta A,Nizamuddin J,Elmofty D,Nizamuddin SL,Tung A,Minhaj M,Mueller A,Apfelbaum J,Shahul S

更新日期：2018-05-01 00:00:00

abstract：:To determine whether neuronal firing is affected by anesthetics, the behavior of neurons in the mesencephalic reticular formation in response to repetitive somatosensory stimulation at 2/sec was studied during wakefulness and during nitrous oxide, halothane, and thiopental anesthesia in the cat. With clinical doses of...

journal_title：Anesthesiology

authors： Shimoji K,Matsuki M,Shimizu H,Maruyama Y,Aida S

更新日期：1977-10-01 00:00:00

abstract：:To determine the percentage of anesthetic metabolized and to assess the role of metabolism in the total elimination of inhaled anesthetics, the authors administered isoflurane, enflurane, halothane, and methoxyflurane simultaneously, for 2 h, to nine healthy patients. Total anesthetic uptake during the 2 h of washin a...

journal_title：Anesthesiology

authors： Carpenter RL,Eger EI 2nd,Johnson BH,Unadkat JD,Sheiner LB

更新日期：1986-08-01 00:00:00