Study of the natural history of immunoblastic lymphadenopathy and atypical immunoproliferative disorders.

abstract：:Environment may influence the development and prevention of cancer. Calcitriol has been associated with calcium homeostasis regulation. Many epidemiological, biochemical, and genetic studies have shown non-classic effects of vitamin D, such as its involvement in the progression of different cancers. Although vitamin D...

journal_title：Cancer investigation

authors： Picotto G,Liaudat AC,Bohl L,Tolosa de Talamoni N

更新日期：2012-10-01 00:00:00

abstract：:Increasing evidence indicates that disruption of circadian rhythms may be directly linked to cancer. Here we report that the expression levels of the core clock genes Per1 and Per3 measured by droplet digital polymerase chain reaction are significantly decreased in tumour tissue from 16 patients undergoing colorectal ...

journal_title：Cancer investigation

authors： Orhan T,Nielsen PB,Hviid TVF,Rosen AW,Gögenür I

更新日期：2019-01-01 00:00:00

abstract：:In this study, we evaluated SEA-H61D, a staphylococcal enterotoxin A mutant without emetic activity, as an antitumor agent in vitro and in vivo. It showed that SEA-H61D could significantly inhibit the growth of many cancer cell lines in vitro at very low concentrations by activating human peripheral blood mononuclear ...

journal_title：Cancer investigation

authors： Wang HR,Jiang H,Hao HJ,Zheng YL,Jie KG,Gu J,Jiang YQ

更新日期：2010-10-01 00:00:00

abstract：:FTIR spectroscopy is a common technique for cancer diagnosis. Applied tissue samples are heterogeneous and may be damaged in preparation procedures. Easier sampling, more available samples and also easier process with assured results would be interesting. Whole blood samples include all of these qualifications and our...

journal_title：Cancer investigation

authors： Khanmohammadi M,Ansari MA,Garmarudi AB,Hassanzadeh G,Garoosi G

更新日期：2007-09-01 00:00:00

abstract：:Nature has provided many effective anticancer agents in current use, such as the microbially derived drugs; dactinomycin; bleomycin and doxorubicin; and the plant-derived drugs, vinblastine, irinotecan, topotecan, etoposide, and paclitaxel. The search for novel antitumor agents from natural sources continues through c...

journal_title：Cancer investigation

authors： Cragg GM,Newman DJ

更新日期：1999-01-01 00:00:00

abstract：:One of the hallmarks of cancer is limitless proliferative capacity, which is tightly associated with the ability to maintain telomeres. Over the last decade, the telomere biology of pediatric cancers has begun to be elucidated. Most pediatric leukemias and embryonal solid tumors activate the enzyme telomerase, a speci...

journal_title：Cancer investigation

authors： Tabori U,Dome JS

更新日期：2007-04-01 00:00:00

abstract：:The WORLD07 study characterizes lung cancer in Spanish women. This analysis investigated lung cancer features in never-smoking women. Of 2072 women recruited, 2035 were analyzed. Patient characteristics and demographics were similar for current/former smokers and never smokers. Among never smokers, 38.3% were exposed ...

journal_title：Cancer investigation

authors： Viñolas N,Garrido P,Isla D,Provencio M,Majem M,Artal A,Carcereny E,Garcia Campelo R,Lianes P,De La Peñas R,Felip E

更新日期：2017-05-28 00:00:00

abstract：:As genetic testing for BRCA1 and BRCA2 (BRCA1/2) mutations is increasingly integrated into the clinical management of high-risk women, it will be important to understand barriers and motivations for genetic counseling among women from underserved minority groups to ensure equitable access to these services. Therefore,...

journal_title：Cancer investigation

authors： Halbert CH,Kessler LJ,Mitchell E

更新日期：2005-01-01 00:00:00

abstract：:Seven patients developed a lung abscess and bronchopleural fistula after undergoing aggressive treatment of their lung cancer with radiotherapy +/- chemotherapy. These complications were preceded by a prodrome of recurrent bronchitis with increasing refractoriness to antibiotics, weight loss, fever, and generalized de...

journal_title：Cancer investigation

authors： Frytak S,Lee RE,Pairolero PC,Arnold PG,Shaw JN

更新日期：1988-01-01 00:00:00

abstract：:Achieving a cure for metastatic neuroblastoma remains a challenge despite sensitivity to chemotherapy and radiotherapy. Most patients achieve remission, but a failure to eliminate minimal residual disease (MRD) often leads to relapse. Immunotherapy is potentially useful for chemotherapy-resistant disease and may be pa...

journal_title：Cancer investigation

authors： Modak S,Cheung NK

更新日期：2007-02-01 00:00:00

abstract：:A case control study was undertaken to investigate the association of polymorphisms in cytochrome P4501A1 (CYP1A1) with squamous cell carcinoma of head and neck (HNSCC) in North Indian population. The variant genotypes of CYP1A1*2A and CYP1A1*2C were found to be overrepresented in cases when compared to controls. The ...

journal_title：Cancer investigation

authors： Singh AP,Shah PP,Ruwali M,Mathur N,Pant MC,Parmar D

更新日期：2009-10-01 00:00:00

abstract：:Expression of epidermal growth factor and its transmembrane receptor (EGFR) stimulates tumor growth. Matuzumab is a humanized anti-EGFR monoclonal antibody that blocks EGFR activation and downstream signaling, inhibits tumor growth, and provides a clinical benefit for some patients. The plasma half-life (6-10 days) an...

journal_title：Cancer investigation

authors： Schiller JH

更新日期：2008-02-01 00:00:00

abstract：:Hospice programs do not identify burnout as a significant staff problem, even though there are many significant stressors for staff members doing hospice work. Hospices offer support in a wide variety of ways and settings through their human resources management. All this support is predicated on the assumption that t...

journal_title：Cancer investigation

authors： Brenner PR

更新日期：1997-01-01 00:00:00

abstract：:Two groups of patients with disseminated breast carcinomas who had failed radiotherapy, chemotherapy, and hormonotherapy were treated with natural interferon alpha (nIFN-alpha) alone or in combination with nIFN-gamma delivered in cycles of 10-12 intralesional (i.l.) injections to recurrent and metastatic lesions. In g...

journal_title：Cancer investigation

authors： Habif DV,Ozzello L,De Rosa CM,Cantell K,Lattes R

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:A 96-hour infusion schedule of paclitaxel demonstrates tolerability and antitumor activity in lung cancer and breast cancer refractory to short-duration infusion paclitaxel. Given the activity of paclitaxel in esophageal cancer, a phase II trial of 96-hour infusion paclitaxel in esophageal cancer was underta...

journal_title：Cancer investigation

authors： Anderson SE,O'Reilly EM,Kelsen DP,Ilson DH

更新日期：2003-01-01 00:00:00

abstract：:Psychosocial adjustment in adolescent cancer survivors has been documented to be quite variable. Factors mediating adjustment need to be identified. The current study is an exploration of the impact that cancer diagnosis and treatment has on adolescent's self-perceptions and the role this has in mediating adjustment i...

journal_title：Cancer investigation

authors： Smith K,Ostroff J,Tan C,Lesko L

更新日期：1991-01-01 00:00:00

abstract：:The host immune response can impact cancer growth, prognosis, and response to therapy. In colorectal cancer, the presence of cells involved with T-cell-mediated adaptive immunity predicts survival better than the current staging method. We used the expression of genes recently associated with host immune responses (T(...

journal_title：Cancer investigation

authors： Hsu DS,Kim MK,Balakumaran BS,Acharya CR,Anders CK,Clay T,Lyerly HK,Drake CG,Morse MA,Febbo PG

更新日期：2010-08-01 00:00:00

abstract：:In conclusion, the prognosis for women with stage I borderline tumors is excellent. Surgery alone is the recommended treatment. For young patients, fertility-sparing surgery is optimal, with a small percentage eventually developing tumor in the contralateral ovary. For patients with advanced stage borderline tumors, 1...

journal_title：Cancer investigation

authors： Gershenson DM

更新日期：1999-01-01 00:00:00

abstract：:While cancer remains an important public health concern, novel and enhanced treatment modalities have increased the length of survival of individuals diagnosed with the disease. The treatment of most cancers requires the use of chemotherapeutic agents to affect cure, maintain control of the disease, or provide palliat...

journal_title：Cancer investigation

authors： Visovsky C

更新日期：2003-06-01 00:00:00

abstract：:Although it is not proven by causative association, several studies indicate that patients with acquired immune deficiency syndrome (AIDS) have a high risk for developing cutaneous malignancies, especially lymphoma and Kaposi's sarcoma. Other malignant cutaneous lesions seen in this patient population include basal-ce...

journal_title：Cancer investigation

authors： Aboulafia DM

更新日期：1998-01-01 00:00:00

abstract：:Estrogen-related receptors (ERRs) alpha, beta, and gamma are orphan nuclear receptors that modulate the estrogen signaling pathway and play roles in the regulation of breast cancer cell growth. To determine the association between breast cancer risk and alleles of the tetranucleotide repeat (AAAG)n in the intron of ER...

journal_title：Cancer investigation

authors： Karimi P,Hematti S,Safari F,Tavassoli M

更新日期：2013-11-01 00:00:00

abstract：:We performed the analysis of database on 409 patients with LD-SCLC to evaluate as to what extent the clinical outcome of large prospective trials was reproduced in routine practice. The analysis has shown that the hazard rate of death in the absence of prophylactic cranial irradiation (PCI) adjusted for the effects of...

journal_title：Cancer investigation

authors： Wzietek I,Suwinski R,Nowara E,Bialas M,Bentzen S,Tukiendorf A

更新日期：2014-01-01 00:00:00

abstract：:Hepatitis B virus X protein (HBx) promotes hepatocellular carcinoma (HCC) invasion and metastasis by a poorly understood mechanism. This study investigated the role of NF-kappa B in HBx-mediated upregulation of vascular endothelial growth factor (VEGF) and matrix metalloproteinases (MMPs). In a stably expressing HBx c...

journal_title：Cancer investigation

authors： Liu LP,Liang HF,Chen XP,Zhang WG,Yang SL,Xu T,Ren L

更新日期：2010-06-01 00:00:00

abstract：:The microvasculature is a ubiquitous organ system having a major role in the pathogenesis of radiation damage to normal tissues. Although the kinetics of radiation damage to endothelial cells is similar to other tissues (as reflected by Do and Dq) the late effect is a manifestation of injury, not only to the endotheli...

journal_title：Cancer investigation

authors： Baker DG,Krochak RJ

更新日期：1989-01-01 00:00:00

abstract：:Metastasis is the overwhelming cause of mortality in patients with breast cancer and our understanding of its cellular and molecular determinants is limited. Among cellular determinants, disseminated (DTC) tumor cells undoubtedly are key players in the metastatic cascade. In the past, several models have been construc...

journal_title：Cancer investigation

authors： Braun S,Auer D,Marth C

更新日期：2009-07-01 00:00:00

abstract：:This study compared the antiemetic efficacy and safety of two different intravenous (i.v.) dolasetron dosing regimens in patients receiving their first course of high-dose (> or = 80 mg/m2) cisplatin. Of 30 patients enrolled, 14 received a single i.v. dolasetron dose (0.6 mg/kg) before cisplatin and 16 received a mult...

journal_title：Cancer investigation

authors： Kasimis BS,Tapazoglou E,Schulman P,Stewart WH,Hahne WF,Cramer MB

更新日期：1997-01-01 00:00:00

abstract：:Because most cancer deaths result from disseminated disease, understanding the regulation of tumor invasion and metastasis is a central theme in tumor cell biology. Interactions between extracellular matrices (ECM) and cellular microenvironment play a crucial role in this process. We have tested selected amino acids a...

journal_title：Cancer investigation

authors： Singh RK,Rinehart CA,Kim JP,Tolleson-Rinehart S,Lawing LF,Kaufman DG,Siegal GP

更新日期：1996-01-01 00:00:00

abstract：:Fingerprints from 200 women with histologically proven breast cancer (case group) were compared to fingerprints from 138 women with no history of any malignant disease (control group). Of the patterns analyzed, four were significantly associated with breast cancer: accidentals, transitionals, angled ulnar loops, and h...

journal_title：Cancer investigation

authors： Bierman HR,Faith MR,Stewart ME

更新日期：1988-01-01 00:00:00

abstract：:Radioimmunotherapy (RIT) is a promising new treatment option for patients with relapsed/refractory non-Hodgkin's lymphoma. Clinical trials have demonstrated that both iodine-131 (131I) and yttrium-90 (90Y) are suitable radionuclides for RIT. Iodine-131 and 90Y differ markedly in their physical properties including hal...

journal_title：Cancer investigation

authors： Leonard JP,Siegel JA,Goldsmith SJ

更新日期：2003-04-01 00:00:00

abstract：INTRODUCTION:The aim of this study was to compare the manganese superoxide dismutase (MnSOD) expression in matched tumor and normal tissue. METHODS:One hundred lung cancer specimens and matched normal lung parenchyma from the same patient were evaluated for MnSOD expression. RESULTS:The median normal MnSOD expression...

journal_title：Cancer investigation

authors： Martin RC,Li Y,Liu Q,Barker DF,Doll MA,Hein DW

更新日期：2010-10-01 00:00:00