Abstract:
:The effect of a crude protein fraction from human urine having gonadotropin inhibitory activity (GGIM) was observed on the growth of 7,12-dimethylbenz(a)anthracene induced mammary tumors in Holtzman rat. Results show that while in 12 out 13 tumors, tumor growth was retarded/regressed following 2--4 weeks of CGIM treatment, tumor growth in control rats was unabated. However, no positive correlation with hormone dependency and tumor regression could be established. Further, this crude anti LH material was found to be non-toxic to tumor cells in vitro.
journal_name
Neoplasmajournal_title
Neoplasmaauthors
Sarkar S,Shah PN,Bagli NPsubject
Has Abstractpub_date
1981-01-01 00:00:00pages
457-61issue
4eissn
0028-2685issn
1338-4317journal_volume
28pub_type
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