Extrahepatic biliary obstruction and liver failure secondary to myeloma of the pancreas.

abstract：:A 33-year-old male runner, who had undergone a Swanson silastic prosthetic implant for degenerative joint disease of the first metatarsal head and proximal phalanx of the right great toe, presented with unilateral inguinal lymphadenopathy. Biopsy revealed confluent, non-caseating granulomas containing silastic materia...

journal_title：Human pathology

authors： Rogers LA,Longtine JA,Garnick MB,Pinkus GS

更新日期：1988-10-01 00:00:00

abstract：:Mammary analogue secretory carcinoma (MASC) of salivary glands is a newly recognized tumor entity. To explore a more practical and convenient immunohistochemical approach to distinguish MASC from other tumors arising from salivary glands as well as to expand the immunologic and genetic lineage of MASC, we examined 17 ...

journal_title：Human pathology

authors： Ni H,Zhang XP,Wang XT,Xia QY,Lv JH,Wang X,Shi SS,Li R,Zhou XJ,Rao Q

更新日期：2016-12-01 00:00:00

abstract：:Altered expression of oncogenes and tumor suppressor genes, the normal function of which is to regulate cell growth and differentiation, represents a central event in the pathogenesis of human cancer. Aberrant expression of these genes is often a result of a mutational event. In vitro amplification of DNA with the pol...

journal_title：Human pathology

authors： Loda M

更新日期：1994-06-01 00:00:00

abstract：:Reactive bone marrow mast cells reliably lack the morphologic, immunophenotypic, and molecular features of systemic mastocytosis (SM). We report two unusual cases of acquired aplastic anemia (AA) in which multifocal aggregates of bone marrow mast cells fulfilled morphologic and immunophenotypic criteria for SM accordi...

journal_title：Human pathology

authors： Golardi N,Sramek JE,Myers JB,Saffer H,George TI,Czuchlewski DR

更新日期：2014-02-01 00:00:00

abstract：:We evaluated 173 consecutive breast carcinomas for c-erbB-2 using a combination of immunohistochemistry (IHC) with a commercial polyclonal antibody (Nitirei) and dual-color fluorescence in situ hybridization (FISH) using the c-erbB-2-specific probe and the chromosome 17 centromere-specific probe from Vysis (Downers Gr...

journal_title：Human pathology

authors： Kobayashi M,Ooi A,Oda Y,Nakanishi I

更新日期：2002-01-01 00:00:00

abstract：:Alterations of the epidermal growth factor receptor (EGFR) can be observed in a significant subset of esophageal adenocarcinomas (EACs), and targeted therapy against EGFR may become an interesting approach for the treatment of these tumors. Mutations of KRAS, NRAS, BRAF, and phosphatidylinositol-3-kinase catalytic sub...

journal_title：Human pathology

authors： Bettstetter M,Berezowska S,Keller G,Walch A,Feuchtinger A,Slotta-Huspenina J,Feith M,Drecoll E,Höfler H,Langer R

更新日期：2013-05-01 00:00:00

abstract：:Pleomorphic adenoma (PA) is the most common benign tumor of salivary glands. Carcinomas in pleomorphic adenomas (CPAs) may arise by malignant transformation of the epithelial components of PAs. Occasionally, transitional zones containing cells with histological features intermediate between those of the benign PA and ...

journal_title：Human pathology

authors： Yamamoto Y,Kishimoto Y,Virmani AK,Smith A,Vuitch F,Albores-Saavedra J,Gazdar AF

更新日期：1996-08-01 00:00:00

abstract：:A case of metastatic malignant melanoma simulating a giant cell tumor of bone is reported. This case typifies the diversity of expression of malignant melanoma. Osteoclast-like giant cells were present only in the femoral head metastasis and were not present in the primary lesion. The giant cell component may be refle...

journal_title：Human pathology

authors： Daroca PJ Jr,Reed RJ,Martin PC

更新日期：1990-09-01 00:00:00

abstract：:A cytogenetic study of an eccrine spiradenoma and two lymph node metastases, with a growth pattern and microscopic appearance typical for benign eccrine spiradenoma, revealed a 46,XY-5,del(16)(q22),+mar(t(?;5)(?::5q13----5qter)) karyotype. The finding of the same abnormal karyotype in the tumor and the metastases sugg...

journal_title：Human pathology

authors： Dijkhuizen T,van den Berg E,Nikkels PG,Hoekstra HJ,de Jong B

更新日期：1992-09-01 00:00:00

abstract：:Thrombosis of large fetal vessels in the placenta leads to regions of downstream avascular villi (AV). Avascular villi have been associated with adverse outcomes in anecdotal reports, but no controlled study of their significance has been done. We prospectively gathered cases of extensive AV (n = 29) occurring over a ...

journal_title：Human pathology

authors： Redline RW,Pappin A

更新日期：1995-01-01 00:00:00

abstract：:Geotrichum candidum was identified as an invasive organism in the terminal ileum of a man with "hairy cell" leukemia. The organism was identified on the basis of histologic and cultural characteristics. The diagnostic features of G. candidum infection are compared to those of Aspergillus and Candida species. ...

journal_title：Human pathology

authors： Jagirdar J,Geller SA,Bottone EJ

更新日期：1981-07-01 00:00:00

abstract：:Atypical mesothelial hyperplasia encountered in pleural fluid or in a pleural biopsy specimen raises the suspicion that one may be dealing with a diffuse malignant mesothelioma of the pleura. We studied eight cases with cytologic or histologic changes of mesothelial atypia thought to be suspicious for diffuse malignan...

journal_title：Human pathology

authors： Yokoi T,Mark EJ

更新日期：1991-07-01 00:00:00

abstract：:We examined the infection of herpes simplex virus (HSV), human cytomegalovirus (HCMV), and Epstein-Barr virus (EBV) in 61 autopsy cases with secondary diffuse interstitial pneumonia (SDIP) by immunohistochemistry and compared our findings with those in 46 individuals without lung complications. There was no significan...

journal_title：Human pathology

authors： Oda Y,Okada Y,Katsuda S,Nakanishi I

更新日期：1994-10-01 00:00:00

abstract：:Tubular carcinoma of the breast is a well-differentiated variant of invasive ductal carcinoma and has been shown to have an exceptionally favorable prognosis, as manifested by a low incidence of lymph node metastases and an excellent overall survival. It is unknown whether this subtype represents an early step along t...

journal_title：Human pathology

authors： Waldman FM,Hwang ES,Etzell J,Eng C,DeVries S,Bennington J,Thor A

更新日期：2001-02-01 00:00:00

abstract：:The case of an infant with endocardial fibroelastosis and a coexistent anomalous right coronary artery that originated from the pulmonary trunk is presented. The causal relation between the two conditions is discussed. ...

journal_title：Human pathology

authors： Huang TY,Hsueh Y,Tsung SH

更新日期：1985-09-01 00:00:00

abstract：:Epstein-Barr virus (EBV) is a member of the human herpesvirus family that was initially isolated from a cultured Burkitt lymphoma cell line by Epstein et al in 1964. Subsequent studies have proven that it is the causative agent in most cases of infectious mononucleosis. Primary infection is usually asymptomatic in chi...

journal_title：Human pathology

authors： Rezk SA,Weiss LM

更新日期：2007-09-01 00:00:00

abstract：:A digoxigenin-tailed, synthetic oligodeoxynucleotide was used to detect genomic hepatitis delta virus (HDV) RNA in formalin-fixed, paraffin-embedded liver sections by a nonisotopic in situ hybridization (NISH) procedure. Twenty-three liver samples from chronically HDV-infected patients were studied. Eight liver specim...

journal_title：Human pathology

authors： Pacchioni D,Negro F,Chiaberge E,Rizzetto M,Bonino F,Bussolati G

更新日期：1992-05-01 00:00:00

abstract：:A 57 year old man presented with a two week history of right sided chest pain. An admission chest x-ray examination revealed a 2 by 1 cm. lytic lesion of the ninth right rib and right sided pleural effusion. The patient underwent a right thoracotomy during which 700 cc. of blood tinged pleural fluid was drained and a ...

journal_title：Human pathology

authors： Pappas CA,Rheinlander HF,Stadecker MJ

更新日期：1980-11-01 00:00:00

abstract：:Many have wondered what might have become of the totalitarian state Lenin founded on merciless terror, had he not died so young. He was 52 and at the height of his power when he had his first stroke. Six months later he had another and then a third stroke three months after that. He died 3 months shy of his 54th birth...

journal_title：Human pathology

authors： Vinters H,Lurie L,Mackowiak PA

更新日期：2013-10-01 00:00:00

abstract：:Neoglycoproteins are readily available conjugates of a histochemically inert carrier protein and histochemically crucial carbohydrate moieties which are covalently attached to the carrier protein by chemical synthesis. Biotinylation renders these conjugates detectable in formalin-fixed, paraffin-embedded tissue sectio...

journal_title：Human pathology

authors： Kayser K,Gabius HJ,Ciesiolka T,Ebert W,Bach S

更新日期：1989-04-01 00:00:00

abstract：:Hemangiopericytoma and fibrosarcoma represented at one time two of the most common diagnoses in soft tissue pathology. Both terms are now largely extinct. This article will review the clinicopathologic, immunohistochemical and molecular genetic advances that have led to these changes, and review the pathologic feature...

journal_title：Human pathology

authors： Folpe AL

更新日期：2020-01-01 00:00:00

abstract：:Rhabdomyomas are rare tumors that usually arise within the heart, orocervical, or vulvovaginal regions. The cardiac tumors have a characteristic immature morphology, occur often in association with tuberous sclerosis, and are regarded as hamartomas rather than true neoplasms. The histogenesis of the extracardiac tumor...

journal_title：Human pathology

authors： Zwick DL,Livingston K,Clapp L,Kosnik E,Yates A

更新日期：1989-04-01 00:00:00

abstract：:Mesenchymal chondrosarcoma, a rare malignant round cell and hyaline cartilage tumor, is most commonly intraosseous but can occur in extraskeletal sites. We intensively observed the morphology and applied Sox9 (master regulator of chondrogenesis), beta-catenin (involved in bone formation, thought to inhibit chondrogene...

journal_title：Human pathology

authors： Fanburg-Smith JC,Auerbach A,Marwaha JS,Wang Z,Rushing EJ

更新日期：2010-05-01 00:00:00

abstract：:As one form of branched-chain amino-acid transaminase (BCAT) enzymes, It has been found that up-regulation of BCAT1 is associated with poor prognosis in numerous types of tumors, but studies on the role of BCAT1 expression in gastric cancer (GC) are rare. The aims of this study were to detect BCAT1 expression in GC an...

journal_title：Human pathology

authors： Xu Y,Yu W,Yang T,Zhang M,Liang C,Cai X,Shao Q

更新日期：2018-05-01 00:00:00

abstract：:In order to study the granular transformation of Sertoli cells the following testicular specimens were reviewed: 58 postmortem biopsies from 21 children and 37 young adult males with normal histologic pattern; 165 biopsies from prepubertal cryptorchid testes; 38 biopsies and 18 surgical specimens from postpubertal-cry...

journal_title：Human pathology

authors： Nistal M,Garcia-Rodeja E,Paniagua R

更新日期：1991-02-01 00:00:00

abstract：:The presence of thyroglobulin (TG) was investigated by immunohistochemistry with one polyclonal and three distinct monoclonal anti-TG antibodies in 19 primary and 15 metastatic medullary thyroid carcinoma (MTC) cases. In two primary tumors possessing a mixed trabecular and follicular growth pattern, a significant numb...

journal_title：Human pathology

authors： de Micco C,Chapel F,Dor AM,Garcia S,Ruf J,Carayon P,Henry JF,Lebreuil G

更新日期：1993-03-01 00:00:00

abstract：:Pityriasis lichenoides (PL) is a papulosquamous disorder often considered a form of reactive dermatosis and classified with small plaque parapsoriasis (digitate dermatosis). However, some patients with PL have developed large plaque parapsoriasis (LPP) and mycosis fungoides (MF), and lymphoid atypia and T-cell clonali...

journal_title：Human pathology

authors： Magro C,Crowson AN,Kovatich A,Burns F

更新日期：2002-08-01 00:00:00

abstract：:Intraductal carcinoma of the prostate (IDC-P) and high-grade prostatic intraepithelial neoplasia (HGPIN) are two distinct intraductal lesions; the former is usually associated with invasive carcinoma and has an aggressive course while the latter is considered a precancerous lesion. In addition, there are morphological...

journal_title：Human pathology

authors： Miyai K,Divatia MK,Shen SS,Miles BJ,Ayala AG,Ro JY

更新日期：2014-08-01 00:00:00

abstract：:Atypical fibro-osseous lesions, usually in the proximal femur, are a common consultative diagnostic problem. This is due to the fact that they contain a variety of patterns individually reminiscent of fibrous dysplasia, fibroxanthoma (non-ossifying fibroma), myxofibroma, lipoma, cyst, bone infarct, Paget's disease, an...

journal_title：Human pathology

authors： Ragsdale BD

更新日期：1993-05-01 00:00:00

abstract：:This study investigate the expression of the mitogen-activated protein kinases (MAPKs) in normal prostate, benign prostatic hyperplasia (BPH), and prostatic cancer (PC), and also the possible relationship between the activity of these MAPKs and the apoptosis/proliferation index. Immunochemical techniques were carried ...

journal_title：Human pathology

authors： Royuela M,Arenas MI,Bethencourt FR,Sánchez-Chapado M,Fraile B,Paniagua R

更新日期：2002-03-01 00:00:00