Silicone lymphadenopathy in a long distance runner: complication of a silastic prosthesis.

abstract：:Clear cell renal cell carcinoma (CCRCC) is the most common renal cell carcinoma. It has a relatively unfavorable prognosis compared to other common renal cell carcinomas. Recently, comprehensive molecular studies in CCRCC revealed important genetic alterations, including changes in the VHL, PBRM1, and ARID1A genes. Th...

journal_title：Human pathology

authors： Park JH,Lee C,Suh JH,Chae JY,Kim HW,Moon KC

更新日期：2015-03-01 00:00:00

abstract：:Activating transcription factor 3, a member of the activating transcription factor/cyclic adenosine monophosphate response element-binding family of transcription factors, is an adaptive response gene that plays an oncogenic role in the development of various cancers. To our knowledge, few information are available on...

journal_title：Human pathology

authors： Kim MS,In SG,Park OJ,Won CH,Lee MW,Choi JH,Kim CW,Kim SE,Moon KC,Chang S

更新日期：2011-07-01 00:00:00

abstract：:Nested urothelial carcinoma (UC) is a rare histologic variant of UC, characterized by deceptively bland histologic features resembling von Brunn's nests but usually with a poor outcome. In our experience, this variant is frequently misclassified or underrecognized as its clinicopathologic spectrum is not well defined....

journal_title：Human pathology

authors： Wasco MJ,Daignault S,Bradley D,Shah RB

更新日期：2010-02-01 00:00:00

abstract：:The distinction between Spitz nevus and melanoma is currently possible, applying a set of definite histological criteria. However, in certain lesions deviating from the stereotypical morphology of classic Spitz nevi ("atypical Spitz tumors"), the differentiation between benign and malignant cases appears problematic b...

journal_title：Human pathology

authors： Urso C,Borgognoni L,Saieva C,Ferrara G,Tinacci G,Begliomini B,Reali UM

更新日期：2006-07-01 00:00:00

abstract：:A case of a tail in a 2-week-old infant is reported, and findings from a review of 33 previously reported cases of true tails and pseudotails are summarized. The true, or persistent, vestigial tail of humans arises from the most distal remnant of the embryonic tail. It contains adipose and connective tissue, central b...

journal_title：Human pathology

authors： Dao AH,Netsky MG

更新日期：1984-05-01 00:00:00

abstract：:In this series of 3,432 cases of malignant melanoma of the choroid and ciliary body, mortality from metastasis 15 years after enucleation was 46 per cent. This mortality was at least ten times greater than has been observed with tumors of the iris, probably owing to the greater size and more malignant cytology of chor...

journal_title：Human pathology

authors： McLean IW,Foster WD,Zimmerman LE

更新日期：1982-02-01 00:00:00

abstract：:We investigated whether histological chorioamnionitis (HCA) is a risk factor predisposing to leukemoid reaction (LR) and whether LR is associated with the preterm parturition syndrome and the systemic fetal inflammation response syndrome. A prospective histological study on placentas was performed in preterm infants (...

journal_title：Human pathology

authors： Zanardo V,Vedovato S,Trevisanuto DD,Suppiej A,Cosmi E,Fais GF,Chiarelli S

更新日期：2006-01-01 00:00:00

abstract：:In this study, we aimed to identify whether tumor budding is associated with the progression and prognosis of oral squamous cell carcinoma (OSCC) and investigate the correlation between tumor budding and regulators of epithelial-mesenchymal transition (EMT). Fifty-six cases of OSCC were selected and their tumor buddin...

journal_title：Human pathology

authors： Hong KO,Oh KY,Shin WJ,Yoon HJ,Lee JI,Hong SD

更新日期：2018-10-01 00:00:00

abstract：:We report 13 cases of unique polypoid urothelial tumors with inverted growth pattern (PUTIPs) occurring in the proximal ureter and renal pelvis. We describe their morphologic features and further characterize them in regard to TERT promoter mutation status and microsatellite instability. Thirteen cases were identified...

journal_title：Human pathology

authors： Wobker SE,Zhong M,Epstein JI

更新日期：2017-01-01 00:00:00

abstract：:Multicentric Castleman disease (MCD) is a systemic inflammatory disease potentially caused by an increase in the serum interleukin-6 (IL-6) level. Idiopathic MCD (iMCD) is histopathologically classified into three types: plasmacytic (PC), mixed, and hypervascular (hyperV) types. Recently, a unique clinical phenotype w...

journal_title：Human pathology

authors： Kurose N,Futatsuya C,Mizutani KI,Kumagai M,Shioya A,Guo X,Aikawa A,Nakada S,Fujimoto S,Kawabata H,Masaki Y,Takai K,Aoki S,Kojima M,Nakamura S,Yamada S

更新日期：2018-07-01 00:00:00

abstract：:Recent studies demonstrated that protease-activated receptor-2 (PAR-2) correlates with tumor progression in various tissues. On the other hand, oxidative stress arising from endometriosis has been considered a cause of carcinogenesis in ovarian clear cell carcinoma (OCCC). We previously demonstrated that oxidative str...

journal_title：Human pathology

authors： Aman M,Ohishi Y,Imamura H,Shinozaki T,Yasutake N,Kato K,Oda Y

更新日期：2017-06-01 00:00:00

abstract：:Monocytoid B-cell lymphoma (MBCL) is a newly recognized, morphologically and immunologically distinct, low-grade B-cell neoplasm that may exist as a pure morphologic entity or as a component of a composite lymphoma. To determine whether cytogenetic abnormalities exist in cases of MBCL, fresh tissue from four lymphoma ...

journal_title：Human pathology

authors： Slovak ML,Weiss LM,Nathwani BN,Bernstein L,Levine AM

更新日期：1993-10-01 00:00:00

abstract：:Hepatoid adenocarcinoma is an extrahepatic tumor characterized by morphological similarities to hepatocellular carcinoma. The lesions contain a tubular adenocarcinoma that seems to develop "hepatoid" features, but the relation between the tubular adenocarcinomatous and the hepatoid components remains unclear. We compa...

journal_title：Human pathology

authors： Kumashiro Y,Yao T,Aishima S,Hirahashi M,Nishiyama K,Yamada T,Takayanagi R,Tsuneyoshi M

更新日期：2007-06-01 00:00:00

abstract：:We aimed to study the expression of phosphorylated vascular endothelial growth factor receptor 2 (pVEGFR-2), a membrane-bound tyrosine kinase receptor to vascular endothelial growth factor, in 76 cases of leukemia and nonneoplastic myeloproliferative disease and in 8 reactive bone marrows. The microvessel density (MVD...

journal_title：Human pathology

authors： Zhang Y,Pillai G,Gatter K,Blázquez C,Turley H,Pezzella F,Watt SM

更新日期：2005-07-01 00:00:00

abstract：:Clinical stage I seminomas are effectively treated with surgery raising concerns as to when to give adjuvant radiation therapy given the risk of secondary malignancies. A recent randomized trial found tumor size and rete testis invasion to be the strongest predictors of relapse in clinical stage I seminomas. These 2 p...

journal_title：Human pathology

authors： Browne TJ,Richie JP,Gilligan TD,Rubin MA

更新日期：2005-06-01 00:00:00

abstract：:This study tested whether concordance could be achieved for abnormal inflammation in the basal decidua of placental specimens among 6 pathologists experienced in placental pathology. Thirty microscope slides were evaluated by the pathologists for chronic deciduitis. They also scored the severity and extent of inflamma...

journal_title：Human pathology

authors： Khong TY,Bendon RW,Qureshi F,Redline RW,Gould S,Stallmach T,Lipsett J,Staples A

更新日期：2000-03-01 00:00:00

abstract：:Loss of the NF1 allele, coding for the protein neurofibromin, and polymorphism in the proto-oncogene RET (RETp) are purportedly common in desmoplastic melanoma (DM). DM is categorized into pure (PDM) and mixed (MDM) subtypes, which differ in prognosis. Most NF1 mutations result in a truncated/absent protein, making im...

journal_title：Human pathology

authors： Kadokura A,Frydenlund N,Leone DA,Yang S,Hoang MP,Deng A,Hernandez-Perez M,Biswas A,Singh R,Yaar R,Mahalingam M

更新日期：2016-07-01 00:00:00

abstract：:Human epidermal growth factor receptor 2 (HER2) status is useful for predicting response to trastuzumab. Fluorescence in situ hybridization (FISH) for HER2 gene amplification is accurate but limited because of cost, the need for fluorescence microscopy, the limited assessment of histology, and the fading of its signal...

journal_title：Human pathology

authors： Lim SJ,Cantillep A,Carpenter PM

更新日期：2013-11-01 00:00:00

abstract：:Hepatitis C virus (HCV) infection may be complicated by non-Hodgkin's lymphoma through yet unknown pathogenetic mechanisms. We describe the case of a patient with HCV-related cirrhosis who developed a primary effusion lymphoma (PEL) of Burkitt's type confined to the peritoneal cavity, in the absence of immunodeficienc...

journal_title：Human pathology

authors： Ascoli V,Lo Coco F,Artini M,Levrero M,Fruscalzo A,Mecucci C

更新日期：1997-01-01 00:00:00

abstract：:NLRC3 is a member of the nucleotide-binding domain and leucine-rich repeat (NLR) family protein that plays a role in inflammation and immunity. Although chronic inflammation has been identified as a hallmark of cancer, NLRC3 expression correlation with the development and prognosis of hepatocellular carcinoma (HCC) is...

journal_title：Human pathology

authors： Ma YY,Zhang GH,Li J,Wang SB,Hu ZM,Zhang CW,Li E

更新日期：2018-12-01 00:00:00

abstract：:Langerhans cell histiocytosis (LCH) is a group of granulomatous disorders in which abnormal Langerhans cells proliferate as either a localized lesion in a single bone or disseminated disease involving two or more organs or systems. Because the different LCH forms exhibit significantly elevated levels of inflammatory m...

journal_title：Human pathology

authors： Murakami I,Matsushita M,Iwasaki T,Kuwamoto S,Kato M,Horie Y,Hayashi K,Imamura T,Morimoto A,Imashuku S,Gogusev J,Jaubert F,Takata K,Oka T,Yoshino T

更新日期：2014-01-01 00:00:00

abstract：:Insulin-like growth factor II messenger RNA (mRNA)-binding protein 3 (IMP3) is an oncofetal protein that promotes tumor progression and metastasis in a number of malignancies. However, the clinical significance of IMP3 expression in squamous cell carcinoma (SCC) of the uterine cervix is unclear. In this study, the cor...

journal_title：Human pathology

authors： Wei Q,Yan J,Fu B,Liu J,Zhong L,Yang Q,Zhao T

更新日期：2014-11-01 00:00:00

abstract：:Villin (V) is a glycoprotein of microvilli associated with rootlet formation. Most colonic adenocarcinomas have a V positive (+), cytokeratin (CK) 20 (+), CK7-negative (-) immunophenotype; most lung adenocarcinomas have a CK20(-), CK7(+) immunophenotype. The reports of villin immunoreactivity in lung adenocarcinoma ra...

journal_title：Human pathology

authors： Tan J,Sidhu G,Greco MA,Ballard H,Wieczorek R

更新日期：1998-04-01 00:00:00

abstract：:Using analysis of allelic loss (loss of heterozygosity [LOH]), we previously reported a putative progression pathway from germ cell neoplasia in situ (GCNIS) to seminoma and then to embryonal carcinoma in mixed-type testicular germ cell tumors. To identify the genetic backgrounds related to the progression of nonsemin...

journal_title：Human pathology

authors： Miyai K,Ito K,Nakanishi K,Tsuda H

更新日期：2019-02-01 00:00:00

abstract：:We herein report an 18-month-old girl who presented with a retroperitoneal mature teratoma that later developed into an endodermal sinus tumor. Her symptoms included an expanding abdominal girth. The serum levels of alpha-fetoprotein were moderately elevated. The excised specimen was a benign mature cystic retroperito...

journal_title：Human pathology

authors： Ohno Y,Kanematsu T

更新日期：1998-10-01 00:00:00

abstract：:This study explored the importance of hepatitis B virus infection in cholangiocarcinoma pathogenesis in northern China. The clinical data of 66 patients with cholangiocarcinoma were analyzed. The hepatitis B virus gene was amplified using nested polymerase chain reaction, and the hepatitis B virus-related antigen was ...

journal_title：Human pathology

authors： Wu Y,Wang T,Ye S,Zhao R,Bai X,Wu Y,Abe K,Jin X

更新日期：2012-01-01 00:00:00

abstract：:Abnormal nuclear megakaryocytic staining for phospho-STAT5 (pSTAT5) correlates with JAK2 V617F mutational status in non-chronic myelogenous leukemia chronic myeloproliferative disorders. However, a proportion of wild-type JAK2 non-chronic myelogenous leukemia chronic myeloproliferative disorders cases also demonstrate...

journal_title：Human pathology

authors： Gibson SE,Schade AE,Szpurka H,Bak B,Maciejewski JP,Hsi ED

更新日期：2008-07-01 00:00:00

abstract：:This article describes a case of lymphomatoid granulomatosis without active pulmonary involvement of stigmata of healed granulomatous lesions in the lungs. The patient had ischemic segmental colitis due to mesenteric arterial intimal fibrosis, which we interpreted as spontaneously regressed granulomatous involvement o...

journal_title：Human pathology

authors： Singh G,Hellstrom HR

更新日期：1978-05-01 00:00:00

abstract：:Renal cell carcinoma (RCC) with sarcomatoid changes and rhabdoid features has shown poor outcomes. Several immune checkpoint inhibitors including programmed cell death protein 1 (PD-1)/programmed death ligand-1 (PD-L1) inhibitors have been approved for the treatment of RCC. Combination therapy using PD-1/PD-L1 and ind...

journal_title：Human pathology

authors： Kiyozawa D,Takamatsu D,Kohashi K,Kinoshita F,Ishihara S,Toda Y,Eto M,Oda Y

更新日期：2020-07-01 00:00:00

abstract：:The types of collagen present in a case of elastofibroma dorsi were determined using type specific, characterized collagen antibodies. The presence of type II collagen (normally present only in articular cartilage and in selected ocular structures) is discussed with regard to the pathogenesis of this lesion, and the u...

journal_title：Human pathology

authors： Madri JA,Dise CA,LiVolsi VA,Merino MJ,Bibro MC

更新日期：1981-02-01 00:00:00