Estrogen treatment of dyskinetic disorders.

Abstract:

:Estrogen have been reported in animal studies to both enhance and block central dopaminergic activity and in one clinical report to improve tardive dyskinesia. In the present study estrogen (Premarin, 2.5 mg per day) administration caused varying degrees of improvement in less than one-third of 21 patients with chorea due to Huntington's disease and tardive dyskinesia and had no effect in eight patients with dystonia. Estrogens appear to have an antidopaminergic effect in humans but poses only limited efficacy in the treatment of dyskinetic disorders.

journal_name

Neurology

journal_title

Neurology

authors

Koller WC,Barr A,Biary N

doi

10.1212/wnl.32.5.547

subject

Has Abstract

pub_date

1982-05-01 00:00:00

pages

547-9

issue

5

eissn

0028-3878

issn

1526-632X

journal_volume

32

pub_type

临床试验,杂志文章,随机对照试验
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    abstract::Cross-sectional studies have not adequately resolved the question of whether subjects infected with HIV-1 may suffer cognitive decline during the early, asymptomatic stages of the infection. We studied longitudinally 238 asymptomatic healthy HIV-1-infected homosexual/bisexual men (CDC groups 2 and 3) and 170 uninfecte...

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    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1212/wnl.40.2.204

    authors: Selnes OA,Miller E,McArthur J,Gordon B,Muñoz A,Sheridan K,Fox R,Saah AJ

    更新日期:1990-02-01 00:00:00

  • Identification of risk factors for autism spectrum disorders in tuberous sclerosis complex.

    abstract:OBJECTIVE:The purpose of this study was to assess the prevalence of and to identify epidemiologic, genetic, electrophysiologic, and neuroanatomic risk factors for autism spectrum disorders (ASD) in a cohort of patients with tuberous sclerosis complex (TSC). METHODS:A total of 103 patients with TSC were evaluated for A...

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    pub_type: 杂志文章

    doi:10.1212/WNL.0b013e3182104347

    authors: Numis AL,Major P,Montenegro MA,Muzykewicz DA,Pulsifer MB,Thiele EA

    更新日期:2011-03-15 00:00:00

  • Prediction of pathology in primary progressive language and speech disorders.

    abstract:OBJECTIVE:Frontotemporal lobar degeneration (FTLD) encompasses a variety of clinicopathologic entities. The antemortem prediction of the underlying pathologic lesions is reputed to be difficult. This study sought to characterize correlations between 1) the different clinical variants of primary progressive language and...

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    doi:10.1212/WNL.0b013e3181c7198e

    authors: Deramecourt V,Lebert F,Debachy B,Mackowiak-Cordoliani MA,Bombois S,Kerdraon O,Buée L,Maurage CA,Pasquier F

    更新日期:2010-01-05 00:00:00

  • Serum-mediated oligodendrocyte cytotoxicity in multiple sclerosis patients and controls.

    abstract::We examined serum-mediated cytotoxicity on cultured rat oligodendrocytes, using serum from patients with acute or chronic progressive multiple sclerosis and normal controls. We found heat-labile serum factors in serum from MS and also in controls. The cytotoxic effects of MS and normal sera were not restored by adding...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.36.2.276

    authors: Hirayama M,Lisak RP,Silberberg DH

    更新日期:1986-02-01 00:00:00

  • The psychosocial consequences of pediatric multiple sclerosis.

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    journal_title:Neurology

    pub_type: 杂志文章,评审

    doi:10.1212/01.wnl.0000259420.54635.63

    authors: MacAllister WS,Boyd JR,Holland NJ,Milazzo MC,Krupp LB,International Pediatric MS Study Group.

    更新日期:2007-04-17 00:00:00

  • PM2.5 associated with gray matter atrophy reflecting increased Alzheimers risk in older women.

    abstract:OBJECTIVE:To examine whether late-life exposure to PM2.5 (particulate matter with aerodynamic diameters <2.5-µm) contributes to progressive brain atrophy predictive of Alzheimer's disease (AD) using a community-dwelling cohort of women (aged 70-89) with up to two brain MRI scans (MRI-1: 2005-6; MRI-2: 2010-11). METHOD...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000011149

    authors: Younan D,Wang X,Casanova R,Barnard R,Gaussoin SA,Saldana S,Petkus AJ,Beavers DP,Resnick SM,Manson JE,Serre ML,Vizuete W,Henderson VW,Sachs BC,Salinas JA,Gatz M,Espeland MA,Chui HC,Shumaker SA,Rapp SR,Chen JC,Wom

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  • Subarachnoid and intracerebral hemorrhage: natural history, prognosis, and precursive factors in the Framingham Study.

    abstract::No uniformly accepted hypothesis explains the genesis and rupture of intracranial aneurysms. We followed 5,184 men and women prospectively for 26 years; 36 cases of aneurysmal subarachnoid hemorrhage (SAH) accounted for 62% of all intracranial hemorrhages. Blood pressure before SAH was higher in these patients than in...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.34.7.847

    authors: Sacco RL,Wolf PA,Bharucha NE,Meeks SL,Kannel WB,Charette LJ,McNamara PM,Palmer EP,D'Agostino R

    更新日期:1984-07-01 00:00:00

  • Serum elements and oxidative status in clinically isolated syndromes: imbalance and predictivity.

    abstract:BACKGROUND:Metals are suspected of being involved in the pathogenesis of various neurologic diseases. We previously found a complex imbalance in serum chemical elements and oxidative status in patients with clinically definite multiple sclerosis (CDMS). OBJECTIVE:To understand whether this imbalance affects people wit...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0b013e31820af7de

    authors: Ristori G,Brescianini S,Pino A,Visconti A,Vittori D,Coarelli G,Cotichini R,Bocca B,Forte G,Pozzilli C,Pestalozza I,Stazi MA,Alimonti A,Salvetti M

    更新日期:2011-02-08 00:00:00

  • IgG Fc-receptor polymorphisms in Guillain-Barré syndrome.

    abstract::The authors studied immunoglobulin G (IgG) Fc receptor (FcgammaR) IIA, IIIA, and IIIB polymorphisms in 62 patients with Guillain-Barré syndrome (GBS) and in 89 healthy controls. The FcgammaR genotypes and allele frequencies did not differ significantly between the patients with GBS and the controls. Patients homozygou...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.55.5.705

    authors: Vedeler CA,Raknes G,Myhr KM,Nyland H

    更新日期:2000-09-12 00:00:00

  • Transient ischemic attacks: a prospective study of 225 patients.

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    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.28.8.746

    authors: Toole JF,Yuson CP,Janeway R,Johnston F,Davis C,Cordell AR,Howard G

    更新日期:1978-08-01 00:00:00

  • Clinical and electroencephalographic correlation of independent multifocal spike discharges.

    abstract::One hundred and eight patients with independent, multifocal, spike discharges in the EEG were studied. The abnormality occurred at all ages but was more frequent between 4 and 7 years. The basic EEG activity in wake tracing was invariably slow for the age of the patient. The majority of the patients with independent m...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.26.7.667

    authors: Noriega-Sanchez A,Markand ON

    更新日期:1976-07-01 00:00:00

  • Cerebellar hemorrhage complicating isovaleric acidemia: a case report.

    abstract::Isovaleric acidemia (IVA) is an inborn error of leucine metabolism, resulting in an accumulation of isovaleric acid in the body fluids. The neuropathologic findings in an 11-day-old infant with IVA consisted of diffuse cerebral edema, massive cerebellar hemorrhage, upward transtentorial herniation, and focal degenerat...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.31.6.746

    authors: Fischer AQ,Challa VR,Burton BK,McLean WT

    更新日期:1981-06-01 00:00:00

  • Homozygosity for the transthyretin-Met30 gene in three Japanese siblings with type I familial amyloidotic polyneuropathy.

    abstract::We report the cases of three siblings homozygous for a mutated transthyretin (TTR) gene that causes type I familial amyloidotic polyneuropathy (FAP), in whom we made the diagnosis by identifying both the mutated TTR gene and a variant TTR in their sera. Their serum levels for the variant TTR are twice those of patient...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.42.10.2045

    authors: Yoshinaga T,Nakazato M,Ikeda S,Ohnishi A

    更新日期:1992-10-01 00:00:00

  • Acetyl-dl-leucine in Niemann-Pick type C: A case series.

    abstract:OBJECTIVE:To assess the effects of the modified amino acid acetyl-dl-leucine (AL) on cerebellar ataxia, eye movements, and quality of life of patients with Niemann-Pick type C (NP-C) disease. METHODS:Twelve patients with NP-C disease were treated with AL 3 g/d for 1 week and then with 5 g/d for 3 weeks with a subseque...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000002041

    authors: Bremova T,Malinová V,Amraoui Y,Mengel E,Reinke J,Kolníková M,Strupp M

    更新日期:2015-10-20 00:00:00

  • Body mass index and the risk of Parkinson disease.

    abstract:OBJECTIVE:To examine the association between body mass index (BMI) and the risk of Parkinson disease (PD). METHODS:Study cohorts included 22,367 Finnish men and 23,439 women 25 to 59 years of age without a history of PD at baseline. Hazards ratios (HRs) of incident PD were estimated for different levels of BMI. RESUL...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/01.wnl.0000247052.18422.e5

    authors: Hu G,Jousilahti P,Nissinen A,Antikainen R,Kivipelto M,Tuomilehto J

    更新日期:2006-12-12 00:00:00

  • Surgical treatment of carpal tunnel syndrome in patients with peripheral neuropathy.

    abstract::Outcome after carpal tunnel surgery was studied retrospectively in 32 patients with peripheral neuropathy and carpal tunnel syndrome. Nocturnal paresthesias were almost universally relieved, followed in order of responsiveness by pain, numbness, and weakness. Twenty-five of 28 patients said they would have the surgery...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.49.4.1159

    authors: Morgenlander JC,Lynch JR,Sanders DB

    更新日期:1997-10-01 00:00:00

  • Adrenergic innervation in autonomic failure.

    abstract::In 10 patients with chronic autonomic failure, the sympathetic perivascular nerve plexuses from quadriceps muscle biopsies were studied by catecholamine fluorescence and electronmicroscopy. There was almost complete absence of catecholamine fluorescence and fewer than normal numbers of small granular (noradrenergic) v...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.31.12.1501

    authors: Bannister R,Crowe R,Eames R,Burnstock G

    更新日期:1981-12-01 00:00:00

  • Survival and outcome after endotracheal intubation for acute stroke.

    abstract:OBJECTIVE:To assess survival and functional outcome in patients endotracheally intubated after ischemic stroke (IS) or spontaneous intracerebral hemorrhage (ICH). BACKGROUND:Endotracheal intubation is both a necessary life support intervention and a measure of severity in IS or ICH. Knowledge of associated clinical va...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.52.7.1374

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    更新日期:1999-04-22 00:00:00

  • Recurrent cerebral ischemia in medically treated patent foramen ovale: a meta-analysis.

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    journal_title:Neurology

    pub_type: 杂志文章,meta分析,评审

    doi:10.1212/WNL.0b013e3181aa2a19

    authors: Almekhlafi MA,Wilton SB,Rabi DM,Ghali WA,Lorenzetti DL,Hill MD

    更新日期:2009-07-14 00:00:00

  • Lewy bodies are not increased in progressive supranuclear palsy compared with normal controls.

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    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.57.9.1675

    authors: Tsuboi Y,Ahlskog JE,Apaydin H,Parisi JE,Dickson DW

    更新日期:2001-11-13 00:00:00

  • Brain amyloid load and its associations with cognition and vascular risk factors in FINGER Study.

    abstract:OBJECTIVE:To investigate brain amyloid pathology in a dementia-risk population defined as cardiovascular risk factors, aging, and dementia risk (CAIDE) score of at least 6 but with normal cognition and to examine associations between brain amyloid load and cognitive performance and vascular risk factors. METHODS:A sub...

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    更新日期:2018-01-16 00:00:00

  • Effects of intermittent levetiracetam dosing in a patient with refractory daily seizures.

    abstract::Some epilepsy patients quickly develop resistance to antiepileptic drugs (AEDs). We report a case of a patient with refractory epilepsy with daily seizures who initially responded to levetiracetam daily therapy, but then returned to baseline seizure frequency. However, when levetiracetam was given once weekly, the pat...

    journal_title:Neurology

    pub_type: 杂志文章

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    authors: Friedman D,French JA

    更新日期:2006-02-28 00:00:00

  • Cardiac sources of embolism and cerebral infarction--clinical consequences and vascular concomitants: the Lausanne Stroke Registry.

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    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.41.6.855

    authors: Bogousslavsky J,Cachin C,Regli F,Despland PA,Van Melle G,Kappenberger L

    更新日期:1991-06-01 00:00:00

  • Arterial wall properties in carotid artery dissection: an ultrasound study.

    abstract:BACKGROUND:Cervical artery dissection is often attributed to an underlying arteriopathy related to a generalized extracellular matrix defect. OBJECTIVE:The authors compared the hemodynamic and morphologic properties of the carotid artery, as assessed noninvasively by ultrasonography, in patients with spontaneous inter...

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    更新日期:2000-09-12 00:00:00

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    pub_type: 杂志文章,评审

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    pub_type: 杂志文章

    doi:10.1212/wnl.42.7.1311

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    更新日期:2021-01-06 00:00:00

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    更新日期:2017-08-08 00:00:00

  • Short- and long-term outcome of chronic pallidal neurostimulation in monogenic isolated dystonia.

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    authors: Brüggemann N,Kühn A,Schneider SA,Kamm C,Wolters A,Krause P,Moro E,Steigerwald F,Wittstock M,Tronnier V,Lozano AM,Hamani C,Poon YY,Zittel S,Wächter T,Deuschl G,Krüger R,Kupsch A,Münchau A,Lohmann K,Volkmann J,Kle

    更新日期:2015-03-03 00:00:00

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    doi:10.1212/wnl.45.3.569

    authors: Gunderson CH

    更新日期:1995-03-01 00:00:00