Abstract:
OBJECTIVE:Postoperative pancreatic fistula (POPF) and readmission remain the significant sources of morbidity after distal pancreatectomy (DP). We describe a technique of drainage and postoperation management to prevent severe POPF and readmission. METHODS:A retrospective analysis of 57 patients who underwent DP from January 2009 to November 2011 was conducted. The drain was placed just abutting the pancreatic stump by suturing the tissue near the stump. Each patient was discharged carrying an intraabdominal drain, and a strict follow-up was made in the outpatient clinic. Postoperative pancreatic fistula was defined using the international study group classification for pancreatic fistula definition. RESULTS:Thirty-two patients accepted laparoscopic DP (LDP), and 25 patients accepted open DP (ODP). There was no significant difference in the rate of POPF between the 2 groups (12/32 vs 11/25, P = 0.786). All the POPF cases were grades A and B, but no case was grade C. No case needed a specific intervention. There was no reoperation, readmission, intraabdominal abscess, or surgical site infection. CONCLUSIONS:We conclude that our technique of drainage and postoperation management is associated with a low incidence of severe POPF and readmission. Continued investigation of this technique is warranted.
journal_name
Pancreasjournal_title
Pancreasauthors
Wang H,Xiu D,Jiang B,Ma C,Yuan Cdoi
10.1097/MPA.0000000000000072subject
Has Abstractpub_date
2014-05-01 00:00:00pages
588-91issue
4eissn
0885-3177issn
1536-4828pii
00006676-201405000-00014journal_volume
43pub_type
杂志文章相关文献
PANCREAS文献大全abstract::Although previous reports suggest interactions between the endocrine and the exocrine pancreas, insulin's effect on pancreatic exocrine function remains unclear. Chronic pancreatic fistulae were created in five dogs; these animals were studied using the euglycemic, hyperinsulinemic clamp technique. After a 30-min unst...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/00006676-199605000-00004
更新日期:1996-05-01 00:00:00
abstract::Phospholipase C (PLC) isozymes are believed to play a role in regulating pancreatic exocrine and endocrine secretion. In an attempt to investigate the role of PLC, we examined the distribution patterns of PLC isozymes in the normal rat pancreas by Western blot analysis and immunohistochemistry. Western blot analysis w...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/00006676-200101000-00008
更新日期:2001-01-01 00:00:00
abstract::Relative adrenal insufficiency is common in patients with severe sepsis and septic shock. We describe three patients with severe acute pancreatitis who developed signs suggestive of adrenal insufficiency during the early phase of the disease. Clinical features and possible causes of adrenal insufficiency are discussed...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/00006676-200310000-00009
更新日期:2003-10-01 00:00:00
abstract::In dispersed acini from rat pancreas, verapamil (a phenylalkylamine calcium channel blocker) potentiated amylase secretion stimulated by vasoactive intestinal peptide (VIP), secretin, peptide histidine isoleucine, helodermin, forskolin, and 8-bromocyclic AMP. The action of verapamil on VIP-stimulated amylase secretion...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/00006676-199303000-00012
更新日期:1993-03-01 00:00:00
abstract:OBJECTIVE:The transcription factor Stat1 is a member of the family of signal transducers and transcription activators and responds to interferon-γ stimulation. p21 is a p53-responsive gene for cell cycle regulation and mediates Stat1 antitumor activity. The aim of this study was to analyze their expression for predicti...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/MPA.0000000000000074
更新日期:2014-05-01 00:00:00
abstract::Diabetes mellitus secondary to chronic pancreatitis is characterized by a progressive destruction of the pancreas, including loss of the islet cells, leading to a form of diabetes that can mimic both type 1 and type 2 diabetes. Glucagon-like peptide 1(7-36)amide (GLP-1), an intestinally derived insulinotropic hormone,...
journal_title:Pancreas
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00006676-200001000-00004
更新日期:2000-01-01 00:00:00
abstract:OBJECTIVES:Amylase level in drains (ALD) has been proposed as a predictor for the development of a clinically significant pancreatic fistula (CS-PF) in patients undergoing a major pancreatic surgery. This study aimed to determine if the ALD in patients who developed a CS-PF after pancreatoduodenectomy is higher than th...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/MPA.0000000000000060
更新日期:2014-04-01 00:00:00
abstract::We investigated the role of platelet-activating factor (PAF) as a priming signal for cytokine-induced neutrophil chemoattractant (CINC) expression by bronchoalveolar macrophages in acute pancreatitis. Pancreatitis was induced by four intramuscular injections of cerulein (50 micrograms/kg at 1-h intervals) in Wistar ra...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/00006676-199905000-00005
更新日期:1999-05-01 00:00:00
abstract::The prognosis of patients with alpha-fetoprotein (AFP)-producing pancreatic cancer is generally very poor. We, however, present a case of a 33-year-old man who survived AFP-producing pancreatic cancer and its metachronous liver metastasis. The patient had undergone a curative total pancreatectomy for AFP-producing pan...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/01.mpa.0000179727.15716.82
更新日期:2005-11-01 00:00:00
abstract:OBJECTIVES:Secretin stimulation testing (SST) is used to evaluate patients with hypergastrinemia in the diagnosis of Zollinger-Ellison syndrome. Case series have documented false-positive SST in patients with achlorhydria. This study reviews our experience with SST in hypochlorhydric and achlorhydric patients. METHODS...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/MPA.0b013e3182847b2e
更新日期:2013-08-01 00:00:00
abstract::Free radicals have been implicated in beta-cell destruction. pancreatic antioxidant enzymatic defenses provide significant endogenous protection from these highly cytotoxic effector molecules. In our colony of BB rats, the reliability of peripheral blood lymphocyte count (PBLC) as a predictor of diabetes onset was ass...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/00006676-199501000-00007
更新日期:1995-01-01 00:00:00
abstract::The clinical, diagnostic, and therapeutic aspects of 27 patients with pancreatopleural fistula (PPF) reported in the literature, and two additional patients managed by the authors, form the basis of this report. The diagnosis of PPF is based on the triad of massive pleural effusions, elevated pleural fluid amylase, an...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/00006676-198605000-00013
更新日期:1986-01-01 00:00:00
abstract:OBJECTIVES:The postoperative morbidity after pancreatectomy remains high. The role of somatostatin and its analogs in reducing complications after pancreatic resection is controversial. The aim of the study was to evaluate the ability of somatostatin to influence pancreatic cell's function with consequence the decrease...
journal_title:Pancreas
pub_type: 杂志文章,随机对照试验
doi:10.1097/MPA.0b013e3182557c24
更新日期:2013-01-01 00:00:00
abstract:INTRODUCTION:Islet cell transplantation offers a new approach for the treatment of diabetes. Before transplantation, immunomodulation procedures are conducted to reduce the immunogenicity of the pancreatic islets. AIM:To study the effect of cyclophosphamide pretreatment and culture on the xenograft survival of monkey ...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/00006676-200204000-00005
更新日期:2002-04-01 00:00:00
abstract:OBJECTIVES:Endoscopic ultrasound (EUS) quality benchmarks for pancreatic disease previously focused on maintaining thresholds of diagnostic accuracy for fine-needle aspiration and measuring complications. We aimed to evaluate quality indicators when performing EUS specifically for the diagnosis of chronic pancreatitis ...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/MPA.0b013e3182a85e1e
更新日期:2014-01-01 00:00:00
abstract:OBJECTIVES:Despite decades of effort, the 5-year overall survival rate of pancreatic cancer (PC) remains at only approximately 5%. Until now, no detailed knowledge regarding the worldwide research architecture of PC has yet been established. METHODS:Hence, we conducted this scientometric analysis to quantify the globa...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/MPA.0000000000000693
更新日期:2016-11-01 00:00:00
abstract:OBJECTIVE:We aimed to investigate preoperative findings that are useful to distinguish intraductal papillary-mucinous neoplasm (IPMN) subtypes. METHODS:One hundred twenty-three patients who underwent pancreatectomy for IPMN were analyzed clinicopathologically and radiologically. Invasive IPM carcinomas (IPMCs) were su...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/MPA.0b013e318181b90d
更新日期:2009-01-01 00:00:00
abstract:OBJECTIVES:Patients undergoing therapeutic endoscopic retrograde cholangiopancreatography (ERCP) are at a higher risk of developing post-ERCP pancreatitis than patients undergoing diagnostic ERCP. The aim of this study was to evaluate the effectiveness of somatostatin in preventing post-therapeutic ERCP pancreatitis. ...
journal_title:Pancreas
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1097/MPA.0b013e3181733721
更新日期:2008-11-01 00:00:00
abstract:OBJECTIVES:Hypertriglyceridemia-induced pancreatitis is an important cause of acute pancreatitis (AP) in children, which lacks established guidelines. The aim of this study was to review management approaches at a single pediatric center. METHODS:This retrospective study included all inpatients younger than 21 years w...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/MPA.0000000000001505
更新日期:2020-03-01 00:00:00
abstract:OBJECTIVE:The aim of the study was to determine if there had been any change in the number of solid-pseudopapillary neoplasm (SPN) cases detected and their evaluation or management over time. METHODS:A systematic review of SPN was performed of all articles published in English in PubMed and Scopus. RESULTS:A total of...
journal_title:Pancreas
pub_type: 杂志文章,评审
doi:10.1097/MPA.0000000000000061
更新日期:2014-04-01 00:00:00
abstract:OBJECTIVES:The aim of this prospective study was to evaluate the diagnostic value of the rapid urinary trypsinogen-2 test strip in post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis. METHODS:A total of 150 patients were tested with the urinary trypsinogen-2 test strip and serum levels of amylase a...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/MPA.0b013e31821fcdcf
更新日期:2011-11-01 00:00:00
abstract:INTRODUCTION:Although somatostatin inhibits pancreatic exocrine secretion, the inhibitory mechanism of endogenous somatostatin is not clearly understood. AIM:To investigate the effect of endogenous somatostatin on the interaction between endogenous insulin and exogenous cholecystokinin (CCK) in exocrine secretion of t...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/00006676-200205000-00008
更新日期:2002-05-01 00:00:00
abstract::Despite the new diagnostic and therapeutic advancements, acute pancreatitis has still high rate of morbidity and mortality. We aimed to evaluate the effects of hyperbaric oxygen (HBO) therapy alone or combined with S-methylisothiourea (SMT), and meropenem (MER) therapy in an experimental rat model of acute necrotizing...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/00006676-200401000-00008
更新日期:2004-01-01 00:00:00
abstract::Utilizing scanning electron microscopy and isolated, vascularly perfused rat pancreas, we studied the angioarchitecture and the effect of the insulinotropic hormone, gastric inhibitory polypeptide (GIP), on cholecystokinin (CCK)-stimulated exocrine secretion. We tried to correlate the microcirculation with the physiol...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/00006676-198701000-00016
更新日期:1987-01-01 00:00:00
abstract::To evaluate the effect of the prostaglandin inhibitor acetylsalicylic acid (ASA) on rat exocrine pancreas secretion, three groups of rats were administered ASA by infusion: Groups 1-3, 50, 100, and 200 mg/kg body wt, respectively; Group 4 received saline. Twenty minutes later these ASA-pretreated groups were given int...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/00006676-199307000-00003
更新日期:1993-07-01 00:00:00
abstract::Twelve patients with acute pancreatitis admitted to our department between January 1993 and December 1994 were studied prospectively and classified into two groups (severe group, five patients; mild group, seven patients), according to the criteria for grading severity of acute pancreatitis proposed by the Research Co...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/00006676-199701000-00001
更新日期:1997-01-01 00:00:00
abstract::Radical pancreaticoduodenectomy was performed for cancer of the head of the pancreas in a 65-year-old male patient with congenital celiac occlusion. Preoperative angiography revealed that the arterial flow to the liver, spleen, and stomach was supplied via the pancreaticoduodenal arcade and that the dorsal pancreatic ...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/00006676-199105000-00014
更新日期:1991-05-01 00:00:00
abstract::Chemokines may regulate the process of immune cell infiltration that is often found in pancreatic cancer. In this study, we investigated the secretion of the chemokines [interleukin (IL)-8, monocyte chemoattractant protein (MCP)-1, and RANTES (regulated on activation, normal T cell expressed and secreted)] in human pa...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/00006676-200007000-00049
更新日期:2000-07-01 00:00:00
abstract:OBJECTIVES:Human telomerase reverse transcriptase (hTERT), one of the subunits of telomerase, is a promising diagnostic marker for pancreatic cancer. In the present study, we did a large-scale analysis of 115 preoperative pancreatic juice specimens to evaluate the feasibility of detection of hTERT expression by immunoh...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/MPA.0b013e3181a16d28
更新日期:2009-07-01 00:00:00
abstract::Acute pancreatitis generates a complex cascade of immunological events that affect the pathogenesis and the progression of this disease. Several inflammatory mediators seem to play a critical role in the pathogenesis of pancreatitis and the subsequent inflammatory response. In turn, these mediators can influence hemos...
journal_title:Pancreas
pub_type: 杂志文章,评审
doi:10.1097/01.mpa.0000240617.66215.d2
更新日期:2007-01-01 00:00:00