[Effect of gestational diabetes on adiposity indicators during the first 18 years of life; systematic review].

Abstract:

INTRODUCTION:Gestational diabetes has been associated with obesity later in life. However, reported results have not been consistent and the methods used have shown weakness. OBJECTIVE:To analize prospective and retrospective cohort studies that assess the gestational diabetes effects on adiposity indicators in the offspring during their first 18 years. METHODOLOGY:A search was made for prospective or retrospective cohort studies registered in Medline/ Pubmed database, from January 2011 to September 2013 that evaluated the gestational diabetes effects on adiposity indicators at birth or after birth. RESULTS:Eleven studies met the inclusion criteria. A total of 472,959 pairs of mother and child were studied. Children age at the moment of evaluation ranged from birth to 18 years. In nine out of eleven articles an association between gestational diabetes and adiposity indicators was observed. In seven studies adjustments for potential confounders (pre gestational BMI, maternal age) were made. In five of those an association between gestational diabetes and adiposity was found. CONCLUSION:The results of this review indicate that the evidence showing that gestational diabetes increase adiposity indicators later in life is moderate. :Introducción: La diabetes gestacional ha sido asociada con la obesidad en períodos posteriores de la vida. Sin embargo, los resultados no han sido consistentes y algunos estudios contenían debilidades metodológicas. Objetivo: Analizar los resultados de estudios prospectivos y retrospectivos de cohorte que evalúen el efecto de la diabetes gestacional sobre indicadores de adiposidad en los hijos hasta los 18 años de edad. Metodología: Se realizó una búsqueda de estudios prospectivos o retrospectivos de cohorte registrados en la base de datos de Medline/Pubmed, de enero de 2011 a septiembre de 2013, que valoraran el efecto de la Diabetes Gestacional sobre los indicadores de adiposidad al nacimiento o después del nacimiento. Resultados: Once estudios cumplían con los criterios de inclusión. En total se estudiaron a 472.959 pares de madre e hijo. La edad del niño en el momento de la evaluación fue a partir del nacimiento hasta los 18 años. En nueve de once artículos se observó una asociación entre la diabetes gestacional e indicadores de obesidad. En siete de trabajos se realizaron ajustes para más de dos variables de confusión (IMC pre gestacional, edad de la madre), y en cinco de ellos se observó una asociación entre la diabetes gestacional con adiposidad. Conclusión: Los resultados de la revisión indican que la evidencia que demuestra que la diabetes gestacional aumenta el peso de los productos en períodos posteriores de la vida, es moderada.

journal_name

Nutr Hosp

journal_title

Nutricion hospitalaria

authors

Jiménez Cruz A,Ortega Cisneros A,Bacardí Gascón M

doi

10.3305/nh.2014.29.2.7042

subject

Has Abstract

pub_date

2014-02-01 00:00:00

pages

397-401

issue

2

eissn

0212-1611

issn

1699-5198

journal_volume

29

pub_type

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