The syndrome of frontal lobe epilepsy: characteristics and surgical management.

abstract：:A model of latent infection by varicella-zoster virus (VZV) was obtained in the adult rat. Inoculation of VZV-infected cells in the skin led to infection of the peripheral nervous system. Latency was characterized by a long-lasting presence of the viral genome, of selected viral gene transcripts, and of at least one v...

journal_title：Neurology

authors： Sadzot-Delvaux C,Debrus S,Nikkels A,Piette J,Rentier B

更新日期：1995-12-01 00:00:00

abstract：OBJECTIVE:To study the efficacy and safety of low-dose oral tetrahydrocannabinol (THC) in the treatment of dementia-related neuropsychiatric symptoms (NPS). METHODS:This is a randomized, double-blind, placebo-controlled study. Patients with dementia and clinically relevant NPS were randomly assigned to receive THC 1.5...

journal_title：Neurology

authors： van den Elsen GA,Ahmed AI,Verkes RJ,Kramers C,Feuth T,Rosenberg PB,van der Marck MA,Olde Rikkert MG

更新日期：2015-06-09 00:00:00

abstract：:A clinical procedure for determining contrast sensitivity was performed on patients with suspected sella area masses. The test consisted of a series of six plates, each containing a bar pattern of fixed sinusoidal spatial frequency in which contrast varies along the length of the bar. Patients with compressive lesions...

journal_title：Neurology

authors： Kupersmith MJ,Siegel IM,Carr RE

更新日期：1981-05-01 00:00:00

abstract：BACKGROUND:Cerebral infarctions are common in older persons but their relationship with dementia and cognitive function remains controversial. METHODS:Participants were 164 older Catholic nuns, priests, and brothers who underwent annual clinical evaluation and brain autopsy at death. The authors quantified number and ...

journal_title：Neurology

authors： Schneider JA,Wilson RS,Cochran EJ,Bienias JL,Arnold SE,Evans DA,Bennett DA

更新日期：2003-04-08 00:00:00

abstract：:The authors demonstrate the potential for poststroke return of activation in regions normally involved in touch discrimination in a serial, whole-brain fMRI study of a patient with marked sensory loss followed by good recovery. A return of activation in ipsilesional primary and bilateral secondary somatosensory cortic...

journal_title：Neurology

authors： Carey LM,Abbott DF,Puce A,Jackson GD,Syngeniotis A,Donnan GA

更新日期：2002-09-10 00:00:00

abstract：:Current concepts suggest that avoidance of pulsatile stimulation of dopamine receptors in Parkinson's disease (PD) can prevent the onset of dyskinesia. In MPTP-treated primates, repeated administration of levodopa or other short-acting dopamine agonist drugs leads to the onset of marked involuntary movements. In contr...

journal_title：Neurology

authors： Jenner P

更新日期：2004-01-13 00:00:00

abstract：:The epsilon 4 isoform of apolipoprotein E (Apo-E) may confer genetic susceptibility for familial and sporadic Alzheimer's disease (AD). Because dementia in AD and Parkinson's disease (PD) share many biologic and clinical features, we determined the Apo-E genotypes for 79 patients with PD, 22 of whom were demented, and...

journal_title：Neurology

authors： Marder K,Maestre G,Cote L,Mejia H,Alfaro B,Halim A,Tang M,Tycko B,Mayeux R

更新日期：1994-07-01 00:00:00

abstract：OBJECTIVE:To test the hypothesis that brain pathology is associated with total daily physical activity proximate to death in older adults. METHODS:We studied brain autopsies from 428 decedents of the Rush Memory and Aging Project. The quantity of all physical activity was measured continuously for up to 10 days with a...

journal_title：Neurology

authors： Buchman AS,Dawe RJ,Yu L,Lim A,Wilson RS,Schneider JA,Bennett DA

更新日期：2018-05-22 00:00:00

abstract：OBJECTIVE:The MS Functional Composite (MSFC), a recently developed outcome measure for clinical trials, was applied to 240 patients with MS to explore its utility in different subgroups of MS and for comparison with the Expanded Disability Status Scale (EDSS). METHOD:Three clinical dimensions were examined: arm/hand f...

journal_title：Neurology

authors： Kalkers NF,de Groot V,Lazeron RH,Killestein J,Adèr HJ,Barkhof F,Lankhorst GJ,Polman CH

更新日期：2000-03-28 00:00:00

abstract：:A new cerebral disorder, described in three unrelated children, has recognizable clinical, radiologic, and neuropathologic findings. The onset occurs from early infancy to adolescence with slowing of cognitive performance, rare convulsive seizures, and a mixture of extrapyramidal, cerebellar, and pyramidal signs. CT s...

journal_title：Neurology

authors： Labrune P,Lacroix C,Goutières F,de Laveaucoupet J,Chevalier P,Zerah M,Husson B,Landrieu P

更新日期：1996-05-01 00:00:00

abstract：OBJECTIVE:To examine the lifetime prevalence and the concordance risk of cluster headache (CH) in a twin sample representative of the Swedish general population. METHODS:The authors assessed CH as defined by the second edition of the International Classification of Headache Disorders in 31,750 registered twins born fr...

journal_title：Neurology

authors： Ekbom K,Svensson DA,Pedersen NL,Waldenlind E

更新日期：2006-09-12 00:00:00

abstract：OBJECTIVE:To determine the role of circulating microvesicles (MV) on long-term cardiovascular outcomes after stroke, we measured them in patients with first-ever stroke with a 3-year follow-up. METHODS:In the Prospective Cohort With Incident Stroke Berlin (PROSCIS-B), patients with first-ever ischemic stroke were foll...

journal_title：Neurology

authors： Huo S,Kränkel N,Nave AH,Sperber PS,Rohmann JL,Piper SK,Heuschmann P,Landmesser U,Endres M,Siegerink B,Liman TGG

更新日期：2020-11-12 00:00:00

abstract：:Estrogen have been reported in animal studies to both enhance and block central dopaminergic activity and in one clinical report to improve tardive dyskinesia. In the present study estrogen (Premarin, 2.5 mg per day) administration caused varying degrees of improvement in less than one-third of 21 patients with chorea...

journal_title：Neurology

authors： Koller WC,Barr A,Biary N

更新日期：1982-05-01 00:00:00

abstract：:We performed an open-label study testing the effects of GM1 ganglioside on 10 Parkinson's disease (PD) patients. Patients received 1,000 mg of GM1 by IV infusion after the last of three baseline functional assessments. Patients then self-administered GM1 at a dose of 200 mg/d, by subcutaneous injection, for 18 weeks. ...

journal_title：Neurology

authors： Schneider JS,Roeltgen DP,Rothblat DS,Chapas-Crilly J,Seraydarian L,Rao J

更新日期：1995-06-01 00:00:00

abstract：:We evaluated the therapeutic efficacy and toxicity of high-dose monotherapy, using carbamazepine or phenytoin, in patients with previously uncontrolled seizures. Treatment with a single drug was equal to or better than polypharmacy, but only a few patients became free of seizures. Toxicity was mild and associated with...

journal_title：Neurology

authors： Lesser RP,Pippenger CE,Lüders H,Dinner DS

更新日期：1984-06-01 00:00:00

abstract：OBJECTIVE:To determine whether physical activity and body mass index (BMI) predict instrumental or basic activities of daily living (I/ADL) trajectories before or after stroke compared to individuals who remained stroke-free. METHODS:Using a prospective cohort, the Health and Retirement Study, we followed adults witho...

journal_title：Neurology

authors： Rist PM,Capistrant BD,Mayeda ER,Liu SY,Glymour MM

更新日期：2017-05-02 00:00:00

abstract：:Article abstract-The authors analyzed whether the pituitary gland enlarges in intracranial hypotension syndrome by studying 11 consecutive patients. Initial MRI scans showed pituitary gland enlargement with a convex superior margin. Follow-up MRI studies revealed that the size of the gland invariably diminished in all...

journal_title：Neurology

authors： Alvarez-Linera J,Escribano J,Benito-León J,Porta-Etessam J,Rovira A

更新日期：2000-12-26 00:00:00

abstract：:The urinary excretion of some important phenylethylamines, catecholamines, their metabolites, amphetamine, and methamphetamine were measured in parkinsonian patients on Sinemet (L-dopa plus carbidopa, a peripheral dopadecarboxylase inhibitor) and depressed patients after chronic (-) deprenyl treatment. Deprenyl was ef...

journal_title：Neurology

authors： Karoum F,Chuang LW,Eisler T,Calne DB,Liebowitz MR,Quitkin FM,Klein DF,Wyatt RJ

更新日期：1982-05-01 00:00:00

abstract：:The term "Wernicke's area" is most often used as an anatomical label for the gyri forming the lower posterior left sylvian fissure. Although traditionally this region was held to support language comprehension, modern imaging and neuropsychological studies converge on the conclusion that this region plays a much large...

journal_title：Neurology

authors： Binder JR

更新日期：2015-12-15 00:00:00

abstract：OBJECTIVE:To define a clinical syndrome associated with active drug abuse in HIV-infected individuals. METHODS:We performed a retrospective review to identify individuals treated at the Johns Hopkins Hospital from 1993 to 2008 who were HIV-infected and were actively abusing drugs and had bilateral basal ganglia lesion...

journal_title：Neurology

authors： Newsome SD,Johnson E,Pardo C,McArthur JC,Nath A

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:The pathogenesis of stroke-like episodes in patients with mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS) remains unknown. METHODS:Fourteen stroke-like episodes in six patients with MELAS were studied using clinical, neuroradiologic, and electrophysiologic approaches...

journal_title：Neurology

authors： Iizuka T,Sakai F,Suzuki N,Hata T,Tsukahara S,Fukuda M,Takiyama Y

更新日期：2002-09-24 00:00:00

abstract：BACKGROUND:Breastfeeding is known to have beneficial effects, but there is concern that breastfeeding during antiepileptic drug (AED) therapy may be harmful to cognitive development. Animal and human studies have demonstrated that some AEDs can adversely affect the immature brain. However, no investigation has examined...

journal_title：Neurology

authors： Meador KJ,Baker GA,Browning N,Clayton-Smith J,Combs-Cantrell DT,Cohen M,Kalayjian LA,Kanner A,Liporace JD,Pennell PB,Privitera M,Loring DW,NEAD Study Group.

更新日期：2010-11-30 00:00:00

abstract：OBJECTIVE:Cell-based therapies are being investigated as an adjunct to IV thrombolysis or mechanical thrombectomy in ischemic stroke. This review summarizes the potential applications as well as challenges of intravascular cell delivery in ischemic stroke. METHOD:We conducted a search of Medline as well as the clinica...

journal_title：Neurology

authors： Misra V,Ritchie MM,Stone LL,Low WC,Janardhan V

更新日期：2012-09-25 00:00:00

abstract：OBJECTIVES:Abnormal high cerebral iron deposition may be implicated in chronic neurologic disorders, including multiple sclerosis (MS). R2* relaxometry has been recently validated in a postmortem study to indicate brain iron accumulation in a quantitative manner. We used this technique to assess brain iron levels in di...

journal_title：Neurology

authors： Khalil M,Langkammer C,Ropele S,Petrovic K,Wallner-Blazek M,Loitfelder M,Jehna M,Bachmaier G,Schmidt R,Enzinger C,Fuchs S,Fazekas F

更新日期：2011-11-01 00:00:00

abstract：:We studied five patients with nonhemorrhagic thalamic infarction with neuropsychological tests, CT, and somatosensory evoked responses (SERs). The three patients with left thalamic lesions had abnormalities of language, memory, visuospatial processing, intellect, and personality-changes compatible with dementia. The t...

journal_title：Neurology

authors： Graff-Radford NR,Eslinger PJ,Damasio AR,Yamada T

更新日期：1984-01-01 00:00:00

abstract：:Systematic screening of many compounds in animal models led to identification of the established antiepileptic drugs (AEDs). By contrast, the newer AEDs were specifically designed to enhance an inhibitory process or to inhibit a specific excitatory pathway. However, it was later discovered that some of the designed dr...

journal_title：Neurology

authors： Moshé SL

更新日期：2000-01-01 00:00:00

abstract：:The authors describe the outcome of five patients with a cardiac thrombus selected among 183 patients with stroke (2.7 %) who were given IV tissue plasminogen activator (tPA). No early systemic or cerebral embolism occurred. Two patients made a complete recovery at 3 months. Two patients had a moderate outcome. One pa...

journal_title：Neurology

authors： Derex L,Nighoghossian N,Perinetti M,Honnorat J,Trouillas P

更新日期：2001-12-11 00:00:00

abstract：OBJECTIVE:To study prevalence of and factors contributing to burnout, career satisfaction, and well-being in US neurology residents and fellows. METHODS:A total of 938 US American Academy of Neurology member neurology residents and fellows were surveyed using standardized measures of burnout, career satisfaction, and ...

journal_title：Neurology

authors： Levin KH,Shanafelt TD,Keran CM,Busis NA,Foster LA,Molano JRV,O'Donovan CA,Ratliff JB,Schwarz HB,Sloan JA,Cascino TL

更新日期：2017-08-01 00:00:00

abstract：:Recent genetic studies show that the apolipoprotein E epsilon 4 allele (ApoE-epsilon 4) is a risk factor for Alzheimer's disease (AD). If ApoE-epsilon 4 individuals develop AD as they get older, we would expect a decrease in ApoE-epsilon 4 allele frequency with increasing age. We found a marked decline in ApoE-epsilon...

journal_title：Neurology

authors： Rebeck GW,Perls TT,West HL,Sodhi P,Lipsitz LA,Hyman BT

更新日期：1994-08-01 00:00:00

abstract：OBJECTIVE:To prospectively evaluate the effect of pump-infused intrathecal baclofen infusion (ITB) in therapeutic doses on sleep quality and on daytime and nighttime respiratory function in patients with severe spasticity. METHODS:We prospectively evaluated 20 consecutive patients (mean +/- SD age 45 +/- 13 years). We...

journal_title：Neurology

authors： Bensmail D,Quera Salva MA,Roche N,Benyahia S,Bohic M,Denys P,Bussel B,Lofaso F

更新日期：2006-10-24 00:00:00