Adrenergic lipolysis in immobilized and perfused adipocytes.

abstract：:Body surface potential maps have and certainly will have a very important role in the field of clinical arrhythmology, specifically for the localization of accessory pathways, for the detection of the origin of ventricular arrhythmias and for the identification of patients at risk of sudden death. In this particular s...

journal_title：Physiological research

authors： De Ambroggi L,Santambrogio C

更新日期：1993-01-01 00:00:00

abstract：:Through the analysis of the common apolipoprotein (apo) E gene polymorphism in large Caucasian population study with the PCR and subsequent restriction analysis, we have identified carriers of mutant allele Arg136-->Ser. Both of them (71-years-old female and her 43-years-old son) have normal lipid parameters. We sugge...

journal_title：Physiological research

authors： Hubácek JA,Adámková V,Skodová Z

更新日期：2005-01-01 00:00:00

abstract：:T-2 toxin and its metabolite HT-2 toxin are one of the most toxic mycotoxins of type A-trichothecenes, which are produced mainly by Fusarium species. Therefore, study of Fusarium toxins T-2 toxin and HT-2 toxin is an essential issue because they could also play role in failures of reproductive functions as well as end...

journal_title：Physiological research

authors： Kolesarova A,Maruniakova N,Kadasi A,Halenar M,Marak M,Sirotkin AV

更新日期：2017-09-22 00:00:00

abstract：:Eukaryotic cytochrome c oxidase (CcO), the terminal component of the mitochondrial electron transport chain is a heterooligomeric complex that belongs to the superfamily of heme-copper containing terminal oxidases. The enzyme, composed of both mitochondrially and nuclear encoded subunits, is embedded in the inner mito...

journal_title：Physiological research

authors： Stiburek L,Hansikova H,Tesarova M,Cerna L,Zeman J

更新日期：2006-01-01 00:00:00

abstract：:The mood and behavior of individuals result from an orchestra of many factors. Among them steroids play an important role; however, only several common hormones have been investigated in this respect. It has been demonstrated that some steroid metabolites long considered merely the products of steroid hormone metaboli...

journal_title：Physiological research

authors： Dušková M,Hill M,Bičíková M,Šrámková M,Řípová D,Mohr P,Stárka L

更新日期：2015-01-01 00:00:00

abstract：:In this report, we dealt with ventricular activation abnormalities in 30 patients with previous non-Q myocardial infarction (MI) by means of the CARDIAG 128.1 device, which enables analysis of ECGs, VCGs and body surface potential maps. The diagnosis was verified by left ventriculography, echocardiography and perfusio...

journal_title：Physiological research

authors： Stovícek P,Stojan M,Kasalický J,Vondrácek V,Vojácek J,Linhart A,Anger Z

更新日期：1993-01-01 00:00:00

abstract：:Perinatal hypoxemia may have serious long-term effects on the adult cardiovascular system and may lead to sex-dependent changes in cardiac tolerance to acute ischemia in adult life. The aim of the study was to answer the question whether gonadectomy of the male and female rats in the early phase of ontogenetic develop...

journal_title：Physiological research

authors： Netuka I,Szárszoi O,Malý J,Říha H,Turek D,Ostádalová I,Ostádal B

更新日期：2010-01-01 00:00:00

abstract：:Recently an expert consensus document advised to standardize user procedures and a new cut-off value for carotid-femoral pulse wave velocity in daily practice. Our aim was to observe aortic pulse wave velocity (PWVao) and augmentation index (AIXao) in two high cardiovascular risk groups: patients with verified coronar...

journal_title：Physiological research

authors： Lenkey Z,Illyés M,Böcskei R,Husznai R,Sárszegi Z,Meiszterics Z,Molnár FT,Hild G,Szabados S,Cziráki A,Gaszner B

更新日期：2014-01-01 00:00:00

abstract：:Endometrial cancer is one of the most frequent gynecological malignancies present in more than 95 % of all uterine cancers. In spite of that, screening of such disease is not commonly performed in clinical practice due to enormous costs and relatively low sensitivity. Therefore, developing an effective screening test ...

journal_title：Physiological research

authors： Kacírová M,Bober P,Alexovič M,Tomková Z,Tkáčiková S,Talian I,Mederová L,Bérešová D,Tóth R,Andrašina I,Kožlejová Z,Kilík R,Divín R,Sabo J

更新日期：2019-12-30 00:00:00

abstract：:Kainic acid (KA) is a potent neurotoxic substance valuable in research of temporal lobe epilepsy. We tested how subconvulsive dose of KA influences spontaneous behavior of adult Wistar rats. Animals were treated with 5 mg/kg of KA and tested in Laboras open field test for one hour in order to evaluate various behavior...

journal_title：Physiological research

authors： Riljak V,Marešová D,Pokorný J,Jandová K

更新日期：2015-01-01 00:00:00

abstract：:Methylphenidate is commonly used for the treatment of attention deficit hyperactivity disorder. The cardiovascular safety of methylphenidate has been a subject of debate with some studies indicating that methylphenidate increases the likelihood of experiencing a myocardial infarction. However, it is unknown whether me...

journal_title：Physiological research

authors： Seeley SL,D'Souza MS,Stoops TS,Rorabaugh BR

更新日期：2020-11-16 00:00:00

abstract：:The GH4C1 pituitary cell line, an excellent model for a thyroid hormone action study, was used for determination of the relationship between thyroid hormone receptor occupancy and intensity of cell proliferation, prolactin (PRL) production, thyrotropin (TSH) inhibition and 3,5,3,-L-triiodothyronine (T3) receptor down-...

journal_title：Physiological research

authors： Filipcík P,Strbák V,Brtko J

更新日期：1998-01-01 00:00:00

abstract：:Intrauterine and perinatal life are critical periods for programming of cardiometabolic diseases. However, their relative role remains controversial. We aimed to assess, at weaning, sex-dependent alterations induced by fetal or postnatal nutritional interventions on key organs for metabolic and cardiovascular control....

journal_title：Physiological research

authors： Munoz-Valverde D,Rodríguez-Rodríguez P,Gutierrez-Arzapalo PY,López de Pablo AL,Carmen González M,López-Giménez R,Somoza B,Arribas SM

更新日期：2015-01-01 00:00:00

abstract：:Circadian clock plays an essential role in orchestrating daily physiology, and its disruption can evoke metabolic diseases such as obesity. L-Carnitine can reduce blood lipid levels, and ameliorate fatty liver through regulating lipid metabolism. However, whether L-Carnitine administration may affect the disturbance o...

journal_title：Physiological research

authors： Xie X,Guo A,Wu T,Hu Q,Huang L,Yao C,Zhao B,Zhang W,Chi B,Lu P,Zhao Z,Fu Z

更新日期：2017-11-24 00:00:00

abstract：:Pattern of right ventricular pressure (RVP) fall and its afterload dependence were examined by analyzing ventricular pressure curves and corresponding pressure dP/dt phase planes obtained in both ventricles in the rat heart in situ. Time and value of dP/dt(min), and the time constant tau were measured at baseline and ...

journal_title：Physiological research

authors： Correia-Pinto J,Henriques-Coelho T,Magalhães S,Leite-Moreira AF

更新日期：2004-01-01 00:00:00

abstract：:Hepcidin, a recently discovered antimicrobial peptide synthesized in the liver, was identified to be the key mediator of iron metabolism and distribution. Despite our knowledge of hepcidin increased in recent years, there are only limited data on hepcidin regulation during systemic inflammatory response in human subje...

journal_title：Physiological research

authors： Maruna P,Vokurka M,Lindner J

更新日期：2011-01-01 00:00:00

abstract：:Leptin, an adipocyte-derived signaling factor, is a member of the IL-6 cytokine family. However there is no direct evidence of leptin stimulation of the acute phase protein (APP) synthesis which is typical for all other IL-6-like factors. The purpose of this study was to characterize the dynamics of circulating leptin...

journal_title：Physiological research

authors： Maruna P,Gürlich R,Frasko R,Haluzík M

更新日期：2001-01-01 00:00:00

abstract：:The goal of this study was to identify small molecular weight compounds that bind to sclerostin using in-silico methods because of the established importance of sclerostin-based therapies for the treatment of disease characterized by low bone mass. The zinc database (Zdb) revealed that nine potential molecules bind to...

journal_title：Physiological research

authors： Muthusamy K,Mohan S,Nagamani S,Kesavan C

更新日期：2016-11-23 00:00:00

abstract：:Fever developing after intracerebral injections of lipopolysaccharide (LPS) to guinea-pigs were monophasic, with only one peak of inner body temperature slowly developing and longlasting in a dose range 20 to 200 ng of LPS. Latency time was inversely related to the dose of LPS. Indomethacin injected to the third brain...

journal_title：Physiological research

authors： Spízková K,Stefl B

更新日期：1992-01-01 00:00:00

abstract：:Progesterone and estradiol are the foremost steroid hormones in human pregnancy. However, the origin of maternal progesterone has still not been satisfactorily explained, despite the generally accepted opinion that maternal LDL-cholesterol is a single substrate for placental synthesis of maternal progesterone. The que...

journal_title：Physiological research

authors： Hill M,Pařízek A,Jirásek JE,Jirkovská M,Velíková M,Dušková M,Klímková M,Pasková A,Zizka Z,Germanová A,Koucký M,Kalousová M,Stárka L

更新日期：2010-01-01 00:00:00

abstract：:Antagonists of GABA(B) receptors are expected to have proconvulsant action also in developing brain. Two antagonists (CGP55845 and CGP46381) were tested in a model of cortical epileptic afterdischarges (ADs) in 12-, 18- and 25-day-old rat pups with implanted electrodes. CGP55845 was dissolved in dimethylsulfoxide and ...

journal_title：Physiological research

authors： Mareš P

更新日期：2013-01-01 00:00:00

abstract：:The purpose of this study was to determine if there is flow-mediated vasodilation of the femoral artery in response to progressive increases in flow within a physiological range observed in the in vivo experiments. Femoral artery blood flow was determined in conscious rabbits (n = 5) using chronically implanted flowpr...

journal_title：Physiological research

authors： Clifford PS,Madden JA,Hamann JJ,Buckwalter JB,Valic Z

更新日期：2010-01-01 00:00:00

abstract：:The left and right ventricle originate from distinct parts of the cardiac tube, and several genes are known to be differentially expressed in these compartments. The aims of this study were to determine developmental differences in gene expression between the left and right ventricle, and to assess the effect of alter...

journal_title：Physiological research

authors： Krejčí E,Pesevski Z,DeAlmeida AC,Mrug M,Fresco VM,Argraves WS,Barth JL,Cui X,Sedmera D

更新日期：2012-01-01 00:00:00

abstract：:New knowledge about the neural aspects of cough has revealed a complex network of pathways that initiate cough. The effect of inflammation on cough neural processing occurs at multiple peripheral and central sites within the nervous system. Evidence exists that direct or indirect neuroimmune interaction induces a comp...

journal_title：Physiological research

authors： Kunc P,Fabry J,Lucanska M,Zatko T,Grendar M,Pecova R

更新日期：2020-03-27 00:00:00

abstract：:We studied the psychophysiology of soluble intercellular adhesion molecule-1 (sICAM-1) in 25 apparently healthy middle-aged men who underwent an acute psychosocial stressor three times with one week apart. Measures of the biological stress response were obtained at week one and three. The magnitude of the sICAM-1 stre...

journal_title：Physiological research

authors： von Känel R,Preckel D,Kudielka BM,Fischer JE

更新日期：2007-01-01 00:00:00

abstract：:A new approach to computer modelling of neuronal stochastic activity is described. The output dynamic activity which depends on the types and the number of input synapses, weights of the synaptic efficacy, the absolute refractory phase duration and threshold level is evaluated on this model in some types of Gaussian i...

journal_title：Physiological research

authors： Novák V,Schmidt J

更新日期：1996-01-01 00:00:00

abstract：:The role of the cortico-tectal pathways in the processing of auditory signals was investigated by recording the click-evoked responses and extracellular multiple unit activity in the inferior colliculus (IC) after functional ablation of the auditory cortex (AC) by local intracortical application of a sodium channel bl...

journal_title：Physiological research

authors： Nwabueze-Ogbo FC,Popelár J,Syka J

更新日期：2002-01-01 00:00:00

abstract：:Spontaneous activity of cortical neurons exhibits alternative fluctuations of membrane potential consisting of phased depolarization called "up-state" and persistent hyperpolarization called "down-state" during slow wave sleep and anesthesia. Here, we examined the effects of sound stimuli (noise bursts) on neuronal ac...

journal_title：Physiological research

authors： Zhang Y,Han L,Xiao X,Hu B,Ruan H,Xiong Y

更新日期：2011-01-01 00:00:00

abstract：:We investigated the effects of telmisartan, the blocker of angiotensin II receptor 1, on the regulation of systolic blood pressure (SBP) and oxidative stress through endothelial nitric oxide (NO) release in spontaneously hypertensive rats (SHRs). SHRs randomly received placebo, oral feeding of telmisartan (5 mg/kg or ...

journal_title：Physiological research

authors： Xu L,Liu Y

更新日期：2013-01-01 00:00:00

abstract：:We investigated whether polyethylene glycol-coated Fe3O4 nanoparticles (IONs), acute stress and their combination modifies vascular functions, nitric oxide synthase (NOS) activity, mean arterial pressure (MAP) as well as hepcidin and ferritin H gene expressions in Wistar-Kyoto rats. Rats were divided into control, ION...

journal_title：Physiological research

authors： Líšková S,Bališ P,Mičurová A,Kluknavský M,Okuliarová M,Puzserová A,Škrátek M,Sekaj I,Maňka J,Valovič P,Bernátová I

更新日期：2020-12-22 00:00:00