Abstract:
:In this study 1155 injection drug users (IDUs) receiving targeted intervention in five cities of Punjab were surveyed; three cities (Amritsar, Taran-Taran, Batala) were in districts sharing an international border with Pakistan and the other two were Jalandhar and Ludhiana. Information on socio-demography, substance use and sexual practices were collected; blood samples were tested for biologic markers. HIV and HCV antibody (HCVAb) prevalences in injection drug users were 29 and 49%, respectively. Of the HCVAb-seroreactive IDUs, 33% had HIV as well. HIV prevalence in young IDUs (≤19 years), estimated as surrogate for HIV incidence, was high at 12% and HCVAb in this subgroup was 27%. Herpes simplex virus 2 antibody (IgG) was detected in 10% of IDUs; 2% had syphilis. Alcohol use prevalence was high and frequency of use concerning. In multivariate analyses, 'city of residence closer to international border' and '>1 year duration of injecting drugs were associated with HIV and HCVAb. Furthermore, 'irregular supply of syringes and needles' was associated with HCVAb seroreactive status of IDUs (adjusted odds ratio 1.7; 95% CI 1.3-2.3;P < 0.001), and 'any genital disease symptom within the last year' (adjusted odds ratio 2; 95% CI 1.4-2.9;P < 0.001) was associated with HIV infection. Alcohol and sexual risk reduction, strengthening of needle-syringe exchange, reducing injecting duration and clinical management of HIV, HCV and HIV/HCV co-infection appear as four core programme needs.
journal_name
Int J STD AIDSjournal_title
International journal of STD & AIDSauthors
Panda S,Roy T,Pahari S,Mehraa J,Sharma N,Singh G,Singh J,Joseph F,Singh S,Sharma NMdoi
10.1177/0956462413515659subject
Has Abstractpub_date
2014-07-01 00:00:00pages
596-606issue
8eissn
0956-4624issn
1758-1052pii
0956462413515659journal_volume
25pub_type
杂志文章abstract::Despite successes in efforts to integrate HIV testing into routine care in emergency departments, challenges remain. Kiosk-facilitated, directed HIV self-testing offers one novel approach to address logistical challenges. Emergency department patients, 18-64 years, were recruited to evaluate use of tablet-based-kiosks...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462413487321
更新日期:2013-09-01 00:00:00
abstract::Renal transplant recipients represent a patient subgroup for whom the effective treatment of genital warts poses a significant problem in genitourinary medicine. This case demonstrates the safe and effective treatment of resistant perianal warts in a male renal transplant recipient using imiquimod. ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462021925180
更新日期:2002-05-01 00:00:00
abstract::The clinical utility of genotypic drug resistance testing (DRT) in HIV-infected children on antiretroviral therapy (ART) is not well understood. HIV-infected patients aged <19 years undergoing DRT for virological failure were retrospectively enrolled. Indications for DRT and changes in HIV RNA load were recorded. Betw...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462412473958
更新日期:2013-07-01 00:00:00
abstract:SUMMARY:The objective of this study was to identify factors associated with (i) longer patient travel time to genitourinary (GU) medicine clinics and (ii) not attending the nearest clinic. Questionnaires were completed by 4600 new attendees from seven sociodemographically and geographically different GU clinics across ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2008.008205
更新日期:2008-12-01 00:00:00
abstract::In a previous internal audit of women attending the department of genitourinary medicine following rape, we noted that data from diagnostic coding seemed to underestimate the problem and that anecdotally, a number of women had been seen with concerns relating to historical assault. We therefore decided to record atten...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462991912926
更新日期:1999-01-01 00:00:00
abstract::Little information is available on the prevalence of herpes simplex type-2 (HSV-2) antibodies among groups at potential high risk of HIV in Asia. This study was carried out to determine the prevalence of HSV-2 antibodies and correlates of HSV-2 infection in female sex workers (FSWs) in border provinces of Vietnam. Nin...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/095646206778691176
更新日期:2006-11-01 00:00:00
abstract::This study examines the use of various direct observation therapy-HAART treatment support modalities in Jos, Nigeria. A 12-month observational study enrolling 175 antiretroviral naïve patients into four arms of direct observation therapy-HAART (highly active antiretroviral therapy); daily observed therapy (DOT), twice...
journal_title:International journal of STD & AIDS
pub_type: 临床试验,杂志文章
doi:10.1258/095646207782212252
更新日期:2007-11-01 00:00:00
abstract::Home treatment with podophyllotoxin or imiquimod are commonly prescribed therapies for anogenital warts. It is important to ascertain if patients are locating all lesions for treatment and if they know when they are clear of them. We set out to assess patients' ability to determine the number and location of their gen...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/095646240401500508
更新日期:2004-05-01 00:00:00
abstract::Global data on cervical lesion incidence and progression in HIV-positive women are essential for understanding the natural history of cervical neoplasia and informing screening policy. A systematic review was performed summarizing the incidence and progression of cervical lesions in HIV-positive women. Of 5882 HIV-pos...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章,评审
doi:10.1177/0956462413491735
更新日期:2014-03-01 00:00:00
abstract::A vaginal tampon specimen was previously shown to be suitable for the molecular diagnosis of non-ulcerative sexually transmitted infections (STIs). Different tampon fluid preparations were evaluated for the diagnosis of bacterial vaginosis (BV). Women with pregnancy related problems were enrolled. Two observers evalua...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/095646202760159693
更新日期:2002-08-01 00:00:00
abstract::We report a case of secondary syphilis mimicking lupus vulgaris in an HIV-infected patient. A 21-year-old Brazilian man presented with a two-month history of asymptomatic cutaneous lesions accompanied by fever and fatigue. Dermatological evaluation revealed an erythematous, crusted, large plaque on the neck with the '...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462418795590
更新日期:2018-12-01 00:00:00
abstract::There is still a paucity of research on the sociodemographic and other underlying factors associated with HIV transmission among women in India. This study was designed to investigate such factors in sexually experienced Indian women. We used data from the National Family Health Survey 3 (NFHS-3), which tested 52,853 ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2010.010127
更新日期:2011-03-01 00:00:00
abstract::Sub-Saharan Africa disproportionately represents the largest incidence of both HIV/AIDS and internal conflicts. The impact of conflict on HIV incidence is largely unknown. Current epidemiological evidence paradoxically suggests that in most populations affected by conflict, HIV prevalence is lower than surrounding com...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章,评审
doi:10.1258/095646206778691077
更新日期:2006-11-01 00:00:00
abstract::An innovative six-month, two sessions a week, funded clinical attachment programme was devised and introduced for practical training and experience to meet the demands and requirements of those wishing practical experience and training in genitourinary medicine. This has been generated by interest from previous theore...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462041211234
更新日期:2004-07-01 00:00:00
abstract::This study describes antimicrobial susceptibility patterns of Neisseria gonorrhoeae isolates obtained from female sex workers in Cotonou, Bénin. All isolates were susceptible to spectinomycin, ceftriaxone and ciprofloxacin, and susceptible to moderately susceptible to kanamycin; 9.8% of isolates were resistant to thia...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462011916848
更新日期:2001-02-01 00:00:00
abstract::The efficacy of oral azithromycin (500 mg daily for 10 days or 500 mg on alternate days for 11 days) in 100 patients with seropositive syphilis was studied. Clinical manifestations regressed more rapidly in azithromycin-treated patients compared with patients who received erythromycin or penicillin, and there was also...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462961917249
更新日期:1996-01-01 00:00:00
abstract::Genital elephantiasis (esthiomene), which is the dramatic end-result of lymphatic obstruction, is rather rare. Although mainly associated with filariasis and sexually transmitted diseases, such as lymphogranuloma venereum and donovanosis, it could also be an uncommon complication of tubercular lymphadenitis, a common ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/095646202760029886
更新日期:2002-06-01 00:00:00
abstract::Squamous cell carcinoma of the penis is an uncommon cancer, though in one study it accounted for 90% of all penile cancers. Its association with balanitis xerotica obliterans (BXO) is a rare though recognized occurrence. We describe a case of a 46-year-old Caucasian male who first presented to our open-access clinic w...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/095646206775455658
更新日期:2006-02-01 00:00:00
abstract::The British HIV Association (BHIVA) has published guidelines for immunization of HIV-infected adults. A chart review of 200 HIV-infected patients diagnosed was conducted to determine shortcomings in previous practice and determine which vaccines should routinely be given in specialist HIV clinics and which might be ab...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2011.011231
更新日期:2012-02-01 00:00:00
abstract::This unique report describes a fatal case of immune reconstitution syndrome associated with Kaposi's sarcoma (KS). This case also illustrates the possibility of cryptic visceral KS with minimal cutaneous disease, as well as the potential for differential responses of cutaneous and visceral KS to treatment. ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
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更新日期:2005-01-01 00:00:00
abstract::We report two cases who attended the genitourinary medicine clinic for the treatment of epididymo-orchitis. They did not respond to treatment and subsequent ultrasound sonography (USS) of testis confirmed microlithiasis and excluded any inflammatory process or carcinoma in situ. Because of its association with testicu...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2007.007184
更新日期:2008-04-01 00:00:00
abstract::This paper describes the incidence of sexually transmitted infections (STIs) recorded in the Weekly Returns Service (WRS) between 1994 and 2001. There were approximately 76,500 new diagnoses of STIs (7500 males, 71,000 females) and associated syndromes. Candidiasis was the commonest condition reported in males and fem...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/095646206780070992
更新日期:2006-10-01 00:00:00
abstract::A 46-year-old Caucasian heterosexual male was referred to a dedicated AIN clinic from colorectal multidisciplinary meeting (MDM) with AIN 3 following complete resection of anal squamous cell carcinoma (SCC). On further questioning, he revealed that he also had a lesion on his penis. Histology of the penile lesion demo...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2011.011255
更新日期:2012-04-01 00:00:00
abstract::Trichomonas vaginalis (TV) rates in women are increasing and many are asymptomatic. Nucleic acid amplification tests (NAATs) are becoming the 'gold standard' for diagnosis. We aimed to establish our asymptomatic TV rates by testing all women attending Oxfordshire's Sexual Health service, regardless of symptoms, using ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462416649888
更新日期:2017-03-01 00:00:00
abstract::Integrase strand transfer inhibitors (INSTIs) are a class of antiretroviral drugs with high virologic efficacy and excellent tolerability. Recent evidence showed a possible link of dolutegravir-based regimens with weight gain, and a relationship between raltegravir use and changes in adipose tissue density and metabol...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
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更新日期:2020-12-01 00:00:00
abstract::Risk factors for HIV infection in partners of HIV-seropositive index cases were investigated in a cross-sectional survey. Between September 1992 and April 1994 a total of 251 HIV-infected persons and 76 of their sexual partners were interviewed at the main sexually transmitted diseases (STDs) clinic in Trinidad. All p...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462981921918
更新日期:1998-03-01 00:00:00
abstract::The effect of low pH, normally present in the female genital tract, on HIV viability was examined. HIV is more acid stable than previously reported with no substantial reduction in infectivity occurring until pH levels are reduced below 4.5. The virucidal activity of 3 topical spermicides and chlorhexidine was assesse...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/095646249500600409
更新日期:1995-07-01 00:00:00
abstract::The prevalence of gonorrhoea and urogenital chlamydial infection was investigated in female prostitutes in Tegucigalpa, Honduras. Epidemiological data were recorded according to a standardized questionnaire. The median age of the prostitutes was 27 years and the median period of prostitution was 2-4 years. Most of the...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/095646249100200309
更新日期:1991-05-01 00:00:00
abstract::We examined the association between education and prevalent HIV-1 infection in the Rakai district, rural Uganda based on a cross-sectional analysis of a population-based cohort. In 1990, 1397 men and 1705 women aged 13 years and older, were enrolled in 31 randomly selected communities. Strata were comprised of main ro...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462991914456
更新日期:1999-07-01 00:00:00
abstract::The objective of the study was to compare the impact of oral and i.v. ganciclovir on resource use and direct health care costs, from the perspective of the UK National Health Service (NHS). The analytical framework used was cost analysis. The sources of data were an open, randomized clinical trial, and additional rese...
journal_title:International journal of STD & AIDS
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1258/0956462961918383
更新日期:1996-10-01 00:00:00