Treatment of syphilis with azithromycin.

Abstract:

:The efficacy of oral azithromycin (500 mg daily for 10 days or 500 mg on alternate days for 11 days) in 100 patients with seropositive syphilis was studied. Clinical manifestations regressed more rapidly in azithromycin-treated patients compared with patients who received erythromycin or penicillin, and there was also a more rapid reduction in serum antibody levels. In 90.3% of patients, the complete resolution of classic serological tests was observed within 4 months of completion of the azithromycin treatment. The immobilization (TPI) test and absorbed fluorescent treponema antibody tests became negative 12 months after treatment in 40% of patients. After 4 years of follow-up, no symptoms of neurosyphilis or syphilitic changes of visceral organs were observed.

journal_name

Int J STD AIDS

authors

Mashkilleyson AL,Gomberg MA,Mashkilleyson N,Kutin SA

doi

10.1258/0956462961917249

subject

Has Abstract

pub_date

1996-01-01 00:00:00

pages

13-5

eissn

0956-4624

issn

1758-1052

journal_volume

7 Suppl 1

pub_type

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