Abstract：
:Human umbilical cords were exposed to high amplitude focussed ultrasonic pulses with focal energy densities 0.6 and 0.4 mJ mm-2. The endothelium of the exposed vessel (vein) was examined by means of confocal laser scanning microscopy and scanning electron microscopy. The degree of tissue change ranged from the induction of stress fibres and intercellular gaps to the complete detachment of endothelial cells combined with damage of the basement membrane. An increased number of stress fibres may indicate an increased vessel wall permeability. This might explain the enhanced effects in experimental tumour therapy that have been found by other authors when combining shock-waves with drugs.
journal_name
Ultrasonicsjournal_title
Ultrasonicsauthors
Seidl M,Steinbach P,Wörle K,Hofstädter Fdoi
10.1016/0041-624x(94)90111-2subject
Has Abstractpub_date
1994-09-01 00:00:00pages
397-400issue
5eissn
0041-624Xissn
1874-9968pii
0041-624X(94)90111-2journal_volume
32pub_type
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