Toward gene therapy for growth hormone deficiency via salivary gland expression of growth hormone.

abstract：OBJECTIVE:To examine oral complications 6 months after modern radiation therapy (RT) for head and neck cancer (HNC). METHODS:Prospective multicenter cohort study of patients with HNC receiving intensity-modulated radiation therapy or more advanced RT. Stimulated whole salivary flow, maximal mouth opening, oral mucosit...

journal_title：Oral diseases

authors： Lalla RV,Treister N,Sollecito T,Schmidt B,Patton LL,Mohammadi K,Hodges JS,Brennan MT,OraRad Study Group.

更新日期：2017-11-01 00:00:00

abstract：OBJECTIVES:To use tissue engineering muscle repair (TEMR) for regenerating the lingual musculature of hemiglossectomized rats using neonatal myoblasts (NM) on porcine acellular urinary bladder matrix (AUBM). MATERIAL AND METHODS:The study used 80 male rats. A volumetric muscle loss (VML) injury was created on the left...

journal_title：Oral diseases

authors： Camacho-Alonso F,García-Carrillo N,Buendía AJ,Navarro JA,Peñarrocha-Oltra D,Peñarrocha-Diago M,Lacal-Luján J

更新日期：2020-10-08 00:00:00

abstract：UNLABELLED:The expression of the inducible nitric oxide synthase enzyme (iNOS) is a response to an inflammatory stimulus and produces a large amount of nitric oxide (NO), which may act as a cytotoxic molecule against the invading microorganism and may be related to both harmful and beneficial effects to tissues. OBJEC...

journal_title：Oral diseases

authors： Batista AC,Silva TA,Chun JH,Lara VS

更新日期：2002-09-01 00:00:00

abstract：OBJECTIVES:We aimed to investigate BRAF V600E percentage immunohistochemically in ameloblastomas of a single institute cohort. We were interested if age, location, histological properties, or tumor recurrence depend on the BRAF status. SUBJECTS, MATERIALS AND METHODS:We had 36 formalin-fixed, paraffin-embedded amelobl...

journal_title：Oral diseases

authors： Kelppe J,Thorén H,Ristimäki A,Haglund C,Sorsa T,Hagström J

更新日期：2019-05-01 00:00:00

abstract：OBJECTIVES:We examined the content of YouTube(™) videos on mouth (oral) cancer and evaluated their usefulness in promoting early detection of oral cancer. MATERIALS AND METHODS:A systematic search of YouTube(™) for videos containing information on mouth cancer was conducted using the keywords 'mouth cancer' and 'oral ...

journal_title：Oral diseases

authors： Hassona Y,Taimeh D,Marahleh A,Scully C

更新日期：2016-04-01 00:00:00

abstract：:As the AIDS pandemic has continued, our understanding of the events that occur during the entry and infection of conventional, susceptible cells has increased dramatically, leading to the development of control therapies for HIV-infected individuals. However, an ongoing hole in our understanding is how HIV crosses the...

journal_title：Oral diseases

authors： Moyes DL,Islam A,Kohli A,Naglik JR

更新日期：2016-04-01 00:00:00

abstract：:Oral Diseases (2011) 17, 252-257 Heme oxygenase (HO) system catabolizes heme into three products: carbon monoxide (CO), biliverdin/bilirubin and free iron, which consists of three forms identified to date: the oxidative stress-inducible protein HO-1 and the constitutive isozymes HO-2 and HO-3. HO has been involved in ...

journal_title：Oral diseases

authors： Fan W,Huang F,Zhu X,Li D,Fu S,He H

更新日期：2011-04-01 00:00:00

abstract：:Gastroesophageal reflux disease (GERD) is a common medical condition affecting approximately 35-40% of the adult population in the western world. The role of GERD in causing extra-esophageal symptoms including laryngitis, asthma, cough, chest pain, and dental erosions is increasingly recognized with renewed interest a...

journal_title：Oral diseases

authors： Farrokhi F,Vaezi MF

更新日期：2007-07-01 00:00:00

abstract：OBJECTIVES:To propose the application of the concept of geriatric syndrome for common geriatric oral and maxillofacial dysfunctions and to suggest the necessity of developing effective evaluation methods for oral and maxillofacial frailty. DESIGN:The concepts of frailty and geriatric syndrome based on multi-morbidity ...

journal_title：Oral diseases

authors： Nam Y,Kim NH,Kho HS

更新日期：2018-04-01 00:00:00

abstract：OBJECTIVE:Periodontitis is a chronic inflammatory disease of the tissues supporting the teeth and is caused by subgingival plaque. Systemic increases in reactive oxygen species are involved in pathogenesis of periodontitis. This study addressed the relationship between levels of serum oxidative stress and antibodies ag...

journal_title：Oral diseases

authors： Tamaki N,Hayashida H,Fukui M,Kitamura M,Kawasaki K,Nakazato M,Maeda T,Saito T,Ito HO

更新日期：2014-04-01 00:00:00

abstract：:With a history of over 2000 years, traditional Chinese medicine (TCM) evolves into a unique system of diagnosing and treating illnesses. It is a challenge to convey the fundamentals of this traditional medicine to our Western colleagues because of the differences in language, philosophy and concept of diagnosis and tr...

journal_title：Oral diseases

authors： Zheng LW,Hua H,Cheung LK

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVE:To develop a novel test for chronic ulcerative stomatitis (CUS), a chronic immunologically mediated condition that produces oral ulcerations. Current diagnostic methods require expensive and technically demanding in situ immunofluorescence (IF) studies. DESIGN:An Enzyme-Linked ImmunoSorbent Assay (ELISA) was...

journal_title：Oral diseases

authors： Solomon LW,Stark PC,Winter L,Kumar V,Sinha S

更新日期：2010-03-01 00:00:00

abstract：OBJECTIVE:The molecular mechanisms underlying the development of dysplasia in leukoplakia are unknown. We used RNA sequencing to examine the molecular and biological pathway differences in oral leukoplakia with and without oral epithelial dysplasia. MATERIALS AND METHODS:Excisional biopsy specimens (25) were taken fro...

journal_title：Oral diseases

authors： Farah CS,Fox SA

更新日期：2019-10-01 00:00:00

abstract：OBJECTIVE:In this study, we aimed to clarify the precise mechanism underlying lipopolysaccharide (LPS)-induced osteoclastogenesis in periodontal disease with a special reference to double-stranded RNA-dependent protein kinase (PKR). MATERIAL AND METHODS:We dissected the role of PKR in LPS-induced osteoclast differenti...

journal_title：Oral diseases

authors： Teramachi J,Inagaki Y,Shinohara H,Okamura H,Yang D,Ochiai K,Baba R,Morimoto H,Nagata T,Haneji T

更新日期：2017-03-01 00:00:00

abstract：AIM:The objective of this study was to investigate the effects of bisphosphonate on the mandible of rats in the growing phase with steroid-induced osteoporosis, and to estimate the biomechanical response in the mandibular bone. MATERIALS AND METHODS:Eight-week-old male Wistar rats (n = 50) were assigned to a 6-week co...

journal_title：Oral diseases

authors： Kimura E,Nishioka T,Hasegawa K,Maki K

更新日期：2007-11-01 00:00:00

abstract：OBJECTIVE:In this paper, we review the mechanisms thought to be involved in the activation of osteoclasts in periodontitis. SUMMARY:Osteoclasts are regulated by both microbial and host factors. Some factors act directly on cells of the osteoclast lineage, whereas others act indirectly through other cell types in the b...

journal_title：Oral diseases

authors： Wiebe SH,Hafezi M,Sandhu HS,Sims SM,Dixon SJ

更新日期：1996-06-01 00:00:00

abstract：:Hyaline ring granuloma (HRG) is a rare and atypical foreign-body granulomatous chronic inflammatory condition. Our aim was to make a critical review of the literature cases and also to illustrate histochemical and immunohistochemical findings of a new case. A modified PICO strategy was used. Inclusion criteria were me...

journal_title：Oral diseases

authors： Kimura TC,Carneiro MC,Coelho YFS,de Sousa SCOM,Veltrini VC

更新日期：2020-01-24 00:00:00

abstract：OBJECTIVES:The access to probiotics should be facilitated in order to encourage their usage. We evaluated the effect of consumption of two experimental probiotic-containing cheeses on the oral colonization of Candida in denture wearers. METHODS:Sixty denture wearers harboring oral Candida were randomly allocated in gr...

journal_title：Oral diseases

authors： Miyazima TY,Ishikawa KH,Mayer M,Saad S,Nakamae A

更新日期：2017-10-01 00:00:00

abstract：:Dental research over the last century has advanced our understanding of the etiology and pathogenesis of caries lesions. Increasing knowledge of the dynamic demineralization/remineralization processes has led to the current consensus that bacteria-mediated tooth destruction can be arrested or even to some degree rever...

journal_title：Oral diseases

authors： Aoba T

更新日期：2004-09-01 00:00:00

abstract：OBJECTIVE:To establish whether an intra-oral lubricating device for dry mouth alters the oral environment. DESIGN:A single-blind randomized cross-over study. METHOD:Twenty-nine dentate subjects from the Sjogren's syndrome clinic attended on five occasions at 4-week intervals. They were randomized, having the device f...

journal_title：Oral diseases

authors： Frost PM,Shirlaw PJ,Challacombe SJ,Fernandes-Naglik L,Walter JD,Ide M

更新日期：2006-01-01 00:00:00

abstract：:The salivary proteome consists of thousands of proteins, which include, among others, hormonal modulators of energy intake and output. Although the functions of this prominent category of hormones in whole body energy metabolism are well characterized, their functions in the oral cavity, whether as a salivary componen...

journal_title：Oral diseases

authors： Zolotukhin S

更新日期：2013-04-01 00:00:00

abstract：:HIV infection and AIDS are spreading rapidly among the world's children, especially among African-American and Hispanic children in the USA, and those in developing countries. Although recent research has identified several ways of preventing perinatal transmission of HIV, most of these methods are too expensive for w...

journal_title：Oral diseases

authors： Ramos-Gomez F

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVE:The management of the COVID-19 outbreak occurred in Lombardy (Italy) implied that non-COVID-19 health care was remodeled, limiting adequate resources in non-hospital public dental healthcare settings. This situation offered the opportunity to investigate the occupational COVID-19 risk to dental staff in publi...

journal_title：Oral diseases

authors： Nardone M,Cordone A,Petti S

更新日期：2020-09-03 00:00:00

abstract：OBJECTIVES:To test whether the submandibular/sublingual (SMSL) salivary secretion, mucin concentration and candida carriage status were altered in human immunodeficiency virus-positive (HIV+) patients. SUBJECTS AND METHODS:SMSL saliva collected from 48 HIV-infected and 31 HIV-negative men were analyzed for flow rates,...

journal_title：Oral diseases

authors： Jainkittivong A,Lin AL,Johnson DA,Langlais RP,Yeh CK

更新日期：2009-04-01 00:00:00

abstract：:Well into the fourth decade of the HIV/AIDS pandemic, we can look back on the early years, the initial discoveries, and the broad sweep of the progress of our understanding of the nature, causes, and significance of the oral lesions seen in those infected with the virus. Prominent among these is oral hairy leukoplakia...

journal_title：Oral diseases

authors： Greenspan JS,Greenspan D,Webster-Cyriaque J

更新日期：2016-04-01 00:00:00

abstract：OBJECTIVE:Non-syndromic cleft lip, with or without cleft palate (NSCL/P), is a common craniofacial birth defect, the risk of which is influenced from multiple genetic loci. Association study outcomes between single nucleotide polymorphisms (SNPs) near the muscle segment homeobox gene 1 (MSX1) and NSCL/P have been incon...

journal_title：Oral diseases

authors： Tasanarong P,Pabalan N,Tharabenjasin P,Jarjanazi H

更新日期：2019-09-01 00:00:00

abstract：:Cannabis, also known as marijuana, is one of the most commonly used substances for medical and recreational purposes globally. With the trend of global legalization of medical use of cannabis and even the recreational use, the prevalence of recreational use of cannabis has increased markedly over the past few years. C...

journal_title：Oral diseases

authors： Liu C,Qi X,Yang D,Neely A,Zhou Z

更新日期：2020-10-01 00:00:00

abstract：:Elder neglect (EN) is the failure of a designated caregiver to meet the needs of a dependent older person. World EN prevalence, meta-analyzed in this study, is 1.0% or 1.8% according to different statistical methods. Referring alleged EN cases to Adult Protective Services (APSs) by healthcare workers (HCWs) is mandato...

journal_title：Oral diseases

authors： Petti S

更新日期：2018-09-01 00:00:00

abstract：OBJECTIVES:Initial dental caries often occurs in clinic. Reduction of cariogenic bacteria and promotion of remineralization are effective ways to control them. This study was to develop bifunctional anticaries peptides with antibacterial and remineralizing properties. METHODS:We designed peptides TDH19, TNH19, and TVH...

journal_title：Oral diseases

authors： Wang X,Wang Y,Wang K,Ren Q,Li H,Zheng S,Niu Y,Zhou X,Li W,Zhang L

更新日期：2019-03-01 00:00:00

abstract：OBJECTIVES:This study aims to determine the diagnostic test accuracy (DTA) of hypermethylated DNA biomarkers in saliva and oral swabs for oral squamous cell carcinoma (OSCC) detection from the prevalidation studies available. MATERIALS AND METHODS:Electronic database searching of PubMed, EMBASE, Cochrane Library, Scop...

journal_title：Oral diseases

authors： Adeoye J,Alade AA,Zhu WY,Wang W,Choi SW,Thomson P

更新日期：2021-01-10 00:00:00