Abstract:
AIM:The objective of this study was to investigate the effects of bisphosphonate on the mandible of rats in the growing phase with steroid-induced osteoporosis, and to estimate the biomechanical response in the mandibular bone. MATERIALS AND METHODS:Eight-week-old male Wistar rats (n = 50) were assigned to a 6-week control (Co-6) group, 6-week steroid (St) group, 9-week control (Co-9) group, 9-week steroid + standard diet (StSD) group, or 9-week steroid + standard diet + bisphosphonate (StSDBp) group. The mandibular bone was evaluated by two-dimensional bone density measurement (PDS-15), three-dimensional pQCT, and quantitative analysis of Ca, P, Mg, and Zn using a sequential high frequency plasma spectrometer (ICPS-8000). RESULTS:In PDS-15 analysis, the bone density converted to aluminum equivalent was higher in StSDBp group when compared with the StSD group, and no significant difference was observed in bone density between St group and Co-6 group. In pQCT analysis, trabecular bone density and mineral content were significantly higher, while all other bone parameters were significantly lower in St group when compared with the Co-6 group. The densities of trabecular and cortical bones, mineral content and cross-sectional area of cortical bone, and non-invasive stress strain index with reference to x and yaxes were higher in StSDBp group than in StSD group. In quantitative analyses, Ca and P were markedly higher in StSDBp group than in StSD group, while there were no differences in Mg and Zn. CONCLUSION:Bisphosphonate treatment increases trabecular and cortical bone parameters in the mandible of growing rats with steroid-induced osteoporosis.
journal_name
Oral Disjournal_title
Oral diseasesauthors
Kimura E,Nishioka T,Hasegawa K,Maki Kdoi
10.1111/j.1601-0825.2006.01331.xsubject
Has Abstractpub_date
2007-11-01 00:00:00pages
544-9issue
6eissn
1354-523Xissn
1601-0825pii
ODI1331journal_volume
13pub_type
杂志文章相关文献
ORAL DISEASES文献大全abstract:OBJECTIVE:Mucoepidermoid carcinoma (MEC) is the most common malignant tumor of salivary glands with a widely diverse biologic behavior that is correlated with the histological grade of the tumor. The purpose of this study was to evaluate the clinical outcomes of MEC of minor salivary glands in a group of 16 patients, w...
journal_title:Oral diseases
pub_type: 杂志文章,评审
doi:10.1111/j.1601-0825.2005.01166.x
更新日期:2006-07-01 00:00:00
abstract:BACKGROUND:Oral-facial-digital syndrome (OFDS) type 1 (OFD1) is an X-linked dominant condition associated with embryonic male lethality. It almost always affects the oral cavity, face, and digits. It is considered to be a ciliopathy caused by mutations in the OFD1 gene. A variety of mutations have been described, and a...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/j.1601-0825.2011.01823.x
更新日期:2011-09-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to determine any association between anxiety and salivary cortisol levels in oral lichen planus (OLP) patients by the case-control method. DESIGN RELEVANT: Forty patients with OLP were evaluated. The OLP diagnosis was established through a composite of accepted clinical and histopath...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1034/j.1601-0825.2003.00960.x
更新日期:2003-11-01 00:00:00
abstract:OBJECTIVES:The aim of the study was to determine whether the expression levels of specific circulating serum microRNAs (miRNAs) are associated with mandibular prognathism (MP). METHODS:Sixty subjects in the early permanent dentition stage and 23 in the mixed dentition stage with MP were identified. Sixty-eight normal ...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/odi.12073
更新日期:2014-01-01 00:00:00
abstract:OBJECTIVE:Candida-induced denture stomatitis is a common debilitating problem among denture wearers. Previously, we described the fabrication of a new denture material that released antifungal drugs when immersed in phosphate buffered saline. Here, we use more clinically relevant immersion conditions (human saliva; 37°...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/odi.12456
更新日期:2016-07-01 00:00:00
abstract::A wide spectrum of oral lesions has been associated with human immunodeficiency viral infection (HIV), or AIDS. This report describes the case of an HIV-infected patient who developed a case of disseminated sporotrichosis whose first clinical sign was the presence of orofacial lesions. A histopathological study of thi...
journal_title:Oral diseases
pub_type: 杂志文章
doi:
更新日期:2001-03-01 00:00:00
abstract::The use of eponyms has long been contentious, but many remain in common use, as discussed elsewhere (Editorial: Oral Diseases. 2009: 15; 185). The use of eponyms in diseases of the head and neck is found mainly in specialties dealing with medically compromised individuals (paediatric dentistry, special care dentistry,...
journal_title:Oral diseases
pub_type: 历史文章,杂志文章,评审
doi:10.1111/j.1601-0825.2009.01538.x
更新日期:2009-11-01 00:00:00
abstract::Osteonecrosis of the jaw may be caused by radiation, medication, or infection. Optimal therapy requires a multimodal approach that combines surgery with adjuvant treatments. This review focuses on the use of adjunctive hyperbaric oxygen therapy for this condition. In addition to evidence regarding the basic and clinic...
journal_title:Oral diseases
pub_type: 杂志文章,评审
doi:10.1111/odi.12489
更新日期:2017-03-01 00:00:00
abstract:UNLABELLED:Autoimmune mechanisms may contribute to periodontal disease (PD) pathogenesis; autoantibody to collagen type 1 is produced at the periodontal site and local levels are found to be higher than in serum. OBJECTIVES:To find any evidence of autoimmune destruction in diseased periodontal tissues in patients with...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1046/j.1354-523x.2003.00961.x
更新日期:2004-03-01 00:00:00
abstract:OBJECTIVES:To investigate practices and opinions of general dentists in Maryland, USA, related to oral and pharyngeal cancer prevention and early detection. DESIGN AND METHODS:A pre-tested, 34-item questionnaire, cover letter and addressed, stamped envelope were mailed in the summer, 1995, to a simple random sample of...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/j.1601-0825.2000.tb00140.x
更新日期:2000-09-01 00:00:00
abstract:OBJECTIVES:To find out if strontium is incorporated into plaque and enamel in vivo during a 2-week rinsing period with a chlorhexidine-fluoride-strontium solution and to determine the effects of the rinsing on the numbers of mutans streptococci and lactobacilli in plaque. SUBJECTS AND METHODS:A total of 18 adult parti...
journal_title:Oral diseases
pub_type: 临床试验,杂志文章
doi:10.1111/j.1601-0825.1998.tb00267.x
更新日期:1998-06-01 00:00:00
abstract:OBJECTIVES:To determine expression and localization of membrane-associated mucins within human keratinized and non-keratinized oral epithelia, and to explore transcriptional changes associated with primary Sjögren's syndrome. SUBJECTS AND METHODS:Mucin transcripts and glycoproteins were determined by RT-PCR and immuno...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/odi.13098
更新日期:2019-07-01 00:00:00
abstract:OBJECTIVE:To assess whether a relationship existed between the T102C polymorphism of 5-HT2A receptor gene and temporomandibular dysfunction. METHODS:Sixty-three patients with temporomandibular dysfunction, and 54 healthy volunteer controls were included in the study. Molecular analysis of the T102C polymorphism of the...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/j.1601-0825.2004.01037.x
更新日期:2004-11-01 00:00:00
abstract::Head and neck squamous cell carcinoma (HNSCC) is one of the most morbid, mortal, and genetically diverse malignancies. Although HNSCC is heterogeneous in nature, alterations in major components of the PI3K/Akt/mTOR pathway are consistently observed throughout the majority of HNSCC cases. These alterations include gene...
journal_title:Oral diseases
pub_type: 杂志文章,评审
doi:10.1111/odi.12206
更新日期:2015-10-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to compare the oral health status of chronic renal failure (CRF) patients on renal replacement therapy with a matched reference population. DESIGN:Cross-sectional study. SUBJECTS:Forty-two dentate CRF patients--aged 25-52 years old--were matched with a reference group of 808 dentat...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/j.1601-0825.2005.01183.x
更新日期:2006-03-01 00:00:00
abstract:OBJECTIVES:Initial dental caries often occurs in clinic. Reduction of cariogenic bacteria and promotion of remineralization are effective ways to control them. This study was to develop bifunctional anticaries peptides with antibacterial and remineralizing properties. METHODS:We designed peptides TDH19, TNH19, and TVH...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/odi.12990
更新日期:2019-03-01 00:00:00
abstract:AIM:To investigate prospectively the qualitative and quantitative changes in oral carriage of yeasts and coliforms in southern Chinese people suffering from stroke. MATERIALS AND METHODS:In 56 elderly people suffering from stroke in a rehabilitation unit of a general medical hospital in Hong Kong, oral microbiological...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/j.1601-0825.2006.01347.x
更新日期:2008-01-01 00:00:00
abstract:OBJECTIVE:We investigated the relationship amongst the oral mucosal bacterial community, clinical severity and inflammatory markers in the two most common immune-mediated oral mucosal diseases, namely recurrent aphthous stomatitis (RAS) and oral lichen planus (LP). METHODS:Patients with RAS (n = 15) and LP (n = 18) an...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/odi.13420
更新日期:2020-10-01 00:00:00
abstract:BACKGROUND:The purposes of this study were to assess the influence of age on oral squamous cell carcinoma patients and sought to analyze the reasons that may contribute to this difference. METHODS:This study enrolled 2,782 patients included 2,443 patients in a retrospective cohort to find the influence of age and 339 ...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/odi.13015
更新日期:2019-04-01 00:00:00
abstract:OBJECTIVE:To assess tissue characterization relating with neck metastasis of invasive tongue cancer, we investigate the usefulness of intra-oral ultrasonography (US). MATERIALS AND METHODS:The patients with squamous cell carcinoma of the tongue (n = 110) were preoperatively evaluated with intra-oral US. The US images ...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/j.1601-0825.2007.01423.x
更新日期:2008-10-01 00:00:00
abstract::Next-generation sequencing (NGS) has revolutionized the field of genomics and improved our understanding of cancer biology. Advances have been achieved by sequencing tumor DNA and using matched normal DNA to filter out germ line variants to identify cancer-specific changes. The identification of high incidences of act...
journal_title:Oral diseases
pub_type: 杂志文章,评审
doi:10.1111/odi.12246
更新日期:2015-01-01 00:00:00
abstract::The traditional concept of caries as a multifactorial transmittable and infectious disease has been challenged. Novel conceptual ideas have come to add to the complexity of this highly prevalent disease worldwide. Current etiological understanding of the disease has emphasized the pivotal role of sugars in caries. In ...
journal_title:Oral diseases
pub_type: 杂志文章,评审
doi:10.1111/odi.12778
更新日期:2018-10-01 00:00:00
abstract:OBJECTIVES:YouTube™ has become a widely used source of health information. This cross-sectional study aimed to analyze the quality of English language videos on oral leukoplakia available on YouTube™. MATERIALS AND METHODS:A YouTube™ search for oral leukoplakia was performed, leading to 1,690 videos. The first 100 res...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/odi.13161
更新日期:2019-11-01 00:00:00
abstract:OBJECTIVES:To prospectively examine the association of cigarette smoking and alcohol drinking with oral and pharyngeal carcinogenesis, we analyzed data from a nation-wide large-scale cohort study in Japan. METHODS:A total of 34 136 men and 43 711 women aged 40-79 years were included in the study. The Cox proportional ...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/j.1601-0825.2007.01378.x
更新日期:2008-05-01 00:00:00
abstract:OBJECTIVE:Oral healthcare professionals are frequently confronted with patients using drugs on a daily basis. These drugs can cause taste disorders as adverse effect. The literature that discusses drug-induced taste disorders is fragmented. This article aims to support oral healthcare professionals in their decision ma...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/odi.13199
更新日期:2020-01-01 00:00:00
abstract:OBJECTIVES:This 6-month prospective clinical study assessed the impacts of Invisalign appliances on the oral bacterial community and oral health of patients. METHODS:Salivary samples were obtained from twenty-five adult patients receiving Invisalign aligner treatment before the treatment (Group B) and at a 6-month fol...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/odi.13175
更新日期:2020-03-01 00:00:00
abstract:OBJECTIVES:To comparatively assess periodontal status in patients who chew different products and patients who do not have this habit and to assess how this practice interacts with predisposing factors and risk indicators of disease. METHODS:Patients included in the dental care carried out in a rural community in Indi...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/odi.12820
更新日期:2018-07-01 00:00:00
abstract:OBJECTIVE:The molecular mechanisms underlying the development of dysplasia in leukoplakia are unknown. We used RNA sequencing to examine the molecular and biological pathway differences in oral leukoplakia with and without oral epithelial dysplasia. MATERIALS AND METHODS:Excisional biopsy specimens (25) were taken fro...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/odi.13156
更新日期:2019-10-01 00:00:00
abstract:OBJECTIVE:Prevotella intermedia has been reported to be associated with periodontal disease whilst P. nigrescens has predominantly been isolated from more specific conditions and healthy sites. The aim of the present study was to compare the enzyme activity of these species. MATERIALS AND METHODS:Nine strains of P. in...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/j.1601-0825.1996.tb00237.x
更新日期:1996-12-01 00:00:00
abstract:OBJECTIVES:To use tissue engineering muscle repair (TEMR) for regenerating the lingual musculature of hemiglossectomized rats using neonatal myoblasts (NM) on porcine acellular urinary bladder matrix (AUBM). MATERIAL AND METHODS:The study used 80 male rats. A volumetric muscle loss (VML) injury was created on the left...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/odi.13674
更新日期:2020-10-08 00:00:00