Dysplastic oral leukoplakia is molecularly distinct from leukoplakia without dysplasia.

abstract：:In order for chairside diagnostic testing to make an impact on dental therapy, practitioners require a better understanding of genetic mutations contributing to the pathophysiology of periodontal disease. Commensal and pathogenic bacterial colonization in oral cavity tissues produces a cascade of proinflammatory signa...

journal_title：Oral diseases

authors： Rudick CP,Lang MS,Miyamoto T

更新日期：2019-11-01 00:00:00

abstract：OBJECTIVE:Patients with burning mouth syndrome (BMS) often represent a clinical challenge as available agents for symptomatic treatment are few and often ineffective. The aim was to evaluate the effect of a bupivacaine lozenge on oral mucosal pain, xerostomia, and taste alterations in patients with BMS. METHODS:Eighte...

journal_title：Oral diseases

authors： Treldal C,Jacobsen CB,Mogensen S,Rasmussen M,Jacobsen J,Petersen J,Lynge Pedersen AM,Andersen O

更新日期：2016-03-01 00:00:00

abstract：:The use of eponyms has long been contentious, but many remain in common use, as discussed elsewhere (Editorial: Oral Diseases. 2009: 15; 185). The use of eponyms in diseases of the head and neck is found mainly in specialties dealing with medically compromised individuals (paediatric dentistry, special care dentistry,...

journal_title：Oral diseases

authors： Scully C,Langdon J,Evans J

更新日期：2009-11-01 00:00:00

abstract：OBJECTIVES:Salivary glands are useful target organs for local and systemic gene therapeutics. For such applications, the regulation of transgene expression is important. Previous studies by us in murine submandibular glands showed that a rapamycin transcriptional regulation system in a single serotype 2, adeno-associat...

journal_title：Oral diseases

authors： Zheng C,Voutetakis A,Metzger M,Afione S,Cotrim AP,Eckhaus MA,Rivera VM,Clackson T,Chiorini JA,Donahue RE,Dunbar CE,Baum BJ

更新日期：2010-04-01 00:00:00

abstract：OBJECTIVE:Placenta growth factor (PlGF) is associated with the progression and prognosis of oral cancer. MATERIALS AND METHODS:This study used ELISA, quantitative polymerase chain reaction, and Western blotting to study the arecoline-stimulated (PlGF) protein or mRNA expression in human gingival epithelial S-G cells. ...

journal_title：Oral diseases

authors： Cheng SJ,Ko HH,Cheng SL,Lee JJ,Chen HM,Chang HH,Kok SH,Kuo MY,Chiang CP

更新日期：2013-07-01 00:00:00

abstract：OBJECTIVES:Initial dental caries often occurs in clinic. Reduction of cariogenic bacteria and promotion of remineralization are effective ways to control them. This study was to develop bifunctional anticaries peptides with antibacterial and remineralizing properties. METHODS:We designed peptides TDH19, TNH19, and TVH...

journal_title：Oral diseases

authors： Wang X,Wang Y,Wang K,Ren Q,Li H,Zheng S,Niu Y,Zhou X,Li W,Zhang L

更新日期：2019-03-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to compare viscosity and wettability between animal mucin solutions and human saliva. MATERIALS AND METHODS:Human whole and glandular saliva, porcine gastric mucin, bovine submaxillary mucin, and a mucin-based saliva substitute were used. Viscosity was measured with a cone-and-p...

journal_title：Oral diseases

authors： Park MS,Chung JW,Kim YK,Chung SC,Kho HS

更新日期：2007-03-01 00:00:00

abstract：BACKGROUND:Differences in genotype and phenotype of detoxification genes could be one reason for conflicting results in studies dealing with gene polymorphisms as susceptibility factors for tobacco associated cancer. OBJECTIVES:The objective of this study was to investigate gene polymorphisms of detoxification enzymes...

journal_title：Oral diseases

authors： Gronau S,Koenig-Greger D,Jerg M,Riechelmann H

更新日期：2003-03-01 00:00:00

abstract：OBJECTIVE:To determine the clinical diagnostic accuracy of Narrow Band Imaging(™) for the detection of oral potentially malignant disorders in a prospective series of patients. MATERIALS AND METHODS:New and existing patients referred to an oral medicine and pathology specialist clinic for assessment of at least one wh...

journal_title：Oral diseases

authors： Vu AN,Matias M,Farah CS

更新日期：2015-05-01 00:00:00

abstract：AIM:The present study aimed to monitor the clinical outcomes and the metabolic response of periodontal therapy (non-surgical) in patients with periodontitis (chronic) and uncontrolled diabetes (type 2). METHODS:Eighty-eight subjects with periodontitis (chronic) and uncontrolled diabetes (type 2) were enrolled in this ...

journal_title：Oral diseases

authors： El-Makaky Y,Shalaby HK

更新日期：2020-05-01 00:00:00

abstract：OBJECTIVES:The imbalanced host response in front of a dysbiotic biofilm is one of the major aspects of severe periodontitis, which also presents a strong familial aggregation related to the susceptibility factors transmission within family members. This study hypothesized that aggressive periodontitis (GAgP) patients a...

journal_title：Oral diseases

authors： Monteiro MF,Casati MZ,Sallum EA,Silvério KG,Nociti-Jr FH,Casarin RCV

更新日期：2020-11-30 00:00:00

abstract：OBJECTIVE:Head and neck squamous cell carcinoma (HNSCC) progression and metastasis have previously been associated with the activation of phosphatidylinositol 3-kinase-protein kinase B (PI3K-Akt) and Wnt signalling pathways, which lead to the activation of pro-proliferative genes, such as cyclin D1. The current study a...

journal_title：Oral diseases

authors： Sales KU,Giudice FS,Castilho RM,Salles FT,Squarize CH,Abrahao AC,Pinto DS Jr

更新日期：2014-04-01 00:00:00

abstract：OBJECTIVE:To assess whether a relationship existed between the T102C polymorphism of 5-HT2A receptor gene and temporomandibular dysfunction. METHODS:Sixty-three patients with temporomandibular dysfunction, and 54 healthy volunteer controls were included in the study. Molecular analysis of the T102C polymorphism of the...

journal_title：Oral diseases

authors： Mutlu N,Erdal ME,Herken H,Oz G,Bayazit YA

更新日期：2004-11-01 00:00:00

abstract：:Dental research over the last century has advanced our understanding of the etiology and pathogenesis of caries lesions. Increasing knowledge of the dynamic demineralization/remineralization processes has led to the current consensus that bacteria-mediated tooth destruction can be arrested or even to some degree rever...

journal_title：Oral diseases

authors： Aoba T

更新日期：2004-09-01 00:00:00

abstract：OBJECTIVE:To document the pattern of intra-oral carcinomas diagnosed in north-eastern Nigeria. DESIGN AND SETTING:A retrospective clinical and histopathological review seen in a tertiary care hospital (January 1987-December 2002). MATERIALS AND METHODS:Information on socio-demographic characteristics of patients and ...

journal_title：Oral diseases

authors： Otoh EC,Johnson NW,Olasoji HO,Danfillo IS,Adeleke OA

更新日期：2005-11-01 00:00:00

abstract：OBJECTIVE:Orofacial granulomatosis (OFG) is a rare condition characterized by non-caseating granulomas in the orofacial region. Protease-Activated Receptors (PARs) play a role in inflammatory diseases in diverse human tissues. The aim of the study was to investigate the expression of PAR-1, PAR-2, MMP-2, MMP-9, COX-1, ...

journal_title：Oral diseases

authors： Ketabchi S,Massi D,Ficarra G,Rubino I,Franchi A,Paglierani M,Simoni A,Capodiferro S,Favia G,Maiorano E,Tarantini F,Cirino G,Santucci M

更新日期：2007-07-01 00:00:00

abstract：OBJECTIVE:To investigate the clinicopathological characteristics and biologic behaviour of epithelioid hemangioendothelioma in the oral cavity. MATERIALS AND METHODS:The clinical features and pathological findings of nine cases with intraoral epithelioid hemangioendothelioma were reviewed, including immunohistochemist...

journal_title：Oral diseases

authors： Sun ZJ,Zhang L,Zhang WF,Chen XM,Lai FM,Zhao YF

更新日期：2007-03-01 00:00:00

abstract：OBJECTIVE:Subjects with cleft lip and palate (CLP) present high prevalence of dental agenesis. Among candidate genes for these phenotypes is IRF6. However, genetic studies do not analyze dental agenesis as a phenotype associated with cleft. Therefore, we investigated the frequency of rare and novel variations in IRF6 i...

journal_title：Oral diseases

authors： Neves LT,Dionísio TJ,Garbieri TF,Parisi VA,Oliveira FV,Oliveira TM,Santos CF

更新日期：2019-01-01 00:00:00

abstract：:Orofacial granulomatosis (OFG) is the presence of persistent enlargement of the soft tissues of the oral and maxillofacial region, characterized by non-caseating granulomatous inflammation in the absence of diagnosable systemic Crohn's disease (CD) or sarcoidosis. Over 20 years have passed since OFG was first describe...

journal_title：Oral diseases

authors： Grave B,McCullough M,Wiesenfeld D

更新日期：2009-01-01 00:00:00

abstract：:The traditional concept of caries as a multifactorial transmittable and infectious disease has been challenged. Novel conceptual ideas have come to add to the complexity of this highly prevalent disease worldwide. Current etiological understanding of the disease has emphasized the pivotal role of sugars in caries. In ...

journal_title：Oral diseases

authors： Giacaman RA

更新日期：2018-10-01 00:00:00

abstract：:Osteonecrosis of the jaw may be caused by radiation, medication, or infection. Optimal therapy requires a multimodal approach that combines surgery with adjuvant treatments. This review focuses on the use of adjunctive hyperbaric oxygen therapy for this condition. In addition to evidence regarding the basic and clinic...

journal_title：Oral diseases

authors： Ceponis P,Keilman C,Guerry C,Freiberger JJ

更新日期：2017-03-01 00:00:00

abstract：OBJECTIVE:The present study summarizes the current knowledge on the role of bacterial extracellular signaling systems, known as quorum sensing (QS), in oral biofilm formation, and on the possibility of blocking these microbial communication systems as a potential approach to prevent and treat oral infectious diseases. ...

journal_title：Oral diseases

authors： Muras A,Mallo N,Otero-Casal P,Pose-Rodríguez JM,Otero A

更新日期：2020-10-20 00:00:00

abstract：BACKGROUND:Oral-facial-digital syndrome (OFDS) type 1 (OFD1) is an X-linked dominant condition associated with embryonic male lethality. It almost always affects the oral cavity, face, and digits. It is considered to be a ciliopathy caused by mutations in the OFD1 gene. A variety of mutations have been described, and a...

journal_title：Oral diseases

authors： Diz P,Alvarez-Iglesias V,Feijoo JF,Limeres J,Seoane J,Tomás I,Carracedo A

更新日期：2011-09-01 00:00:00

abstract：:Proliferative verrucous leukoplakia (PVL) is of uncertain etiology but may be associated with human papillomavirus (HPV) infection. Proliferative verrucous leukoplakia is seen mainly in older women, beginning as a simple slow-growing, persistent leukoplakia that tends to spread and become multifocal and affect the gin...

journal_title：Oral diseases

authors： Bagan J,Scully C,Jimenez Y,Martorell M

更新日期：2010-05-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to evaluate the erosive/abrasive enamel wear after contact with orange juices modified with different dietary supplements. METHODS:A total of 96 bovine enamel samples were prepared and allocated to eight groups (1-8; n = 12). Samples were eroded (120 s) in 200 ml of the following ei...

journal_title：Oral diseases

authors： Wegehaupt F,Günthart N,Sener B,Attin T

更新日期：2011-07-01 00:00:00

abstract：OBJECTIVES:To determine glucose transporter 1 (GLUT1) and runt-related transcription factor 2 (RUNX2) expression during reparative dentinogenesis after pulpotomy with mineral trioxide aggregate (MTA) capping. SUBJECTS AND METHODS:Eight-week-old male Wistar rats were used. Pulp of the upper left first molar was exposed...

journal_title：Oral diseases

authors： Takeuchi R,Ohkura N,Yoshiba K,Tohma A,Yoshiba N,Edanami N,Shirakashi M,Belal RS,Ohshima H,Noiri Y

更新日期：2020-03-01 00:00:00

abstract：:The combination of Moebius and Poland anomalies is rarely described in the literature. While some authors believe this association is an independent syndrome, others think that Poland, Moebius and Poland-Moebius syndromes are variations of the same condition. We report a case of Poland-Moebius syndrome in a 6-year-old...

journal_title：Oral diseases

authors： Domingos AC,Lopes SL,Almeida SM,Boscolo FN,Whaites EJ

更新日期：2004-11-01 00:00:00

abstract：OBJECTIVE:To explore the type and prevalence of oral mucosal lesions among adults with primary HIV infection (PHI) compared with HIV-negative adults at high risk for HIV disease, and in relation to HIV viral load. METHODS:We conducted standardized oral examinations to identify specific oral mucosal lesions among adult...

journal_title：Oral diseases

authors： Owotade FJ,Shiboski CH,Poole L,Ramstead CA,Malvin K,Hecht FM,Greenspan JS

更新日期：2008-09-01 00:00:00

abstract：OBJECTIVES:A multicentre collaborative study by the London HIV and Dentistry Group failed to associate the presence of erythematous candidiasis (EC) with advanced HIV disease. Data from a study of the periodontal health of homosexual men attending a genito-urinary medicine clinic presented an opportunity to investigate...

journal_title：Oral diseases

authors： Robinson PG,Challacombe SJ,Sheiham A,Zakrzewska JM

更新日期：1997-05-01 00:00:00

abstract：OBJECTIVE:To detail a scoping review on the global and regional relative frequencies of oral mucosal disorders in the children based on both clinical studies and those reported from biopsy records. MATERIALS AND METHODS:A literature search was completed from 1 January 1990 to 31 December 2018 using PubMed and EMBASE. ...

journal_title：Oral diseases

authors： Hong CHL,Dean DR,Hull K,Hu SJ,Sim YF,Nadeau C,Gonçalves S,Lodi G,Hodgson TA

更新日期：2019-06-01 00:00:00