Genetic and physiological studies of abortive infections of hydroxymethyluracil-containing bacteriophages in lysogens of temperate Bacillus subtilis bacteriophage SPO2.

abstract：:We have demonstrated that Epstein-Barr virus (EBV) confers enhanced growth capability in soft agarose, tumorigenesis in the SCID mouse, and resistance to apoptosis in the Burkitt's lymphoma cell line Akata. Subsequently, we have shown that EBV-encoded small RNAs (EBERs) are responsible for these phenotypes. We constan...

journal_title：Journal of virology

authors： Komano J,Takada K

更新日期：2001-02-01 00:00:00

abstract：:During lytic infection, herpes simplex virus subverts the host cell RNA polymerase II transcription machinery to efficiently express its own genome while repressing the expression of most cellular genes. The mechanism by which RNA polymerase II is directed to the viral delayed-early and late genes is still unresolved....

journal_title：Journal of virology

authors： Rice SA,Long MC,Lam V,Spencer CA

更新日期：1994-02-01 00:00:00

abstract：:The fundamental event in prion disease is thought to be the posttranslational conversion of the cellular prion protein (PrPC) into a pathogenic isoform (PrPSc). The occurrence of PrPC on the cell surface and PrPSc in amyloid plaques in situ or in aggregates following purification complicates the study of the molecular...

journal_title：Journal of virology

authors： Williamson RA,Peretz D,Pinilla C,Ball H,Bastidas RB,Rozenshteyn R,Houghten RA,Prusiner SB,Burton DR

更新日期：1998-11-01 00:00:00

abstract：:BALB/c mice treated with pristane and Abelson virus have been used as an animal model system for the rapid induction of plasmacytomas. Myelomonocytic tumors with helper Moloney murine leukemia virus clonally inserted into the c-myb locus were observed in about 10% of pristane-primed BALB/c mice infected with Abelson v...

journal_title：Journal of virology

authors： Shen-Ong GL,Wolff L

更新日期：1987-12-01 00:00:00

abstract：UNLABELLED:PD-1 is an inhibitory receptor that has a major role in T cell dysfunction during chronic infections and cancer. While demethylation of the PD-1 promoter DNA is observed in exhausted T cells isolated from chronically infected individuals, little is known about when this stable demethylation of PD-1 promoter ...

journal_title：Journal of virology

authors： Ahn E,Youngblood B,Lee J,Lee J,Sarkar S,Ahmed R

更新日期：2016-09-12 00:00:00

abstract：:Upon immunization and restimulation with tumors induced by the endogenous AKR/Gross murine leukemia virus (MuLV), C57BL/6 mice generate vigorous H-2K(b)-restricted cytotoxic T-lymphocyte (CTL) responses to a determinant (KSPWFTTL) derived from the p15E transmembrane portion of the viral envelope glycoprotein. By contr...

journal_title：Journal of virology

authors： Kim V,Yewdell JW,Green WR

更新日期：2000-04-01 00:00:00

abstract：:The expression of Marek's disease virus (MDV) transcripts and protein products was investigated in reticuloendotheliosis virus-transformed avian T-lymphoblastoid cell line RECC-CU91, which was superinfected with MDV. The presence of MDV in the superinfected cell line, renamed RECC-CU210, was demonstrated by Southern h...

journal_title：Journal of virology

authors： Pratt WD,Morgan RW,Schat KA

更新日期：1992-12-01 00:00:00

abstract：:Mouse mammary tumor virus (MTV) was isolated from the milk of RIII mice by density-gradient centrifugation in Ficoll. The homogeneity of the preparation was demonstrated in electron micrographs. The nucleic acid was extracted with phenol in the presence of Pronase. Its viral origin was attested by failure of ribo-nucl...

journal_title：Journal of virology

authors： Sarkar NH,Moore DH

更新日期：1970-02-01 00:00:00

abstract：:Mice and cattle injected with plasmids encoding bovine herpesvirus 1 (BHV-1) glycoproteins developed gene-specific antibody responses capable of neutralizing BHV-1. The ability of animals to respond serologically to DNA injections was in part dependent on the quantity of DNA injected and was also negatively affected b...

journal_title：Journal of virology

authors： Cox GJ,Zamb TJ,Babiuk LA

更新日期：1993-09-01 00:00:00

abstract：:Previous experiments have demonstrated that adenovirus infection of human and mouse cells leads to an E1A-dependent activation of the DNA-binding capacity of a cellular transcription factor termed E2F. E2F binds to two sites in the adenovirus E2 early promoter which have been shown to be critical for E1A-dependent E2 ...

journal_title：Journal of virology

authors： Reichel R,Neill SD,Kovesdi I,Simon MC,Raychaudhuri P,Nevins JR

更新日期：1989-09-01 00:00:00

abstract：:The parechoviruses differ in many biological properties from other picornaviruses, and their replication strategy is largely unknown. In order to identify the viral RNA replication complex in human parechovirus type 1 (HPEV-1)-infected cells, we located viral protein and RNA in correlation to virus-induced membrane al...

journal_title：Journal of virology

authors： Krogerus C,Egger D,Samuilova O,Hyypiä T,Bienz K

更新日期：2003-08-01 00:00:00

abstract：:Inbred LSH hamster brain cells were transformed in vitro by the GS strain of BK virus (BKV), and transplantable tumors classified as undifferentiated glioblastomas were induced in the syngeneic host. The viral status in the transformed cells, designated LSH-BR-BK, was established. About 46 genome equivalents per cell ...

journal_title：Journal of virology

authors： Beth E,Giraldo G,Schmidt-Ullrich R,Pater MM,Pater A,di Mayorca G

更新日期：1981-10-01 00:00:00

abstract：:MVL2, an enveloped double-stranded DNA mycoplasmavirus, causes a nonlytic infection of Acholeplasma laidlawii leading to the establishment of a persistent infection. Persistently infected clones were found to be resistant to superinfection by homologous virus, but could be infected by heterologous virus. Cells in a pe...

journal_title：Journal of virology

authors： Putzrath RM,Maniloff J

更新日期：1978-10-01 00:00:00

abstract：:Several domains of CD4 have been suggested to play a critical role in events that follow its binding to the human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein (gp120-gp41). It has been reported previously that cells expressing a chimeric molecule consisting of the first 177 residues of human CD4 attache...

journal_title：Journal of virology

authors： Golding H,Blumenthal R,Manischewitz J,Littman DR,Dimitrov DS

更新日期：1993-11-01 00:00:00

abstract：:Passive transfer of neutralizing antibodies is effective in protecting rhesus macaques against simian/human immunodeficiency virus (SHIV) challenge. In addition to neutralization, effector functions of the crystallizable fragment (Fc) of antibodies are involved in antibody-mediated protection against a number of virus...

journal_title：Journal of virology

authors： Moldt B,Schultz N,Dunlop DC,Alpert MD,Harvey JD,Evans DT,Poignard P,Hessell AJ,Burton DR

更新日期：2011-10-01 00:00:00

abstract：:Picornavirus RNAs are uncapped messengers and have unusually long 5' nontranslated regions (5'NTRs) which contain many noninitiating AUG triplets. The translational efficiency of different picornavirus RNAs varies between different cell-free extracts and even in the same extract, such as micrococcal nuclease-treated r...

journal_title：Journal of virology

authors： Jang SK,Kräusslich HG,Nicklin MJ,Duke GM,Palmenberg AC,Wimmer E

更新日期：1988-08-01 00:00:00

abstract：:Recent studies of varicella-zoster virus (VZV) DNA sequence variation, involving large numbers of globally distributed clinical isolates, suggest that this virus has diverged into at least three distinct genotypes designated European (E), Japanese (J), and mosaic (M). In the present study, we determined and analyzed t...

journal_title：Journal of virology

authors： Norberg P,Liljeqvist JA,Bergström T,Sammons S,Schmid DS,Loparev VN

更新日期：2006-10-01 00:00:00

abstract：:Maintenance of Kaposi's sarcoma-associated herpesvirus (KSHV) latent infection depends on the viral episomes in the nucleus being distributed to daughter cells following cell division. The latency-associated nuclear antigen (LANA) is constitutively expressed in all KSHV-infected cells. LANA binds sequences in the term...

journal_title：Journal of virology

authors： Krithivas A,Fujimuro M,Weidner M,Young DB,Hayward SD

更新日期：2002-11-01 00:00:00

abstract：:The genome of infectious bursal disease virus consists of two segments of double-stranded RNA of 2.5 X 10(6) and 2.2 X 10(6) molecular weight. Polyacrylamide gel electrophoresis of purified virus resolved four structural polypeptides: VP-1 (90,000), VP-2 (41,000), VP-3 (35,000), and VP-4 (28,000). Peptide map comparis...

journal_title：Journal of virology

authors： Dobos P

更新日期：1979-12-01 00:00:00

abstract：:Second-site revertants from replication-incompetent molecular clones of human immunodeficiency virus (HIV) contain base substitutions adjacent to the TATA motif. The altered TATA box motifs were analyzed for their effect(s) on virus infectivity, long terminal repeat (LTR)-directed expression in transient transfection ...

journal_title：Journal of virology

authors： Kashanchi F,Shibata R,Ross EK,Brady JN,Martin MA

更新日期：1994-05-01 00:00:00

abstract：:We have developed a system in which vesicular stomatitis virus (VSV) minigenomes encoding viral structural proteins can be expressed from plasmids. These RNAs can be replicated, transcribed, and packaged into infectious particles when coexpressed with the other VSV proteins. The minigenomes contain either the glycopro...

journal_title：Journal of virology

authors： Stillman EA,Rose JK,Whitt MA

更新日期：1995-05-01 00:00:00

abstract：:The proline-rich tandem repeat domain of human mucin MUC1 forms an extended structure containing large repeating loops that are crested by a turn. We show that the repeating-loop structure of MUC1 can be replaced by an antibody complementarity-determining region loop of a human immunodeficiency virus type 1 (HIV-1)-sp...

journal_title：Journal of virology

authors： Fontenot JD,Zacharopoulos VR,Phillips DM

更新日期：1996-10-01 00:00:00

abstract：UNLABELLED:Virus-like particles (VLPs) built on the Newcastle disease virus (NDV) core proteins, NP and M, and containing two chimeric proteins, F/F and H/G, composed of respiratory syncytial virus (RSV) fusion protein (F) and glycoprotein (G) ectodomains fused to the transmembrane and cytoplasmic domains of the NDV F ...

journal_title：Journal of virology

authors： McGinnes Cullen L,Schmidt MR,Kenward SA,Woodland RT,Morrison TG

更新日期：2015-07-01 00:00:00

abstract：:The role of the influenza A virus panhandle structure formed from the 3'- and 5'-terminal nucleotides of virion RNA segments was studied in both an RNA polymerase binding assay and an in vitro transcription assay. Despite recent indications that promoter activity is simply a function of the 3'-terminal sequence of vir...

journal_title：Journal of virology

authors： Fodor E,Pritlove DC,Brownlee GG

更新日期：1994-06-01 00:00:00

abstract：:A high prevalence (42.6%) of hepatitis B virus (HBV) infection was suspected in 195 formerly captive orangutans due to a large number of serum samples which cross-reacted with human HBV antigens. It was assumed that such viral infections were contracted from humans during captivity. However, two wild orangutans were i...

journal_title：Journal of virology

authors： Warren KS,Heeney JL,Swan RA,Heriyanto,Verschoor EJ

更新日期：1999-09-01 00:00:00

abstract：:The ubiquitous human polyomavirus JC (JCV) is a small double-stranded DNA virus that establishes a persistent infection, and it is often transmitted from parents to children. There are at least 14 subtypes of the virus associated with different human populations. Because of its presumed codivergence with humans, JCV h...

journal_title：Journal of virology

authors： Shackelton LA,Rambaut A,Pybus OG,Holmes EC

更新日期：2006-10-01 00:00:00

abstract：:The lytic switch transactivator Zta initiates the ordered cascade of Epstein-Barr virus gene expression that culminates in virus production. Zta is a sequence-specific DNA-binding protein that transactivates early viral promotes via cis-acting sequences. Activation of some of these genes is mediated through binding to...

journal_title：Journal of virology

authors： Cayrol C,Flemington EK

更新日期：1995-07-01 00:00:00

abstract：:Autographa californica nuclear polyhedrosis virus (AcMNPV) is a double-stranded DNA virus that expresses several immediate-early genes under the control of different promoters. The expression of one of these transcription units, IE-N, is shown here, by a transient expression assay, to be regulated by both cis- and tra...

journal_title：Journal of virology

authors： Carson DD,Summers MD,Guarino LA

更新日期：1991-02-01 00:00:00

abstract：:In July 1991, an influenza A virus, designated A/Maryland/12/91 (A/MD), was isolated from the bronchial secretions of a 27-year-old animal caretaker. He had been admitted to the hospital with bilateral pneumonia and died of acute respiratory distress syndrome 13 days later. Antigenic analyses with postinfection ferret...

journal_title：Journal of virology

authors： Wentworth DE,Thompson BL,Xu X,Regnery HL,Cooley AJ,McGregor MW,Cox NJ,Hinshaw VS

更新日期：1994-04-01 00:00:00

abstract：:The human T-cell leukemia virus type 1 (HTLV-1) transmembrane glycoprotein has a 24-amino-acid cytoplasmic domain whose function in the viral life cycle is poorly understood. We introduced premature-stop mutations and 18 single-amino-acid substitutions into this domain and studied their effects on cell-to-cell transmi...

journal_title：Journal of virology

authors： Delamarre L,Pique C,Rosenberg AR,Blot V,Grange MP,Le Blanc I,Dokhélar MC

更新日期：1999-11-01 00:00:00