Effects of paraquat treatment on fish transaminase molecular subforms.

Abstract:

:The effects of paraquat (PQ; 1,1'-dimethyl-4,4'-bipyridylium dichloride) treatment were investigated in carp, silver carp and wels. The serum glutamic-oxalacetic transaminase (GOT; L-aspartate: 2-oxoglutarate aminotransferase, EC 2.6.1.1.) level was enhanced by 50% at 1 ppm exposure and by 100% at 10 ppm exposure in all species, and there was a change in the distribution of the molecular subforms of GOT in the liver and heart. The activities of the individual subforms decreased with increasing PQ concentration or after a longer exposure. In some cases, one of the subforms was no longer present in the liver. An increased serum GOT activity, a decreased enzyme activity in different organs and the disappearance of molecular subform indicate tissue damage.

journal_name

Fish Physiol Biochem

authors

Deér KA,Nemcsók J,Boross L,Szajáni B

doi

10.1007/BF00004434

subject

Has Abstract

pub_date

1990-01-01 00:00:00

pages

79-83

issue

1

eissn

0920-1742

issn

1573-5168

journal_volume

8

pub_type

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