[Major histocompatibility system as a risk factor for alcoholic liver disease].

Abstract:

:Several associations between alleles of the major histocompatibility system and alcoholic liver disease have been described. However, these are weak and change from one population to another. The aim of this work was to search for a possible genetic risk factor for alcoholic liver disease among Chilean alcoholics. We studied blood groups, serum proteins and HLA antigens in 39 alcoholic cirrhotics, 104 asymptomatic alcoholics and 44 non alcoholic controls. Asymptomatic alcoholics were also subjected to a percutaneous liver biopsy that showed moderate to severe histological liver damage in 46 subjects (44%). No differences in the studied genetic markers, were found among the four groups. It is concluded that this study does not confirm previously reported associations between genetic markers and alcoholic liver disease.

journal_name

Rev Med Chil

journal_title

Revista medica de Chile

authors

Llop E,Hirsch S,de la Maza MP,Bunout D,Iturriaga H,Silva C,Ugarte G,Rothhammer F

subject

Has Abstract

pub_date

1995-06-01 00:00:00

pages

687-93

issue

6

eissn

0034-9887

issn

0717-6163

journal_volume

123

pub_type

杂志文章
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    abstract::The author reminds the reform of medical education of 1945 in which he participated as a student. It was approved by the Decree #201 of april 2, introducing Chilean medicine into a new era of modernity. The reform was planned and conducted by professors Hernán Alessandri (1900-1980) and Alejandro Garretón (1900-1980) ...

    journal_title:Revista medica de Chile

    pub_type: 历史文章,杂志文章

    doi:

    authors: Cruz-Coke R

    更新日期:1995-08-01 00:00:00

  • [Application of marketing strategies for the management of public hospitals from the viewpoint of the staff members].

    abstract:BACKGROUND:The implementation of the marketing strategies in public hospitals provides management advantages and improves the relationship between customers and staff. AIM:To analyze the application of marketing strategies in a public hospital, from the perspective of the staff. MATERIAL AND METHODS:A structured surv...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:10.4067/s0034-98872006000300014

    authors: Riveros S J,Berné M C

    更新日期:2006-03-01 00:00:00

  • [Renal oncocytoma: 4 cases].

    abstract::Oncocytomas are tumors characterized by cells with an eosinophilic cytoplasm. Renal oncocytomas were described in 1942. Among 46 consecutive patients operated on for renal tumors, oncocytomas were found in 4 (8.7%). In spite of a supposedly benign nature, renal oncocytoma cannot be adequately differentiated from renal...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Castillo O,van Cauwelaert R,Aguirre C,Arellano L,Medina FJ

    更新日期:1992-05-01 00:00:00

  • [Prognostic factors for gastric cancer without lymph node involvement].

    abstract:BACKGROUND:The absence of lymph node involvement (N0) in gastric cancer is associated with a better survival. However some N0 gastric tumors still have a bad prognosis. AIM:To study demographic and morphological variables associated with prognosis in N0 gastric carcinoma. MATERIAL AND METHODS:Review of pathological r...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:/S0034-98872011000400003

    authors: Tapia O,Villaseca M,Bellolio E,Araya JC,Roa JC

    更新日期:2011-04-01 00:00:00

  • [Chronic hepatitis and cirrhosis caused by C virus before and after liver transplantation. Report of one case].

    abstract::We report a girl with a chronic hepatitis caused by C virus diagnosed at the age of nine, unsuccessfully treated with interferon and ribavirine. Two years later, she was subjected to a liver transplantation. She maintained elevated viral loads with a normal pathological study of the liver until 22 months after transpl...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:10.4067/s0034-98872004000400010

    authors: Alegría S,Buckel E,Ferrario M,Ceresa S,Smok G,Brahm J

    更新日期:2004-04-01 00:00:00

  • [Anticoagulant efficacy of different pharmacological presentations of vitamin K antagonists].

    abstract:BACKGROUND:Vitamin K antagonist medications (VKA) are essential for the prevention of thromboembolic events, but their effectiveness is influenced by multiple factors, such as the type of medication chosen. AIM:To evaluate the efficacy in anticoagulant control of the bioequivalent and non-bioequivalent drugs of acenoc...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:10.4067/S0034-98872020000901254

    authors: Rodríguez D,Nieto E,Quiroga T,Rojas E,Vera F

    更新日期:2020-09-01 00:00:00

  • [Association between food addiction and nutritional status in Chilean college students].

    abstract:BACKGROUND:High calorie foods, especially high in sugar and sodium may have an addictive potential. Experimental rats are able to develop symptoms and neurochemical changes, comparable to those observed in drug abuse, when they are exposed intermittently to sucrose. AIM:To evaluate the association between nutritional ...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:10.4067/S0034-98872015000500006

    authors: Obregón A,Fuentes J,Pettinelli P

    更新日期:2015-05-01 00:00:00

  • [Renal artery thrombosis after withdrawal from anticoagulation therapy in a kidney transplant recipient with thrombophilia: report of one case].

    abstract::Kidney graft loss because arterial thrombosis is not common and is related to risk factors such as recurrent vascular hemodialysis access thrombosis, collagen-vascular disease, repeated miscarriage, diabetes mellitus and thrombophilia. Patients having this last disorder have an increased risk of repeated thrombosis in...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:10.4067/s0034-98872007000100014

    authors: Vega S J,Goecke S H,Vásquez G A,Peña M A

    更新日期:2007-01-01 00:00:00

  • [Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis: advances in pathogenesis and treatment].

    abstract::ANCA (anti-neutrophil cytoplasmic antibodies) associated vasculitis or AAV are a group of diseases with predominant inflammation of small vessels and the presence of detectable ANCA in serum. Due to these common features, it is considered that AAV share pathogenic mechanisms. Consequently, a similar therapeutic approa...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章,评审

    doi:10.4067/S0034-98872013000600011

    authors: Silva F,Cisternas M

    更新日期:2013-06-01 00:00:00

  • [Mirizzi syndrome: experience of 77 cases].

    abstract::Mirizzi syndrome is estimated to occur in about 1% of cases requiring urgent or elective biliary tract surgery. The key anatomic finding is extrinsic compression of the common duct by a stone located in the gallbladder or cystic duct. Among patients operated on in the last 12 years we have found 77 patients meeting cr...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Jiménez O,Palacios JM,Correa R,Rojas M,Lopez O

    更新日期:1989-05-01 00:00:00

  • [Epidemiological profile of liver cirrhosis in Chile 1970-1992].

    abstract:BACKGROUND:Liver cirrhosis is an important public health problem in Chile. AIM:To review the main epidemiological features of liver cirrhosis in Chile in the last 22 years. METHODS:Review of yearbooks of mortality and causes of death of the Ministry of Health and Instituto Nacional de Estadísticas, review of hospital...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Serra I,Araneda J,Decinti E

    更新日期:1995-11-01 00:00:00

  • [Spontaneous hemoperitoneum caused by intraabdominal variceal rupture in a patient with liver cirrhosis. Clinical case].

    abstract::Spontaneous hemoperitoneum secondary to intraabdominal variceal rupture, is an uncommon and highly lethal complication of cirrhosis. We report a case of a 68 years old male submitted because of abdominal pain and fainting. The clinical and laboratory work up concluded that the patient had cirrhosis and hemoperitoneum....

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Moreno JP,Piña R,Rodríguez F,Korn O

    更新日期:2002-04-01 00:00:00

  • [Epidemiological transition: the other side of the coin].

    abstract::The model of epidemiological transition proposed by Omram explains the changes in disease patterns in communities. In societies with a high level of development this model has been complemented with the study of the post transition process. In this context, the emergence of allergic diseases, asthma and subsequently, ...

    journal_title:Revista medica de Chile

    pub_type: 社论

    doi:10.4067/s0034-98872006000600001

    authors: Valdivia G

    更新日期:2006-06-01 00:00:00

  • [Serotypes and antimicrobial susceptibility of Streptococcus agalactiae].

    abstract:BACKGROUND:Streptococcus agalactiae or group B streptococcus, GBS, is the leading cause of neonatal and maternal infections and an opportunistic pathogen in adults with underlying disease. In the last decade, a dramatic increase in the resistance of this microorganism to erythromycin and clindamycin has been observed. ...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:10.4067/s0034-98872004000500003

    authors: Martínez MA,Ovalle A,Durán C,Reid I,Urriola G,Garay B,Cifuentes M

    更新日期:2004-05-01 00:00:00

  • [Idiopathic recurrent ventricular tachycardia: role of verapamil in its treatment].

    abstract::Verapamil is a calcium channel blocker ideally suited for the treatment of A-V nodal reciprocating supraventricular tachycardia. Most types of ventricular tachycardia are refractory to treatment with verapamil since they depend on sodium channels. However, a few cases of recurrent ventricular tachycardia are refractor...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: González R,Fajuri A,Arriagada C,Marchesse M,Serrat H

    更新日期:1989-04-01 00:00:00

  • [Osteopoikilosis. A clinical case].

    abstract::We report a 35 years old female presenting with a right wrist pain. Physical examination was normal but, on a hand X ray examination, multiple dense para-articular bone foci were observed. Studying the rest of the skeleton, similar alterations were found in pelvis, knees, ankles, feet, shoulders and elbows. Osteopoiki...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Guerra M,Gutiérrez L,Vergara V,East F

    更新日期:1995-07-01 00:00:00

  • [The medical history of Edgar Allan Poe].

    abstract::Edgar Allan Poe, one of the best American storytellers and poets, suffered an episodic behaviour disorder partially triggered by alcohol and opiate use. Much confusion still exists about the last days of his turbulent life and the cause of his death at an early age. Different etiologies have been proposed to explain h...

    journal_title:Revista medica de Chile

    pub_type: 传,历史文章,杂志文章

    doi:10.4067/s0034-98872007000900019

    authors: Miranda C M

    更新日期:2007-09-01 00:00:00

  • [Dimensions of medical professionalism. Perspectives for the 21st. Century].

    abstract::Medicine is progressively loosing its prestige and efficacy and needs to rebuild the moral values that maintain the tacit social contract subscribed between doctors and patients. This altruistic commitment to serve people has been devaluated by changes in health systems, by advances in knowledge and by social and econ...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:10.4067/s0034-98872006000500016

    authors: Rosselot J E

    更新日期:2006-05-01 00:00:00

  • [Clinical and molecular features of cardial gastric cancer associated to Epstein Barr virus].

    abstract:BACKGROUND:Mortality caused by cardial gastric cancer in Chile, is increasing. Previously we demonstrated an association between Epstein Barr virus and this specific location of gastric cancer. AIM:To perform a clinical and molecular characterization of cardial gastric cancer associated to Epstein Barr virus. MATERIA...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:10.4067/s0034-98872005000700001

    authors: Corvalán A,Akiba S,Valenzuela MT,Cumsille MA,Koriyama C,Argandoña J,Backhouse C,Bal M,Mena F,Palma M,Eizuru Y

    更新日期:2005-07-01 00:00:00

  • [Immunogenicity and reactogenicity of a reduced antigen content diphtheria, tetanus and acellular pertussis vaccine dTpa) in 10 to 11 years old children and in adults].

    abstract:BACKGROUND:New vaccination strategies are needed to control the increasing problem of pertussis in teenagers and adults. AIM:To determine the immunogenicity and reactogenicity of a diphtheria-tetanus-acellular pertussis (dTpa) vaccine with reduced antigen content. MATERIAL AND METHODS:A single dose of the dTpa vaccin...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Abarca K,Valdivieso F,Potin M,Ibáñez I,Vial P

    更新日期:2002-05-01 00:00:00

  • [Seasonal patterns of infectious disease: similarity and differences].

    abstract:BACKGROUND:Most infectious diseases in template climates have seasonal pattern, that can be influenced by climatic, social and host factors. AIM:To study the seasonal patterns of seven human infectious diseases in Chile. MATERIAL AND METHODS:Series of monthly cases of measles, whooping cough, scarlet fever, meningiti...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Canals M

    更新日期:1997-04-01 00:00:00

  • [Antimicrobial activity of actinomycetes isolated from aquatic environments in southern Chile].

    abstract:BACKGROUND:The easy access and inappropriate use of antimicrobials led to selection and spread of resistant microorganisms strains. It is imperative to search for new and more effective antimicrobials. One strategy is the screening of metabolites produced by microorganisms found in the environment. Actinomycetes are a ...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:10.4067/s0034-98872004000200003

    authors: Leiva S,Yáñez M,Zaror L,Rodríguez H,García-Quintana H

    更新日期:2004-02-01 00:00:00

  • [Prevalence of risk factors to cardiovascular disease in group of Chilean employees].

    abstract:BACKGROUND:Cardiovascular diseases are the main causes of death in Chile and there is a high prevalence of cardiovascular risk factors in the population. AIM:To assess the prevalence of those risk factors in a group of employees. SUBJECTS AND METHODS:We studied 2,219 individuals, 1,378 males with a mean age of 46.2 +...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Lanas F,Del Solar J,Maldonado M,Guerrero MA,Espinoza F

    更新日期:2003-02-01 00:00:00

  • [Knowledge among physicians of the main cause of death in women].

    abstract:BACKGROUND:There is a misconception that the main cause of death among women is breast cancer, even among physicians, who may neglect cardiovascular preventive measures in this gender Aim: To assess the knowledge among physicians about the main cause of death among women. MATERIAL AND METHODS:A survey was answered by ...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:10.4067/S0034-98872018001001167

    authors: Fernández M,Parra M,Calligaris S,Parada V,Ojeda MJ,Quiroz S,Carreño C

    更新日期:2018-12-01 00:00:00

  • [Multiple splenic abscesses. Report of 2 cases].

    abstract::Splenic abscesses are infrequent and usually associated to sepsis and immunodepression. The diagnosis is commonly made in the necropsy. We report two cases of multiple splenic abscesses in type II diabetic patients that were diagnosed by ultrasound. Both patients were successfully managed with surgery (drainage of lef...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Gatica MA,Morales H,Harz C,Espinoza A

    更新日期:1993-05-01 00:00:00

  • [Melkersson-Rosenthal syndrome: report of 3 cases].

    abstract::Melkersson-Rosenthal syndrome is characterized by facial or lip edema, peripheral facial palsy and scrotal tongue. We report three patients with the syndrome. A 17 years old male had malar and superior lip enlargement that coincided with a peripheral facial palsy. A 40 years old male with recurrent facial palsy presen...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Donoso A,Esguep A

    更新日期:1995-12-01 00:00:00

  • [Use of platelet rich plasma in knee ligament surgery].

    abstract::Platelet Rich Plasma (PRP) is used in musculoskeletal lesion surgery, including muscle, bone, tendons and ligaments. PRP might accelerate the healing process and the integration of the graft, allowing an earlier return to sports activities of patients. PRP is obtained from autologous blood, which is centrifuged, obtai...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章,评审

    doi:10.4067/S0034-98872013001000011

    authors: Figueroa P D,Figueroa B F,Ahumada P X,Calvo R R,Vaisman B A

    更新日期:2013-10-01 00:00:00

  • [Aortic valve multiple papillary fibroelastoma complicated with a cerebrovascular accident: Report of one case].

    abstract::The echocardiographic identification of cardiac tumors as cause of embolic episodes is infrequent, and the finding of multiple papillary fibroelastoma is even less common. We report a 70 years old female with a history of a rheumatic mitral valve lesion, subjected to a commissurotomy in 1970. She was admitted with a c...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Córdova S,Zalaquett R,Chuaqui B,Casanegra P,Chamorro G

    更新日期:2001-09-01 00:00:00

  • [Epithelial lesions associated with gallbladder carcinoma. A methodical study of 32 cases].

    abstract::Using mapping techniques, 32 consecutive gallbladder carcinomas diagnosed in our department were studied. The defined lesions were dysplasia, carcinoma in situ and superficial spreading carcinoma. A total of 2257 lesions were recorded from 1072 inclusions. All the defined lesions were present in about 10% of all secti...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:

    authors: Roa I,Araya JC,Wistuba I,Villaseca M,de Aretxabala X,Busel D,Burgos L

    更新日期:1993-01-01 00:00:00

  • [Small intestine bacterial overgrowth in patients with chronic pancreatitis].

    abstract:BACKGROUND:Previous reports describe 30-40% of small intestine bacterial overgrowth (SIBO) in patients with chronic pancreatitis (CP), SIBO is a cause of persistent symptoms in this group of patients even when they are treated with pancreatic enzymes. AIM:To asses the frequency of SIBO in patients with CP. PATIENTS A...

    journal_title:Revista medica de Chile

    pub_type: 杂志文章

    doi:/S0034-98872008000800003

    authors: Mancilla A C,Madrid S AM,Hurtado H C,Orellana B C,Peña Z M,Tobar A E,Berger F Z

    更新日期:2008-08-01 00:00:00