Abstract：
:Gout disease in our country as both exogenous factors (dietary habits, professions, etc.) and endogenous factors (sex, inheritance, etc.) play a polygenic role in its incidence. Those conditions resulting in hyperuricemia (diseases, drugs, etc.) facilitate the clinical manifestations. But a genetic determinant in the articular reaction in front of an accumulation of uric acid crystals or in the development of such crystallization is a fundamental factor in the manifestation of the disease. In our series we were able to confirm the high incidence of arterial hypertension, renal lithiasis and renal participation in gout. The role of lead and of certain professions in favouring the hyperuricemia is suggested. A classification of gout, from a functional point of view, must include both the clinical form and the analysis of the whole renal function, and the renal handling of uric acid. This is mandatory not only for the diagnosis and prognosis of the disease but to set the basis of its adequate management.
journal_name
Adv Exp Med Bioljournal_title
Advances in experimental medicine and biologyauthors
Rapado A,Castrillo JMdoi
10.1007/978-1-4684-3285-5_32subject
Has Abstractpub_date
1977-01-01 00:00:00pages
223-30eissn
0065-2598issn
2214-8019journal_volume
76Bpub_type
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journal_title：Advances in experimental medicine and biology
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更新日期：1989-01-01 00:00:00
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更新日期：1998-01-01 00:00:00
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