Medial amygdala enhances synaptic transmission and synaptic plasticity in the dentate gyrus of rats in vivo.

abstract：:We have demonstrated that 4-aminopyridine-3-methanol (4-AP-3-MeOH), a 4-aminopyridine derivative, significantly restores axonal conduction in stretched spinal cord white-matter strips and shows no preference in restoring large and small axons. This compound is 10 times more potent when compared with 4-AP and other der...

journal_title：Journal of neurophysiology

authors： Sun W,Smith D,Fu Y,Cheng JX,Bryn S,Borgens R,Shi R

更新日期：2010-01-01 00:00:00

abstract：:1. In decerebrate paralyzed cats, we observed the responses of ventral and dorsal medullary inspiratory (I) neurons to two types of vagal afferent input that shorten neural I: lung inflation and vagal electrical stimulation. 2. A study population of 15 I neurons whose firing patterns suggested involvement in the inspi...

journal_title：Journal of neurophysiology

authors： Cohen MI,Huang WX,Barnhardt R,See WR

更新日期：1993-05-01 00:00:00

abstract：:A series of studies were carried out to investigate the role of the cerebellar flocculus and ventral paraflocculus in the ability to voluntarily cancel the vestibuloocular reflex (VOR). Squirrel monkeys were trained to pursue moving visual targets and to fixate a head stationary or earth stationary target during passi...

journal_title：Journal of neurophysiology

authors： Belton T,McCrea RA

更新日期：2000-09-01 00:00:00

abstract：:Previous studies have rarely tested whether the activity of high-frequency discharge (HFD) neurons of the basal ganglia (BG) is modulated by expectation, delivery, and omission of aversive events. Therefore the full value domain encoded by the BG network is still unknown. We studied the activity of HFD neurons of the ...

journal_title：Journal of neurophysiology

authors： Joshua M,Adler A,Rosin B,Vaadia E,Bergman H

更新日期：2009-02-01 00:00:00

abstract：:It is not known how changes in skin mechanics affect the responses of cutaneous mechanoreceptors in the finger pads to compression forces. We used venous occlusion to change the stiffness of the fingers and investigated whether this influenced the firing of low-threshold mechanoreceptors to surfaces of differing stiff...

journal_title：Journal of neurophysiology

authors： Hudson KM,Condon M,Ackerley R,McGlone F,Olausson H,Macefield VG,Birznieks I

更新日期：2015-10-01 00:00:00

abstract：:We studied the properties of voltage-activated outward currents in two types of spider cuticular mechanoreceptor neurons to learn if these currents contribute to the differences in their adaptation properties. Both types of neurons adapt rapidly to sustained stimuli, but type A neurons usually only fire one or two act...

journal_title：Journal of neurophysiology

authors： Sekizawa SI,French AS,Höger U,Torkkeli PH

更新日期：1999-06-01 00:00:00

abstract：:Synaptic currents are frequently assumed to make a major contribution to the extracellular field potential (EFP). However, in any neuronal population, the explicit separation of synaptic sources from other contributions such as postsynaptic spikes remains a challenge. Here we take advantage of the simple organization ...

journal_title：Journal of neurophysiology

authors： McColgan T,Kuokkanen PT,Carr CE,Kempter R

更新日期：2019-03-01 00:00:00

abstract：:Respiratory depression is a therapy-limiting side effect of opioid analgesics, yet our understanding of the brain circuits mediating this potentially lethal outcome remains incomplete. Here we studied the contribution of the rostral ventromedial medulla (RVM), a region long implicated in pain modulation and homeostati...

journal_title：Journal of neurophysiology

authors： Phillips RS,Cleary DR,Nalwalk JW,Arttamangkul S,Hough LB,Heinricher MM

更新日期：2012-11-01 00:00:00

abstract：:This study investigated the influence of different modalities of target information (visual, kinesthetic) on the accuracy, kinematics, and interjoint coordination of pointing movements to remembered targets. The targets were presented by a robot arm in five locations in three-dimensional (3D) space, either as a point ...

journal_title：Journal of neurophysiology

authors： Adamovich SV,Berkinblit MB,Fookson O,Poizner H

更新日期：1998-06-01 00:00:00

abstract：:Recent studies have shown that sympathetic nervous system (SNS) activity can be heavily impacted not only by basic threats to survival but also by threats to social bonds. In this study we explored the behavioral and physiological consequences of social exclusion/inclusion in patients with psoriasis, a disease frequen...

journal_title：Journal of neurophysiology

authors： Ponsi G,Monachesi B,Panasiti V,Aglioti SM,Panasiti MS

更新日期：2019-01-01 00:00:00

abstract：:Silencing-induced homeostatic plasticity is usually expressed as a change in the amplitude or the frequency of miniature postsynaptic currents. Here we report that, prolonged (approximately 24 h) silencing of mature (20-22 days in vitro) cultured hippocampal neurons using the voltage-gated sodium channel blocker tetro...

journal_title：Journal of neurophysiology

authors： Sokolova IV,Mody I

更新日期：2008-08-01 00:00:00

abstract：:1. Physiological responses of hippocampal pyramidal neurons in primary culture to prolonged glutamate (GLU) exposure (500 microM in all experiments) were studied with the use of patch electrodes and whole-cell current-clamp recording techniques. In some experiments, perforated patch recordings were employed with elect...

journal_title：Journal of neurophysiology

authors： Coulter DA,Sombati S,DeLorenzo RJ

更新日期：1992-08-01 00:00:00

abstract：:A number of studies have indicated an important role for N-methyl-D-aspartate (NMDA) receptors in cell survival versus cell death decisions during neuronal development, trauma, and ischemia. Coupling of neurons by electrical synapses (gap junctions) is high or increases in neuronal networks during all three of these c...

journal_title：Journal of neurophysiology

authors： de Rivero Vaccari JC,Corriveau RA,Belousov AB

更新日期：2007-11-01 00:00:00

abstract：:1. It is widely believed that signals contributing to the receptive field surrounds of retinal bipolar cells pass from horizontal cells to bipolar cells via GABAergic synapses. To test this notion, we applied gamma-aminobutyric acid (GABA) agonists and antagonists to isolated, perfused retinas of the salamander Ambyst...

journal_title：Journal of neurophysiology

authors： Hare WA,Owen WG

更新日期：1996-09-01 00:00:00

abstract：:To investigate the dependence of velocity characteristics on spatiotemporal interactions the velocity selectivity of 15 geniculate and 72 cortical cells (areas 17 and 18) was examined with light and dark bars before and after masking all but the most sensitive part of the receptive field. The use of a 0.3 degree windo...

journal_title：Journal of neurophysiology

authors： Duysens J,Orban GA,Cremieux J

更新日期：1985-10-01 00:00:00

abstract：:We have investigated the fundamental properties of central auditory glycinergic synapses in early postnatal development in normal and congenitally deaf (dn/dn) mice. Glycinergic miniature inhibitory postsynaptic currents (mIPSCs) were recorded using patch-clamp methods in neurons from a brain slice preparation of the ...

journal_title：Journal of neurophysiology

authors： Leao RN,Oleskevich S,Sun H,Bautista M,Fyffe RE,Walmsley B

更新日期：2004-02-01 00:00:00

abstract：:Dorsal root afferent depolarization and antidromic firing were studied in isolated spinal cords of neonatal rats. Spontaneous firing accompanied by occasional bursts could be recorded from most dorsal roots in the majority of the cords. The afferent bursts were enhanced after elevation of the extracellular potassium c...

journal_title：Journal of neurophysiology

authors： Kremer E,Lev-Tov A

更新日期：1998-05-01 00:00:00

abstract：:1. The vestibuloocular reflex (VOR) undergoes long-term adaptive changes in the presence of persistent retinal image motion during head turns. Previous experiments using natural stimuli have provided evidence that the VOR is subserved by parallel pathways, including some that are modified during learning and some that...

journal_title：Journal of neurophysiology

authors： Broussard DM,Brontë-Stewart HM,Lisberger SG

更新日期：1992-06-01 00:00:00

abstract：:Pharmacological modulation of gamma-aminobutyric acid-A (GABAA) receptors can provide important information on the types of subunits composing these receptors. In recombinant studies, zinc more potently inhibits alphabeta subunits compared with the alphabetagamma combination, whereas modulation by nanomolar concentrat...

journal_title：Journal of neurophysiology

authors： Defazio T,Hablitz JJ

更新日期：1998-10-01 00:00:00

abstract：:Animals and human beings sense and react to real/potential dangerous stimuli. However, the supraspinal mechanisms relating noxious sensing and nocifensive behavior are mostly unknown. The collateralization and spatial organization of interrelated neurons are important determinants of coordinated network function. Here...

journal_title：Journal of neurophysiology

authors： Leiras R,Martín-Cora F,Velo P,Liste T,Canedo A

更新日期：2016-01-01 00:00:00

abstract：:Visual search is a ubiquitous visual behavior, and efficient search is essential for survival. Different cognitive models have explained the speed and accuracy of search based either on the dynamics of attention or on similarity of item representations. Here, we examined the extent to which performance on a visual sea...

journal_title：Journal of neurophysiology

authors： Cohen MA,Alvarez GA,Nakayama K,Konkle T

更新日期：2017-01-01 00:00:00

abstract：:The primary motor cortex (MI) commands motor output after kinematics are planned from goals, thought to occur in a larger premotor network. However, there is a growing body of evidence that MI is involved in processes beyond action generation, and neuronal subpopulations may perform computations related to cue-to-acti...

journal_title：Journal of neurophysiology

authors： Rao NG,Donoghue JP

更新日期：2014-01-01 00:00:00

abstract：:Extracellular recordings of 209 neurons were obtained with carbon fiber-containing multibarrel micropipettes. The cells were isolated in the primary somatosensory cortex of cats anesthetized with barbiturate and classified according to the nature of their response to natural stimuli, the nature of the surrounding mult...

journal_title：Journal of neurophysiology

authors： Dykes RW,Landry P,Metherate R,Hicks TP

更新日期：1984-12-01 00:00:00

abstract：:The centre médian-parafascicular (CM-Pf) complex is located at the posterior intralaminar nuclei of the thalamus and forms part of the nonspecific thalamocortical projection system and the internal circuit of the basal ganglia. However, the functional roles of this complex remain to be fully elucidated. Here we have e...

journal_title：Journal of neurophysiology

authors： Minamimoto T,Kimura M

更新日期：2002-06-01 00:00:00

abstract：:A fundamental question in systems biology addresses the issue of how flexibility is built into modulatory networks such that they can produce context-dependent responses. Here we examine flexibility in the serotonin (5-HT) response system that modulates the cycle frequency (cf) of a rhythmic motor output. We found tha...

journal_title：Journal of neurophysiology

authors： Spitzer N,Cymbalyuk G,Zhang H,Edwards DH,Baro DJ

更新日期：2008-06-01 00:00:00

abstract：:We have previously shown that control subjects use two distinct temporal strategies when stepping on an inclined surface during walking: one for level and 10 degrees surfaces and another for 20 and 30 degrees surfaces. These two temporal strategies were characterized by systematic shifts in the timing of muscle activi...

journal_title：Journal of neurophysiology

authors： Earhart GM,Bastian AJ

更新日期：2001-02-01 00:00:00

abstract：:The possibility of using randomly generated stimulus intervals (with a Poisson distribution) to identify the type(s) of intrafusal fiber activated by the stimulation of single static gamma axons was tested in Peroneus tertius muscle spindles of anesthetized cats. Three patterns of random stimulation with different val...

journal_title：Journal of neurophysiology

authors： Petit J,Banks RW,Laporte Y

更新日期：1999-06-01 00:00:00

abstract：:Traumatic brain injury (TBI) is one of the most common neurological disorders causing memory reduction, particularly short-term memory (STM). We showed that, during TBI-induced inflammation, increased blood content of fibrinogen (Fg) enhanced vascular protein transcytosis and deposition of extravasated Fg in vasculo-a...

journal_title：Journal of neurophysiology

authors： Charkviani M,Muradashvili N,Sulimai N,Lominadze D

更新日期：2020-08-01 00:00:00

abstract：:We investigated the role of the superior colliculus (SC) in saccade target selection in rhesus monkeys who were trained to perform a direction-discrimination task. In this task, the monkey discriminated between opposed directions of visual motion and indicated its judgment by making a saccadic eye movement to one of t...

journal_title：Journal of neurophysiology

authors： Horwitz GD,Newsome WT

更新日期：2001-11-01 00:00:00

abstract：:Memory for past events may be based on retrieval accompanied by specific contextual details (recollection) or on the feeling that an item is old (familiarity) or new (novelty) in the absence of contextual details. There are indications that recollection, familiarity, and novelty involve different medial temporal lobe ...

journal_title：Journal of neurophysiology

authors： Daselaar SM,Fleck MS,Cabeza R

更新日期：2006-10-01 00:00:00