DNA detection and seroprevalence of human papillomavirus in a cohort of adolescent women.

Abstract:

OBJECTIVES:Human papillomavirus (HPV) infections are common in adolescent women, while the rare cancerous sequelae of HPV infections do not generally occur until the 4th or 5th decades of life. This prospective study of a cohort of adolescent women was performed to further our knowledge of the natural history of incident and prevalent HPV infections. METHODS:Self-vaginal swabs collected from high-risk, unvaccinated adolescent women in a longitudinal study were analysed for HPV DNA. Sera were collected at enrolment and later tested for HPV antibodies. Statistical analysis was performed to determine the HPV genotype distribution and duration of detection, and to determine rates of seropositivity and seroconversion for HPV types represented in the assays. RESULTS:146 subjects (mean enrolment age=15.4 years; mean duration of follow-up=5.8 years) had samples adequate for analysis of HPV detection, and 95 of these subjects had paired sera available. The cumulative prevalence for high-risk and low-risk HPV types was 95.9% and 91.1%, respectively. HPV types 6, 11, 16 and 18 (HPV types represented in the quadrivalent vaccine) were found at some point in 40.4%, 6.2%, 48% and 24% of participants, respectively. Serological data confirmed exposure to these vaccine-covered types, as well as to other high-risk HPV types. CONCLUSIONS:In this cohort of adolescent women, high- and low-risk HPV types were frequently detected, and serological data confirmed exposure in most subjects. The high-prevalence HPV types represented in the quadrivalent HPV vaccine further support vaccination of women at an age well before sexual debut.

journal_name

Sex Transm Infect

authors

Ermel AC,Shew ML,Weaver BA,Qadadri B,Denski C,Tu W,Tong Y,Fortenberry JD,Brown DR

doi

10.1136/sextrans-2012-050886

subject

Has Abstract

pub_date

2014-02-01 00:00:00

pages

64-9

issue

1

eissn

1368-4973

issn

1472-3263

pii

sextrans-2012-050886

journal_volume

90

pub_type

杂志文章
  • Human papillomavirus (HPV) vaccination and oropharyngeal HPV in ethnically diverse, sexually active adolescents: community-based cross-sectional study.

    abstract:OBJECTIVES:Oropharyngeal squamous cell carcinoma is the most common human papillomavirus (HPV)-associated cancer in the UK, but little is known about the prevalence of oropharyngeal HPV in sexually active teenagers. We investigated reported HPV vaccination coverage (in females) and prevalence of oropharyngeal HPV in se...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章

    doi:10.1136/sextrans-2020-054428

    authors: Kerry-Barnard S,Beddows S,Reid F,Beckley-Hoelscher N,Soldan K,Panwar K,Seran C,Fleming C,Lesniewska A,Planche T,Williamson J,Hay P,Oakeshott P

    更新日期:2020-09-03 00:00:00

  • Screening for syphilis during pregnancy in Nigeria: a practice that must continue.

    abstract:OBJECTIVE:To determine the seroprevalence rate of syphilis among pregnant women attending the antenatal clinics of a teaching and a state specialist hospital in Nigeria, in order to ascertain whether maternal screening should be incorporated into routine antenatal care of our hospitals. METHODS:A screening for syphili...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章

    doi:10.1136/sti.2006.023416

    authors: Taiwo SS,Adesiji YO,Adekanle DA

    更新日期:2007-08-01 00:00:00

  • HSV-2 incidence by sex over four age periods to age 38 in a birth cohort.

    abstract:OBJECTIVES:To examine herpes simplex virus type 2 (HSV-2) incidence over four periods to age 38 in a birth cohort, and to compare risks for men and women, taking into account sexual behaviour. METHODS:At ages 21, 26, 32 and 38, participants in the Dunedin Multidisciplinary Health and Development Study were invited to ...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章

    doi:10.1136/sextrans-2013-051235

    authors: Dickson N,Righarts A,van Roode T,Paul C,Taylor J,Cunningham AL

    更新日期:2014-05-01 00:00:00

  • Surveillance of HIV in the army of the Republic of Cyprus (SHARC); rationale, design, and implementation of an inexpensive system.

    abstract:OBJECTIVES:To design and implement an HIV surveillance system using periodic cross sectional prevalence surveys in National Guard recruits of the Republic of Cyprus. METHODS:HIV infection surveillance used unlinked anonymous screening (UAS) methodology, which tested residual blood originally collected for other purpos...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章

    doi:10.1136/sti.78.1.50

    authors: Kyriakides T,Eleftheriou A,Michaelides N,Papantoniou L

    更新日期:2002-02-01 00:00:00

  • The incidence of Trichomonas vaginalis infection in women attending nine sexually transmitted diseases clinics in the USA.

    abstract:OBJECTIVES:Trichomoniasis (TV) is associated with an increased risk of acquisition of sexually transmitted diseases (STDs) and HIV. The purpose of this study is to evaluate factors associated with incidence TV among female STD clinic attendees in the USA. METHODS:Data were collected from women participating in a rando...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1136/sextrans-2015-052010

    authors: Alcaide ML,Feaster DJ,Duan R,Cohen S,Diaz C,Castro JG,Golden MR,Henn S,Colfax GN,Metsch LR

    更新日期:2016-02-01 00:00:00

  • Role of core and bridging groups in the transmission dynamics of HIV and STIs in Cotonou, Benin, West Africa.

    abstract::The potential for exposure of low and high risk women to HIV and sexually transmitted infections (STI) through unprotected sex with male clients of female sex workers in Cotonou could account for most if not all of the estimated yearly numbers of HIV infections in Cotonou women (approximately 1000). As ongoing transmi...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章

    doi:10.1136/sti.78.suppl_1.i69

    authors: Lowndes CM,Alary M,Meda H,Gnintoungbé CA,Mukenge-Tshibaka L,Adjovi C,Buvé A,Morison L,Laourou M,Kanhonou L,Anagonou S

    更新日期:2002-04-01 00:00:00

  • Prevalence and clinical characteristics of patients with biologically false-positive reactions with serological syphilis testing in contemporary practice: 10-year experience at a tertiary academic hospital.

    abstract:OBJECTIVES:Biologically false positive (BFP) reactions are well described in early literature. However, only a few recent reports described the incidence and clinical characteristics of patients with BFP reactions. We reviewed the serological test results of patients tested for syphilis in our hospital in the past deca...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章

    doi:10.1136/sextrans-2020-054628

    authors: Ishihara Y,Okamoto K,Shimosaka H,Ono Y,Kanno Y,Ikeda M,Harada S,Kurano M,Okugawa S,Moriya K,Yatomi Y

    更新日期:2020-11-18 00:00:00

  • Incidence of severe reproductive tract complications associated with diagnosed genital chlamydial infection: the Uppsala Women's Cohort Study.

    abstract:OBJECTIVE:To estimate the cumulative incidence of severe complications associated with genital chlamydia infection in the general female population. METHODS:The Uppsala Women's Cohort Study was a retrospective population based cohort study in Sweden, linking laboratory, hospital, and population registers. We estimated...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章

    doi:10.1136/sti.2005.017186

    authors: Low N,Egger M,Sterne JA,Harbord RM,Ibrahim F,Lindblom B,Herrmann B

    更新日期:2006-06-01 00:00:00

  • The feasibility of integrated STI prevalence and behaviour surveys in developing countries.

    abstract:BACKGROUND:In countries where STI/HIV prevalence data and behavioural data are scarce UNAIDS second generation HIV surveillance guidelines recommend measuring STI/HIV prevalence and risk behaviours in vulnerable populations but do not recommend conducting these surveys concurrently because of concerns about participati...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章

    doi:10.1136/sti.78.3.187

    authors: MacLachlan EW,Baganizi E,Bougoudogo F,Castle S,Mint-Youbba Z,Gorbach P,Parker K,Ryan CA

    更新日期:2002-06-01 00:00:00

  • Molecular test for chlamydia and gonorrhoea used at point of care in remote primary healthcare settings: a diagnostic test evaluation.

    abstract:OBJECTIVES:A new molecular test for Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) (GeneXpert CT/NG) has been demonstrated to be as accurate as conventional nucleic acid amplification tests (NAAT), but performance has not been evaluated in routine primary care, performed at the point of care by clinicians. W...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章,随机对照试验

    doi:10.1136/sextrans-2017-053443

    authors: Causer LM,Guy RJ,Tabrizi SN,Whiley DM,Speers DJ,Ward J,Tangey A,Badman SG,Hengel B,Natoli LJ,Anderson DA,Wand H,Wilson D,Regan DG,Shephard M,Donovan B,Fairley CK,Kaldor JM

    更新日期:2018-08-01 00:00:00

  • "A bit more truthful": the validity of adolescent sexual behaviour data collected in rural northern Tanzania using five methods.

    abstract:OBJECTIVE:To assess the validity of sexual behaviour data collected from African adolescents using five methods. METHODS:9280 Tanzanian adolescents participated in a biological marker and face to face questionnaire survey and 6079 in an assisted self-completion questionnaire survey; 74 participated in in-depth intervi...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章

    doi:10.1136/sti.2004.011924

    authors: Plummer ML,Ross DA,Wight D,Changalucha J,Mshana G,Wamoyi J,Todd J,Anemona A,Mosha FF,Obasi AI,Hayes RJ

    更新日期:2004-12-01 00:00:00

  • A novel condom policy for young attenders at a sexual health clinic.

    abstract:OBJECTIVES:To review the uptake of a new service for condom provision in the under 16s. METHODS:A retrospective case note review of attenders at an inner London sexual health clinic. RESULTS:The service was audited over a 3 month period in the spring of 2000. There were 97 individual attendances, 94% (92) male and 6%...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章

    doi:10.1136/sti.77.4.287

    authors: Wright S,Tobin R,Kell P,Franks J

    更新日期:2001-08-01 00:00:00

  • Use of gay app and the associated HIV/syphilis risk among non-commercial men who have sex with men in Shenzhen, China: a serial cross-sectional study.

    abstract:OBJECTIVES:Geosocial networking application specific to men who have sex with men (MSM) (gay app) has revolutionised the social networking of MSM globally, much concern was raised over its linkage to HIV/syphilis risk. This study sought to examine the association between use of gay app and sexual behaviours and HIV/syp...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章

    doi:10.1136/sextrans-2018-053902

    authors: Wei L,Chen L,Zhang H,Yang Z,Zou H,Yuan T,Xiao Y,Liu S,Tan W,Xie W,Liu L,Cheng J,Zhao J

    更新日期:2019-11-01 00:00:00

  • Seroadaptive behaviours among men who have sex with men in San Francisco: the situation in 2008.

    abstract:OBJECTIVES:To assess changes in seroadaptive behaviours among men who have sex with men (MSM) in San Francisco over the past 4 years. METHODS:461 MSM were recruited in 2008 as the second wave of the US National HIV Behavioural Surveillance (NHBS) survey in San Francisco. Participants were classified into patterns of s...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章

    doi:10.1136/sti.2010.042986

    authors: Snowden JM,Raymond HF,McFarland W

    更新日期:2011-03-01 00:00:00

  • A fruitful alliance: the synergy between Atopobium vaginae and Gardnerella vaginalis in bacterial vaginosis-associated biofilm.

    abstract:OBJECTIVES:Bacterial vaginosis (BV) is characterised by a change in the microbial composition of the vagina. The BV-associated organisms outnumber the health-associated Lactobacillus species and form a polymicrobial biofilm on the vaginal epithelium, possibly explaining the difficulties with antibiotic treatment. A bet...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章

    doi:10.1136/sextrans-2015-052475

    authors: Hardy L,Jespers V,Abdellati S,De Baetselier I,Mwambarangwe L,Musengamana V,van de Wijgert J,Vaneechoutte M,Crucitti T

    更新日期:2016-11-01 00:00:00

  • Condom effectiveness for prevention of Chlamydia trachomatis infection.

    abstract:BACKGROUND/OBJECTIVES:A growing body of evidence is increasingly demonstrating the effectiveness of condoms for sexually transmitted infection (STI) prevention. The purpose of the present analysis was to provide a disease specific estimate for the effectiveness of condoms in preventing Chlamydia trachomatis infection w...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章

    doi:10.1136/sti.2004.012799

    authors: Niccolai LM,Rowhani-Rahbar A,Jenkins H,Green S,Dunne DW

    更新日期:2005-08-01 00:00:00

  • Drifting towards ceftriaxone treatment failure in gonorrhoea: risk factor analysis of data from the Gonococcal Resistance to Antimicrobials Surveillance Programme in England and Wales.

    abstract:OBJECTIVES:Treatment of Neisseria gonorrhoeae is threatened by the emergence of antimicrobial resistance. We analysed data from the Gonococcal Resistance to Antimicrobials Surveillance Programme (GRASP) in England and Wales to identify groups most at risk of reduced susceptibility to the currently recommended first-lin...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章

    doi:10.1136/sextrans-2016-052583

    authors: Town K,Obi C,Quaye N,Chisholm S,Hughes G,GRASP Collaborative Group.

    更新日期:2017-02-01 00:00:00

  • Mycoplasma genitalium is not associated with adverse outcomes of pregnancy in Guinea-Bissau.

    abstract:OBJECTIVE:To evaluate the impact of Mycoplasma genitalium on the outcome of pregnancy. METHODS:Cervical samples from women who had previously participated in a case-control study (designed to assess the impact of syphilis and HIV-2 on the outcome of pregnancy in Guinea-Bissau) were processed using a PCR assay to detec...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章

    doi:10.1136/sti.78.4.289

    authors: Labbé AC,Frost E,Deslandes S,Mendonça AP,Alves AC,Pépin J

    更新日期:2002-08-01 00:00:00

  • Safety and acceptability of vaginal disinfection with benzalkonium chloride in HIV infected pregnant women in west Africa: ANRS 049b phase II randomized, double blinded placebo controlled trial. DITRAME Study Group.

    abstract:OBJECTIVES:To study the tolerance and acceptability in Africa of a perinatal intervention to prevent vertical HIV transmission using benzalkonium chloride disinfection. DESIGN:A randomized, double blinded phase II trial. SETTING:Prenatal care units in Abidjan (Côte d'Ivoire) and Bobo-Dioulasso (Burkina Faso). PATIEN...

    journal_title:Sexually transmitted infections

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1136/sti.75.6.420

    authors: Msellati P,Meda N,Leroy V,Likikouët R,Van de Perre P,Cartoux M,Bonard D,Ouangre A,Combe P,Gautier-Charpentier L,Sylla-Koko F,Lassalle R,Dosso M,Welffens-Ekra C,Dabis F,Mandelbrot L

    更新日期:1999-12-01 00:00:00

  • Criminal prosecution of a male partner for sexual transmission of infectious diseases: the views of educated people living in Togo.

    abstract:OBJECTIVE:To examine the views of educated people in Togo on the acceptability of criminal prosecution of a male partner for sexual transmission of infectious diseases (STIDs) to his female partner. METHODS:199 adults living in Kara, Togo judged acceptability of criminal prosecution for STID in 45 scenarios composed o...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章

    doi:10.1136/sextrans-2012-050964

    authors: Kpanake L,Patassi A,Mullet E

    更新日期:2013-06-01 00:00:00

  • Antibodies to Trichomonas vaginalis surface glycolipid.

    abstract:BACKGROUND:Human trichomoniasis is the most common non-viral sexually transmitted disease, yet immune responses are not well studied. METHODS:Since the Trichomonas vaginalis lipophosphoglycan (TvLPG) is an important virulence factor, a bank of eight monoclonal antibodies was generated to define the antigen in clinical...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章

    doi:10.1136/sextrans-2012-051013

    authors: Bastida-Corcuera FD,Singh BN,Gray GC,Stamper PD,Davuluri M,Schlangen K,Corbeil RR,Corbeil LB

    更新日期:2013-09-01 00:00:00

  • Syndromic management of sexually transmitted diseases at primary care level, Mozambique.

    abstract:OBJECTIVE:To assess STD management in primary healthcare facilities where STD clinics and syndromic management guidelines had been introduced. METHODS:In 26 health facilities in selected sites, we observed management of all STD patients presenting in the adult general or STD clinic. We assessed the referral system by ...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章

    doi:10.1136/sti.78.1.e2

    authors: Mbofana FS,Brito FJ,Saifodine A,Cliff JL

    更新日期:2002-02-01 00:00:00

  • A comparison of respondent-driven and venue-based sampling of female sex workers in Liuzhou, China.

    abstract:OBJECTIVES:To compare two methods for sampling female sex workers (FSWs) for bio-behavioural surveillance. We compared the populations of sex workers recruited by the venue-based Priorities for Local AIDS Control Efforts (PLACE) method and a concurrently implemented network-based sampling method, respondent-driven samp...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章

    doi:10.1136/sextrans-2012-050638

    authors: Weir SS,Merli MG,Li J,Gandhi AD,Neely WW,Edwards JK,Suchindran CM,Henderson GE,Chen XS

    更新日期:2012-12-01 00:00:00

  • Comprehensive testing for, and diagnosis of, sexually transmissible infections among Australian gay and bisexual men: findings from repeated, cross-sectional behavioural surveillance, 2003-2012.

    abstract:OBJECTIVES:To analyse changes in testing for sexually transmissible infections (STI) among gay and bisexual men in Melbourne, Sydney and Queensland, Australia, particularly comprehensive STI testing (at least four tests from different anatomical sites in the previous year), and the characteristics of men who had such t...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章,多中心研究

    doi:10.1136/sextrans-2013-051294

    authors: Holt M,Hull P,Lea T,Guy R,Bourne C,Prestage G,Zablotska I,de Wit J,Mao L

    更新日期:2014-05-01 00:00:00

  • Genetic diversity in Trichomonas vaginalis.

    abstract::Recent advances in genetic characterisation of Trichomonas vaginalis isolates show that the extensive clinical variability in trichomoniasis and its disease sequelae are matched by significant genetic diversity in the organism itself, suggesting a connection between the genetic identity of isolates and their clinical ...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章,评审

    doi:10.1136/sextrans-2013-051098

    authors: Meade JC,Carlton JM

    更新日期:2013-09-01 00:00:00

  • Bayesian melding for estimating uncertainty in national HIV prevalence estimates.

    abstract:OBJECTIVE:To construct confidence intervals for HIV prevalence in countries with generalised epidemics. METHODS:In the Bayesian melding approach, a sample of country-specific epidemic curves describing HIV prevalence over time is derived based on time series of antenatal clinic prevalence data and general information ...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章,多中心研究

    doi:10.1136/sti.2008.029991

    authors: Alkema L,Raftery AE,Brown T

    更新日期:2008-08-01 00:00:00

  • A new infectious disease model for estimating and projecting HIV/AIDS epidemics.

    abstract:OBJECTIVES:As the global HIV pandemic enters its fourth decade, countries have collected longer time series of surveillance data, and the AIDS-specific mortality has been substantially reduced by the increasing availability of antiretroviral treatment. A refined model with a greater flexibility to fit longer time serie...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章

    doi:10.1136/sextrans-2012-050689

    authors: Bao L

    更新日期:2012-12-01 00:00:00

  • Condom deserts: geographical disparities in condom availability and their relationship with rates of sexually transmitted infections.

    abstract:BACKGROUND:Identifying predictors that contribute to geographical disparities in sexually transmitted infections (STIs) is necessary. This study assesses the spatial relationship between condom availability to locations of STIs in order to better understand these geographical disparities. OBJECTIVES:We conducted a con...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章

    doi:10.1136/sextrans-2015-052144

    authors: Shacham E,Nelson EJ,Schulte L,Bloomfield M,Murphy R

    更新日期:2016-05-01 00:00:00

  • A new multiplex real-time PCR test for HSV1/2 and syphilis: an evaluation of its impact in the laboratory and clinical setting.

    abstract:OBJECTIVES:To develop, evaluate and implement a new multiplex real-time PCR test for the detection of herpes simplex virus (HSV)1, HSV2 and syphilis in a single sample using a single test. METHODS:A multiplex real-time PCR test detecting HSV1, HSV2 and Treponema pallidum was designed, validated and evaluated for a per...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章

    doi:10.1136/sti.2009.040451

    authors: Scott LJ,Gunson RN,Carman WF,Winter AJ

    更新日期:2010-12-01 00:00:00

  • Sociodemographic and behavioural factors associated with testing for HIV and STIs in a US nationwide sample of transgender men who have sex with men.

    abstract:OBJECTIVES:Transgender men who have sex with men (TMSM) represent an understudied population in relation to screening for HIV and sexually transmitted infections (STIs). We examined HIV and STI testing prevalence among TMSM along with the factors associated with testing in a diverse US nationwide sample of TMSM. METHO...

    journal_title:Sexually transmitted infections

    pub_type: 杂志文章

    doi:10.1136/sextrans-2020-054474

    authors: Antebi-Gruszka N,Talan AJ,Reisner SL,Rendina HJ

    更新日期:2020-09-01 00:00:00