Abstract:
:Recent advances in genetic characterisation of Trichomonas vaginalis isolates show that the extensive clinical variability in trichomoniasis and its disease sequelae are matched by significant genetic diversity in the organism itself, suggesting a connection between the genetic identity of isolates and their clinical manifestations. Indeed, a high degree of genetic heterogeneity in T vaginalis isolates has been observed using multiple genotyping techniques. A unique two-type population structure that is both local and global in distribution has been identified, and there is evidence of recombination within each group, although sexual recombination between the groups appears to be constrained. There is conflicting evidence in these studies for correlations between T vaginalis genetic identity and clinical presentation, metronidazole susceptibility, and the presence of T vaginalis virus, underscoring the need for adoption of a common standard for genotyping the parasite. Moving forward, microsatellite genotyping and multilocus sequence typing are the most robust techniques for future investigations of T vaginalis genotype-phenotype associations.
journal_name
Sex Transm Infectjournal_title
Sexually transmitted infectionsauthors
Meade JC,Carlton JMdoi
10.1136/sextrans-2013-051098subject
Has Abstractpub_date
2013-09-01 00:00:00pages
444-8issue
6eissn
1368-4973issn
1472-3263pii
sextrans-2013-051098journal_volume
89pub_type
杂志文章,评审abstract:OBJECTIVES:While genitourinary medicine (GUM) records have historically been kept separate from other medical data, patient information is increasingly shared across the NHS. There are advantages to this in GUM: GPs are increasingly involved in delivering targets for STI screening and sexual health services. We ascerta...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sti.2007.026922
更新日期:2008-02-01 00:00:00
abstract:OBJECTIVES:In addition to researcher-designed sampling biases, population-representative surveys for biomarker measurement of STIs often have substantial missingness due to non-contact, non-consent and other study-implementation issues. STI prevalence estimates may be biased if this missingness is related to STI risk. ...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sextrans-2019-054342
更新日期:2020-11-01 00:00:00
abstract:BACKGROUND:Gonorrhoea is increasing among men who have sex with men (MSM). We aimed to determine whether Listerine, a commercial mouthwash product, has an inhibitory effect against Neisseria gonorrhoeae in a randomised controlled trial (RCT) and an in vitro study, and therefore may be a potentially useful agent for gon...
journal_title:Sexually transmitted infections
pub_type: 杂志文章,随机对照试验
doi:10.1136/sextrans-2016-052753
更新日期:2017-03-01 00:00:00
abstract:OBJECTIVES:To characterise all isolates with reduced susceptibility or resistance to ciprofloxacin received by the Scottish Neisseria gonorrhoeae Reference Laboratory (SNGRL) in 2002 using N gonorrhoeae multi-antigen sequence typing (NG-MAST); to compare NG-MAST with conventional typing and to describe the epidemiology...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sti.2004.013565
更新日期:2005-10-01 00:00:00
abstract:OBJECTIVE:To describe the impact of a repeating behavioural intervention focused on preventive education and provision of STD testing and treatment services to female sex workers. METHODS:A prospective cohort study of 966 sex workers (first of its kind in China) was conducted in Guangzhou from March 1998 to October 19...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sti.78.2.110
更新日期:2002-04-01 00:00:00
abstract:BACKGROUND:Although physician recommendation is one of the strongest predictors of human papillomavirus (HPV) vaccination, it is unclear for whom physicians are recommending the vaccine. To help guide intervention efforts, this study investigated predictors of participant-reported physician recommendation for HPV vacci...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sextrans-2015-052088
更新日期:2016-03-01 00:00:00
abstract:OBJECTIVES:Recently marketed nucleic acid amplification tests (NAAT) for the detection of Neisseria gonorrhoeae (NG) have improved specificity over previous generation assays. A study to assess the necessity for confirmation of Roche cobas 4800 NG positive samples was undertaken by the Public Health Wales Microbiology ...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sextrans-2013-051410
更新日期:2014-06-01 00:00:00
abstract:OBJECTIVES:To determine the prevalence of urethritis pathogens amongst male symptomatic urethritis (MUS) patients, genital ulcer (GUS) patients without urethritis symptoms and men requesting HIV testing at a voluntary counselling and testing (VCT) clinic. METHODS:A prospective study was conducted in Johannesburg, Sout...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sti.2007.028464
更新日期:2008-08-01 00:00:00
abstract:OBJECTIVES:To examine the policy and practice of HIV testing in genitourinary medicine clinics in the United Kingdom. DESIGN:All 176 consultants in charge of genitourinary medicine clinics in the United Kingdom were sent a policy and practice questionnaire. A self selected group of 53 clinics conducted a retrospective...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sti.76.4.307
更新日期:2000-08-01 00:00:00
abstract::We aimed to study the prevalence, characteristics and risk factors of asymptomatic sexually transmitted infections (STIs) in HIV-infected men who have sex with men (MSM). We conducted a prospective cross-sectional study, including asymptomatic HIV-infected MSM attending regular visits between December 2014 and Decembe...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sextrans-2020-054560
更新日期:2020-08-04 00:00:00
abstract::The distribution of HIV-1 subtypes in a population tracks the spread and evolution of the epidemic. This study is a systematic review of all available evidence on HIV-1 molecular epidemiology and subtype distribution in the Middle East and North Africa. Sources of data included Medline and various institutional docume...
journal_title:Sexually transmitted infections
pub_type: 杂志文章,评审
doi:10.1136/sti.2010.043711
更新日期:2011-03-01 00:00:00
abstract:OBJECTIVES:HIV-infected men who have sex with men (HIV-MSM) are at high risk of hepatitis C virus (HCV) infection. This study aimed to compare risk factors between HIV-MSM coinfected with HCV and those who are not, in a national representative survey conducted in France. METHODS:The ANRS VESPA2 survey (April 2011-Janu...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sextrans-2014-051542
更新日期:2015-02-01 00:00:00
abstract:BACKGROUND:Poor knowledge regarding STI and HIV transmission, testing and treatment among men who have sex with men (MSM) may be contributing to their disproportionate burden of STIs. However, factors which predispose MSM to having this low knowledge are less understood. AIM:The aim of this study was to identify facto...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sextrans-2020-054469
更新日期:2020-10-26 00:00:00
abstract::The primary objectives of this study were to assess the changing demographic characteristics of female sex workers (FSWs) in the urban Bangalore district, India, and trends in programme coverage, HIV/sexually transmitted infection prevalence rates and condom use. Cross-sectional, integrated behavioural and biological ...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sextrans-2013-051203
更新日期:2013-12-01 00:00:00
abstract::Azithromycin 1 g immediately and doxycycline 100 mg twice daily have good antimicrobial activity against Chlamydia trachomatis and treatment studies have demonstrated a >95% microbiological cure at 2-5 weeks, with antimicrobial resistance being rarely reported. Recently an 8% (95%, CI 5% to 11%) failure rate was obser...
journal_title:Sexually transmitted infections
pub_type: 杂志文章,评审
doi:10.1136/sti.2005.019158
更新日期:2006-08-01 00:00:00
abstract:BACKGROUND:Anogenital warts (AGWs, condylomata acuminata) are among the most common STIs and may severely impact quality of life (QoL). Available treatment options are characterised by a high proportion of non-responders and recurrences. OBJECTIVE:To systematically review and meta-analyse the available evidence from r...
journal_title:Sexually transmitted infections
pub_type: 杂志文章,meta分析,评审
doi:10.1136/sextrans-2016-052768
更新日期:2017-05-01 00:00:00
abstract:OBJECTIVE:To summarise evidence on the attributable risk of infertility after chlamydial infection in women. METHODS:Twelve databases were searched, limited to peer-reviewed literature published from January 1970 to September 2007. Conference abstracts and reference lists from reviews published since 2000 and from key...
journal_title:Sexually transmitted infections
pub_type: 杂志文章,评审
doi:10.1136/sti.2007.026047
更新日期:2008-06-01 00:00:00
abstract:OBJECTIVES:To assess the feasibility and utility of sentinel laboratory surveillance of HIV testing as a tool for understanding patterns and trends in HIV testing in a range of healthcare services. METHODS:Data on all anti-HIV antibody tests carried out by the Leeds Teaching Hospital Trust laboratory over a 12-month p...
journal_title:Sexually transmitted infections
pub_type: 杂志文章,多中心研究
doi:10.1136/sti.2009.041293
更新日期:2010-10-01 00:00:00
abstract:OBJECTIVES:The principal aim of the study was to verify whether HPV infection in healthy women, as determined by HPV DNA detection, was associated with an increased risk of development of cervical lesions. METHODS:Cervical smears collected at enrolment into the prospective study conducted in Prague during 1975-83 were...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sti.79.3.191
更新日期:2003-06-01 00:00:00
abstract:OBJECTIVES:To describe the early impact of COVID-19 and associated control measures on the sexual behaviour of pre-exposure prophylaxis (PrEP) users in Wales. METHODS:Data were obtained from an ecological momentary assessment study of PrEP use and sexual behaviour. Participants were individuals accessing PrEP through ...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sextrans-2020-054598
更新日期:2020-09-23 00:00:00
abstract:OBJECTIVE:To estimate the cumulative incidence of severe complications associated with genital chlamydia infection in the general female population. METHODS:The Uppsala Women's Cohort Study was a retrospective population based cohort study in Sweden, linking laboratory, hospital, and population registers. We estimated...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sti.2005.017186
更新日期:2006-06-01 00:00:00
abstract:OBJECTIVE:To describe the impact of HIV on mortality in men and women aged 15-54 in London. DESIGN:Combination of routine mortality statistics with reports of AIDS deaths adjusted for underreporting and change in address from time of report to time of death. Calculation of standardised mortality ratios (SMRs) for male...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sti.75.6.385
更新日期:1999-12-01 00:00:00
abstract:BACKGROUND:Accession of 10 Central and Eastern European (CEE) countries to the E.U. resulted in the largest migratory influx in peacetime British history. No information exists on the sexual behaviour of CEE migrants within the U.K. The aim of this study was to assess the sexual lifestyles and health service needs of t...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sti.2010.047209
更新日期:2011-06-01 00:00:00
abstract:OBJECTIVES:In recent years, studies have demonstrated frequent rectal Chlamydia trachomatis (CT) detection in women, irrespective of reported anal sex or rectal symptoms. However, the clinical relevance and public health implication of rectal CT detection in women remain under debate. Therefore, evaluating CT viability...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sextrans-2019-054002
更新日期:2020-03-01 00:00:00
abstract:OBJECTIVES:This exploratory study compared the frequency of condom use errors and problems between men reporting that condom use for penile-vaginal sex was a mutual decision compared with men making the decision unilaterally. METHODS:Nearly 2000 people completed a web-based questionnaire. A sub-sample of 660 men repor...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sti.2007.027755
更新日期:2008-06-01 00:00:00
abstract::Neurosyphilis and neurological complications from syphilis may be commoner in HIV disease. With outbreaks of early syphilis in HIV positive individuals being observed over recent years, rare neurological manifestations of secondary syphilis will be observed more commonly. We describe a case of an HIV positive individu...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sti.2004.011668
更新日期:2005-04-01 00:00:00
abstract:OBJECTIVES:Treatment of Neisseria gonorrhoeae is threatened by the emergence of antimicrobial resistance. We analysed data from the Gonococcal Resistance to Antimicrobials Surveillance Programme (GRASP) in England and Wales to identify groups most at risk of reduced susceptibility to the currently recommended first-lin...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sextrans-2016-052583
更新日期:2017-02-01 00:00:00
abstract:OBJECTIVE:To examine the frequency of three sexual behaviours from the most active to the least active members of the population in various subpopulations using measures of inequality. METHODS:Data from a US national probability sample of the population aged 15-44 years (National Survey of Family Growth) were used. Gi...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sti.2010.042283
更新日期:2010-12-01 00:00:00
abstract:OBJECTIVES:To identify point-of-care (POC) and rapid nucleic acid amplification techniques (NAATs) for the diagnosis of chlamydia and gonorrhoea and assess their utility. METHODS:Literature search for available POC and rapid NAATs. The performance from the best-performing assays were applied hypothetically to patients...
journal_title:Sexually transmitted infections
pub_type: 杂志文章,评审
doi:10.1136/sextrans-2014-051997
更新日期:2015-12-01 00:00:00
abstract:OBJECTIVES:To understand the factors associated with knowledge of non-occupational post-exposure prophylaxis (nPEP) and pre-exposure prophylaxis (PrEP), bathhouse patrons in New York City (NYC) were surveyed. METHODS:554 men who have sex with men (MSM) at two NYC bathhouses were given a standardised survey focused on ...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sti.2010.046284
更新日期:2011-06-01 00:00:00