Abstract:
OBJECTIVES:To describe the early impact of COVID-19 and associated control measures on the sexual behaviour of pre-exposure prophylaxis (PrEP) users in Wales. METHODS:Data were obtained from an ecological momentary assessment study of PrEP use and sexual behaviour. Participants were individuals accessing PrEP through the National Health Service (NHS) sexual health clinics across four health boards in Wales. Weekly data documenting condomless sex in the preceding week were analysed between 03/02/2020 and 10/05/2020. The introduction of social distancing measures and changes to sexual health clinics in Wales occurred on the week starting 16/03/2020. Two-level logistic regression models were fitted to condomless sex (yes/no) over time, included an indicator for the week starting 16/03/2020, and were extended to explore differential associations by relationship status and sexual health clinic. RESULTS:Data were available from 56 participants and included 697 person-weeks (89% of the maximum number that could have been obtained). On average, 42% of participants reported condomless sex in the period prior to the introduction of social distancing measures and 20% reported condomless sex after (OR=0.16, 95% CI 0.07 to 0.37, p<0.001). There was some evidence to suggest that this association was moderated by relationship status (OR for single participants=0.09, 95% CI 0.06 to 0.23; OR for not single participants=0.46, 95% CI 0.16 to 1.25). CONCLUSIONS:The introduction of social distancing measures and changes to PrEP services across Wales was associated with a marked reduction in reported instances of condomless sexual intercourse among respondents, with a larger reduction in those who were single compared with those who were not. The long-term impact of COVID-19 and associated control measures on this population's physical and mental health and well-being requires close examination.
journal_name
Sex Transm Infectjournal_title
Sexually transmitted infectionsauthors
Gillespie D,Knapper C,Hughes D,Couzens Z,Wood F,de Bruin M,Ma R,Jones AT,Williams A,Hood Kdoi
10.1136/sextrans-2020-054598subject
Has Abstractpub_date
2020-09-23 00:00:00eissn
1368-4973issn
1472-3263pii
sextrans-2020-054598pub_type
杂志文章abstract:OBJECTIVE:HIV transmission is ongoing among men who have sex with men (MSM) in the UK. Sex without a condom (condomless sex, CLS) is the main risk factor. We investigated the prevalence of and factors associated with types of CLS. METHODS:Cross-sectional questionnaire study in UK HIV clinics in 2011/2012 (ASTRA). MSM ...
journal_title:Sexually transmitted infections
pub_type: 杂志文章,多中心研究
doi:10.1136/sextrans-2016-053029
更新日期:2017-12-01 00:00:00
abstract:OBJECTIVES:To assess HIV and syphilis prevalence, HIV-related behaviours and testing for HIV in female sex workers (FSW) in Sudan. DESIGN:Bio-behavioural surveys using respondent-driven sampling were carried out among FSW in the capital cities of 14 states in Sudan in 2011-2012. HIV and syphilis testing was done by ra...
journal_title:Sexually transmitted infections
pub_type: 杂志文章,多中心研究
doi:10.1136/sextrans-2013-051097
更新日期:2013-11-01 00:00:00
abstract:OBJECTIVE:To develop a risk assessment algorithm that will increase the identification and treatment of women with cervical infection in rural Haiti. METHODS:Study participants were randomly selected from new patients who accessed services at a women's health clinic in rural Haiti between June 1999 and December 2002. ...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sti.2005.016733
更新日期:2006-04-01 00:00:00
abstract:OBJECTIVES:To collect and analyse published and unpublished surveillance and research data on the prevalence of same sex sexual activity among male adults (including male-to-female transgenders and sex workers) in low and middle income countries. METHODS:Key indicators were operationalised (ever sex with a man, sex wi...
journal_title:Sexually transmitted infections
pub_type: 杂志文章,评审
doi:10.1136/sti.2005.019489
更新日期:2006-06-01 00:00:00
abstract:OBJECTIVES:Biologically false positive (BFP) reactions are well described in early literature. However, only a few recent reports described the incidence and clinical characteristics of patients with BFP reactions. We reviewed the serological test results of patients tested for syphilis in our hospital in the past deca...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sextrans-2020-054628
更新日期:2020-11-18 00:00:00
abstract:OBJECTIVES:To develop two new models of expedited partner therapy for the UK, and evaluate them for feasibility, acceptability and preliminary outcome estimates to inform the design of a randomised controlled trial (RCT). METHODS:Two models of expedited partner therapy (APTHotline and APTPharmacy), known as 'Accelerat...
journal_title:Sexually transmitted infections
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1136/sti.2010.047258
更新日期:2012-02-01 00:00:00
abstract:BACKGROUND:Gonorrhoea is increasing among men who have sex with men (MSM). We aimed to determine whether Listerine, a commercial mouthwash product, has an inhibitory effect against Neisseria gonorrhoeae in a randomised controlled trial (RCT) and an in vitro study, and therefore may be a potentially useful agent for gon...
journal_title:Sexually transmitted infections
pub_type: 杂志文章,随机对照试验
doi:10.1136/sextrans-2016-052753
更新日期:2017-03-01 00:00:00
abstract:OBJECTIVES:A new molecular test for Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) (GeneXpert CT/NG) has been demonstrated to be as accurate as conventional nucleic acid amplification tests (NAAT), but performance has not been evaluated in routine primary care, performed at the point of care by clinicians. W...
journal_title:Sexually transmitted infections
pub_type: 杂志文章,随机对照试验
doi:10.1136/sextrans-2017-053443
更新日期:2018-08-01 00:00:00
abstract:OBJECTIVES:To review the uptake of a new service for condom provision in the under 16s. METHODS:A retrospective case note review of attenders at an inner London sexual health clinic. RESULTS:The service was audited over a 3 month period in the spring of 2000. There were 97 individual attendances, 94% (92) male and 6%...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sti.77.4.287
更新日期:2001-08-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:The polymer conjugate enhanced enzyme immunoassay (IDEIA) and Cobas Amplicor polymerase chain reaction Chlamydia trachomatis (CT) (Amplicor PCR) are two commonly used assays for the diagnosis of CT infection. The performance of these assays was compared for the diagnosis of genital CT infection am...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sti.2005.015362
更新日期:2006-02-01 00:00:00
abstract:OBJECTIVE:To describe an exercise, the structure and content of which assists medical students to conduct potentially embarrassing conversations concerning sexual health which require expression of empathy, to integrate previous learning, to identify their further learning needs, and to develop and test strategies to m...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sti.78.4.246
更新日期:2002-08-01 00:00:00
abstract:BACKGROUND:'Chemsex' is a colloquial term used in the UK that describes sex under the influence of psychoactive substances (typically crystal methamphetamine, mephedrone and gamma-hydroxybutyric acid (GHB)/gamma-butyrolactone (GBL)). Recently, concern has been raised as to the impact of such behaviour on HIV/sexually t...
journal_title:Sexually transmitted infections
pub_type: 杂志文章,多中心研究
doi:10.1136/sextrans-2015-052052
更新日期:2015-12-01 00:00:00
abstract:OBJECTIVE:To describe patterns of HIV infection among stable sexual partnerships across sub-Saharan Africa (SSA). METHODS:The authors defined measures of HIV discordancy and conducted a comprehensive quantitative assessment of discordancy among stable partnerships in 20 countries in SSA through an analysis of the Demo...
journal_title:Sexually transmitted infections
pub_type: 杂志文章,多中心研究
doi:10.1136/sextrans-2011-050114
更新日期:2012-02-01 00:00:00
abstract:OBJECTIVES:This study describes the differences in sexual behaviour in individuals with genital herpes (GH) during "symptomatic" and "asymptomatic" periods of the disease. METHODS:A cross sectional questionnaire was undertaken by 1193 individuals attending clinics between 1998 and 2001. All participants in this analys...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sti.2004.012989
更新日期:2006-02-01 00:00:00
abstract::Since 2003, an ongoing lymphogranuloma venereum (LGV) proctitis outbreak has been reported in industrialised countries with a new variant designated L2b. Only men who have sex with men (MSM) are affected and most are HIV co-infected; delayed or incorrect diagnoses are frequent. We report a rare clinical case of LGV pr...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sti.2007.025395
更新日期:2007-07-01 00:00:00
abstract:OBJECTIVES:To describe the epidemiology of type specific recurrent genital herpes, and to compare the duration of recurrent genital lesions caused by herpes simplex virus (HSV) types 1 and 2. METHODS:Participants were enrolled at clinics across the United States. Adults suspected of having active genital herpes were e...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sti.79.6.456
更新日期:2003-12-01 00:00:00
abstract:BACKGROUND:Accession of 10 Central and Eastern European (CEE) countries to the E.U. resulted in the largest migratory influx in peacetime British history. No information exists on the sexual behaviour of CEE migrants within the U.K. The aim of this study was to assess the sexual lifestyles and health service needs of t...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sti.2010.047209
更新日期:2011-06-01 00:00:00
abstract:OBJECTIVES:The objective of this retrospective study was to summarise the clinical manifestations of, and to analyse the incidence and risk factors of, Jarisch-Herxheimer reaction (JHR) during the treatment of children with symptomatic congenital syphilis. METHODS:Clinical data of 60 children with clinically and labor...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sextrans-2016-053083
更新日期:2018-12-01 00:00:00
abstract:OBJECTIVES:To determine the prevalence of urethritis pathogens amongst male symptomatic urethritis (MUS) patients, genital ulcer (GUS) patients without urethritis symptoms and men requesting HIV testing at a voluntary counselling and testing (VCT) clinic. METHODS:A prospective study was conducted in Johannesburg, Sout...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sti.2007.028464
更新日期:2008-08-01 00:00:00
abstract:BACKGROUND:Apolipoprotein E is polymorphic in the human population. APOE4 has previously been reported to correlate with symptomatic oral and genital herpes disease. METHODS:APOE was genotyped in 182 subjects with herpes simplex virus (HSV) 2 and in 62 subjects with HSV-1, including 44 subjects with both viral types f...
journal_title:Sexually transmitted infections
pub_type: 杂志文章,多中心研究
doi:10.1136/sti.2009.039735
更新日期:2010-06-01 00:00:00
abstract::Eosinophilic folliculitis (EF) is a chronic, intensely pruritic condition of unknown pathogenesis that causes marked morbidity in those HIV patients whom it affects. There is a wide differential diagnosis of itchy skin conditions in HIV which are amenable to different treatments. It is therefore essential to take a bi...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sti.75.5.291
更新日期:1999-10-01 00:00:00
abstract::Chancroid is a sexually transmitted disease (STD) caused by the Gram negative bacterium Haemophilus ducreyi and is characterised by necrotising genital ulceration which may be accompanied by inguinal lymphadenitis or bubo formation. H ducreyi is a fastidious organism which is difficult to culture from genital ulcer ma...
journal_title:Sexually transmitted infections
pub_type: 杂志文章,评审
doi:10.1136/sti.79.1.68
更新日期:2003-02-01 00:00:00
abstract:OBJECTIVES:This study aimed to describe the epidemiology of HIV infection and sexually transmitted infections (STIs) among persons who attended voluntary counselling and testing (VCT) service for HIV and to assess whether the VCT programme reached the right population at risk in Taiwan. METHODS:From 2006 to 2010, ques...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sextrans-2011-050354
更新日期:2012-12-01 00:00:00
abstract:OBJECTIVE:To determine feasibility, validity, and cost effectiveness of the syndromic approach to male patients with urethral discharge in Bandung, Indonesia. METHODS:The WHO algorithm on urethral discharge with no microscopy available was evaluated. Patients presented with a complaint of urethral discharge and if dis...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:
更新日期:1998-06-01 00:00:00
abstract:OBJECTIVES:Herpes simplex virus-2 (HSV-2) and syphilis are associated with increased risk of HIV, highlighting the importance of understanding their transmission dynamics. In India, most studies of HSV-2 and syphilis incidence are in high-risk populations and may not accurately reflect infectious activity. In this stud...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sextrans-2014-051708
更新日期:2015-08-01 00:00:00
abstract:OBJECTIVES:The objectives of this study were to assess the prevalence of ciprofloxacin-resistant gonorrhoea in two South African cities and to investigate the association between the isolation of ciprofloxacin-resistant Neisseria gonorrhoeae and the HIV serostatus of patients. METHODS:Gonococci were cultured from endo...
journal_title:Sexually transmitted infections
pub_type: 杂志文章,多中心研究
doi:10.1136/sti.2007.029611
更新日期:2008-10-01 00:00:00
abstract:OBJECTIVES:To assess associations between residences location, risky sexual behaviours and sexually transmitted diseases (STDs) among adults living in Guangzhou, China. METHODS:Data were obtained from 751 Chinese adults aged 18-59 years in Guangzhou, China, using stratified random sampling by using spatial epidemiolog...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sextrans-2015-052268
更新日期:2016-06-01 00:00:00
abstract:OBJECTIVES:HIV-infected men who have sex with men (HIV-MSM) are at high risk of hepatitis C virus (HCV) infection. This study aimed to compare risk factors between HIV-MSM coinfected with HCV and those who are not, in a national representative survey conducted in France. METHODS:The ANRS VESPA2 survey (April 2011-Janu...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sextrans-2014-051542
更新日期:2015-02-01 00:00:00
abstract:OBJECTIVE:To assess the validity of sexual behaviour data collected from African adolescents using five methods. METHODS:9280 Tanzanian adolescents participated in a biological marker and face to face questionnaire survey and 6079 in an assisted self-completion questionnaire survey; 74 participated in in-depth intervi...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sti.2004.011924
更新日期:2004-12-01 00:00:00
abstract:BACKGROUND AND HYPOTHESIS:Recently, the world has experienced a rapidly escalating outbreak of infectious syphilis primarily affecting men who have sex with men (MSM); many are taking highly active antiretroviral therapy (HAART) for HIV-1 infection. The prevailing hypothesis is that HAART availability and effectiveness...
journal_title:Sexually transmitted infections
pub_type: 杂志文章,评审
doi:10.1136/sextrans-2016-052870
更新日期:2017-08-01 00:00:00