Methyl-group donors cannot prevent apoptotic death of rat hepatocytes induced by choline-deficiency.

abstract：:Curcumin, the main ingredient of Curcuma longa L., has been used as a spice and as a herbal medicine with different therapeutic characteristics for centuries in Asian countries. This phytochemical has been shown to possess beneficial antiplatelet activity that has introduced it as a promising candidate for the treatme...

journal_title：Journal of cellular biochemistry

authors： Tabeshpour J,Hashemzaei M,Sahebkar A

更新日期：2018-11-01 00:00:00

abstract：:Muscular dystrophies are characterized by continuous cycles of degeneration and regeneration that result in extensive fibrosis and a progressive diminution of muscle mass. Cell surface heparan sulfate proteoglycans are found almost ubiquitously on the surface and in the extracellular matrix (ECM) of mammalian cells. T...

journal_title：Journal of cellular biochemistry

authors： Alvarez K,Fadic R,Brandan E

更新日期：2002-01-01 00:00:00

abstract：:In our previous study, preliminary data indicates that Poria cocos polysaccharides (PCP) shows beneficial hepatoprotection against acetaminophen (APAP)-induced liver injury in mice. However, biological molecular mechanism warrants to be further discussed. In current study, a number of biochemical tests and immunoassay...

journal_title：Journal of cellular biochemistry

authors： Wu K,Guo C,Yang B,Wu X,Wang W

更新日期：2019-05-01 00:00:00

abstract：:Dexmedetomidine, an agonist of alpha2-adrenergic receptors, is used for critically ill patients to induce and maintain sedation and analgesia. Brain ischemia/reperfusion (I/R) usually causes severe neuronal injuries to intensive care unit patients. This study was aimed to evaluate the effects of dexmedetomidine on I/R...

journal_title：Journal of cellular biochemistry

authors： Wu GJ,Chen JT,Tsai HC,Chen TL,Liu SH,Chen RM

更新日期：2017-09-01 00:00:00

abstract：:The aim of the present study was to test the hypothesis that the decreased renal tubular reabsorption of calcium observed in estrogen deficiency is associated with a local regulation of either PTHrP or PTH/PTHrP receptor genes in the kidney. Rats were randomly sham-operated (S) or ovariectomized receiving either vehic...

journal_title：Journal of cellular biochemistry

authors： Cros M,Silve C,Graulet AM,Morieux C,Ureña P,de Vernejoul MC,Bouizar Z

更新日期：1998-07-01 00:00:00

abstract：:microRNA (miRNA) is a family of small, non-coding RNA first discovered as an important regulator of development in Caenorhabditis elegans (C. elegans). Numerous miRNAs have been found in C. elegans, and some of them are well conserved in many organisms. Though, the biologic function of miRNAs in C. elegans was largely...

journal_title：Journal of cellular biochemistry

authors： Liu J,Yang B,Ai J

更新日期：2013-05-01 00:00:00

abstract：:Fracture repair is a complex process involving timed cellular recruitment, gene expression, and synthesis of compounds that regenerate native tissue to restore the mechanical integrity, and thus function of injured bone. While the majority of fractures heal without complication, this takes time and a subset of patient...

journal_title：Journal of cellular biochemistry

authors： Komatsu DE,Warden SJ

更新日期：2010-02-01 00:00:00

abstract：:Oxoglutarate receptor 1 (OXGR1), as one of the intermediates in G protein-coupled receptors (GPCRs), plays a crucial role in the citric acid cycle receptor of α-ketoglutarate and metabolism. GPCR can control the cell proliferation by regulating the downstream signaling of G protein signaling pathways. The PI3K/AKT pat...

journal_title：Journal of cellular biochemistry

authors： Wang Q,Zhang Q,Zhang Y,Zhao X

更新日期：2019-04-01 00:00:00

abstract：:To study hematopoietic differentiation a variety of in vitro systems have been established using hematopoietic precursors derived from various explanted adult and fetal tissues. In this prospective we describe and discuss the potential of a novel system for studying the earliest stages of hematopoietic development. In...

journal_title：Journal of cellular biochemistry

authors： Snodgrass HR,Schmitt RM,Bruyns E

更新日期：1992-07-01 00:00:00

abstract：:We investigated the effects of vitamin D3 on the signaling pathways by prostaglandin E2 (PGE2) in osteoblast-like MC3T3-E1 cells. The pretreatment with 1,25-dihydroxyvitamin D3 (1,25-(OH)2D3), an active form of vitamin D3, significantly inhibited cAMP accumulation induced by 10 microM PGE2 in a dose-dependent manner i...

journal_title：Journal of cellular biochemistry

authors： Tokuda H,Kotoyori J,Suzuki A,Oiso Y,Kozawa O

更新日期：1993-06-01 00:00:00

abstract：:During the past several years, numerous laboratories have reported isolation and purification of proteinase inhibitors from human urine. Many of these molecules were incompletely characterized and some of them may have been artifacts in part because of harsh procedures used for their isolation. Consequently, there is ...

journal_title：Journal of cellular biochemistry

authors： Chawla RK,Lawson DH,Ahmad M,Travis J

更新日期：1992-11-01 00:00:00

abstract：:The MDMX gene product is related to the MDM2 oncoprotein, both of which interact with the p53 tumor suppressor. A novel transcript of the MDMX gene has been previously identified that has a short internal deletion of 68 base pairs, producing a shift in the reading frame after codon 114, resulting in the inclusion of 1...

journal_title：Journal of cellular biochemistry

authors： Rallapalli R,Strachan G,Tuan RS,Hall DJ

更新日期：2003-06-01 00:00:00

abstract：:Published data indicate that the protease-activated receptor (PAR) 2 is involved in the pathogenesis of some cardiovascular diseases; the underlying mechanism is to be further investigated. Ve-cadherin is a critical molecule in maintaining the endothelial barrier integrity. This study aims to investigate the role of P...

journal_title：Journal of cellular biochemistry

authors： Zhang R,Ge J

更新日期：2017-12-01 00:00:00

abstract：:Despite its recognition as the most prevalent HIV associated cancer, speculation still abounds regarding the pathogenesis of AIDS-related Kaposi's sarcoma (AIDS-KS). However, it has been established that both cytokines, e.g. IL-6, and HIV-associated products, e.g., Tat, are integral in AIDS-KS cellular proliferation. ...

journal_title：Journal of cellular biochemistry

authors： Mallery SR,Bailer RT,Hohl CM,Ng-Bautista CL,Ness GM,Livingston BE,Hout BL,Stephens RE,Brierley GP

更新日期：1995-11-01 00:00:00

abstract：:Cervical cancer is a cancer arising from the cervix, and it is the fourth most common cause of death in women. Overexpression of fibronectin 1 (FN1) was observed in many tumors and associated with the survival and metastasis of cancer cells. However, the mechanism by which FN1 promotes cervical cancer cell viability, ...

journal_title：Journal of cellular biochemistry

authors： Zhou Y,Shu C,Huang Y

更新日期：2019-04-11 00:00:00

abstract：:Two monoclonal antibodies that cause changes in the morphology of cultured myogenic cells are described. Antibody JG9 causes myoblasts to round up and causes myotubes to become thin, cable-like structures with multiple round swellings. Antibody JG22 causes both myoblasts and myotubes to become round refractile cells p...

journal_title：Journal of cellular biochemistry

authors： Greve JM,Gottlieb DI

更新日期：1982-01-01 00:00:00

abstract：:Human prostate cancers (PCa) express great variability in their ability to metastasize to bone. The identification of molecules associated with aggressive phenotypes will help to define PCa subsets and will ultimately lead to better treatment strategies. The chemokine stromal-derived factor-1 (SDF-1 or CXCL12) and its...

journal_title：Journal of cellular biochemistry

authors： Sun YX,Wang J,Shelburne CE,Lopatin DE,Chinnaiyan AM,Rubin MA,Pienta KJ,Taichman RS

更新日期：2003-06-01 00:00:00

abstract：:The secretion of matrix metalloproteinase (MMP-9) is stimulated by the glucocorticoid-induced tumor necrosis factor receptor (GITR), a new tumor necrosis factor receptor (TNFR) family, in murine macrophages via an activation of protein kinase C (PKC)delta and phospholipase D (PLD). Secretions of MMP-9 are stimulated b...

journal_title：Journal of cellular biochemistry

authors： Lee HS,Park SY,Lee HW,Choi HS

更新日期：2004-06-01 00:00:00

abstract：:Epidermal Differentiation Complex (EDC) is a gene cluster on human chromosome 1 q21, which comprises genes encoding four protein families: S100, S100 fused (SFTP), small proline-rich region (SPRR) and late cornified envelope (LCE) proteins. Contrary to the latter three families, which group proteins important for skin...

journal_title：Journal of cellular biochemistry

authors： Sobiak B,Graczyk-Jarzynka A,Leśniak W

更新日期：2016-05-01 00:00:00

abstract：:Extracts of thymic lymphoma that are obtained from AKR mice and are kept in the cold for at least several days can induce lipolytic activity in rat adipocyte suspensions. Freshly prepared extracts have low activity but contain a low molecular weight material of less than 10,000 daltons that aggregates on standing in t...

journal_title：Journal of cellular biochemistry

authors： Kitada S,Hays EF,Mead JF,Zabin I

更新日期：1982-01-01 00:00:00

abstract：:Fibronectin (FN) is an extracellular matrix (ECM) glycoprotein that self-assembles into FN fibrils, forming a FN matrix contributing to the stiffness of the ECM. Stromal FN stiffness in cancer has been shown to impact epithelial functions such as migration, cancer metastasis, and epithelial-to-mesenchymal transition. ...

journal_title：Journal of cellular biochemistry

authors： Magdaleno C,House T,Pawar JS,Carvalho S,Rajasekaran N,Varadaraj A

更新日期：2021-01-13 00:00:00

abstract：:ERK1 and ERK2 share a great deal of homology and have been presumed to have similar functions. Available antibodies recognize both isoforms making the elucidation of functional differences challenging. Mitogen-activated protein (MAP) kinase networks are commonly depicted in the literature as linear and sequential phos...

journal_title：Journal of cellular biochemistry

authors： Kang BS,Hwang YJ,Dong Z

更新日期：2017-08-01 00:00:00

abstract：:MicroRNAs (miRNAs) play an important role in the development and progression of non-small cell lung cancer (NSCLC). Recently, several studies have shown that miR-99a is downregulated in various cancers, which can affect tumor initiation and maintenance. Herein, we found that miR-99a was downregulated in NSCLC tissues ...

journal_title：Journal of cellular biochemistry

authors： Yu SH,Zhang CL,Dong FS,Zhang YM

更新日期：2015-02-01 00:00:00

abstract：:During neonatal development, cardiac myocytes undergo a transition from hyperplastic to hypertrophic growth. Whether these cells are terminally differentiated and permanently withdrawn from the cell cycle shortly after birth is controversial. Nevertheless, the clinical observation that functionally significant myocard...

journal_title：Journal of cellular biochemistry

authors： Chim SS,Fung K,Waye MM,Lee C,Tsui SK

更新日期：2000-06-12 00:00:00

abstract：:PKCalpha was found to be expressed (mRNA and protein) throughout the in vitro maturation of primary human erythroblasts but its activity (phosphorylation levels and nuclear localization) was consistently higher in cells derived from human neonatal rather than adult blood. Since the gamma/gamma + beta globin expression...

journal_title：Journal of cellular biochemistry

authors： Di Baldassarre A,Di Rico M,Di Noia A,Bonfini T,Iacone A,Marchisio M,Miscia S,Alfani E,Migliaccio AR,Stamatoyannopoulos G,Migliaccio G

更新日期：2007-05-15 00:00:00

abstract：:Human eosinophil-derived neurotoxin (EDN, RNase2) and eosinophil cationic protein (ECP, RNase3) sequences possess as high as 92% identity in their promoter regions. The major difference within this region is a 34-nucleotide (34-nt) segment appeared only in the edn promoter. In addition, six discrete segments existed i...

journal_title：Journal of cellular biochemistry

authors： Wang HY,Ho PC,Lan CY,Chang MD

更新日期：2009-02-01 00:00:00

abstract：:Vascular smooth muscle cells (SMCs), the major cellular constituent of an artery, synthesize the bulk of fibrillar collagens, including type V/XI, which regulates heterotypic collagen fibril assembly. Basic fibroblast growth factor (bFGF) is a heparin-binding polypeptide growth factor that has been implicated in impor...

journal_title：Journal of cellular biochemistry

authors： Kypreos KE,Sonenshein GE

更新日期：1998-02-01 00:00:00

abstract：:The reactive metabolites of benzo[a]pyrene (B[a]P) and cyclopenta[c,d]pyrene (CPP) induced an accumulation/phosphorylation of p53 in Hepa1c1c7 cells, whereas inhibition of p53 reduced the apoptosis. Judged by the inhibiting effect of wortmannin, phosphatidyl-inositol-3 (PI-3) kinases such as DNA-dependent protein kina...

journal_title：Journal of cellular biochemistry

authors： Solhaug A,Refsnes M,Holme JA

更新日期：2004-12-15 00:00:00

abstract：:Acetaminophen (APAP) is a widely used over-the-counter analgesic and antipyretic. It can cause hepatotoxicity. Recent studies demonstrated that hydrogen sulfide (H2 S) exhibits cell protection in several cell types. This study was designed to investigate whether H 2 S ameliorated APAP-induced acute liver injury and to...

journal_title：Journal of cellular biochemistry

authors： Li X,Lin J,Lin Y,Huang Z,Pan Y,Cui P,Yu C,Cai C,Xia J

更新日期：2019-03-01 00:00:00

abstract：:Perilipin and ADRP, located on the surface of intracellular lipid droplets, are proposed to be involved in adipocyte lipid metabolism. The aim of the present study was to investigate the effect of PKA and PKC activities on the distribution of perilipin and ADRP in primary cultured adrenal cells, and the role of ERK in...

journal_title：Journal of cellular biochemistry

authors： Fong TH,Yang CC,Greenberg AS,Wang SM

更新日期：2002-01-01 00:00:00