Secretions of MMP-9 by soluble glucocorticoid-induced tumor necrosis factor receptor (sGITR) mediated by protein kinase C (PKC)delta and phospholipase D (PLD) in murine macrophage.

abstract：:Wnt/β-catenin signaling regulates various cellular events involved in the proliferation and differentiation and these events are affected sensitively by applying to mechanical stimuli. However, the mechanisms by which mechanical force stimulates cardiomyogenesis are not extensively explored. In this study we investiga...

journal_title：Journal of cellular biochemistry

authors： Heo JS,Lee JC

更新日期：2011-07-01 00:00:00

abstract：:3,6-Anhydro-l-galactose (l-AHG) is a bioactive sugar that is a major component of agarose. Recently, l-AHG was reported to have anti-melanogenic potential in human epidermal melanocytes (HEMs) and B16F10 melanoma cells; however, its underlying molecular mechanisms remain unknown. At noncytotoxic concentrations, l-AHG ...

journal_title：Journal of cellular biochemistry

authors： Kim JH,Kim DH,Cho KM,Kim KH,Kang NJ

更新日期：2018-09-01 00:00:00

abstract：:Serine-threonine protein kinase glycogen synthase kinase (GSK)-3 is involved in regulation of many cell functions, but its role in regulating liver regeneration is unknown. Here we investigated the effects of GSK-3beta inhibition on liver regeneration after partial hepatectomy in the rat. The potent and selective GSK-...

journal_title：Journal of cellular biochemistry

authors： Chen H,Yang S,Yang Z,Ma L,Jiang D,Mao J,Jiao B,Cai Z

更新日期：2007-12-01 00:00:00

abstract：:In previous studies we have shown that all-trans retinoic acid (atRA)-treatment of the atRA-sensitive ovarian carcinoma cell line CA-OV3 repressed AP-1 activity by about 50%, while a similar effect was not observed in the atRA-resistant ovarian carcinoma cell line, SK-OV3. These results suggested that the repression o...

journal_title：Journal of cellular biochemistry

authors： Ramírez CJ,Haberbusch JM,Soprano DR,Soprano KJ

更新日期：2005-09-01 00:00:00

abstract：:Molecular mechanisms responsible for tumor resistance to apoptosis often involve the Fas/FasL pathway. While squamous cell carcinomas of the head and neck (SCCHN) express both Fas and FasL, their resistance to self-induced apoptosis or apoptosis mediated by Fas agonistic antibody (CH-11Ab) was independent of the level...

journal_title：Journal of cellular biochemistry

authors： Wieckowski E,Atarashi Y,Stanson J,Sato TA,Whiteside TL

更新日期：2007-01-01 00:00:00

abstract：:The 68 kDa Src substrate associated during mitosis (Sam68) is an RNA binding protein with Src homology (SH) 2 and 3 domain binding sites. We have recently found that Sam68 is a substrate of the insulin receptor (IR) that translocates from the nucleus to the cytoplasm and that Tyr-phosphorylated Sam68 associates with t...

journal_title：Journal of cellular biochemistry

authors： Najib S,Sánchez-Margalet V

更新日期：2002-01-01 00:00:00

abstract：:Colorectal cancer (CRC) brings more than 600 000 deaths every year around the globe, making itself the third most frequently occurred carcinoma. The great progress human achieved in diagnosis and treatment of various cancers has failed to reverse this trend. Fortunately, growing evidence has implied the relationship b...

journal_title：Journal of cellular biochemistry

authors： Cui G,Zhao H,Li L

更新日期：2020-10-01 00:00:00

abstract：:Allele-specific transcription is a characteristic feature of imprinted genes. Many imprinted genes are also transcribed in a tissue- or cell type-specific manner. Overlapping epigenetic signals must, therefore, modulate allele-specific and tissue-specific expression at imprinted loci. In addition, long-range interacti...

journal_title：Journal of cellular biochemistry

authors： Hanel ML,Lau JC,Paradis I,Drouin R,Wevrick R

更新日期：2005-04-01 00:00:00

abstract：:Previously, we reported that anti-apoptotic Bfl-1 is converted to a pro-apoptotic protein following fusion at its N-terminus with green fluorescent protein (GFP) (GFP-Bfl-1). In this study, we performed a Bfl-1 deletion study in order to elucidate the underlying mechanism of GFP-Bfl-1-induced cell death. We found that...

journal_title：Journal of cellular biochemistry

authors： Yang WS,Ko JK,Park SO,Choi HY,Kim YN,Kim CW

更新日期：2005-04-15 00:00:00

abstract：:Genome-wide screening of the yeast Saccharomyces cerevisiae knockout collection was used to characterize chemical-genetic interactions of cycloheximide (CHX). The results showed that while the act1Δ mutant was the only deletion mutant in the heterozygous essential gene deletion collection that showed hypersensitivity ...

journal_title：Journal of cellular biochemistry

authors： Darvishi E,Woldemichael GM

更新日期：2016-12-01 00:00:00

abstract：:WNT signaling pathways play an important role in both development and disease. By analyzing the signaling capabilities of commercially available WNT3a preparations towards the PI3K/AKT/GSK3 signaling pathway, we discovered unexpected inconsistencies from lot to lot of recombinant WNT3a. We provide evidence that: (1) T...

journal_title：Journal of cellular biochemistry

authors： Cajanek L,Adlerz L,Bryja V,Arenas E

更新日期：2010-12-01 00:00:00

abstract：:Previous studies have demonstrated that germ cells can be derived from mouse embryonic stem cells (ESCs). However, there is still no efficient system, which can visualize the stage of germ cell specification in vitro, and further to identify and enrich germ cells derived from ESCs. Figla (factor in the germline, alpha...

journal_title：Journal of cellular biochemistry

authors： Hu Y,Sun J,Wang J,Wang L,Bai Y,Yu M,Lian Z,Zhang S,Hua J

更新日期：2012-04-01 00:00:00

abstract：:1alpha,25-dihydroxyvitamin D(3) (1alpha,25(OH)(2)D(3)), the active metabolite of vitamin D, mediates many of its effects through the intranuclear vitamin D receptor (VDR, NR1I1), that belongs to the large superfamily of nuclear receptors. Vitamin D receptor can directly regulate gene expression by binding to vitamin D...

journal_title：Journal of cellular biochemistry

authors： Harant H,Spinner D,Reddy GS,Lindley IJ

更新日期：2000-04-01 00:00:00

abstract：:HSP90 chaperones are transducer proteins of many signaling pathways in cells. Using a highly specific inhibitor, geldanamycin (GA), an increasing number of the HSP90 client proteins have been identified. Nevertheless, there is little information on the differential transactivation of the two isoforms of the hsp90 gene...

journal_title：Journal of cellular biochemistry

authors： Chao CC,Sun FC,Wang CH,Lo CW,Chang YS,Chang KC,Chang MD,Lai YK

更新日期：2008-07-01 00:00:00

abstract：AIM:To detect the expression and identify the role of Ribosomal protein S15A (RPS15A) in human breast cancer (BC). METHODS:Immunohistochemistry (IHC) was carried out for detecting the levels of RPS15A protein. Quantitative PCR was used to evaluate the mRNA level of RPS15A in one normal breast and three BC cell lines. ...

journal_title：Journal of cellular biochemistry

authors： Kong L,Wei Q,Hu X,Chen L,Li J

更新日期：2020-01-01 00:00:00

abstract：:We have quantitatively measured gene expression for the sodium-dependent glucose cotransporters 1 and 2 (SGLT1 and SGLT2) in 23 human tissues using the method of real time PCR. As predicted, our results revealed that the expression of SGLT1 was very high in the small intestine (1.2E + 6 molecules/microg total RNA) rel...

journal_title：Journal of cellular biochemistry

authors： Zhou L,Cryan EV,D'Andrea MR,Belkowski S,Conway BR,Demarest KT

更新日期：2003-10-01 00:00:00

abstract：:Multiple sclerosis (MS) is a highly disabling demyelinating disease, which mainly affects young adults and is difficult to cure. Activated microglia may be involved in the process of neuronal cell damage and release inflammatory cytokines to injure neurons. Rapamycin (RAPA), an immunosuppressant, can induce autophagy ...

journal_title：Journal of cellular biochemistry

authors： Xu L,Zhang C,Jiang N,He D,Bai Y,Xin Y

更新日期：2019-04-01 00:00:00

abstract：:We have incorporated antibodies against fibronectin or laminin into liposomes and studied their interaction with insoluble forms of these antigens. The antibodies, after modification by palmitoylchloride, were incorporated into the lipid bilayer by the cholate dialysis method. The antibodies in the liposomes recognize...

journal_title：Journal of cellular biochemistry

authors： Torchilin VP,Klibanov AL,Ivanov NN,Gluckhova MA,Koteliansky VE,Kleinman HK,Martin GR

更新日期：1985-01-01 00:00:00

abstract：:The aim of this study is to observe the changes in osteoprotegerin (OPG) and receptor activator for the nuclear factor-κB ligand (RANKL) in a rabbit model, and to explore the therapeutic effect of tissue engineering bone on femoral head necrosis. A total of 60 rabbits were randomly divided into 5 groups. The necrosis ...

journal_title：Journal of cellular biochemistry

authors： Peng W,Zhang J,Zhang F,Zhao Y,Dong W

更新日期：2018-10-18 00:00:00

abstract：:Efficient catabolism of host-derived compounds is essential for bacterial survival and virulence. While these links in intracellular bacteria are well studied, such studies in extracellular bacteria lag behind, mostly for technical reasons. The field has identified important metabolic pathways, but the mechanisms by w...

journal_title：Journal of cellular biochemistry

authors： Meadows JA,Wargo MJ

更新日期：2014-02-01 00:00:00

abstract：:Perilipin and ADRP, located on the surface of intracellular lipid droplets, are proposed to be involved in adipocyte lipid metabolism. The aim of the present study was to investigate the effect of PKA and PKC activities on the distribution of perilipin and ADRP in primary cultured adrenal cells, and the role of ERK in...

journal_title：Journal of cellular biochemistry

authors： Fong TH,Yang CC,Greenberg AS,Wang SM

更新日期：2002-01-01 00:00:00

abstract：:Cell motility, growth, and proliferation are regulated by adhesion to the extracellular matrix. Detachment of adherent cells from extracellular matrix results in induction of apoptosis ("anoikis"). Transformed cells often show an anchorage-independent growth that enables them to acquire a motile, invasive phenotype. T...

journal_title：Journal of cellular biochemistry

authors： Marco RA,Díaz-Montero CM,Wygant JN,Kleinerman ES,McIntyre BW

更新日期：2003-04-01 00:00:00

abstract：:Members of the transforming growth factor-β (TGF-β) family function through Smad-dependent and Smad-independent pathways. The Smad-dependent pathway is stimulated through the phosphorylation of receptor-regulated Smad (R-Smad) and inhibited through the dephosphorylation of R-Smad or the gene induction of inhibitory Sm...

journal_title：Journal of cellular biochemistry

authors： Katakawa Y,Funaba M,Murakami M

更新日期：2016-08-01 00:00:00

abstract：:MicroRNA-205 (miR-205) is involved in various physiological and pathological processes, but its biological function in follicular atresia remains unclear. In this study, we investigated miR-205 expression in mouse granulosa cells (mGCs) and analyzed its functions in primary mGCs by performing a series of in vitro expe...

journal_title：Journal of cellular biochemistry

authors： Zhang P,Wang J,Lang H,Wang W,Liu X,Liu H,Tan C,Li X,Zhao Y,Wu X

更新日期：2018-12-16 00:00:00

abstract：:Rat liver regeneration after partial hepatectomy (PH) is a good model to study the regulation of cell proliferation. We isolated hepatocytes from regenerating liver at different time points after PH and used microarray Rat Genome 230 2.0 chip to analyze the functional profiles of all up- or down-regulated genes manual...

journal_title：Journal of cellular biochemistry

authors： Jiang Y,Zhang LX,Chang CF,Wang GP,Shi RJ,Yang YJ,Xu CS

更新日期：2011-11-01 00:00:00

abstract：:Chondrocyte differentiation is a fundamental process during endochondral ossification. Several factors regulate maturation via the activity of downstream signaling pathways that target specific transcription factors and regulate chondrocyte-specific genes. In this study, we investigated the mechanisms involved in the ...

journal_title：Journal of cellular biochemistry

authors： Drissi MH,Li X,Sheu TJ,Zuscik MJ,Schwarz EM,Puzas JE,Rosier RN,O'Keefe RJ

更新日期：2003-12-15 00:00:00

abstract：:Tangeretin, a citrus flavonoid extracted from the peel of citrus fruits, was reported to possess antiasthmatic, antioxidant, anti-inflammatory, and neuroprotective properties. However, the effect of tangeretin on human brain microvascular endothelial cells (HBMECs) has not been examined. This study was designed to inv...

journal_title：Journal of cellular biochemistry

authors： Wu C,Zhao J,Chen Y,Li T,Zhu R,Zhu B,Zhang Y

更新日期：2019-04-01 00:00:00

abstract：:With a signal trap method, we previously identified stromal interaction molecule (STIM: originally named as SIM) as a protein, which has a signal peptide in 1996. However, recent works have accumulated evidences that STIM1 and STIM2 reside in endoplasmic reticulum (ER) and that both mainly sense ER Ca(2+) depletion, w...

journal_title：Journal of cellular biochemistry

authors： Saitoh N,Oritani K,Saito K,Yokota T,Ichii M,Sudo T,Fujita N,Nakajima K,Okada M,Kanakura Y

更新日期：2011-01-01 00:00:00

abstract：:Polychlorinated biphenyls (PCBs) are ubiquitous environmental contaminants whose effects on biological systems depend on the number of and the positions of the chlorine substitutions. In the present study we examined the estrogenicity of the fully ortho-substituted PCB, 2,2',6,6'-tetrachlorobiphenyl (2,2',6,6'-TeCB). ...

journal_title：Journal of cellular biochemistry

authors： Arcaro KF,Yi L,Seegal RF,Vakharia DD,Yang Y,Spink DC,Brosch K,Gierthy JF

更新日期：1999-01-01 00:00:00

abstract：:This study aims to explore the effect of miR-330 targeting VAV1 on amyloid β-protein (Aβ) production, oxidative stress (OS), and mitochondrial dysfunction in Alzheimer's disease (AD) mice through the MAPK signaling pathway. Putative targeted gene of miR-330 was performed by a miRNA target prediction website and dual-l...

journal_title：Journal of cellular biochemistry

authors： Zhou Y,Wang ZF,Li W,Hong H,Chen J,Tian Y,Liu ZY

更新日期：2018-07-01 00:00:00