Abstract:
:Efficient catabolism of host-derived compounds is essential for bacterial survival and virulence. While these links in intracellular bacteria are well studied, such studies in extracellular bacteria lag behind, mostly for technical reasons. The field has identified important metabolic pathways, but the mechanisms by which they impact infection and in particular, establishing the importance of a compound's catabolism versus alternate metabolic roles has been difficult. In this review we will examine evidence for catabolism during extracellular bacterial infections in animals and known or potential roles in virulence. In the process, we point out key gaps in the field that will require new or newly adapted techniques.
journal_name
J Cell Biochemjournal_title
Journal of cellular biochemistryauthors
Meadows JA,Wargo MJdoi
10.1002/jcb.24664subject
Has Abstractpub_date
2014-02-01 00:00:00pages
217-23issue
2eissn
0730-2312issn
1097-4644journal_volume
115pub_type
杂志文章abstract::We previously identified human CAP, a homolog of the yeast adenylyl cyclase-associated protein. Previous studies suggest that the N-terminal and C-terminal domains of CAP have distinct functions. We have explored the interactions of human CAP with various proteins. First, by performing yeast two-hybrid screens, we hav...
journal_title:Journal of cellular biochemistry
pub_type: 杂志文章
doi:10.1002/(SICI)1097-4644(19960601)61:3%3C459::AID-J
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pub_type: 杂志文章,评审
doi:10.1002/jcb.20704
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doi:10.1002/jcb.22759
更新日期:2010-10-15 00:00:00
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更新日期:2014-03-01 00:00:00
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更新日期:2001-01-01 00:00:00
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journal_title:Journal of cellular biochemistry
pub_type: 杂志文章
doi:10.1002/jcb.24172
更新日期:2012-09-01 00:00:00
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journal_title:Journal of cellular biochemistry
pub_type: 杂志文章
doi:10.1002/jcb.29535
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journal_title:Journal of cellular biochemistry
pub_type: 杂志文章,评审
doi:10.1002/jcb.240510109
更新日期:1993-01-01 00:00:00
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journal_title:Journal of cellular biochemistry
pub_type: 杂志文章
doi:10.1002/jcb.20357
更新日期:2005-04-01 00:00:00
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journal_title:Journal of cellular biochemistry
pub_type: 杂志文章
doi:10.1002/jcb.240440302
更新日期:1990-11-01 00:00:00
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更新日期:2018-11-28 00:00:00
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pub_type: 杂志文章
doi:10.1002/jcb.27426
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journal_title:Journal of cellular biochemistry
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更新日期:2018-08-01 00:00:00
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journal_title:Journal of cellular biochemistry
pub_type: 杂志文章
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更新日期:2019-04-01 00:00:00
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pub_type: 杂志文章
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