WNT unrelated activities in commercially available preparations of recombinant WNT3a.

abstract：:Extracellular matrix metalloproteinases (MMPs) are activated in dilated cardiomyopathic (DCM) hearts [Tyagi et al. (1996): Mol Cell Biochem 155:13-21]. To examine whether the MMP activation is occurring at the gene expression level, we performed differential display mRNA analysis on tissue from six dilated cardiomyopa...

journal_title：Journal of cellular biochemistry

authors： Tyagi SC,Kumar S,Voelker DJ,Reddy HK,Janicki JS,Curtis JJ

更新日期：1996-11-01 00:00:00

abstract：:Accumulating studies indicates that circular RNAs (circRNAs) play an imperative role in modulating cancer progression and metastasis. In the previous study, elevated circ_0029426 was first observed in glioblastoma (GBM) tissues compared with normal tissues by circRNA microarray. Our aim is to study the function and me...

journal_title：Journal of cellular biochemistry

authors： Zhang G,Sun W,Zhu L,Feng Y,Wu L,Li T

更新日期：2019-06-01 00:00:00

abstract：:The pathways of transduction of oxidative stress signals have been studied using the Jurkat T cell model. The oxidative stress was induced by exposure of the cells to 100 microM H(2)O(2). DNA damage was detected within 15 min after commencement of treatment. DNA damage repair occurred within about 1 h in cells exposed...

journal_title：Journal of cellular biochemistry

authors： Chiaramonte R,Bartolini E,Riso P,Calzavara E,Erba D,Testolin G,Comi P,Sherbet GV

更新日期：2001-01-01 00:00:00

abstract：:The four-subunit protease complex γ-secretase cleaves many single-pass transmembrane (TM) substrates, including Notch and β-amyloid precursor protein to generate amyloid-β (Aβ), central to Alzheimer's disease. Two of the subunits anterior pharynx-defective 1 (APH-1) and presenilin (PS) exist in two homologous forms AP...

journal_title：Journal of cellular biochemistry

authors： Dehury B,Kepp KP

更新日期：2021-01-01 00:00:00

abstract：:The phenotypic modulation of VSMCs is a key cellular event driving neointimal formation and vascular remodeling. As a multifaceted cytokine of cell-mediated immunity, IFN-γ has been shown to play a critical role in the pathogenesis of vascular proliferative diseases. Although the important function of IFN-γ on regulat...

journal_title：Journal of cellular biochemistry

authors： Wang K,Li W,Yu Q,Guo B,Yang B,Zhang C,Li M,Li J,Hu S,Zheng Q,Song Z

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:Gram-negative bacterium, Helicobacter pylori is notorious for various pathologies like peptic ulcers, gastritis, functional dyspepsia, and various cancers. METHODS:Systemic effects of its toxins have led scientists' attention toward the extragastric pathologies associated with it. To date, it has been shown...

journal_title：Journal of cellular biochemistry

authors： Zendehdel A,Roham M

更新日期：2019-08-01 00:00:00

abstract：:Osteoclasts are macrophage-derived polykaryons that degrade bone in an acidic extracellular space. This differentiation includes expression of proteinases and acid transport proteins, cell fusion, and bone attachment, but the sequence of events is unclear. We studied two proteins expressed at high levels only in the o...

journal_title：Journal of cellular biochemistry

authors： Blair HC,Sidonio RF,Friedberg RC,Khan NN,Dong SS

更新日期：2000-06-12 00:00:00

abstract：:The bone marrow provides a protective environment for acute myeloid leukemia (AML) cells that often allows leukemic stem cells to survive standard chemotherapeutic regimens. Targeting these leukemic stem cells within the bone marrow is critical for preventing relapse. We recently demonstrated that SDF-1, a chemokine a...

journal_title：Journal of cellular biochemistry

authors： Kremer KN,Dudakovic A,McGee-Lawrence ME,Philips RL,Hess AD,Smith BD,van Wijnen AJ,Karp JE,Kaufmann SH,Westendorf JJ,Hedin KE

更新日期：2014-06-01 00:00:00

abstract：:Taxol, a microtubule stabilizing agent, has been extensively investigated for its antitumor activity. The cytotoxic effect of taxol is generally attributed to its antimicrotubule activity and is believed to be cell cycle dependent. Herein, we report that taxol induces hyperphosphorylation and reorganization of the vim...

journal_title：Journal of cellular biochemistry

authors： Chu JJ,Chen KD,Lin YL,Fei CY,Chiang AS,Chiang CD,Lai YK

更新日期：1998-03-15 00:00:00

abstract：:The perinucleolar compartment (PNC) is a distinct nuclear body that localizes to the nucleolar periphery. The PNC is predominantly found in cancer cells, and recent evidence suggests that PNC prevalence can be a pan-cancer marker for tumors of solid tissue origin. The PNC is a heritable structure enriched with newly t...

journal_title：Journal of cellular biochemistry

authors： Pollock C,Huang S

更新日期：2009-05-15 00:00:00

abstract：:Extracellular matrix (ECM) accumulation plays a key role in the progression of bladder outlet obstruction (BOO). Muscarinic receptors have been widely reported to serve as pivotal regulators in lung tissue remodeling. However, the influence of them on human bladder smooth muscle cells (HBSMCs) and the underlying molec...

journal_title：Journal of cellular biochemistry

authors： Chen S,Liao B,Jin X,Wei T,He Q,Lin Y,Ai J,Gong L,Li H,Wang K

更新日期：2020-11-01 00:00:00

abstract：:In order to assess, in a controlled in vitro model, the differentiation potential of adult bone marrow derived stem cells we have developed a coculture procedure using adult rat cardiomyocytes and mesenchymal stem cells (MSCs) from transgenic GFP positive rats. We investigated in the cocultured MSCs the time course of...

journal_title：Journal of cellular biochemistry

authors： Gallo MP,Ramella R,Alloatti G,Penna C,Pagliaro P,Marcantoni A,Bonafé F,Losano G,Levi R

更新日期：2007-01-01 00:00:00

abstract：:Gastrokine 1 (GKN1) plays an important role in the gastric mucosal defense mechanism and also acts as a functional gastric tumor suppressor. In this study, we examined the effect of GKN1 on the expression of inflammatory mediators, including NF-κB, COX-2, and cytokines in GKN1-transfected AGS cells and shGKN1-transfec...

journal_title：Journal of cellular biochemistry

authors： Yoon JH,Cho ML,Choi YJ,Back JY,Park MK,Lee SW,Choi BJ,Ashktorab H,Smoot DT,Nam SW,Lee JY,Park WS

更新日期：2013-08-01 00:00:00

abstract：:Colorectal cancer (CRC) is known as the third most common and fourth leading cancer associated death worldwide. The occurrence of metastasis has remained as a critical challenge in CRC, so that distant metastasis (mostly to the liver) has been manifested in about 20%-25% of patients. Several screening approaches have ...

journal_title：Journal of cellular biochemistry

authors： Sarvizadeh M,Ghasemi F,Tavakoli F,Sadat Khatami S,Razi E,Sharifi H,Biouki NM,Taghizadeh M

更新日期：2019-06-01 00:00:00

abstract：:Formyl peptide receptors (FPRs) are a family of classical chemoattractant receptors. Although FPRs are mainly expressed in phagocytic innate immune cells including monocytes/macrophages and neutrophils, recent reports demonstrated that additional different cell types such as T-lymphocytes and several non-immune cells ...

journal_title：Journal of cellular biochemistry

authors： Lee HY,Lee M,Bae YS

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:Expression of forkhead box (FOX) superfamily members has been shown to be decreased in cancer, which was linked to poor prognosis of patients. The aim of this study was to investigate the expression of a new FOX superfamily member, FOXS1, in gastric cancer, and the influence of FOXS1 overexpression on the tu...

journal_title：Journal of cellular biochemistry

authors： Lu Q,Ma X,Li Y,Song W,Zhang L,Shu Y,Wan B

更新日期：2019-03-01 00:00:00

abstract：:As a de-ubiquitin enzyme, ubiquitin C-terminal hydrolase (UCH)-L1 has been shown to be overexpressed in several human cancers. However, the function of UCH-L1 in invasion of breast cancers is still unclear. Here we report that the expression of UCH-L1 is significantly higher in cancer cells with higher invasive abilit...

journal_title：Journal of cellular biochemistry

authors： Luo Y,He J,Yang C,Orange M,Ren X,Blair N,Tan T,Yang JM,Zhu H

更新日期：2018-01-01 00:00:00

abstract：:Pancreatic adenocarcinomas induced in Syrian hamsters by treatment with N-nitrosobis(2-oxopropyl) amine express blood group A antigen, which is absent in normal pancreatic cells. On membrane glycoproteins purified from tumors, blood group A antigen has been found to be expressed on multiantennary Asn-linked complex gl...

journal_title：Journal of cellular biochemistry

authors： Hirota M,Mogaki M,Pour PM,Chaney WG

更新日期：1992-09-01 00:00:00

abstract：:The bone marrow stroma contains pre-adipocyte cells which are part of the hemopoietic microenvironment. Cloned stromal cell lines differ both in their ability to support myeloid and lymphoid development and in their ability to undergo adipocyte differentiation in vitro. These processes have been examined in the +/+2.4...

journal_title：Journal of cellular biochemistry

authors： Gimble JM,Youkhana K,Hua X,Bass H,Medina K,Sullivan M,Greenberger J,Wang CS

更新日期：1992-09-01 00:00:00

abstract：:Inverted repeats occur nonrandomly in the DNA of most organisms. Stem-loops and cruciforms can form from inverted repeats. Such structures have been detected in pro- and eukaryotes. They may affect the supercoiling degree of the DNA, the positioning of nucleosomes, the formation of other secondary structures of DNA, o...

journal_title：Journal of cellular biochemistry

authors： Pearson CE,Zorbas H,Price GB,Zannis-Hadjopoulos M

更新日期：1996-10-01 00:00:00

abstract：:Adamts17 is a member of a family of secreted metalloproteinases. In this report, we show that knockdown of Adamts17 expression induces apoptosis and inhibits breast cancer cell growth. Adamts17 expression can rapidly be induced by estrogens. siRNA knockdown of Sp1 or Myc demonstrated that Sp1 is required to induce Ada...

journal_title：Journal of cellular biochemistry

authors： Jia Z,Gao S,M'Rabet N,De Geyter C,Zhang H

更新日期：2014-10-01 00:00:00

abstract：:In response to tissue injury connective tissue synthesis occurs either normally or abnormally, which is mediated by transforming growth factor-beta (TGF-beta) and other growth factors. This article will be primarily concerned with the response of injured tissues at the gene level of Type I procollagen synthesis in res...

journal_title：Journal of cellular biochemistry

authors： Cutroneo KR

更新日期：2003-09-01 00:00:00

abstract：:Phosphatidylethanolamine-binding protein 4 (PEBP4), a member of the PEBP family, has been reported to play a pivotal role in tumor progression. However, its role in epithelial-to-mesenchymal transition (EMT) in non-small cell lung cancer (NSCLC) cells remains unclear. Here, we investigated the effects and underlying m...

journal_title：Journal of cellular biochemistry

authors： Jian W,Bai Y,Li X,Kang J,Lei Y,Xue Y

更新日期：2019-04-01 00:00:00

abstract：:Although several studies have shown that an induction of insulin-like growth factor (IGF) components occurs during hyperoxia-mediated lung injury, the role of these components in tissue repair is not well known. The present study aimed to elucidate the role of IGF system components in normal tissue remodeling. We used...

journal_title：Journal of cellular biochemistry

authors： Narasaraju TA,Chen H,Weng T,Bhaskaran M,Jin N,Chen J,Chen Z,Chinoy MR,Liu L

更新日期：2006-04-01 00:00:00

abstract：:The cadherin/catenin complex plays a key role in the initiation of cell-cell recognition, and adhesion, and the elaboration of structural and functional organization in multicellular tissues and organs. It is associated with tumor metastasis and also acts as an "invasion suppressor" of cancer cells. Nasopharyngeal car...

journal_title：Journal of cellular biochemistry

authors： Lou PJ,Chen WP,Lin CT,DePhilip RM,Wu JC

更新日期：1999-11-01 00:00:00

abstract：:Entry of β-elemene into various phases of clinical trials advocates its significance as a premium candidate likely to gain access to mainstream medicine. Based on the insights gleaned from decades of research, it seems increasingly transparent that β-elemene has shown significant ability to modulate multiple cell sign...

journal_title：Journal of cellular biochemistry

authors： Qureshi MZ,Attar R,Romero MA,Sabitaliyevich UY,Nurmurzayevich SB,Ozturk O,Wakim LH,Lin X,Ozbey U,Yelekenova AB,Farooqi AA

更新日期：2019-08-01 00:00:00

abstract：:We examined the effects of photobiomodulation (PBM) independently and combined with curcumin on stereological parameters and basic fibroblast growth factor (bFGF), hypoxia-inducible factor-1α (HIF-1α), and stromal cell-derived factor-1α (SDF-1α) gene expressions in an excisional wound model of rats with type one diabe...

journal_title：Journal of cellular biochemistry

authors： Amini A,Soleimani H,Abdollhifar MA,Moradi A,Ghoreishi SK,Chien S,Bayat M

更新日期：2019-10-01 00:00:00

abstract：:Long noncoding RNA (lncRNA) maternally expressed 3 (MEG3) has been implicated as a tumor suppressor gene in several human cancer types. However, little is known regarding its involvement and potential mechanism in human breast cancer. In this study, we explored the effect of MEG3 on the growth of human breast cancer c...

journal_title：Journal of cellular biochemistry

authors： Zhang Y,Wu J,Jing H,Huang G,Sun Z,Xu S

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:Long noncoding RNAs (lncRNAs) regulate gene expression by acting with microRNAs (miRNAs) and indirectly interact with messenger RNA (mRNAs). However, the roles of specific lncRNA and its related competing endogenous RNAs (ceRNA) network in alopecia areata (AA) are not fully understood. METHODS:The blood lnc...

journal_title：Journal of cellular biochemistry

authors： Sheng Y,Ma J,Zhao J,Qi S,Hu R,Yang Q

更新日期：2019-06-01 00:00:00

abstract：:The early 1980s revelation of cis-acting genomic elements, known as transcriptional enhancers, is still regarded as one of the fundamental discoveries in the genomic field. However, only with the emergence of genome-wide techniques has the genuine biological scope of enhancers begun to be fully uncovered. Massive scie...

journal_title：Journal of cellular biochemistry

authors： Blum R

更新日期：2014-11-01 00:00:00