Overexpressed circ_0029426 in glioblastoma forecasts unfavorable prognosis and promotes cell progression by sponging miR-197.

abstract：:In the interphase nucleus of metazoan cells DNA is organized in supercoiled loops anchored to a nuclear matrix (NM). DNA loops are operationally classified in structural and facultative. Varied evidence indicates that DNA replication occurs in replication foci organized upon the NM and that structural DNA loops may co...

journal_title：Journal of cellular biochemistry

authors： Castillo-Mora RC,Aranda-Anzaldo A

更新日期：2012-07-01 00:00:00

abstract：:Extracts of Malus hupehensis (Pamp.) Rehder, containing flavonoids with good antioxidant and antiliver injury properties, possess various biological activities. The aim of this study was to explore the antioxidant activity of these extracts in vitro and in vivo. The antioxidant activity of the extracts was studied usi...

journal_title：Journal of cellular biochemistry

authors： Liu J,Guo D,Fan Y,Sun J,Cheng J,Shi Y

更新日期：2019-02-19 00:00:00

abstract：:Up-regulation of cytosolic phospholipase A(2) (cPLA(2)) by cigarette smoke extract (CSE) may play a critical role in airway inflammatory diseases. However, the mechanisms underlying CSE-induced cPLA(2) expression in human tracheal smooth muscle cells (HTSMCs) were not completely understood. Here, we demonstrated that ...

journal_title：Journal of cellular biochemistry

authors： Cheng SE,Lin CC,Lee IT,Hsu CK,Kou YR,Yang CM

更新日期：2011-02-01 00:00:00

abstract：:Cocultures of rabbit fibroblasts and mouse B-16 melanoma cells produce increased levels of collagenase against type I collagen. This stimulatory effect was also found when fibroblasts were cultured in conditioned media from tumor cells. However, the level of the stimulatory factor in conditioned media was influenced b...

journal_title：Journal of cellular biochemistry

authors： Biswas C

更新日期：1985-01-01 00:00:00

abstract：:We have previously shown that protein kinase Cε (PKCε) is involved in mitochondrial dysfunction in renal proximal tubular cells (RPTC). This study examined mitochondrial targets of active PKCε in RPTC injured by the model oxidant tert-butyl hydroperoxide (TBHP). TBHP exposure augmented the levels of phosphorylated (ac...

journal_title：Journal of cellular biochemistry

authors： Nowak G,Bakajsova-Takacsova D

更新日期：2018-11-01 00:00:00

abstract：:The hypothesis that intercellular adhesion can be subdivided into two separable phenomena, an initial recognition event and a subsequent stabilization, is supported by the use of a new cell binding assay that provides a quantitative measure of intercellular binding strengths. Radioactive single cells are brought into ...

journal_title：Journal of cellular biochemistry

authors： McClay DR,Marchase RB

更新日期：1982-01-01 00:00:00

abstract：:ZC3H12D belongs to a recently discovered family of proteins containing four members of which the most studied and best described is the RNase ZC3H12A (MCPIP1/Regnase-1). ZC3H12A is a crucial negative regulator of inflammation. It accelerates the turnover of transcripts of a spectrum of proinflammatory cytokines, as we...

journal_title：Journal of cellular biochemistry

authors： Wawro M,Kochan J,Krzanik S,Jura J,Kasza A

更新日期：2017-03-01 00:00:00

abstract：:The conversion of expandable liver progenitor cells into pancreatic beta cells would provide a renewable cell source for diabetes cell therapy. Previously, we reported the establishment of liver epithelial progenitor cells (LEPCs). In this work, LEPCs were modified into EGFP/Pdx-1 LEPCs, cells with stable expression o...

journal_title：Journal of cellular biochemistry

authors： Jin CX,Li WL,Xu F,Geng ZH,He ZY,Su J,Tao XR,Ding XY,Wang X,Hu YP

更新日期：2008-05-01 00:00:00

abstract：:We previously described a color-coded imaging model that can quantify the length of nascent blood vessels using Gelfoam® implanted in nestin-driven green fluorescent protein (ND-GFP) nude mice. In ND-GFP mice, nascent blood vessels are labeled with GFP. We report here that osteosarcoma cells promote angiogenesis in th...

journal_title：Journal of cellular biochemistry

authors： Uehara F,Tome Y,Miwa S,Hiroshima Y,Yano S,Yamamoto M,Mii S,Maehara H,Bouvet M,Kanaya F,Hoffman RM

更新日期：2014-09-01 00:00:00

abstract：:In vivo clearance studies have indicated that the clearance of proteinase complexes of the homologous serine proteinase inhibitors alpha 1-proteinase inhibitor and antithrombin III occurs via a specific and saturable pathway located on hepatocytes. In vitro hepatocyte-uptake studies with antithrombin III-proteinase co...

journal_title：Journal of cellular biochemistry

authors： Fuchs HE,Michalopoulos GK,Pizzo SV

更新日期：1984-01-01 00:00:00

abstract：:Craniosynostosis is a condition in which some or all of the sutures in the skull of an infant close prematurely. Fibroblast growth factor receptor 2 (FGFR2) mutations are a well-known cause of craniosynostosis. Many syndromes that comprise craniosynostosis, such as Apert syndrome, Crouzon syndrome, and Pfeiffer syndro...

journal_title：Journal of cellular biochemistry

authors： Park J,Park OJ,Yoon WJ,Kim HJ,Choi KY,Cho TJ,Ryoo HM

更新日期：2012-02-01 00:00:00

abstract：:The smallest rotary motor of living cells, F0F1-ATP synthase, couples proton flow-generated by the OXPHOS system-from the intermembrane space back to the matrix with the conversion of ADP to ATP. While all mutations affecting the multisubunit complexes of the OXPHOS system probably impact on the cell's output of ATP, ...

journal_title：Journal of cellular biochemistry

authors： Vazquez-Memije ME,Rizza T,Meschini MC,Nesti C,Santorelli FM,Carrozzo R

更新日期：2009-04-01 00:00:00

abstract：:Magnesium homeostasis in HL-60 promyelocytic leukemia cells was compared to that in neutrophyl-like HL-60 cells obtained by 1.3% DMSO treatment. Magnesium homeostasis was studied by the characterization of magnesium efflux, the identification of intracellular magnesium pools, and the regulation of intracellular ionize...

journal_title：Journal of cellular biochemistry

authors： Wolf FI,Covacci V,Bruzzese N,Di Francesco A,Sacchetti A,Corda D,Cittadini A

更新日期：1998-12-01 00:00:00

abstract：:We studied how deficiency in lamins A/C and lamina-associated polypeptide 2α (Lap2α) affects DNA repair after irradiation. A-type lamins and Lap2α were not recruited to local DNA lesions and did not accumulate to γ-irradiation-induced foci (IRIF), as it is generally observed for well-known marker of DNA lesions, 53BP1...

journal_title：Journal of cellular biochemistry

authors： Bártová E,Legartová S,Krejčí J,Řezníčková P,Kovaříková AS,Suchánková J,Fedr R,Smirnov E,Hornáček M,Raška I

更新日期：2018-11-01 00:00:00

abstract：:Fibroblasts play a major role in processes such as wound repair, scarring, and fibrosis. Differentiation into myofibroblasts, characterized by upregulation of smooth muscle alpha-actin (smalpha) in response to profibrotic agents such as TGFbeta is believed to be an important step in fibrosis. Therefore, elucidating me...

journal_title：Journal of cellular biochemistry

authors： Sousa AM,Liu T,Guevara O,Stevens J,Fanburg BL,Gaestel M,Toksoz D,Kayyali US

更新日期：2007-04-15 00:00:00

abstract：:To obtain sufficient numbers of cells for tissue engineering applications, human bone marrow-derived mesenchymal stem cells (hBM-MSC) are commonly cultured as monolayers in incubators containing room air. In this study, we investigated whether three-dimensional (3D) culture conditions and incubator gas concentrations ...

journal_title：Journal of cellular biochemistry

authors： Karlsen TA,Mirtaheri P,Shahdadfar A,Fløisand Y,Brinchmann JE

更新日期：2011-02-01 00:00:00

abstract：:The cellular basis of metastasis is poorly understood. An important step to understanding this process is to be able to visualize the routes by which cancer cells migrate from the primary tumor to various distant sites to eventually form metastasis. Our laboratory previously developed single-cell in vivo imaging using...

journal_title：Journal of cellular biochemistry

authors： Zhang Y,Wang X,Hoffman RM,Seki N

更新日期：2016-04-01 00:00:00

abstract：:Reactive oxygen species (ROS) produced by endothelial cells and macrophages play important roles in atherogenesis because they promote the formation of oxidized low-density lipoproteins (oxLDL). Extracellular-superoxide dismutase (EC-SOD) is mainly produced by vascular smooth muscle cells (VSMCs), is secreted into the...

journal_title：Journal of cellular biochemistry

authors： Makino J,Asai R,Hashimoto M,Kamiya T,Hara H,Ninomiya M,Koketsu M,Adachi T

更新日期：2016-11-01 00:00:00

abstract：:Amyloid precursor protein (APP) has been characterized as an adipocyte-secreted protein that might contribute to obesity-related insulin resistance, inflammation, and dementia. In the current study, regulation of APP by the proinflammatory and insulin resistance-inducing cytokine tumor necrosis factor (TNF) alpha was ...

journal_title：Journal of cellular biochemistry

authors： Sommer G,Kralisch S,Lipfert J,Weise S,Krause K,Jessnitzer B,Lössner U,Blüher M,Stumvoll M,Fasshauer M

更新日期：2009-12-15 00:00:00

abstract：:Pre-eclampsia (PE) is a pregnancy disease that causes maternal death and threatens the health of newborns. Accumulating evidence has revealed the essential roles of long noncoding RNAs (lncRNAs) in the progression of PE. The present investigation determined lncRNA ZEB2 antisense RNA 1 (ZEB2-AS1) expression in PE and l...

journal_title：Journal of cellular biochemistry

authors： Gao Y,Guo X,Li Y,Sha W,She R

更新日期：2019-10-01 00:00:00

abstract：:The activated c-Ha-rasVal12 oncogene is often involved in the genesis of human malignancies. We show here that in c-Ha-rasVal12 oncogene-transformed mouse NIH 3T3 fibroblasts the copy number and expression level of the mutant ras oncogene correlates with the degree of chromatin decondensation, as assessed by micrococc...

journal_title：Journal of cellular biochemistry

authors： Laitinen J,Sistonen L,Alitalo K,Hölttä E

更新日期：1995-01-01 00:00:00

abstract：:Long noncoding RNAs (lncRNAs) are vital mediators involved in cancer progression. Previous studies confirmed that FOXD2 adjacent opposite strand RNA 1 (FOXD2-AS1) is upregulated in tumor diseases. The potential influence of FOXD2-AS1 in glioma progression, however, remains unknown. In this paper, FOXD2-AS1 was found t...

journal_title：Journal of cellular biochemistry

authors： Wang J,Li B,Wang C,Luo Y,Zhao M,Chen P

更新日期：2019-12-01 00:00:00

abstract：:We are interested in understanding the molecular events associated with the growth-arrest of vascular SMCs. We constructed a subtracted cDNA library enriched in nucleotide sequences associated with quiescent SMCs. This library was screened with similarly subtracted 32P-labeled cDNAs to identify growth-arrest associate...

journal_title：Journal of cellular biochemistry

authors： Ge L,Liau G

更新日期：1995-02-01 00:00:00

abstract：:The HFE (HLA-H) gene is a strong candidate gene for hereditary haemochromatosis and was localized on the short arm of chromosome 6 to 6p21.3-p22. In addition, the sequence of the homologous mouse and rat cDNA and a partial sequence from the mouse gene have been reported recently. In this report, we describe the locati...

journal_title：Journal of cellular biochemistry

authors： Albig W,Drabent B,Burmester N,Bode C,Doenecke D

更新日期：1998-05-01 00:00:00

abstract：:4-hydroxynonenal (HNE), a lipid peroxidation end product, is produced abundantly in osteoarthritic (OA) articular tissues and was recently identified as a potent catabolic factor in OA cartilage. In this study, we provide additional evidence that HNE acts as an inflammatory mediator by elucidating the signaling cascad...

journal_title：Journal of cellular biochemistry

authors： Vaillancourt F,Morquette B,Shi Q,Fahmi H,Lavigne P,Di Battista JA,Fernandes JC,Benderdour M

更新日期：2007-04-01 00:00:00

abstract：:Adult human mesenchymal stem cells (MSCs) hold promise for an increasing list of therapeutic uses due to their ease of isolation, expansion, and multi-lineage differentiation potential. To maximize the clinical potential of MSCs, the underlying mechanisms by which MSC functionality is controlled must be understood. We...

journal_title：Journal of cellular biochemistry

authors： Pricola KL,Kuhn NZ,Haleem-Smith H,Song Y,Tuan RS

更新日期：2009-10-15 00:00:00

abstract：:The comet assay is one of the most widely used approaches for detecting DNA damage; generally, it provides information on the cell population-averaged level of DNA damage. Here, we present an automatic technique for easy measurement of standard comet characteristics and an annotation of the cell cycle phase of each co...

journal_title：Journal of cellular biochemistry

authors： Luzhin AV,Velichko AK,Razin SV,Kantidze OL

更新日期：2016-10-01 00:00:00

abstract：:The principal problem arising from prostate cancer (PCa) is its propensity to metastasize to bones, and it's crucial to understand the mechanism of tumor progression to metastasis in order to develop therapies that may reduce the morbidity and mortality of PCa patients. Although we had identified that microRNA(miR)-14...

journal_title：Journal of cellular biochemistry

authors： Guo W,Ren D,Chen X,Tu X,Huang S,Wang M,Song L,Zou X,Peng X

更新日期：2013-07-01 00:00:00

abstract：:Epilepsy is a brain and neurological disorder with high prevalence. It was reported that more than 70% of epileptic seizures were controlled by anti-epileptic medications, whereas the lack of evidence with respect to head-to-head comparisons motivated researchers to seek alternative approaches that are able to provide...

journal_title：Journal of cellular biochemistry

authors： Zhao T,Feng X,Liu J,Gao J,Zhou C

更新日期：2017-09-01 00:00:00

abstract：:Connexin43 (Cx43) forms gap junctions that mediate intercellular communication between osteoblasts. We have examined the effects of prostaglandin E2 (PGE2) and parathyroid hormone (PTH) on gap junctional communication in the rat osteogenic sarcoma cells UMR 106-01. Incubation with either PGE2 or PTH rapidly (within 30...

journal_title：Journal of cellular biochemistry

authors： Civitelli R,Ziambaras K,Warlow PM,Lecanda F,Nelson T,Harley J,Atal N,Beyer EC,Steinberg TH

更新日期：1998-01-01 00:00:00