Real Time Metastatic Route Tracking of Orthotopic PC-3-GFP Human Prostate Cancer Using Intravital Imaging.

abstract：:HSP90 chaperones are transducer proteins of many signaling pathways in cells. Using a highly specific inhibitor, geldanamycin (GA), an increasing number of the HSP90 client proteins have been identified. Nevertheless, there is little information on the differential transactivation of the two isoforms of the hsp90 gene...

journal_title：Journal of cellular biochemistry

authors： Chao CC,Sun FC,Wang CH,Lo CW,Chang YS,Chang KC,Chang MD,Lai YK

更新日期：2008-07-01 00:00:00

abstract：:CD38 is a type II transmembrane glycoprotein found mainly on the plasma membrane involved in the metabolism of cADPR and NAADP, two nucleotides with calcium mobilizing activity independent of inositol trisphosphate. Recent data report the presence of CD38 in different cellular compartments raising new questions about ...

journal_title：Journal of cellular biochemistry

authors： Trubiani O,Guarnieri S,Eleuterio E,Di Giuseppe F,Orciani M,Angelucci S,Di Primio R

更新日期：2008-03-01 00:00:00

abstract：:A homogeneous preparation of a urinary glycoprotein has been isolated from urine of patients with malignant melanoma and advanced adenocarcinomas of colon and lung. This molecule, Mr 30 kDa, is homologous to EDC1, a proteinase inhibitor antigenically related to plasma inter-alpha-trypsin inhibitor (IATI) originally is...

journal_title：Journal of cellular biochemistry

authors： Chawla RK,Lawson DH,Travis J

更新日期：1990-04-01 00:00:00

abstract：:Osterix belongs to the SP gene family and is a core transcription factor responsible for osteoblast differentiation and bone formation. Activation of protein kinase A (PKA), a serine/threonine kinase, is essential for controlling bone formation and BMP-induced osteoblast differentiation. However, the relationship betw...

journal_title：Journal of cellular biochemistry

authors： He S,Choi YH,Choi JK,Yeo CY,Chun C,Lee KY

更新日期：2014-10-01 00:00:00

abstract：:Insulin receptor was examined as a substrate for the multipotential protein kinase casein kinase I. Casein kinase I phosphorylated partially purified insulin receptor from human placenta as shown by immunoprecipitation of the complex with antiserum to the insulin receptor. Analysis of the phosphorylated complex by pol...

journal_title：Journal of cellular biochemistry

authors： Tuazon PT,Pang DT,Shafer JA,Traugh JA

更新日期：1985-01-01 00:00:00

abstract：:To study hematopoietic differentiation a variety of in vitro systems have been established using hematopoietic precursors derived from various explanted adult and fetal tissues. In this prospective we describe and discuss the potential of a novel system for studying the earliest stages of hematopoietic development. In...

journal_title：Journal of cellular biochemistry

authors： Snodgrass HR,Schmitt RM,Bruyns E

更新日期：1992-07-01 00:00:00

abstract：:Bone formation is under the control of a set of transcription factors. Ids are inhibitory helix-loop-helix (HLH) transcription factors and expression of Id genes in osteoblasts is under the control of calciotropic agents such as BMP and vitamin D. However, the function of Ids during bone formation in vivo has not yet ...

journal_title：Journal of cellular biochemistry

authors： Maeda Y,Tsuji K,Nifuji A,Noda M

更新日期：2004-10-01 00:00:00

abstract：:We report here that the antiestrogen tamoxifen (TAM) induces cell death in human breast cancer cell line MCF-7. We assessed the type of cell death induced by TAM in this breast cancer cell line on the basis of morphological and biochemical characteristics. Dying cells showed morphological characteristics of apoptosis,...

journal_title：Journal of cellular biochemistry

authors： Chen H,Tritton TR,Kenny N,Absher M,Chiu JF

更新日期：1996-04-01 00:00:00

abstract：:Endochondral bone formation is one of the most extensively examined developmental sequences within vertebrates. This process involves the coordinated temporal/spatial differentiation of three separate tissues (cartilage, bone, and the vasculature) into a variety of complex structures. The differentiation of chondrocyt...

journal_title：Journal of cellular biochemistry

authors： Gerstenfeld LC,Shapiro FD

更新日期：1996-07-01 00:00:00

abstract：:Prostaglandin E2 (PGE2) is one of pro-inflammatory mediators. PGE2 maintains the homeostasis of many organs including articular cartilage, and a previous report showed that continuous inhibition of PGE2 accelerates the progression of osteoarthritis (OA). While PGE2 inhibits matrix metalloprotease (MMP) expression in s...

journal_title：Journal of cellular biochemistry

authors： Nishitani K,Ito H,Hiramitsu T,Tsutsumi R,Tanida S,Kitaori T,Yoshitomi H,Kobayashi M,Nakamura T

更新日期：2010-02-01 00:00:00

abstract：:E-peptide of the pro-Insulin-like growth factor-I (pro-IGF-I) is produced from pre-pro-IGF-I by proteolytic cleavage in the post-translational processing. Previous in vitro studies conducted in our laboratory showed that Ea4-peptide of rainbow trout (rt) pro-IGF-I or Eb-peptide of human (h) pro-IGF-I exhibited activit...

journal_title：Journal of cellular biochemistry

authors： Chen MJ,Chiou PP,Lin P,Lin CM,Siri S,Peck K,Chen TT

更新日期：2007-08-01 00:00:00

abstract：:The initiation of DNA replication in T lymphocytes appears to be regulated by two distinct activities: one associated with proliferation which mediates initiation, and another associated with quiescence which blocks initiation. Activated lymphocytes and proliferating lymphoid cell lines produce an activity, termed ADR...

journal_title：Journal of cellular biochemistry

authors： Coffman FD,Fresa KL,Cohen S

更新日期：1991-01-01 00:00:00

abstract：:Serous ovarian cancer (SOC) is the most common form of the histological subtype of epithelial ovarian cancer, with the worst clinical outcome. Despite improvements in surgery and chemotherapy, most patients with SOC experience recurrence within 12-18 months of first-line treatment. Current studies are unable to robust...

journal_title：Journal of cellular biochemistry

authors： Deng K,Zhang F,Song W,Zhao W,Rong Z,Cai Y,Xu H,Lu M,Wang W,Li A,Hou Y,Li Z,Li K

更新日期：2018-11-01 00:00:00

abstract：:Periodontitis, a common chronic inflammatory disease of the periodontium, is caused by dental plaque formation induced by microorganisms. Recent studies have demonstrated that lncRNAs play a critical role in the regulation of gene expression and in the pathogenesis of diseases. To demonstrate that periodontitis is ass...

journal_title：Journal of cellular biochemistry

authors： Zou Y,Li C,Shu F,Tian Z,Xu W,Xu H,Tian H,Shi R,Mao X

更新日期：2015-04-01 00:00:00

abstract：:Circular RNAs (circRNAs) are a newly validated type of noncoding RNAs recently found to be deregulated in several human cancers. More accurate and specific noninvasive biomarkers are strongly needed for better diagnosis and prognosis of hepatocellular carcinoma (HCC). We performed a bioinformatics analysis to retrieve...

journal_title：Journal of cellular biochemistry

authors： Matboli M,Shafei AE,Ali MA,Ashry AM,Kamal KM,Agag MA,Reda I,Tash EF,Ali M

更新日期：2018-11-13 00:00:00

abstract：BACKGROUND:Acinetobacter baumannii has emerged as a major cause of nosocomial infections. Various resistance mechanisms of A. baumannii against antibiotics have transformed it into a successful nosocomial pathogen. Because of the limited number of available antibiotics, we used a medicinal plant with an antibacterial e...

journal_title：Journal of cellular biochemistry

authors： Hassannejad N,Bahador A,Rudbari NH,Modarressi MH,Parivar K

更新日期：2019-11-01 00:00:00

abstract：:The present study investigates the direct action of 5-methoxytryptophol (5-MTX) in both MC3T3-E1 and RAW264.7 cells and compares it with melatonin (MEL), another 5-methoxyindol known to play a significant role on bone metabolism. We first screened increasing doses of both 5-MTX and MEL to determine their effect on met...

journal_title：Journal of cellular biochemistry

authors： Satué M,Ramis JM,del Mar Arriero M,Monjo M

更新日期：2015-04-01 00:00:00

abstract：:Reveromycin A (RM-A), a small natural product isolated from Streptomyces bacteria, is a potential osteoporosis therapeutic in that it specifically induces apoptosis in osteoclasts but not osteoblasts. The purpose of the study presented here was to further elucidate the intracellular mechanisms of RM-A death effects in...

journal_title：Journal of cellular biochemistry

authors： Mead B,Morgan H,Mann-Knowlton A,Tedeschi L,Sloan C,Lang S,Hines C,Gragg M,Stofer J,Riemann K,Derr T,Heller E,Collins D,Landis P,Linna N,Jones D

更新日期：2015-08-01 00:00:00

abstract：:In the last 20 years, more than 1,500 gene therapy clinical trials have been approved worldwide targeting a variety of indications, from inherited monogenic diseases to acquired conditions such as cancer, cardiovascular and infectious diseases. However, concerns about the safety and efficacy of gene therapy pharmaceut...

journal_title：Journal of cellular biochemistry

authors： Coutu DL,Yousefi AM,Galipeau J

更新日期：2009-10-15 00:00:00

abstract：:Cellular differentiation is caused by highly controlled modifications in the gene expression but rarely involves a change in the DNA sequence itself. Histone acetylation is a major epigenetic factor that adds an acetyl group to histone proteins, thus altering their interaction with DNA and nuclear proteins. Illuminati...

journal_title：Journal of cellular biochemistry

authors： Tao H,Li Q,Lin Y,Zuo H,Cui Y,Chen S,Chen Z,Liu H

更新日期：2020-03-01 00:00:00

abstract：:Procollagen (Type I) contains a noncollagenous COOH-terminal propeptide (C-propeptide) hypothesized to be important in directing chain association and alignment during assembly. We previously expressed human pro-alpha2(I) cDNA in rat liver epithelial cells, W8, that produce only pro-alpha1(I) trimer collagen (Lim et a...

journal_title：Journal of cellular biochemistry

authors： Lim AL,Doyle SA,Balian G,Smith BD

更新日期：1998-11-01 00:00:00

abstract：:The bcl-2 gene has a unique function among mammalian oncogenes as a negative regulator of apoptosis. Its expression pattern in embryonic and adult tissues is consistent with a role in maintaining in vivo survival of specific cell types. The biochemical function of bcl-2 is unknown, but its localization to mitochondria...

journal_title：Journal of cellular biochemistry

authors： Park JR,Hockenbery DM

更新日期：1996-01-01 00:00:00

abstract：:Metastatic cancer is a complex positive feedback loop system. Such as system has a tendency to acquire extreme robustness. Signaling pathways controlling that robustness can fail completely if an essential element from the signaling is removed. That element is a locus of fragility. Targeting that locus represents the ...

journal_title：Journal of cellular biochemistry

authors： Radisavljevic Z

更新日期：2008-08-15 00:00:00

abstract：:The SON protein is a ubiquitously expressed DNA- and RNA-binding protein primarily localized to nuclear speckles. Although several early studies implicated SON in DNA-binding, tumorigenesis and apoptosis, functional significance of this protein had not been recognized until recent studies discovered SON as a novel RNA...

journal_title：Journal of cellular biochemistry

authors： Hickey CJ,Kim JH,Ahn EY

更新日期：2014-02-01 00:00:00

abstract：:The three ingredients for the successful tissue engineering of bone and cartilage are regulatory signals, cells, and extracellular matrix. Recent advances in cellular and molecular biology of the growth and differentiation factors have set the stage for a symbiosis of biotechnology and biomaterials. Recent advances pe...

journal_title：Journal of cellular biochemistry

authors： Reddi AH

更新日期：1994-10-01 00:00:00

abstract：:Genistein, a natural isoflavone phytoestrogen present in soybeans, caused a dose-dependent growth inhibition of the two hormone-sensitive cell lines T47D and ZR75.1 and of the two hormone-independent cell lines MDAMB-231 and BT20. Flow cytometric analysis of cells treated for 4 days with 15 and 30 microM genistein sho...

journal_title：Journal of cellular biochemistry

authors： Cappelletti V,Fioravanti L,Miodini P,Di Fronzo G

更新日期：2000-09-14 00:00:00

abstract：OBJECTIVE:To investigate the correlation between serum protein level of insulin growth factor 1 (IGF-1) and the degree of liver fibrosis in patients with chronic hepatitis C (CHC) combined with type 2 diabetes mellitus (T2DM). METHODS:The cases are divided into four groups. Then serum levels of IFG-1, alanine aminotra...

journal_title：Journal of cellular biochemistry

authors： Cao LH,Lu FM,Lu XJ,Zhu LY

更新日期：2018-11-01 00:00:00

abstract：:A variant human H2B histone gene (GL105), previously shown to encode a 2300 nt replication independent mRNA, has been cloned. We demonstrate this gene expresses alternative mRNAs regulated differentially during the HeLa S3 cell cycle. The H2B-Gl105 gene encodes both a 500 nt cell cycle dependent mRNA and a 2300 nt con...

journal_title：Journal of cellular biochemistry

authors： Collart D,Romain PL,Huebner K,Pockwinse S,Pilapil S,Cannizzaro LA,Lian JB,Croce CM,Stein JL,Stein GS

更新日期：1992-12-01 00:00:00

abstract：:Embryo development block seriously limits the success of in vitro embryo production and assisted reproductive technology. Although numerous researchers have explored this problem, it remains to be solved. In this study, we found that melatonin supplementation at 10-8 and 10-9 M in M16 significantly reduced two-cell bl...

journal_title：Journal of cellular biochemistry

authors： Shi F,Li H,Wang E,Chen ZJ,Zhang C

更新日期：2018-11-01 00:00:00

abstract：:The cholesterol hydroxylase/lyase (CHL) system, consisting of cytochrome P450scc, adrenodoxin (Adx) and adrenodoxin reductase (AdR), initiates mammalian steroidogenesis, converting cholesterol to pregnenolone. The foot-and-mouth disease virus 2A-based method allows to express multiple proteins from a single transcript...

journal_title：Journal of cellular biochemistry

authors： Efimova VS,Isaeva LV,Labudina AA,Tashlitsky VN,Rubtsov MA,Novikova LA

更新日期：2019-03-01 00:00:00