Effects of vitamin D3 on signaling by prostaglandin E2 in osteoblast-like cells.

abstract：:The contribution of proximal tubules (PT) to albumin uptake is now well recognized, however, its regulation is understudied area. There are reports suggesting that insulin resistance is associated with the development of albuminuria in nondiabetic individuals. We have previously reported reduced insulin receptor (IR) ...

journal_title：Journal of cellular biochemistry

authors： Kumari M,Sharma R,Pandey G,Ecelbarger CM,Mishra P,Tiwari S

更新日期：2019-06-01 00:00:00

abstract：:Numerous studies have demonstrated the role of A3 adenosine receptor (A3AR) and signaling pathways in the multiple aspects of the tumor. However, there is a little study about the function of A3AR in the biological processes of cancer stem cells (CSCs). CSCs have a critical role in the maintenance and survival of brea...

journal_title：Journal of cellular biochemistry

authors： Jafari SM,Panjehpour M,Aghaei M,Joshaghani HR,Enderami SE

更新日期：2017-09-01 00:00:00

abstract：:Thrombin has been shown to play a key role in lung diseases such as pulmonary fibrosis via the induction of fibrotic cytokine- chemokine (CC motif) ligand-2 (CCL2) expression. We previously reported that transcription factor nuclear factor-κB (NF-κB) is responsible for thrombin-induced CCL2 expression in human lung fi...

journal_title：Journal of cellular biochemistry

authors： Deng X,Zhou X,Deng Y,Liu F,Feng X,Yin Q,Gu Y,Shi S,Xu M

更新日期：2017-11-01 00:00:00

abstract：:Interleukin-15 (IL-15), a cytokine secreted by several cell types, has important physiological roles in the activity, proliferation, and viability of immune cells. It has both chemoattractant and proinflammatory properties, and may promote bone destruction. A previous study has shown that IL-15 alone exerts no effect ...

journal_title：Journal of cellular biochemistry

authors： Okabe I,Kikuchi T,Mogi M,Takeda H,Aino M,Kamiya Y,Fujimura T,Goto H,Okada K,Hasegawa Y,Noguchi T,Mitani A

更新日期：2017-04-01 00:00:00

abstract：:Preeclampsia is a pathologic complication of pregnancy, associated with increased apoptosis in the cytotrophoblasts as the main cause of this disorder. Caspase-3 is a key apoptosis-related enzyme that both mitochondrial and death receptor apoptotic pathways can activate. In this study, we aimed to investigate the effe...

journal_title：Journal of cellular biochemistry

authors： Teimoori B,Yazdi A,Rezaei M,Mohammadpour-Gharehbagh A,Jahantigh D,Salimi S

更新日期：2018-08-01 00:00:00

abstract：:Published data indicate that the protease-activated receptor (PAR) 2 is involved in the pathogenesis of some cardiovascular diseases; the underlying mechanism is to be further investigated. Ve-cadherin is a critical molecule in maintaining the endothelial barrier integrity. This study aims to investigate the role of P...

journal_title：Journal of cellular biochemistry

authors： Zhang R,Ge J

更新日期：2017-12-01 00:00:00

abstract：:Circular RNA (circRNA) is a new noncoding RNAs and plays an important role in many pathological processes. Recently, studies have shown that circular RNA_PRKCI (circ-PRKCI) regulates cell proliferation and cell migration of tumor cells. Esophageal carcinoma is a highly malignant digestive tract tumor, which is divided...

journal_title：Journal of cellular biochemistry

authors： Shi N,Shan B,Gu B,Song Y,Chu H,Qian L

更新日期：2019-06-01 00:00:00

abstract：:In women, calcium excretion in the urine rises after menopause and falls with estrogen replacement therapy. The amount of calcium lost in the urine following estrogen therapy is less than should occur based on changes in serum calcium and the amount of calcium filtered by the kidney. This suggests there may be a direc...

journal_title：Journal of cellular biochemistry

authors： Criddle RA,Zheng MH,Dick IM,Callus B,Prince RL

更新日期：1997-06-01 00:00:00

abstract：:Pyrazinamide is an essential first-line antitubercular drug which plays pivotal role in tuberculosis treatment. It is a prodrug that requires amide hydrolysis by mycobacterial pyrazinamidase enzyme for conversion into pyrazinoic acid (POA). POA is known to target ribosomal protein S1 (RpsA), aspartate decarboxylase (P...

journal_title：Journal of cellular biochemistry

authors： Singh A,Somvanshi P,Grover A

更新日期：2018-11-02 00:00:00

abstract：:Using computer stress-induced duplex destabilization (SIDD) analysis and binding experiments, we identified a S/MAR element (-599/-200 bp) (Hp-S/MAR) adjacent to the cis-element (-165/-56 bp) in the rat haptoglobin gene. We examined its functional interactions with the lamins and lamin-associated proteins in the basal...

journal_title：Journal of cellular biochemistry

authors： Vidaković M,Dinić S,Grdović N,Mihailović M,Uskoković A,Quesada P,Poznanović G

更新日期：2009-08-15 00:00:00

abstract：:In the present study, monoclonal antibodies were produced using porcine adipocyte extracts as the immunogen. Two of the monoclonal antibodies, designated CB6 and IB4, exhibited reactivity toward only cells containing lipid in stromal-vascular cell cultures. The antigens recognized by the CB6 and IB4 monoclonal antibod...

journal_title：Journal of cellular biochemistry

authors： Wright JT,Hausman GJ

更新日期：1991-03-01 00:00:00

abstract：:This study aims to investigate the combined effects of Pulsed wave low-level laser therapy (PW LLLT) and human bone marrow mesenchymal stem cell-conditioned medium (hBM-MSC-CM) on the microbial flora and tensiometrical properties of an infected wound model with methicillin-resistant staphylococcal aureus (MRSA) in an ...

journal_title：Journal of cellular biochemistry

authors： Kouhkheil R,Fridoni M,Piryaei A,Taheri S,Chirani AS,Anarkooli IJ,Nejatbakhsh R,Shafikhani S,Schuger LA,Reddy VB,Ghoreishi SK,Jalalifirouzkouhi R,Chien S,Bayat M

更新日期：2018-07-01 00:00:00

abstract：:Cumulating evidence has led to the idea that nuclear functions such as DNA replication, RNA transcription, RNA splicing and nucleocytoplasmic transport are facilitated by a proteinaceous architectural framework within the nuclear compartment and at the nuclear envelope. In the present study, we have used immunofluores...

journal_title：Journal of cellular biochemistry

authors： Haddad N,Paulin-Levasseur M

更新日期：2008-12-15 00:00:00

abstract：:Photodynamic therapy (PDT) employing methyl δ-aminolevulinic acid (Me-ALA), as a precursor of the photosensitizer protoporphyrin IX (PpIX), is used for the treatment of non melanoma cutaneous cancer (NMCC). However, one of the problems of PDT is the apparition of resistant cell populations. The aim of this study was t...

journal_title：Journal of cellular biochemistry

authors： Milla LN,Cogno IS,Rodríguez ME,Sanz-Rodríguez F,Zamarrón A,Gilaberte Y,Carrasco E,Rivarola VA,Juarranz A

更新日期：2011-09-01 00:00:00

abstract：:Several molecules extracted from natural products exhibit different biological activities, such as ion channel modulation, activation of signaling pathways, and anti-inflammatory or antitumor activity. In this study, we tested the antitumor ability of natural compounds extracted from the Raputia praetermissa plant. Am...

journal_title：Journal of cellular biochemistry

authors： Vital WD,Torquato HFV,Jesus LOP,Judice WAS,Silva MFDGFD,Rodrigues T,Justo GZ,Veiga TAM,Paredes-Gamero EJ

更新日期：2019-06-01 00:00:00

abstract：:Complete resection of malignant glioblastomas is usually impossible because of diffuse and widespread invasion of tumor cells, and complementary approaches need to be developed in order to improve the efficacy of current treatments. Consumption of fruits and berries has been associated with decreased risk of developin...

journal_title：Journal of cellular biochemistry

authors： Lamy S,Lafleur R,Bédard V,Moghrabi A,Barrette S,Gingras D,Béliveau R

更新日期：2007-01-01 00:00:00

abstract：:Loss of sensitivity to the negative growth regulator transforming growth factor beta (TGF beta) is a feature of many different tumor types and is likely involved in tumor progression. In some cases this loss of sensitivity to TGF beta has been shown to be manifest in the absence of membrane-associated TGF beta recepto...

journal_title：Journal of cellular biochemistry

authors： Alexandrow MG,Moses HL

更新日期：1997-09-15 00:00:00

abstract：BACKGROUND/AIMS:Fibroblast growth factor 21 (FGF21) plays a protective role in ischemia/reperfusion induced cardiac injury. However, the exact molecular mechanism of FGF21 action remains unclear. This study was designed the protective effect of FGF21 on the heart and its mechanism. METHOD:Adenovirus vector expressing ...

journal_title：Journal of cellular biochemistry

authors： Sun M,Jin L,Bai Y,Wang L,Zhao S,Ma C,Ma D

更新日期：2019-12-01 00:00:00

abstract：:The transcription factors of the nuclear hormone receptor family regulate gene expression via a complex network of macromolecular interactions. The ligand dependent activity of the vitamin D receptor is of particular interest because it modulates gene expression by the heterodimeric interaction with retinoid X recepto...

journal_title：Journal of cellular biochemistry

authors： Berghöfer-Hochheimer Y,Zurek C,Langer G,Munder T

更新日期：1997-08-01 00:00:00

abstract：:Our laboratory pioneered patient-derived orthotopic xenograft (PDOX) mouse models using surgical orthotopic implantation (SOI). PDOX models are patient-like, in contrast to the ectopic subcutaneous-transplant cancer models. In the present study, we demonstrate that an undifferentiated pleomorphic soft-tissue sarcoma (...

journal_title：Journal of cellular biochemistry

authors： Kiyuna T,Murakami T,Tome Y,Igarashi K,Kawaguchi K,Russell T,Eckardt MA,Crompton J,Singh A,Bernthal N,Bukata S,Federman N,Kanaya F,Eilber FC,Hoffman RM

更新日期：2017-02-01 00:00:00

abstract：:The above article, published online on April 18, 2011 in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the journal Editor in Chief, Gary S. Stein, and Wiley Periodicals, Inc. The retraction has been agreed following an investigation from Wayne State University involving the sec...

journal_title：Journal of cellular biochemistry

authors：

更新日期：2016-08-01 00:00:00

abstract：:Thrombin is a potent mitogen for human vascular smooth muscle cells (HVSMC) and its enzymatic activity is required for this function. The present study demonstrates that prothrombin is also mitogenic for HVSMC due to the generation of enzymatically active thrombin which occurs upon incubation of prothrombin with the c...

journal_title：Journal of cellular biochemistry

authors： Benzakour O,Kanthou C,Lupu F,Dennehy U,Goodwin C,Scully MF,Kakkar VV,Cooper DN

更新日期：1995-12-01 00:00:00

abstract：:Lung cancer (LC) is the second common cancer for both women and men all over the world. Unfortunately, the number of LC deaths is increasing rapidly each year so early diagnosis of LC can be lifesaving. MicroRNAs are involved in multiple processes, such as cell differentiation, transcription, inflammation, proliferati...

journal_title：Journal of cellular biochemistry

authors： Asghariazar V,Sakhinia E,Mansoori B,Mohammadi A,Baradaran B

更新日期：2019-12-01 00:00:00

abstract：:The mass and function of bones depend on the maintenance of a complicated balance between osteoclast-mediated bone resorption and osteoblast-mediated bone formation. An inhibitor of osteoclast differentiation and/or function is expected to be useful for treatment of bone lytic diseases such as osteoporosis, rheumatoid...

journal_title：Journal of cellular biochemistry

authors： Yonezawa T,Mase N,Sasaki H,Teruya T,Hasegawa S,Cha BY,Yagasaki K,Suenaga K,Nagai K,Woo JT

更新日期：2012-02-01 00:00:00

abstract：:p38 mitogen-activated protein kinase (MAPK) is of fundamental importance in a cell's response to environmental stresses, cytokines and DNA damage. p38 resides in the cytoplasm of resting cells, and translocates into the nucleus upon activation, yet the exact mechanisms remain largely unclear. We show here that the pho...

journal_title：Journal of cellular biochemistry

authors： Gong X,Ming X,Deng P,Jiang Y

更新日期：2010-08-15 00:00:00

abstract：:The myelin basic protein (MBP)-phosphorylating enzymes present during maturation and early embryogenesis of the sea star (Pisaster ochraceus) were investigated. The major maturation-activated MBP kinase (p45 Mapk) was molecularly cloned based on tryptic sequence information obtained with the purified enzyme and shown ...

journal_title：Journal of cellular biochemistry

authors： Lefebvre DL,Charest DL,Yee A,Crawford BJ,Pelech SL

更新日期：1999-11-01 00:00:00

abstract：:Previous studies demonstrated that, upon attaining confluence, a clone of the renal epithelial cell, LLC-PK1, expressed progressively binding sites for the lectin Dolichos biflorus agglutinin (DBA) at the apical cell surface. Activation of cAMP-dependent protein kinase enhanced surface expression dramatically. The goa...

journal_title：Journal of cellular biochemistry

authors： Amsler K

更新日期：1993-08-01 00:00:00

abstract：:The aim of the present study was to test the hypothesis that the decreased renal tubular reabsorption of calcium observed in estrogen deficiency is associated with a local regulation of either PTHrP or PTH/PTHrP receptor genes in the kidney. Rats were randomly sham-operated (S) or ovariectomized receiving either vehic...

journal_title：Journal of cellular biochemistry

authors： Cros M,Silve C,Graulet AM,Morieux C,Ureña P,de Vernejoul MC,Bouizar Z

更新日期：1998-07-01 00:00:00

abstract：:Adipose tissue is critical in obesity and type II diabetes. Blocking of adipocyte differentiation is one of the anti-obesity strategies targeting on strong rise in fat storage and secretion of adipokine(s). However, the molecular basis of adipocyte differentiation and its regulation remains obscure. Therefore, we expo...

journal_title：Journal of cellular biochemistry

authors： Ye F,Zhang H,Yang YX,Hu HD,Sze SK,Meng W,Qian J,Ren H,Yang BL,Luo MY,Wu X,Zhu W,Cai WJ,Tong JB

更新日期：2011-10-01 00:00:00

abstract：:The activity of α-type cytosolic phospholipase A2 (cPLA2 α, group IVA PLA2 ), which releases arachidonic acid (AA), is mainly regulated by the Ca2+ -induced intracellular translocation/attachment of the enzyme to substrate membranes and its phosphorylation. We previously reported that tumor necrosis factor-α (TNFα) st...

journal_title：Journal of cellular biochemistry

authors： Nakamura H,Moriyama Y,Watanabe K,Tomizawa S,Yamazaki R,Takahashi H,Murayama T

更新日期：2017-12-01 00:00:00