Modulation of plasma glucose by the medial preoptic area in freely moving rats.

Abstract:

:The effect of norepinephrine (NE) injection into the medial preoptic area (MPOA) on plasma glucose was studied in freely moving male rats. The rats were implanted with chronic jugular catheters for blood sampling and with unilateral intracerebral cannulas placed just above the MPOA. Blood samples were taken immediately before and 5, 10, 15, and 30 min after NE injection. As early as 5 min after NE injection, plasma glucose levels rose rapidly, reaching a peak at 15 min poststimulus. The hyperglycemic response to NE injection into the MPOA was dose-related within the range of doses tested (10, 20, and 40 nmol). Previous administration of phentolamine (50 nmol), but not propranolol (100 nmol), into the MPOA blocked the hyperglycemic response to NE injection into the MPOA. The increase of plasma glucose induced by NE into the MPOA and the blockade of the hyperglycemic response to NE by phentolamine suggest the involvement of an alpha-adrenergic mechanism in MPOA-mediated hyperglycemia. On the basis of these and previous results, we propose that MPOA alpha-adrenergic synapses relay impulses activating the sympathetic outflow expressed by neurally mediated hyperglycemia.

journal_name

Physiol Behav

journal_title

Physiology & behavior

authors

De Castro MG,Foscolo RB,Reis AM,Coimbra CC

doi

10.1016/s0031-9384(96)00362-9

subject

Has Abstract

pub_date

1997-02-01 00:00:00

pages

215-20

issue

2

eissn

0031-9384

issn

1873-507X

pii

S0031938496003629

journal_volume

61

pub_type

杂志文章
  • High affinity binding of the calcium channel blocker, (+)-[methyl-3H]PN200-110(3HPN) in rat brain.

    abstract::PN200-110 is a recently introduced 1,4-dihydropyridine which has been demonstrated to be a potent calcium channel blocker. 3HPN has been shown to bind in a specific saturable manner to P2 fractions obtained from brain homogenates from male Sprague-Dawley rats. 3HPN binding was found to be temperature-dependent. Specif...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(89)90330-2

    authors: Magill SB,Stone JS,Parmar SS

    更新日期:1989-07-01 00:00:00

  • Sex differences in the effects of cocaine abuse across the life span.

    abstract::Cocaine alters brain function from the early days of development throughout the entire life of an individual. Since the first preclinical research on cocaine sensitization was published, sex differences in response to the drug in adult rats have been noted. With the appearance of reports on "crack babies" during the 1...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2009.12.017

    authors: Dow-Edwards D

    更新日期:2010-06-01 00:00:00

  • Androgen receptors in Purkinje neurons are modulated by systemic testosterone and sexual training in a region-specific manner in the male rat.

    abstract::The androgen receptor (AR) is a widely distributed molecule indicating the spread actions of its ligand steroid, and plays an important role underlying male sexual behavior. Nevertheless, the influence of steroid hormones and their receptors on cerebellar neurons, as foundation of sexual behavior, is largely unknown. ...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2016.01.027

    authors: Perez-Pouchoulen M,Toledo R,Garcia LI,Perez-Estudillo CA,Coria-Avila GA,Hernandez ME,Carrillo P,Manzo J

    更新日期:2016-03-15 00:00:00

  • Differential activation of chemically identified neurons in the caudal nucleus of the solitary tract in non-entrained rats after intake of satiating vs. non-satiating meals.

    abstract::Satiety signals arising from the gastrointestinal (GI) tract and related digestive organs during food ingestion and digestion are conveyed by vagal sensory afferents to the hindbrain nucleus of the solitary tract (NST). Two intermingled but chemically distinct NST neuronal populations have been implicated in meal size...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2014.01.015

    authors: Kreisler AD,Davis EA,Rinaman L

    更新日期:2014-09-01 00:00:00

  • Reliability and validity of computer scoring of behavioral sleep-wake states in rats and rabbits.

    abstract::Previous studies in human infants, rabbits, and rats have shown that states of sleep and wakefulness can be reliably identified from motility signals produced by respiration and body movement. Thoman has described a computer-scoring algorithm for automated scoring of behavioral states from motility signals in human in...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(93)90110-2

    authors: Carroll DA,Denenberg VH,Thoman EB

    更新日期:1993-08-01 00:00:00

  • Effects of ethanol in an open field apparatus: modification by U50488H and WIN 44441-3.

    abstract::The effects of U50488H, a kappa agonist, and WIN 44441-3, a kappa antagonist, and their modification of the effects of ethanol, on the behavior of rats in a modified open field apparatus, was examined. Crossover activity was increased by U50488H. Headpoke activity was decreased by WIN 44441-3 and increased by U50488H....

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(89)90129-7

    authors: Pohorecky LA,Patel V,Roberts P

    更新日期:1989-02-01 00:00:00

  • Consolidation and expression of a shock-induced odor preference in rat pups is facilitated by opioids.

    abstract::To support nipple attachment and huddling, rat pups must learn to approach and prefer maternal odor. Similar to other altricial species, rat pups have a sensitive period for learning this odor preference, which ends around postnatal day (PN) 10 and coincides with the emergence of walking. One characteristic of this se...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/s0031-9384(02)00961-7

    authors: Roth TL,Sullivan RM

    更新日期:2003-01-01 00:00:00

  • Unmasking of alpha1 adrenoceptor induced hypnogenic response from medial preoptic area.

    abstract::Earlier studies had indicated the possibility of the involvement of the alpha(1) adrenergic receptors on the medial preoptic (mPOA) neurons in hypnogenesis. Microinjection of alpha1 agonist methoxamine (0.05 microg) into the mPOA of the rats, maintained at an ambient temperature (Tamb) of 24 degrees C, did not produce...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2005.02.013

    authors: Vetrivelan R,Mallick HN,Kumar VM

    更新日期:2005-03-31 00:00:00

  • Hormonal reactions to fighting in rat colonies: prolactin rises during defence, not during offence.

    abstract::Male Wistar rats living in colonies of 4 males plus 4 females were compared to noncolony males, cohabitating with a female. Irreversible dominance relationships developed between one dominant male (D) and three subordinates (S). Dominants developed high basal testosterone levels and large preputial glands. Subordinate...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(92)90078-g

    authors: Dijkstra H,Tilders FJ,Hiehle MA,Smelik PG

    更新日期:1992-05-01 00:00:00

  • Flavor-nutrient learning is less rapid with fat than with carbohydrate in rats.

    abstract::Flavor-nutrient learning occurs when the post-ingestive consequences of a food are associated with its flavor. As a signal of the food's energy density, flavor-nutrient associations have the potential to contribute to the regulation of meal size. While all calorie sources (fat, carbohydrate, protein, ethanol) can supp...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2009.03.007

    authors: Revelle CH,Warwick ZS

    更新日期:2009-06-22 00:00:00

  • Effects of aerobic training, resistance training, or both on brain-derived neurotrophic factor in adolescents with obesity: The hearty randomized controlled trial.

    abstract::Brain derived neurotrophic factor (BDNF) is a protein that plays a critical role in modulating cognition in animals and humans. Aerobic exercise often increases BDNF in adults, but effects of this exercise modality and others among adolescents remain uncertain. This study examined the effects of aerobic training, resi...

    journal_title:Physiology & behavior

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.physbeh.2018.04.026

    authors: Goldfield GS,Kenny GP,Prud'homme D,Holcik M,Alberga AS,Fahnestock M,Cameron JD,Doucette S,Hadjiyannakis S,Tulloch H,Tremblay MS,Walsh J,Guerin E,Gunnell KE,D'Angiulli A,Sigal RJ

    更新日期:2018-07-01 00:00:00

  • Food intake in the domestic fowl: effect of intrahepatic lipid and amino acid infusions.

    abstract::Five experiments were conducted to determine the effect of hepatic and jugular infusions of amino acid and lipid solutions on short-term food intake of cockerels. Neither jugular nor hepatic infusions of amino acids had any effect on food intake of Single-Comb White Leghorn (SCWL) cockerels. Lipid infusions had no eff...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(86)90327-6

    authors: Lacy MP,Van Krey HP,Skewes PA,Denbow DM

    更新日期:1986-01-01 00:00:00

  • Involvement of the anterodorsal thalami nuclei on the hypophysoadrenal response to chronic stress in rats.

    abstract::Anterodorsal thalami nuclei (ADTN) exert an inhibitory influence on the hypophysoadrenal system (HAS) under basal and acute stress conditions; however, after chronic stress, the effect is different. The response to chronic immobilization stress (IMO) (forced immobilization for 15 min/day for 12 days) and variable chro...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/s0031-9384(98)00028-6

    authors: Suárez M,Maglianesi MA,Perassi NI

    更新日期:1998-04-01 00:00:00

  • Modification of the gerbil's taste behavior by the sucrose taste antagonist p-nitrophenyl alpha-D-glucopyranoside.

    abstract::Since the gerbil's chorda tympani nerve response to sucrose is antagonized by p-nitrophenyl alpha-D-glucopyransoide (PNP-Glu), the present taste aversion behavioral experiments sought to determine whether the gerbil's behavioral gustatory responses could be modified by adding PNP-Glu to taste solutions. Results demons...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(89)90033-4

    authors: Myers CE,Neita A,Jakinovich W Jr

    更新日期:1989-09-01 00:00:00

  • Mild exercise in female subjects impairs complex learning independent of hydration status and emotion.

    abstract:INTRODUCTION:Depending on type, intensity and duration, exercise can have both beneficial and detrimental effects on cognitive function. The impact of exercise on learning and memory is also sensitive to hydration status, so we hypothesized that mild hypohydration induced with exercise, will adversely impact executive ...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2017.08.013

    authors: Turner JM,Marsteller DA,Luxkaranayagam AT,Fletcher JM,Stachenfeld NS

    更新日期:2017-10-15 00:00:00

  • Wrist motion rhythm phase shifts in travelers may differ from changes in time zones.

    abstract::Wrist motions (223-471)/5 min were measured during 17-32 days of continuous recordings made from human passengers as they traveled across zero to five time zones for business and pleasure. The travelers all exhibited daily cycles of activity and rest. The duration of daily activity, alpha, was 1.1 h less at the destin...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(94)90088-4

    authors: Binkley S

    更新日期:1994-05-01 00:00:00

  • Angiotensin converting enzyme inhibition lowers body weight and improves glucose tolerance in C57BL/6J mice maintained on a high fat diet.

    abstract::The renin-angiotensin system (RAS) is functional within adipose tissue and angiotensin II, the active component of RAS, has been implicated in adipose tissue hypertrophy and insulin resistance. In this study, captopril, an angiotensin converting enzyme (ACE) inhibitor that prevents angiotensin II formation, was used t...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2009.05.009

    authors: Weisinger RS,Stanley TK,Begg DP,Weisinger HS,Spark KJ,Jois M

    更新日期:2009-08-04 00:00:00

  • Paternal responsiveness is associated with, but not mediated by reduced neophobia in male California mice (Peromyscus californicus).

    abstract::Hormones associated with pregnancy and parturition have been implicated in facilitating the onset of maternal behavior via reductions in neophobia, anxiety, and stress responsiveness. To determine whether the onset of paternal behavior has similar associations in biparental male California mice (Peromyscus californicu...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2012.05.012

    authors: Chauke M,de Jong TR,Garland T Jr,Saltzman W

    更新日期:2012-08-20 00:00:00

  • Repeated gastric distension alters food intake and neuroendocrine profiles in rats.

    abstract::The consumption of a large food bolus leads to stomach distension. Gastric distension potently signals the termination of a meal by stimulating gastric mechanoreceptors and activating neuroendocrine circuitry. The ability to terminate a meal is altered in disorders such as bulimia nervosa (BN), binge-eating disorder (...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2011.11.006

    authors: Hargrave SL,Kinzig KP

    更新日期:2012-02-28 00:00:00

  • Learning from spiny lobsters about chemosensory coding of mixtures.

    abstract::Studies of the peripheral olfactory system of the Caribbean spiny lobster Panulirus argus and related decapod crustaceans have helped us understand mechanisms of coding of mixtures, some of which are discussed in this review. Although the number of cells in the lobster's olfactory system is much lower than in vertebra...

    journal_title:Physiology & behavior

    pub_type: 杂志文章,评审

    doi:10.1016/s0031-9384(00)00202-x

    authors: Derby CD

    更新日期:2000-04-01 00:00:00

  • Vasopressin administration modulates anxiety-related behavior in rats.

    abstract::Experiments were performed to measure the influence of centrally and peripherally applied arginine vasopressin (AVP) on anxiety-related behavior as indicated by the elevated plus maze test. Central administration was performed into the septum using a microdialysis technique. In initial experiments, the microdialysis p...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/s0031-9384(98)00119-x

    authors: Appenrodt E,Schnabel R,Schwarzberg H

    更新日期:1998-06-15 00:00:00

  • A comparative study of the effect of starvation regimes on the foraging behavior of Portunus trituberculatus and Charybdis japonica.

    abstract::Predation of manila clams (Ruditapes philippinarum) by swimming crabs (Portunus trituberculatus) and Japanese stone crabs (Charybdis japonica) was compared in the laboratory under different starvation regimes by a video recording analysis system, and the mechanism of foraging behavior differences between them combined...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2015.07.011

    authors: Sun Y,Wang F,Dong S

    更新日期:2015-11-01 00:00:00

  • Intragastric infusion of denatonium conditions flavor aversions and delays gastric emptying in rodents.

    abstract::Because most naturally occurring toxins taste bitter to humans, any mechanism that reduces the rate at which bitter substances are ingested and digested should be adaptive. Based on the recent discovery of T2R bitter taste receptors in the gastrointestinal tract of rodents, we asked whether intragastric (IG) infusion ...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2007.11.029

    authors: Glendinning JI,Yiin YM,Ackroff K,Sclafani A

    更新日期:2008-03-18 00:00:00

  • Effect of a cage divider permitting social stimuli on stress and food intake in rats.

    abstract::The need to obtain data from individual laboratory animals has forced many researchers to singly-house small animals. This is costly to the researcher and isolation can adversely affect animal physiology and behavior which in turn may threaten the validity and generalization of experiment results to humans. We assesse...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2008.04.025

    authors: Boggiano MM,Cavigelli SA,Dorsey JR,Kelley CE,Ragan CM,Chandler-Laney PC

    更新日期:2008-09-03 00:00:00

  • Two novel paradigms for the simultaneous assessment of conditioned taste aversion and food intake effects of anorexic agents.

    abstract::The conditioned taste aversion (CTA) is routinely used to assess the aversive consequences of anorexic agents, including potential pharmacological therapies for obesity. In a typical CTA paradigm, rats briefly sampling a novel tastant (e.g., saccharin) are acutely administered with toxin (e.g., lithium chloride, LiCl)...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/s0031-9384(03)00189-6

    authors: Benoit SC,Air EL,Wilmer K,Messerschmidt P,Hodge KM,Jones MB,Eckstein DM,McOsker CC,Seeley RJ,Woods SC,Sheldon RJ

    更新日期:2003-09-01 00:00:00

  • Comparative biochemical responses of rats to different stressful stimuli.

    abstract::Adult male rats were exposed to single applications of one of three stressful stimuli (low environmental temperature, immobilization, random footshock) for periods up to 4 hours and plasma levels of corticosterone (PCS), fatty acids (PFA), and glucose (PGL) were determined at various points during the stress exposure ...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(85)90054-x

    authors: Odio MR,Maickel RP

    更新日期:1985-04-01 00:00:00

  • Chronic stress increases estrogen and other steroids in inseminated rats.

    abstract::Physical restraint, like many other stressors, can block early pregnancy, but the underlying physiological mechanisms have not been established. Exogenous estrogens in minute doses will also block early pregnancy. In the present study, female rats were exposed to 5 h of restraint daily for the first 5 days after insem...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(92)90446-9

    authors: MacNiven E,deCatanzaro D,Younglai EV

    更新日期:1992-07-01 00:00:00

  • Brain catalase activity is highly correlated with ethanol-induced locomotor activity in mice.

    abstract::It has been demonstrated that acute administration of lead to mice enhances brain catalase activity and ethanol-induced locomotion. These effects of lead seem to be related, since they show similar time courses and occur at similar doses. In the present study, in an attempt to further evaluate the relation between bra...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/s0031-9384(01)00511-x

    authors: Correa M,Sanchis-Segura C,Aragon CM

    更新日期:2001-07-01 00:00:00

  • Simultaneous measurement of endogenous steroid hormones and their metabolites with LC-MS/MS in faeces of a New World primate species, Cebus capucinus.

    abstract::We developed and validated a method to measure steroid hormones with liquid chromatography-tandem mass spectrometry (LC-MS/MS) in faecal samples of white-faced capuchins. The method includes the measurement of adrenal and gonadal hormones such as cortisol, testosterone, estrone, progesterone and a number of their faec...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2011.09.004

    authors: Weltring A,Schaebs FS,Perry SE,Deschner T

    更新日期:2012-01-18 00:00:00

  • Ileal brake: a sensible food target for appetite control. A review.

    abstract::With the rising prevalence of obesity and related health problems increases, there is increased interest in the gastrointestinal system as a possible target for pharmacological or food-based approaches to weight management. Recent studies have shown that under normal physiological situations undigested nutrients can r...

    journal_title:Physiology & behavior

    pub_type: 杂志文章,评审

    doi:10.1016/j.physbeh.2008.07.018

    authors: Maljaars PW,Peters HP,Mela DJ,Masclee AA

    更新日期:2008-10-20 00:00:00