Abstract：
OBJETIVES:Radical cystectomy is the standard treatment for localised muscle invasive bladder cancer (MIBC). We offer a bladder-sparing treatment with TURB +/- Chemotherapy+Radiotherapy to selected patients as an alternative. MATERIAL AND METHODS:We analyze, retrospectively, 30 patients diagnosed with MIBC from March 1991 to October 2010. The mean age was 62.7 years (51-74). All patients were candidates for a curative treatment, and underwent strict selection criteria: T2 stage, primary tumor, solitary lesion smaller than 5cm with a macroscopic disease-free status after TURB, negative random biopsy without hydronephrosis. Staging CT evaluation was normal. Restaging TURB or tumor bed biopsy showed a disease-free status or microscopic muscle invasion. 14 patients underwent TURB alone, 13 TURB+Chemotherapy and 3 TURB+Chemotherapy+Radiotherapy. RESULTS:The mean follow up was 88.7 months (19-220). 14 patients remained disease free (46.6%), 10 had recurrent non-muscle invasive bladder cancer (33%). 81.3% complete clinical response. 71% bladder preserved at 5-years. Overall, 5-years survival rate was 79% and 85% cancer-specific survival rate. CONCLUSIONS:Although radical cystectomy is the standard treatment for localised MIBC, in strictly selected cases, bladder-sparing treatment offers an alternative with good long term results.
journal_name
Actas Urol Espjournal_title
Actas urologicas espanolasauthors
Lendínez-Cano G,Rico-López J,Moreno S,Fernández Parra E,González-Almeida C,Camacho Martínez Edoi
10.1016/j.acuro.2013.03.004keywords:
["Bladder cancer","Bladder-sparing","Chemotherapy","Conservación vesical","Cáncer vesical","Quimioterapia","Radioterapia","Radiotherapy","Resección transuretral","Transurethral resection"]subject
Has Abstractpub_date
2014-01-01 00:00:00pages
7-13issue
1eissn
0210-4806issn
1699-7980pii
S0210-4806(13)00158-7journal_volume
38pub_type
杂志文章abstract：INTRODUCTION:The retroperitoneal surgery is the clearer indication for the laparoscopic approach. Still there are indications for open surgery because of the complexity of the patient and the surgeon experience. OBJECTIVES:The main objective is to report our experience of laparoscopic radical nephrectomies in patient ...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/s0210-4806(09)74227-5
更新日期：2009-07-01 00:00:00
abstract：BACKGROUND:To evaluate the effect of a humidity detector device on the quality of life of patients with urinary incontinence IU. METHOD:Quasi-experimental study: a series of ten cases followed for a month. The devices were placed and the questionnaires filled in before and after using it for at least ten hours a day d...
journal_title：Actas urologicas espanolas
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abstract：INTRODUCTION:Primary adenocarcinoma of the seminal vesicle is an extremely rare condition. Some cases have been described in relation to congenital seminal vesicle cysts, which is often also associated with agenesia or ipsilateral renal disgenesia. The rareness of this type of lesions makes it difficult to plan a regul...
journal_title：Actas urologicas espanolas
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abstract：INTRODUCTION:There is a need for a precise and reliable imaging to improve the management of prostate cancer. In recent years the PET/CT with choline has changed the handling of prostate cancer in Europe, and it is commonly used for initial stratification or for the diagnosis of a biochemical recurrence, although it do...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,评审
doi：10.1016/j.acuro.2016.09.015
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abstract：OBJECTIVES:Chronic bacterial prostatitis (CBP) is the most common urological disease in patients younger than 50 years, whose long-standing symptoms could be related to an inappropriate therapeutic regimen. The objective was to analyse the sensitivity of microorganisms isolated from patients with CBP and measure the we...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
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abstract：OBJECTIVE:To perform a comparative analysis of indirect and direct costs of two minimally invasive techniques (extracorporeal shock wave lithotripsy (ESWL) vs. ureteroscopy with holmium laser (URS/RIRS)) for the treatment of renal/ureteral calculi smaller than 2 cm. MATERIAL AND METHODS:Prospective, comparative, non-r...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
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abstract：BACKGROUND:Northern African (NAf) men show a high incidence of advanced prostate cancer (PCa) at diagnosis. Several studies suggested the existence of ethnic differences in the PCa aggressiveness and this has led to some concerns related to the inclusion of some ethnic groups into active surveillance protocols. OBJECT...
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pub_type： 杂志文章,多中心研究
doi：10.1016/j.acuro.2016.01.011
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abstract：:Inflammation has been implicated as an etiological factor in different human cancers. Allelic variations in the genes implicated in inflammation are candidates as genetic determinants or markers of renal carcinoma risk. The present stud investigates whether polymorphisms of the genes that give rise to increases in the...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/s0210-4806(09)74180-4
更新日期：2009-05-01 00:00:00
abstract：INTRODUCTION:Considering that BPH is a highly common condition in the urological practice, that demographic changes further emphasise this feature and that the analysis of costs, funding and health care management are becoming increasingly under scrutiny, it is important to know the cost per procedure of the most commo...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：
更新日期：1999-03-01 00:00:00
abstract：:We report a case of necrotizing granulomatous vasculitis in the spermatic cord in a 35-year-old man with an antecedent of brain stroke 3 years before. The clinical manifestation was as a painless left scrotal mass. The diagnosis was established by histological examination of the spermatic cord. We discuss the physical...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/s0210-4806(05)73340-4
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journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/s0210-4806(05)73246-0
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journal_title：Actas urologicas espanolas
pub_type： 杂志文章,评审
doi：10.1016/j.acuro.2015.03.004
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journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：
更新日期：1992-05-01 00:00:00
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journal_title：Actas urologicas espanolas
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：
更新日期：1993-03-01 00:00:00
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journal_title：Actas urologicas espanolas
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journal_title：Actas urologicas espanolas
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更新日期：1995-05-01 00:00:00
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pub_type： 杂志文章
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更新日期：1987-09-01 00:00:00
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journal_title：Actas urologicas espanolas
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journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/j.acuro.2013.12.013
更新日期：2014-09-01 00:00:00
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pub_type： 杂志文章,随机对照试验
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journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：
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journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：
更新日期：1990-05-01 00:00:00
