Abstract：
BACKGROUND:Northern African (NAf) men show a high incidence of advanced prostate cancer (PCa) at diagnosis. Several studies suggested the existence of ethnic differences in the PCa aggressiveness and this has led to some concerns related to the inclusion of some ethnic groups into active surveillance protocols. OBJECTIVE:To evaluate pathological outcomes and aggressiveness of low risk PCa treated by radical prostatectomy in a NAf ethnic group. SUBJECTS AND METHODS:Data of 147 NAfs, who underwent radical prostatectomy for low risk PCa diagnosed via a 12-core biopsy in 2 academic centers between 2011 and 2015, were reviewed retrospectively to assess rates of worse pathological outcomes defined as: Gleason score upgrade to at least 3+4, upstage to pT3a or higher or pN1, and positive surgical margins. RESULTS:Overall significant upstage and/or upgrade occurred in 20.2% and positive surgical margins occured in18.3%. In multivariate logistic regression analysis, independent variables that predicted for upstage and/or upgrade or positive surgical margins in the entire cohort were: NCCN risk group (low risk>very low risk), advanced age>60 years, PSA>6ng/ml, PSA density≥0.15, more than 2 positive cores in biopsy, more than 50% cancer involvement in positive cores, clinical stage (T2a>T1c) and UCSF-CAPRA-S score>3. CONCLUSIONS:Our study found that, at least pathologically, NAf men do not have more aggressive disease than Caucasians and African Americans in both low and very low risk PCa. Thus, we think that active surveillance is a suitable approach for selected patients since there is no definitive data that show a more aggressive natural history of PCa in NAf men.
journal_name
Actas Urol Espjournal_title
Actas urologicas espanolasauthors
Ammani A,Janane A,Bouzide B,Dehayni Y,Lezrek M,Ghadouane M,Ameur A,Abbar M,Qarro A,Alami Mdoi
10.1016/j.acuro.2016.01.011subject
Has Abstractpub_date
2016-11-01 00:00:00pages
556-563issue
9eissn
0210-4806issn
1699-7980pii
S0210-4806(16)30006-7journal_volume
40pub_type
杂志文章,多中心研究abstract：OBJECTIVE:Analysis of the urinary excretion of cytokines in vesical carcinoma. MATERIAL AND METHOD:The study includes the results obtained in the quantification of several interleukins (IL-1, IL-2, IL-4, IL-6, INF-gamma and TNF-alpha) in urine samples corresponding to 60 patients with transitional cell carcinoma (TCC)...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：
更新日期：1997-05-01 00:00:00
abstract：:The Mitomycin C is a chemotherapeutic agent used in several types of carcinomas. In the superficial vesical carcinoma comes using since more than a quarter century in the form of endovesical instillations. It is a drug relatively safe, although there have been described adverse effects related to its systemic administ...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/s0210-4806(09)74237-8
更新日期：2009-07-01 00:00:00
abstract：:Presentation of one case of a 40 year-old, homosexual, AIDS diagnosed male with extrapulmonary tuberculosis (lymphatic nodes) and prior history of gonococcal urethritis, brain toxoplasmosis, molluscum contagiosum and pneumonia by Pneumocystis carinii. A purpura-type lesion with inflammatory features appeared in the fo...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,评审
doi：
更新日期：1993-05-01 00:00:00
abstract：:We present our case study of 100 penile prostheses in patients suffering from erectile sexual dysfunction of different etiologies. We carry out a review of the different diagnostic stages and the different surgical approaches for prosthetic implant and their complications. ...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,评审
doi：
更新日期：1989-11-01 00:00:00
abstract：:Penoscrotal lymphedema is a rare disease in the developed countries, although it is relatively frequent in tropical countries. The most common cause is filariasis, although in our practice usually is associate to neoplasic and inflammatory processes, surgery, radiotherapy, hidroelectrolitic disbalances and idiopathic....
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/s0210-4806(05)73285-x
更新日期：2005-05-01 00:00:00
abstract：:As a novel item we present a case of the reconversion of a Bricker-Wallace type external urinary bypass into vesical replacement according to Camey technique type II. 5 years after radical cystectomy and external urinary bypassing due to a malignant infiltrating vesical carcinoma and considering the patient's malignan...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：
更新日期：1990-01-01 00:00:00
abstract：INTRODUCTION:Umbilical laparoendoscopic single-site (LESS) surgery represents an excellent alternative to laparoscopic or robotic multiport surgery. LESS surgery offers faster recovery, less postoperative pain and optimal cosmetic results. LESS is possible in virtually any urologic surgery. PATIENT AND METHOD:We prese...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/j.acuro.2014.07.004
更新日期：2015-05-01 00:00:00
abstract：:Exposition of one case of fibroepithelial polyp of the ureter in a young male patient. The interest of the case lies in the rarity of this entity. Review of all likely etiologies, clinical presentations and differential diagnosis, mainly with malignant tumours whose prognosis and treatment are entirely different. Endo...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：
更新日期：1994-10-01 00:00:00
abstract：:There are several causes for orchitis and among them there are inflammatory process. We want to communicate the case of a young man with a clinical history and physical examination compatible with orchitis produced by the extension of a pancreatic pseudocyst that was not suspected in the beginning and discovered by im...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/s0210-4806(08)73824-5
更新日期：2008-02-01 00:00:00
abstract：:The paper presents the case of a patient with isolated testicular relapse (ITR), after a period of complete continuous remission (CCR) following chemotherapy, cobalt-therapy and bone marrow transplant (BMT) due to diagnosis of acute type T lymphoblastic leukemia L1. A review of literature regarding treatment of these ...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：
更新日期：1990-03-01 00:00:00
abstract：INTRODUCTION:Bladder cancer is a disease with a high prevalence due to its recurrence rate. Transurethral resection of the bladder (TURB) is the treatment in initial stages. Nevertheless, a high percentage of non-muscle-invasive tumors treated will have a recurrence 1-2 years afterwards. Adjuvant quemotherapy or immuno...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,随机对照试验
doi：10.1016/s0210-4806(08)73940-8
更新日期：2008-09-01 00:00:00
abstract：:The etiology of retroperitoneal masses that can compress the bladder or the ureters and can result in urinary sings and symptoms is highly varied and may include both benign and malignant entities. This paper contributes one patient that presented with relapsing retrovesical mass with cystic features. The diagnosis fr...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,评审
doi：
更新日期：1999-05-01 00:00:00
abstract：INTRODUCTION:Nephroureterectomy is one of the procedures for which a laparoscopic approach is more clearly indicated. However, despite the long experience available, management of the distal ureter is still difficult. MATERIALS AND METHODS:Thirty-two laparoscopic nephroureterectomies were performed from November 2004 ...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：
更新日期：2010-02-01 00:00:00
abstract：:Fifty-one patients with non-seminoma testicular cancer who underwent retroperitoneal ganglion dissection and 3 support cycles of chemotherapy with Cys-Platin, Vinblastine and Bleomycin. Four patients presented relapses (7.8%). Actuarial survival by 8 years was 87%, with a median of 38 months. The median survival was 4...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：
更新日期：1989-01-01 00:00:00
abstract：INTRODUCTION:San Antonio, Somacarrera (1977) and Rousaud-Inmark (1984) studies established the first data of incidence and prevalence about urolithiasis in Spain. Other regional or national epidemiologic details were given for several authors from 1977 to 2002. MATERIAL AND METHOD:Sixteen papers with original data abo...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,评审
doi：10.1016/s0210-4806(07)73675-6
更新日期：2007-05-01 00:00:00
abstract：OBJECTIVES:Analyze the role of the Computerized Axial Tomography (TAC) like image study of pre-surgery stadification, in the subjected patients to radical cystectomy, for the treatment of muscle infiltrate bladder cancer. METHODS:Retrospective study of cohorts on 63 subjected patients to radical cystectomy for bladder...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/s0210-4806(08)73874-9
更新日期：2008-05-01 00:00:00
abstract：INTRODUCTION:primary hyperaldosteronism is one of the few potentially curable causes of secondary arterial hypertension. One of the most important variants is the adenoma of the adrenal cortex that produces aldosterona (Conn's Syndrome). The treatment of choice in this subgroup of patients was the removal of the lesion...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/j.acuro.2010.11.009
更新日期：2011-02-01 00:00:00
abstract：OBJECTIVE:To know the prevalence of the bilateral germ cell tumours of testis diagnosed in our Department and to review the literature. MATERIAL AND METHODS:64 patients diagnosed of a germ cell tumour of the testis were followed during an average period of 51.4 months (1-168 months). RESULTS:5 (7.8%) patients develop...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,评审
doi：10.1016/s0210-4806(00)72516-2
更新日期：2000-09-01 00:00:00
abstract：INTRODUCTION:In November of 1998, the Spanish Association of Urology decides to carry out a study on the lithotripsy in Spain, through the Group of Work in Lithiasis Urinary, with the objective of knowing the n(o) and distribution of Units and the real situation of the extracorporeal litotripsy for shock waves, in conn...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/s0210-4806(00)72531-9
更新日期：2000-10-01 00:00:00
abstract：INTRODUCTION:To prevent the overdiagnosis and overtreatment of prostate cancer (PC), therapeutic strategies have been established such as active surveillance and focal therapy, as well as methods for clarifying the diagnosis of high-grade prostate cancer (HGPC) (defined as a Gleason score ≥7), such as multiparametric m...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/j.acuro.2015.09.006
更新日期：2016-04-01 00:00:00
abstract：:The stromal component of the urethral caruncle (UC) comprises a mixture of inflammatory, vascular, and fibrotic phenomena. Although mastocytes are cell elements known to appear in relation with chronic inflammation, there is no data in the literature explaining their significance in UCs or their ultrastructure relatio...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：
更新日期：1993-07-01 00:00:00
abstract：INTRODUCTION AND OBJECTIVES:The aim of this study was to analyse prognostic impact of tumour histological grade on survival differences between primary G2 and G3 WHO1973 stage T1 tumours which were graded as HG according to WHO2004 grading system. MATERIALS AND METHODS:Data from 481 patients with primary T1HG bladder ...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,多中心研究
doi：10.1016/j.acuro.2019.03.011
更新日期：2019-11-01 00:00:00
abstract：:Retrocaval ureter is a rare disease in childhood which is due to a abnormal development of the inferior cava vein. We report a new case of retrocaval ureter in a 9 year-old girl who had consulted for macrohematuria and right flank pain. Preoperative intravenous urography and DTPA diuretic renogram suggested this entit...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：
更新日期：1998-10-01 00:00:00
abstract：:We presented a case of inferior vena cava on the left side diagnosed by abdominal CT scan during the study of a renal cell carcinoma in the right side. This anomaly is very rare but it may suppose a more difficult approach to the nephrectomy. ...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/s0210-4806(05)73320-9
更新日期：2005-07-01 00:00:00
abstract：:Presentation of one case of soft lithiasis in a child which was treated by pyelolithectomy with good results and which has not relapsed after a 20-year follow-up. A commented revision is made of related literature. ...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,评审
doi：
更新日期：1994-05-01 00:00:00
abstract：:A case of unilateral cavernosal body abscess appears after fifteen days of 40 degrees C fever, without urological symptoms. The diagnosis started from a big scrotum aedema, related of a local septic focus in the left cavernosal body. ECO and TAC confirmed the diagnosis, and a surgical treatment was required. After a s...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/s0210-4806(03)72877-0
更新日期：2003-01-01 00:00:00
abstract：:Male feminization is an uncommon and complex phenomenon which occurs as a consequence of an imbalance in the effective oestrogen/androgen relationship. One of the many approaches used in the treatment of idiopathic male infertility is hCG/hMG stimulation. This paper reports one case of an infertile male treated with h...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,评审
doi：
更新日期：1995-05-01 00:00:00
abstract：OBJECTIVE:To comment on the most relevant aspects and to review the literature on this unusual pathology. MATERIAL AND METHODS:We present two cases of cystic lymphangioma, their clinical, diagnosis, therapy and development, and we review the actual literature. The first case is a young man with the diagnosis of cystic...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,评审
doi：10.1016/s0210-4806(06)73525-2
更新日期：2006-07-01 00:00:00
abstract：:During the first ten years (1981-1990) of our organ transplantation program a total of 395 Renal Transplants (RTx) have been carried out in our Unit, 90 of which in 88 patients had to be subsequently transplantectomized. In 32 of them the reason was acute rejection (35%) including 7 renal rhexis, and in 30 chronic rej...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：
更新日期：1992-01-01 00:00:00
abstract：:Twenty-nine male children with urethral stenosis, with ages between 7 months and 18 years, were treated by endoscopic surgery. The etiology of their condition was trauma in 21 cases and congenital in 8. Location of the stenosis corresponded in 18 cases to membranous urethra, 7 to bulbar urethra, 2 to penial urethra wh...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：
更新日期：1994-05-01 00:00:00
