Abstract:
OBJECTIVES:Chronic bacterial prostatitis (CBP) is the most common urological disease in patients younger than 50 years, whose long-standing symptoms could be related to an inappropriate therapeutic regimen. The objective was to analyse the sensitivity of microorganisms isolated from patients with CBP and measure the weekly antibiotic concentrations in serum, semen and urine. MATERIAL AND METHODS:For the antibiotic sensitivity study, 60 clinical isolates were included between January 2013 and December 2014 from semen samples from patients with microbiologically confirmed CBP. Broth microdilution was performed on the samples. For the antibiotic concentration study from January to May 2014, urine, blood and semen samples were collected weekly, over 4 weeks of treatment from 8 patients with positive cultures for CBP. The concentrations were measured using ultra-high performance liquid chromatography coupled to tandem mass spectrometry (UHPLC-MS/MS). RESULTS:The antibiotics fosfomycin and nitrofurantoin had the highest activity (95.2% in both cases). The mean antibiotic concentrations in semen during the 4 weeks studied were as follows: 1.68mg/L, 8.30mg/L, 2.61mg/L, 0.33mg/L and 2.90mg/L, respectively, for patients 1 to 5, who were treated with levofloxacin; 1.625mg/L for patient 6, who was treated with ciprofloxacin; 2.67mg/L for patient 7, who was treated with ampicillin; and 1.05mg/L for patient 8, who was treated with doxycycline. Higher concentrations were obtained in the urine samples than in serum and semen, the latter 2 of which were comparable. CONCLUSIONS:Fosfomycin is proposed as the primary alternative to the empiric treatment of CBP due to its high in vitro activity. The antibiotic concentration in semen was higher than the minimal inhibitory concentration against the aetiological agent, although microbiological negativisation was not always correlated with a favourable clinical outcome.
journal_name
Actas Urol Espjournal_title
Actas urologicas espanolasauthors
Heras-Cañas V,Gutiérrez-Soto B,Almonte-Fernández H,Lara-Oya A,Navarro-Marí JM,Garrido-Frenich A,Vázquez-Alonso F,Gutiérrez-Fernández Jdoi
10.1016/j.acuro.2017.03.008subject
Has Abstractpub_date
2017-12-01 00:00:00pages
631-638issue
10eissn
0210-4806issn
1699-7980pii
S0210-4806(17)30089-Xjournal_volume
41pub_type
杂志文章abstract:OBJECTIVE:Evaluation the diagnostic ability of unenhanced helical computed tomography in the evaluation of patients with acute flank pain. PATIENTS AND METHODS:Prospectively evaluation of 82 patients referred for acute flank pain between january 1999 and june 2000. 78 patients were imaged with, 73 abdominal ultrasound...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章
doi:10.1016/s0210-4806(01)72692-7
更新日期:2001-10-01 00:00:00
abstract::We show a big renal cell carcinoma case in an aged woman with many pathology associated. In view of the family refuse to make the radical surgery and the high surgical risk we decided to apply transarterial embolization treatment with polivinil alcohol particles (PVA). 28 months later the patient becames with no sympt...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章
doi:10.1016/s0210-4806(05)73246-0
更新日期:2005-03-01 00:00:00
abstract:INTRODUCTION:The Bladder neck cerclage diminishes the risk of bleeding after transvesical prostatectomy, but it increases the risk of suffering postoperative bladder neck sclerosis. Our objective is to value the effectiveness and therapeutic security of the temporary bladder neck cerclage after transvesical prostatecto...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章
doi:10.1016/s0210-4806(06)73396-4
更新日期:2006-01-01 00:00:00
abstract::Description of 17 cases of columns of Bertin's hypertrophy found by chance while performing 587 urological ecographies carried out while following other urogenital diagnostic approaches. The present report is prompted by the entity's features and the differential diagnosis forced by the "renal mass effects". A series ...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章
doi:
更新日期:1991-05-01 00:00:00
abstract:OBJECTIVE:To assess the safety of hospital discharge 24 hours after laparoscopic radical prostatectomy and to identify possible factors associated with longer hospital stays. MATERIAL AND METHODS:Retrospective study of patients diagnosed with localized prostate cancer underwent to laparoscopic radical prostatectomy co...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章
doi:10.1016/j.acuro.2013.12.004
更新日期:2014-07-01 00:00:00
abstract:INTRODUCTION:The prostate cancer is an important cause of men's mortality in our society. PURPOSE:To know the time of delay in to realise the surgical treatment of the prostate cancer. MATERIALS AND METHODS:Analysis of 30 cases of patients treated with radical prostatectomy, cuantifying the time of delay in all the p...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章,评审
doi:10.1016/s0210-4806(03)72922-2
更新日期:2003-04-01 00:00:00
abstract::An asymptomatic case of cystic renal carcinoma is presented. The only diagnosis of certainty was given by a marked increase in L.D.H. levels in the fluid of the tumor after puncture. The pros and cons of imaging studies, and the relative lack of value of aspiration cytology when negative results are encountered are di...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章
doi:
更新日期:1989-05-01 00:00:00
abstract::Report on the results of a survey conducted among Urology residents in the Valencian Community. Evaluation of the training level of the MIR system, both overall and by areas. Presentation of the views obtained with regard to possible modifications to raise their training level and improve their professional future. ...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章
doi:
更新日期:1998-03-01 00:00:00
abstract::Presentation of a malignant rhabdoid renal tumour. This type of sarcoma which occurs commonly during the paediatric age is exceptional in the adult, this being the reason for reviewing this clinical case and its management. The term rhabdoid includes several types of morphologically similar tumours which make analysis...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章
doi:
更新日期:1996-04-01 00:00:00
abstract:OBJECTIVES:To perform the linguistic and psychometric validation of the Spanish version of the BSW (Benefit, Satisfaction and Willingness to continue) questionnaire. MATERIAL AND METHODS:Epidemiologic, observational, multicenter, prospective (October 2008-February 2009) study in patients ≥40 years old with de novo ove...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章,多中心研究
doi:10.1016/j.acuro.2013.03.005
更新日期:2013-09-01 00:00:00
abstract:OBJECTIVE:To present our experience in both uni-and bilateral priapism, highlighting good results obtained with supraselective embolisation. MATERIAL AND METHODS:We present 5 cases of high-flow priapism secondary to perineal trauma, with a mean age of 31 years (24-43 years). The mean time to presentation from the mome...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章
doi:10.1016/s0210-4806(07)73608-2
更新日期:2007-02-01 00:00:00
abstract:INTRODUCTION:It has been reported that varicocele might promote angiogenesis. However, it is not clearly identified how angiogenesis affect testicular morphology or spermatogenic activity. The objective of the study is to investigate the effect of spironolactone, as an angiogenesis inhibitor, on the ipsilateral testis ...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章
doi:10.1016/j.acuro.2013.12.013
更新日期:2014-09-01 00:00:00
abstract::Lymphoma involving the prostate is rare, both as a primary and as a secondary presenting. Usually the prognosis remains poor. The clinical presentation is similar to that of other lower urinary tract obstructions, in fact prostatic lymphoma must be considered in patients with these symptoms, particularly in patients w...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章,评审
doi:10.1016/s0210-4806(02)72807-6
更新日期:2002-06-01 00:00:00
abstract:BACKGROUND:Taking into account the high prevalence in our country of Overactive Bladder Syndrome (OAB) ("urgency", with or without incontinence, sometimes associated to an increase in frequency and/or nocturia) and the difficulty to identify it, it would be interesting to have a short patient self assessment screening ...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章
doi:10.1016/s0210-4806(06)73578-1
更新日期:2006-11-01 00:00:00
abstract:CONTEXT:This article reviews diverse aspects of the prevention of urinary tract infections, including confirmation of the diagnosis, application of hygiene and dietary measures, antibacterial prophylaxis (preferably consisting of a single nocturnal oral dose per day of an antibiotic or drug with high urinary excretion ...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章,评审
doi:10.1016/j.acuro.2011.05.002
更新日期:2012-01-01 00:00:00
abstract:INTRODUCTION:The association between testosterone and prostate cancer badly is understood. The testosterone levels are not conclusive to distinguish benign prostate processes of malignant. The objective of our work is to determine the relation between levels of serum testosterone and prostate cancer. MATERIAL AND METH...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章
doi:
更新日期:2003-11-01 00:00:00
abstract:INTRODUCTION:Absolute priority in an LDKT programme are donnor safety and kidney optimal anatomical and functional preservation. Reduced donnor morbidities, both at short and long term, are important objectives. Excellent technical grafting is a must as are the strategies employed for facilitatig it. We revised the inc...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章
doi:10.1016/s0210-4806(08)73977-9
更新日期:2008-11-01 00:00:00
abstract::Report on the presence in 43 patients of various foreign materials left in the urinary tract following a surgical procedure. The clinical symptoms exhibited by these patients correspond to a urinary syndrome with irritation or lumbar pain when the foreign body blocked the upper urinary tract. In most cases, diagnosis ...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章,评审
doi:
更新日期:1991-09-01 00:00:00
abstract::Presentation of one case of hyporreflexic bladder like a first step of neurotoxicity due to Vinca alkaloids. These drugs produces peripheral neuropathies as usual, but in some rare occasions they may affect to the autonomic nervous system with its effects in the bladder producing hyporreflexic. This disease reverts sp...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章
doi:10.1016/s0210-4806(00)72447-8
更新日期:2000-03-01 00:00:00
abstract::There is an increasement on the incidence of tumours within the population of renal transplanted, from three to five times over general population. Related to urological tumours, it emphasizes an increase in the incidence of the renal carcinoma, around 4,7% against 3% on general population. In this case, we present a ...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章
doi:10.1016/s0210-4806(09)74007-0
更新日期:2009-01-01 00:00:00
abstract:CONTEXT:The objective of evidence-based medicine is to employ the best scientific information available to apply to clinical practice. Understanding and interpreting the scientific evidence involves understanding the available levels of evidence, where systematic reviews and meta-analyses of clinical trials are at the ...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章
doi:10.1016/j.acuro.2018.01.010
更新日期:2018-10-01 00:00:00
abstract::In Spain, based on the IIEF, 19% of males between 25 and 70 years old present some degree of erectile dysfunction (ED). Therefore, around 2,000,000 Spanish men present this condition and could require medical attention for it. Here, we present an up-date of the most important aspects of erectile dysfunction (pathophys...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章,评审
doi:10.1016/s0210-4806(02)72844-1
更新日期:2002-10-01 00:00:00
abstract::Review of 158 cases of renal traumatism attended ar the Urology Service of "La Fe" Hospital from 1984 to 1995. We analyze the indications of radiological study of the polytraumatized patient, the different classifications of renal traumatism and the changes produced in the diagnosis protocol, after substituting urogra...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章,评审
doi:
更新日期:1996-06-01 00:00:00
abstract::Presentation of the case of a 23-year old male diagnosed with bilateral renal angiomyolipomas associated to florid tuberous sclerosis, who presented with intense haematuria. The patient was treated conservatively by means of arterial selective embolization, later followed by nephrectomy due to persistence of bleeding....
journal_title:Actas urologicas espanolas
pub_type: 杂志文章
doi:
更新日期:1994-02-01 00:00:00
abstract::Instrumentation of lower urinary tract is a predisposing factor for the development of urinary infection. Incidence of infective complications following urethrocystoscopy has been evaluated in a multicenter, prospective, comparative and randomized study in 2,284 patients, who had a previous negative urine culture. Pat...
journal_title:Actas urologicas espanolas
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:
更新日期:1993-03-01 00:00:00
abstract::A case is presented on the use of extracorporeal lithotrity by shock waves to treat vesical lithiasis, using the desk module of a Lithostar-PlusR (Siemens) lithotripter. This is an effective method without morbidity an adequate for ambulatory use, specially valuable in patients where the use of more invasive methods, ...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章
doi:
更新日期:1990-11-01 00:00:00
abstract::Granulomatous orchitis is an inflammatory change of the testis. This is a rare lesion of unknown etiology. Usually are unilateral. The clinical appearance varies, and it is difficult to differentiate from testicular cancer. The diagnosis usually being made on histological examination after orchiectomy. Our paper repor...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章
doi:10.1016/s0210-4806(00)72526-5
更新日期:2000-09-01 00:00:00
abstract:INTRODUCTION:Open adenomectomy (OA) is the surgery of choice for large volume benign prostatic hyperplasia, and laparoscopic adenomectomy (LA) represents a minimally invasive alternative. We present a long-term, prospective study comparing both techniques. PATIENTS AND METHODS:The study consecutively included 199 pati...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章
doi:10.1016/j.acuro.2016.04.008
更新日期:2017-01-01 00:00:00
abstract:INTRODUCTION AND OBJECTIVES:Prostate stones are frequently encountered during transurethral resection of the prostate in urology practice. We aimed to demonstrate the physical and chemical properties of prostate stones. We also aimed to determine possible relationship between inflammation of prostate gland and prostate...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章
doi:
更新日期:2010-06-01 00:00:00
abstract:OBJECTIVES:To create a relational database for monitoring lithiasic patients. We describe the architectural details and the initial results of the statistical analysis. METHODS AND MATERIALS:Microsoft Access 2002 was used as template. Four different tables were constructed to gather demographic data (table 1), clinica...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章
doi:
更新日期:2010-05-01 00:00:00