Abstract：
INTRODUCTION:It has been reported that varicocele might promote angiogenesis. However, it is not clearly identified how angiogenesis affect testicular morphology or spermatogenic activity. The objective of the study is to investigate the effect of spironolactone, as an angiogenesis inhibitor, on the ipsilateral testis morphology in left varicocele-induced rats. MATERIALS AND METHODS:Twenty four adult (12-14 mo), male Wistar albino rats were randomly assigned to four groups (n=6, for each): 1. Control group, 2. Sham-operated group, 3. Experimental left varicocele group and, 4. Spironolactone (20mg/kg/day)-treated experimental left varicocele group. Histopathological findings in rat testis were investigated. RESULTS:Microvessel density increased in varicocele group and spironolactone inhibited angiogenesis neither by antimineralocorticoid, nor by antiandrogenic effect. However, spermatogenesis impaired in spironolactone treated varicocele group. CONCLUSION:Angiogenesis seems to be a protective process in varicocele. Spironolactone treatment, probably by inhibiting angiogenesis, impairs testicular morphology.
journal_name
Actas Urol Espjournal_title
Actas urologicas espanolasauthors
Gökhan-Köse M,Erdem ŞR,Peşkircioğlu ÇL,Çaylak Bdoi
10.1016/j.acuro.2013.12.013subject
Has Abstractpub_date
2014-09-01 00:00:00pages
459-64issue
7eissn
0210-4806issn
1699-7980pii
S0210-4806(14)00069-2journal_volume
38pub_type
杂志文章abstract：:Presentation of the analytical results from the patients seen for lithiasic disease (LD) over a two-year period at the Hospital Reina Sofia, Tudela. This Hospital covers a homogeneous Health Area including 22 villages and a population of 76,000 people. The clinical cases of 785 patient diagnosed with LD between May 19...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：
更新日期：1995-09-01 00:00:00
abstract：OBJECTIVES:To analyse the learning curve for the management of tyrosine kinase inhibitors as the first line of treatment for patients with metastatic renal cancer. MATERIAL AND METHODS:We evaluated 32 consecutive patients treated in our department for metastatic renal cancer with tyrosine kinase inhibitors (pazopanib ...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/j.acuro.2018.01.004
更新日期：2018-03-07 00:00:00
abstract：:From the Second World War onwards an amazing development in science and clinical & surgery practice has taken place: antibiotics, blood storage, cardiac surgery, organ and tissue transplant, complete joint replacement, total intravenous nutrition or minimally invasive surgery. Paradoxically, during the last two decade...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,评审
doi：10.1016/s0210-4806(08)73792-6
更新日期：2008-01-01 00:00:00
abstract：PURPOSE:To evaluate the peri- and post-surgical complications in Renal Adenocarcinoma (RAC) treated with Radical Nephrectomy (RN). MATERIAL AND METHOD:Revision of 109 patients with RAC who underwent transperitoneal anterior abdominal RN. Patients were locally staged post-surgically as: T1 + T2 61.5%, T3a 22.9%, T3ab 1...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：
更新日期：1997-01-01 00:00:00
abstract：CONTEXT:Interest in having alternatives in the treatment of benign prostate hyperplasia. OBJECTIVES:To assess the efficacy and safety of the Urolift® system for treating the symptoms of benign prostate hyperplasia. ACQUISITION OF EVIDENCE:Systematic review of the literature through searches on PubMed, Cochrane Librar...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,评审
doi：10.1016/j.acuro.2014.05.010
更新日期：2015-06-01 00:00:00
abstract：:We make an evaluation of 66 ureteroscopies (URS) carried out in our Service over a period of 18 months. In 55 cases it was done for therapeutic purposes in ureteral lithiasis, and in 11 cases it was for diagnostic purposes. In the treatment of lithiasis resolutive effectivity at the first attempt was 68%, in 9% ureter...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：
更新日期：1990-01-01 00:00:00
abstract：INTRODUCTION:Laparoscopic nephron-sparing surgery is among the most complex urological procedures currently performed. Open surgery continues to be the gold standard of care, but the laparoscopic approach is gaining ground slowly but surely. Our 5 years' experience is reported. MATERIALS AND METHODS:From September 200...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：
更新日期：2010-03-01 00:00:00
abstract：:Our service performed a total of 619 kidney transplants between February 1980 and March 1993. Among them, 41 new neoplasias (6.6%) were diagnosed. Most frequent tumour was epithelioma (25) with a presentation age lower than in the normal population. Amongst the remaining tumours (16), the occurrence of 2 lymphoma and ...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：
更新日期：1994-05-01 00:00:00
abstract：:A case of unilateral cavernosal body abscess appears after fifteen days of 40 degrees C fever, without urological symptoms. The diagnosis started from a big scrotum aedema, related of a local septic focus in the left cavernosal body. ECO and TAC confirmed the diagnosis, and a surgical treatment was required. After a s...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/s0210-4806(03)72877-0
更新日期：2003-01-01 00:00:00
abstract：OBJECTIVE:To perform a comparative analysis of indirect and direct costs of two minimally invasive techniques (extracorporeal shock wave lithotripsy (ESWL) vs. ureteroscopy with holmium laser (URS/RIRS)) for the treatment of renal/ureteral calculi smaller than 2 cm. MATERIAL AND METHODS:Prospective, comparative, non-r...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/j.acuro.2020.03.008
更新日期：2020-09-01 00:00:00
abstract：:Presentation of four cases of keratinizing squamous metaplasia (KSM), two of the renal pelvis, one pyelocaliceal and one ureteral. Nephrouretetectomy was performed in all cases. All our patients showed good evolution. A review of the literature is made discussing all the etiological, diagnostic and therapeutical aspec...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,评审
doi：
更新日期：1994-09-01 00:00:00
abstract：:In renal transplant patients, an increased risk of cancer has been seen, higher than in the general population, and the more frequent genitourinary neoplasms are the kidney and bladder ones. Moreover, in those patients the pattern of tumor growth is very rapid, with early tendency to local and systemic dissemination. ...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/s0210-4806(00)72426-0
更新日期：2000-02-01 00:00:00
abstract：UNLABELLED:In order to make a measure of quality of life related to health (QLRH) useful in the investigation, it must fulfill the psychometric properties (validity, reliability and sensibility). The selection of an instrument is a job for the clinic that must choose the most effective for each proposed objective. We s...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,多中心研究
doi：10.1016/s0210-4806(02)72784-8
更新日期：2002-05-01 00:00:00
abstract：OBJECTIVES:An open, non-comparative, multicenter study was performed to ascertain the prevalence in Spain of erectile dysfunction (ED) associated to benign prostatic hypertrophy (BPH), with moderate to severe urinary symptoms, and to confirm the improvement or disappearance of ED in response to treatment with 4 mg/day ...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,多中心研究
doi：10.1016/s0210-4806(04)73077-6
更新日期：2004-04-01 00:00:00
abstract：:Between 1975-1991, a total of 557 cases of bladder carcinoma were identified in the Autonomous Community of La Rioja (CAR) which were followed up to December 1994. The overall lethality was 21.9%. 492 cases with 22.35% lethality were identified in males. In females, however, there was 65 cases with 18.46% lethality. T...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：
更新日期：1998-07-01 00:00:00
abstract：:Estimation of prostate volume is one of the key elements in the study and management of both prostate benign diseases and prostate cancer. Of the available techniques, transrectal ultrasound presents greater reliability in prostatic imaging due to its degree of resolution. The present study conducted in 40 patients un...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：
更新日期：1994-05-01 00:00:00
abstract：:Granulomatous orchitis is an inflammatory change of the testis. This is a rare lesion of unknown etiology. Usually are unilateral. The clinical appearance varies, and it is difficult to differentiate from testicular cancer. The diagnosis usually being made on histological examination after orchiectomy. Our paper repor...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/s0210-4806(00)72526-5
更新日期：2000-09-01 00:00:00
abstract：:Basic semen tests nowadays contain no variables that may allow to certify that a man is fertile. Starting from this premise it could be clinically very useful, for the diagnosis of male infertility, to evaluate a parameter that may be related to sexual maturity and be specific of the germinal tissue, such as the C4-la...
journal_title：Actas urologicas espanolas
pub_type： 临床试验,杂志文章
doi：
更新日期：1996-11-01 00:00:00
abstract：UNLABELLED:Pelvic physical therapy focuses on the prevention and the treatment of all kinds of functional disorders of the abdominal, pelvic and low back region, like urinary incontinence, that is considered as a high prevalent health problem in women, men, children and the elderly. Physical therapy is often considered...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,评审
doi：10.1016/s0210-4806(06)73412-x
更新日期：2006-02-01 00:00:00
abstract：INTRODUCTION:The retroperitoneal surgery is the clearer indication for the laparoscopic approach. Still there are indications for open surgery because of the complexity of the patient and the surgeon experience. OBJECTIVES:The main objective is to report our experience of laparoscopic radical nephrectomies in patient ...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/s0210-4806(09)74227-5
更新日期：2009-07-01 00:00:00
abstract：INTRODUCTION:To prevent the overdiagnosis and overtreatment of prostate cancer (PC), therapeutic strategies have been established such as active surveillance and focal therapy, as well as methods for clarifying the diagnosis of high-grade prostate cancer (HGPC) (defined as a Gleason score ≥7), such as multiparametric m...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/j.acuro.2015.09.006
更新日期：2016-04-01 00:00:00
abstract：:An attempt has been made to identify the epidemiological factors associated with occurrence of biologically aggressive vesical tumours. In the Autonomous Community of La Rioja, a survey was conducted between 1975-1991 of incidental vesical tumours, recording in each case the patient's sex, age and occupation. It was f...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：
更新日期：1994-11-01 00:00:00
abstract：:Bladder hernia is a very uncommon but not exceptional condition. It tends to occur in adult patients over 50, and is favoured by a cervical-urethral obstruction. It is often diagnosed during inguinal hernia surgery, although in other cases pre-operative diagnosis can be achieved through radiological studies (filling c...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,评审
doi：
更新日期：1999-07-01 00:00:00
abstract：:Male feminization is an uncommon and complex phenomenon which occurs as a consequence of an imbalance in the effective oestrogen/androgen relationship. One of the many approaches used in the treatment of idiopathic male infertility is hCG/hMG stimulation. This paper reports one case of an infertile male treated with h...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,评审
doi：
更新日期：1995-05-01 00:00:00
abstract：:Renal actinomycosis is rarely suspected and is difficult to diagnose, limited to a few cases in any series. A 56-year-old man with renal actinomycosis and Rendu-Osler disease is described. Long-term therapy with penicillin resulted in a clinical cures. A case report is presented. ...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：
更新日期：1991-11-01 00:00:00
abstract：:Report of a case of vesical adenocarcinoma of the rarely occurring signet-ring cell type, characterized by an insidious development, predominance of urination disorders, submucosal growth, late diagnosis and very poor prognosis since it is not susceptible to radiotherapy or chemotherapy. ...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：
更新日期：1991-07-01 00:00:00
abstract：:Significant conceptual changes have taken place in renal tumoral diseases over the last few years. As a result of the authors' broad institutional experience, this overall revision describes the most up-to-date clinical and diagnostic aspects of this condition. Emphasis is made on molecular staging and two variables t...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,评审
doi：10.1016/s0210-4806(02)72825-8
更新日期：2002-09-01 00:00:00
abstract：:A series of 17 patients with primary adrenal cortical carcinoma is presented. Of 14 patients without evidence of disseminated disease prior to radical surgery, 6 developed distant metastases during follow-up. The mean interval free of disease in these patients was 12 months (range 3-40) and the median survival 15 mont...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：
更新日期：1993-01-01 00:00:00
abstract：:The purpose of this retrospective study is to evaluate the incidence of prostate cancer in symptomatic patients with non-suspect rectal examination and its correlation to PSA, PSAD levels and ultrasound findings. A total of 235 patients with non-suspect rectal examination underwent transrectal ultrasound and echo-guid...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：
更新日期：1997-06-01 00:00:00
abstract：CONTEXT:The objective of evidence-based medicine is to employ the best scientific information available to apply to clinical practice. Understanding and interpreting the scientific evidence involves understanding the available levels of evidence, where systematic reviews and meta-analyses of clinical trials are at the ...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/j.acuro.2018.01.010
更新日期：2018-10-01 00:00:00
