Abstract：
CONTEXT:Serum testosterone is mostly bound to the sex hormone-binding globulin and albumin. A small metabolically active part is present in the form of free testosterone (FT). The relationship between serum total testosterone (TT) levels and prostate carcinogenesis is debated. Our hypothesis is that the serum FT concentration is more closely associated with the risk of prostate cancer (PC) and its aggressiveness than TT. OBJECTIVE:To analyze the scientific evidence that relates serum TT and/or FT levels with the diagnosis of PC and its aggressiveness. ACQUISITION OF EVIDENCE:A systematic review was conducted in PubMed up to January 2015 using the following mesh terms: prostate cancer, sex hormone, androgen, testosterone and free testosterone. SYNTHESIS OF THE EVIDENCE:We found 460 publications, 124 of which were reviewed to analyze the evidence. The relationship between serum TT levels and the diagnosis of PC and its aggressiveness is highly heterogeneous. The variability in the design of the studies, the quantification methods and other variables could explain this heterogeneity. In a number of studies that evaluated the estimated or measured FT, the evidence remains equally conflicting. CONCLUSIONS:Based on the current evidence, we cannot recommend the measurement of serum TT and/or TL levels for the diagnosis of PC or for assessing its aggressiveness.
journal_name
Actas Urol Espjournal_title
Actas urologicas espanolasauthors
Regis L,Planas J,Celma A,de Torres IM,Ferrer R,Morote Jdoi
10.1016/j.acuro.2015.03.004subject
Has Abstractpub_date
2015-11-01 00:00:00pages
573-81issue
9eissn
0210-4806issn
1699-7980pii
S0210-4806(15)00121-7journal_volume
39pub_type
杂志文章,评审abstract：:We present a clinical case of calcification of the intrarenal excretory tract as a complication of kidney transplant. Its etilogic study indicates infection by urea splitting germs as the main cause. In the literature reviewed we found renal lithiasis as an uncommon complication. However, we found no case of urothelia...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：
更新日期：1989-03-01 00:00:00
abstract：PURPOSE:To evaluate the role and success rate of urethral reconstruction in patients with urethral stricture previously treated with thermos-expandable Memokath™ urethral endoprosthesis. MATERIALS AND METHOD:A case series of patients with urethral stricture and Memokath™ endoprosthesis treated with urethroplasty is pr...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/j.acuro.2018.05.013
更新日期：2019-01-01 00:00:00
abstract：OBJECTIVES:To evaluate the influence of preservation of the muscular internal sphincter and proximal urethra on continence recovery after radical prostatectomy (RP). MATERIAL AND METHODS:Fifty-five consecutive patients with organ confined prostate cancer were submitted to RP with the preservation of muscular internal ...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/j.acuro.2013.12.010
更新日期：2014-09-01 00:00:00
abstract：:We present a fresh case of inverted type, transitional cell Papilloma in a 70-year-old woman, with a right laterovesical location. This case was dried up 6 years ago, treated with cytostatics and is currently controlled without relapses. Despite being considered a benign entity, its uncertain evolution and its associa...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：
更新日期：1989-03-01 00:00:00
abstract：CONTEXT:Bladder carcinoma (BC), due its high morbidity and relapsing course, generates significant economic and health care costs. Accordingly, review the environmental nonoccupational risk factors (RF), more or less evidence-based, in the etiology and pathogenesis of BC, because the involvement of urologists is essent...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,评审
doi：10.1016/j.acuro.2013.02.004
更新日期：2013-10-01 00:00:00
abstract：OBJECTIVES:To analyse the survival rate among prostate cancer patients with conservative treatment. To compare survival between individuals with localised and invasive tumours, as well as between subjects below and above 70 years old at the time of diagnosis. METHODS:This study includes 80 patients diagnosed with pros...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/s0210-4806(00)72486-7
更新日期：2000-06-01 00:00:00
abstract：UNLABELLED:Pelvic physical therapy focuses on the prevention and the treatment of all kinds of functional disorders of the abdominal, pelvic and low back region, like urinary incontinence, that is considered as a high prevalent health problem in women, men, children and the elderly. Physical therapy is often considered...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,评审
doi：10.1016/s0210-4806(06)73412-x
更新日期：2006-02-01 00:00:00
abstract：:Schwannoma or neurilemmoma designate a tumour that originates in the Schwann cells of peripheral nerves, therefore occurring anywhere in the body. They are very rare in the penis. In the literature are reported twenty seven cases of penile schwannoma. We report a case of multiple schwannoma of the penis and make a bri...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,评审
doi：10.1016/s0210-4806(06)73540-9
更新日期：2006-09-01 00:00:00
abstract：:Presentation of four cases of keratinizing squamous metaplasia (KSM), two of the renal pelvis, one pyelocaliceal and one ureteral. Nephrouretetectomy was performed in all cases. All our patients showed good evolution. A review of the literature is made discussing all the etiological, diagnostic and therapeutical aspec...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,评审
doi：
更新日期：1994-09-01 00:00:00
abstract：:A case is presented of melanoma located at the distal urethra in a 74-year-old patient who underwent local surgery. At present the survival rate is 5 years and local relapse and metastases of one inguinal ganglion has been observed. The different clinical, diagnostic and therapeutic aspects of this neoplasia are discu...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：
更新日期：1989-01-01 00:00:00
abstract：INTRODUCTION:It has been reported that varicocele might promote angiogenesis. However, it is not clearly identified how angiogenesis affect testicular morphology or spermatogenic activity. The objective of the study is to investigate the effect of spironolactone, as an angiogenesis inhibitor, on the ipsilateral testis ...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/j.acuro.2013.12.013
更新日期：2014-09-01 00:00:00
abstract：:Female stress urinary incontinence is a highly prevalent disease with a broad range of surgical approaches with different percentages of success depending on the severity of the condition and the appropriateness of the technique in the indication. A few years ago, laparoscopy was introduced as another therapeutical po...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：
更新日期：1996-11-01 00:00:00
abstract：INTRODUCTION:Malignant tumors sometimes initiate as paraneoplastic syndromes even years before the most common symptoms appear. These first manifestations could be the key for the diagnosis of "occult" malignancy. METHODS:We report the case of a 66 year old man with a renal cell carcinoma. The first symptom was a para...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/s0210-4806(08)73902-0
更新日期：2008-06-01 00:00:00
abstract：INTRODUCTION:The prostate cancer is an important cause of men's mortality in our society. PURPOSE:To know the time of delay in to realise the surgical treatment of the prostate cancer. MATERIALS AND METHODS:Analysis of 30 cases of patients treated with radical prostatectomy, cuantifying the time of delay in all the p...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,评审
doi：10.1016/s0210-4806(03)72922-2
更新日期：2003-04-01 00:00:00
abstract：OBJECTIVE:Describe our initial experience in the treatment of renal lithiasis with extracorporeal lithotripsy controlled by simultaneous flexible ureterorenoscopy and combined with holmium laser lithotripsy. MATERIAL AND METHODS:We performed this novel technique in a previously selected patient with left renal lithias...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/j.acuro.2016.08.002
更新日期：2017-04-01 00:00:00
abstract：:We have performed experimental vasectomies in dogs in order to study effects of vas deferens ligature with close technique, on the testicular ultrastructure. We point out the existence of alterations: structural changes of the seminiferous epithelium, great extracellular spaces which are generated for the premature ex...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：
更新日期：1999-04-01 00:00:00
abstract：:Study of 250 pieces from nephrectomies performed in our service due to renal carcinoma, 10 (4%) of which where of the sarcomatoid histological variant. In 2 of the 10 cases, tumour was confined within the renal capsule at the time of surgery. These were the only cases where no disease progression was seen after treatm...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：
更新日期：1996-10-01 00:00:00
abstract：:Due to the widespread use of obstetrical ultrasonography with concomitant fetal screening, congenital uropathies are usually diagnosed in asymptomatic neonates. The main issue is to distinguish those cases of dilatation which are clearly obstructive and need surgical treatment from those which are within the normal an...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：
更新日期：1993-06-01 00:00:00
abstract：:Contribution of one case of epidermoid carcinoma of the urethra in a 47-year old male with a several years old urethral stenosis. The significance of urethroscopy and the obtention of biopsies for diagnosis is emphasised. Also a review is made of the existing literature on the different therapeutical alternatives. ...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,评审
doi：
更新日期：1998-09-01 00:00:00
abstract：:Endometriosis is a common gynecologic disease in which endometrial tissue is deposited outside the normal confines of the uterine cavity. Rarely endometriosis involves urinary tract. The bladder is the most frequent organ affected into this tract. A delay in detection can result in months or years of morbidity. ...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/s0210-4806(03)72943-x
更新日期：2003-05-01 00:00:00
abstract：OBJECTIVES:To study the technical opinion of an expert panel and reach a consensus of professional criterion in relation to the most recent scientific evidence in Benign Prostatic Hyperplasia (BPH) in the scopes of diagnosis, progression criteria, medical treatment and surgical treatment. MATERIAL AND METHODS:Systemat...
journal_title：Actas urologicas espanolas
pub_type： 共识发展会议,杂志文章,评审
doi：10.1016/j.acuro.2012.01.004
更新日期：2012-05-01 00:00:00
abstract：:Description of 17 cases of columns of Bertin's hypertrophy found by chance while performing 587 urological ecographies carried out while following other urogenital diagnostic approaches. The present report is prompted by the entity's features and the differential diagnosis forced by the "renal mass effects". A series ...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：
更新日期：1991-05-01 00:00:00
abstract：:Treatment for testicular tumours has progress in such a manner in the last years that high cure percentages can at present be achieved. After chemotherapy, in most cases, residual mass can appear. In this cases surgery is considered a viable therapeutic option although it implies an advanced surgical training since it...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/s0210-4806(04)73064-8
更新日期：2004-03-01 00:00:00
abstract：:Presentation of results of treatment using Biofeedback in two conditions which quite frequently associate vesical instability and incontinence: 65 cases of enuresis and 39 of urinary stress incontinence in females. The method was effective and achieved disappearance of detrusor instability in 78.2% of enuretic cases a...
journal_title：Actas urologicas espanolas
pub_type： 临床试验,杂志文章
doi：
更新日期：1996-07-01 00:00:00
abstract：OBJECTIVE:To conduct a critical review of the etiological, clinical and diagnostic aspects of iatrogenic ureteral lesions caused by various surgical disciplines, primarily focused on the different therapeutical options used. PATIENTS AND METHOD:Between January 1985 and December 1995, 31 iatrogenic lesions of the urete...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：
更新日期：1997-02-01 00:00:00
abstract：OBJECTIVE:We present our 20 years experience treating patients with vena cava extension in whom an extracorporeal circulation, hypothermia, cardio circulatory arrest (ECC-H-CCA) in order to perform, together with a tumoral resection, a thrombus resection. MATERIAL AND METHODS:From 1985 to 2005 a total of 28 retroperit...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.4321/s0210-48062008000400003
更新日期：2008-04-01 00:00:00
abstract：OBJECTIVE:To analyze the characteristics of patients with oncological problems who were users of the sperm bank, as well as use of cryopreserved semen. MATERIALS AND METHODS:A retrospective analysis was made of all cryopreserved semen samples from males diagnosed with cancer from April 1992 to October 2007 at the prov...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：
更新日期：2010-01-01 00:00:00
abstract：:Fournier's gangrene (FG) is a rare and potentially fatal infectious disease characterised by necrotic fasciitis of the perineum and abdominal wall in addition to the scrotum and penis in men and the vulva in women. Skin loss can be very damaging and difficult to repair. This condition must be treated aggressively. Sev...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/s0210-4806(09)72884-0
更新日期：2009-09-01 00:00:00
abstract：:Inverted papilloma is a rare tumour (2.2% of urothelial tumours) considered to be benign. The bladder is the most frequent site and growth tends to be endophytic towards the submucosa. Haematuria and obstruction symptoms appear to be the most typical clinical manifestations. Contribution of two cases of inverted bladd...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,评审
doi：10.1016/s0210-4806(00)72474-0
更新日期：2000-05-01 00:00:00
abstract：:We report a case of a carcinoid tumor originated in testicle associated with mature teratoma in a 31 years old male. Primary gonadal location of this tumor is unusual, moreover when associated with teratoma. Early diagnosis and treatment determine the prognostic of the patients affected of this neoplasm since the only...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/s0210-4806(08)73863-4
更新日期：2008-04-01 00:00:00
