Abstract：
:Manganese-dipyridoxal diphosphate (Mn-DPDP) is a liver-selective contrast agent selectively taken up by the hepatocytes. Because of the analogy of structure with pyridoxine (vitamin B6), it was previously suggested that this compound can be selectively taken up by the facilitated transport of vitamers B6. To understand the uptake mechanism, an in vivo binding study was performed based on a competition between 54Mn-DPDP and pyridoxine on the one hand, and Mn-DPDP and [3H]pyridoxine on the other. We found that the [3H]pyridoxine levels in the liver were not significantly different 5 min after intravenous administration of several doses of Mn-DPDP (5 nmol/kg to 50 mumol/kg): 5.0 +/- 0.3% of the injected dose/g tissue. The content of 54Mn (administered as 54Mn-DPDP) in the liver was not affected by a saturation dose of pyridoxine (1 mmol/kg) and was found to be constant (+/- 10% of the injected dose/g tissue) for 60 min. These experiments showed that the uptake of Mn-DPDP is not mediated by the transporter of pyridoxine.
journal_name
Magn Reson Imagingjournal_title
Magnetic resonance imagingauthors
Gallez B,Baudelet C,Adline J,Charbon V,Lambert DMdoi
10.1016/s0730-725x(96)00140-3subject
Has Abstractpub_date
1996-01-01 00:00:00pages
1191-5issue
10eissn
0730-725Xissn
1873-5894pii
S0730-725X(96)00140-3journal_volume
14pub_type
杂志文章abstract：:More than a dozen Nuclear Magnetic Resonance (NMR) imaging methods have been described using different radio-frequency pulse sequences, magnetic field gradient variations, and data processing. In order to have a theoretical understanding in the most general case, we have conceived a computer program for the simulation...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/0730-725x(84)90065-1
更新日期：1984-01-01 00:00:00
abstract：:Dynamic contrast-enhanced 2D MR imaging of the breast has shown high sensitivity and specificity for the detection and characterization of breast lesions. We investigated the ability of a dynamic fast 3D MR imaging technique that repeatedly scans the whole breast in 44-s intervals without an interscan delay time to ob...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/0730-725x(95)02112-7
更新日期：1996-01-01 00:00:00
abstract：:Magnetic resonance (MR) microscopy of up to 1-5-microm resolutions have been reported previously. The tested phantom structures, however, had widths one order of magnitude bigger than the reported resolutions, e.g., spherical beads or capillary tubes of tens-of-micron diameters or wall thicknesses have been imaged. In...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2009.01.002
更新日期：2009-07-01 00:00:00
abstract：:The advantages of event-related functional Magnetic Resonance Imaging (fMRI) and the increasing use of fMRI in cognitive experiments are both driving the development of techniques that allow images sensitive to the blood oxygen level-dependent effect to be acquired at ever-higher temporal resolution. Here, we present ...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2005.12.030
更新日期：2006-05-01 00:00:00
abstract：:The value of NMR spectrometry as a way to understand the porosity and permeability of rocks is well documented. Other more esoteric parameters, such as restrictive diffusion, grain size distribution, and fluid viscosities have received less notice but are also available from the NMR measurements as laboratory studies ...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/0730-725x(94)91537-7
更新日期：1994-01-01 00:00:00
abstract：:The aim of this study was to establish a rapid method for in vivo quantification of a large range of flow velocities using phase information. A basic gradient-echo sequence was constructed, in which flow was encoded along the slice selection direction by variation of the amplitude of a bipolar gradient without changes...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/0730-725x(89)90535-3
更新日期：1989-11-01 00:00:00
abstract：:The purpose of this study was to evaluate the effect of gadoxetic acid (Gd-EOB-DTPA) on measurements of liver stiffness by using magnetic resonance elastography (MRE). In this study, 104 consecutive patients (mean age, 67.7±9.4 years) underwent MRE using a 1.5-T MR scanner equipped with a cylindrical passive driver th...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2011.08.005
更新日期：2012-01-01 00:00:00
abstract：PURPOSE:The state-of-the-art method to quantify sodium concentrations in vivo consists in a fully relaxed 3D spin-density (SD) weighted acquisition. Nevertheless, most sodium MRI clinical studies use short-TR SD acquisitions to reduce acquisition durations. We present a clinically viable implementation of the Variable ...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2019.01.015
更新日期：2019-05-01 00:00:00
abstract：:Dynamic and static gadolinium-diethylenetriaminepentaacetic acid(Gd-DTPA)-enhanced magnetic resonance imaging (MRI) were evaluated as measures of joint inflammation in arthritis, by a comparison with macroscopic and microscopic signs of synovitis. Furthermore, the importance of the size of the evaluated synovial areas...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/s0730-725x(98)00008-3
更新日期：1998-09-01 00:00:00
abstract：:In this retrospective study we tested the hypothesis that the net effect of impaired electrical conduction and therefore increased heat dissipation in multiple sclerosis (MS) results in elevated lateral ventricular (LV) cerebrospinal fluid (CSF) diffusivity as a measure of brain temperature estimated in vivo using dif...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2014.11.002
更新日期：2015-04-01 00:00:00
abstract：:In this work an interleaved multiple-gradient-echo chemical shift imaging (IMGE-CSI) technique was designed, implemented and evaluated at 1.5 and 4T for high-resolution lipid quantification and R(2)* measurement in-vivo. The method is analogous to echo planar CSI but utilizes conventional gradient echoes, exploiting t...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/s0730-725x(00)00165-x
更新日期：2000-09-01 00:00:00
abstract：OBJECTIVE:The purpose of this study was to analyze flow patterns in the pulmonary circulation of healthy volunteers by using 4D flow magnetic resonance imaging. MATERIALS AND METHODS:The study was approved by the local ethics committee and all subjects gave written informed consent. Eighteen volunteers underwent a 4D ...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2012.06.036
更新日期：2013-02-01 00:00:00
abstract：BACKGROUND AND PURPOSE:We occasionally encounter phenomena in which venous flow signals of the cavernous sinus (CS) and/or inferior petrosal sinus (IPS) are visualized paradoxically in patients without arteriovenous shunt in 3D time-of-flight magnetic resonance angiography (3D-TOF MRA) of the brain. The aims of this st...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2004.08.004
更新日期：2004-11-01 00:00:00
abstract：:This work addresses the special problems of measuring flow velocity distributions in rock by NMR methods. Specifically, these problems are to measure very slow flows as well as flows in the presence of background magnetic field gradients caused by heterogeneities of the rock. We modify a stimulated echo sequence for u...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/s0730-725x(96)00110-5
更新日期：1996-01-01 00:00:00
abstract：:BOLD-contrast functional magnetic resonance imaging (MRI) was used to assess the evolution of tumor oxygenation and blood flow after administration of four different anesthetics: pentobarbital (60 mg/kg), ketamine/xylazine (80/8 mg/kg), fentanyl/droperidol (0.078/3.9 mg/kg), and isoflurane (1.5%). Gradient echo sequen...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2004.02.005
更新日期：2004-09-01 00:00:00
abstract：:The effects of motion in two-dimensional Fourier transform imaging (2DFT) are considered. Specific calculations describing the case of periodic motion are presented. The results predict the commonly seen artifact of image replication, sometimes referred to as ghosting. Expressions for both position and amplitude of th...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/0730-725x(86)91046-5
更新日期：1986-01-01 00:00:00
abstract：:A new pulse sequence for estimating cerebral blood flow called UNFAIR, which uses a combination of sequential hyperbolic secant preparatory pulses, is introduced. This sequence is based on the same generalized conditions as previously introduced inversion recovery techniques except that the spins in the image slice of...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/s0730-725x(96)00353-0
更新日期：1997-01-01 00:00:00
abstract：:The subthalamic nucleus (STN) is one of the most common stimulation targets for treating Parkinson's disease using deep brain stimulation (DBS). This procedure requires precise placement of the stimulating electrode. Common practice of DBS implantation utilizes microelectrode recording to locate the sites with the cor...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2012.02.006
更新日期：2012-06-01 00:00:00
abstract：:Gadolinium DTPA was evaluated as an intravenous contrast agent for magnetic resonance imaging in 15 patients with primary or secondary intracranial neoplastic disease. T1 and T2 weighted images were obtained prior to contrast administration. T1 weighted spin echo 35/800 (TE/TR) images were utilized to detect enhanceme...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/0730-725x(85)90006-2
更新日期：1985-01-01 00:00:00
abstract：:In independent component analysis (ICA), principal component analysis (PCA) is generally used to reduce the raw data to a few principal components (PCs) through eigenvector decomposition (EVD) on the data covariance matrix. Although this works for spatial ICA (sICA) on moderately sized fMRI data, it is intractable for...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2005.12.013
更新日期：2006-06-01 00:00:00
abstract：:Radio frequency magnetic fields from 5 to 100 kHz off resonance reduce longitudinal magnetization of water in some tissues without affecting the magnetization of simple solutions (Wolff, S.D.; Balaban, R.S. Magnetization transfer contrast (MTC) and tissue water proton relaxation in vivo. Magn. Reson. Med. 10:135-144; ...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/0730-725x(90)90050-c
更新日期：1990-01-01 00:00:00
abstract：:Perfusion magnetic resonance imaging (MRI) is a promising non-invasive technique providing insights regarding the brain's microvascular architecture in vivo. The scalar perfusion metrics can be used for quantitative diagnostics of various brain abnormalities, in particular, in the stroke cases and tumours. However, co...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2018.11.007
更新日期：2019-04-01 00:00:00
abstract：:Blood oxygenation level-dependent (BOLD) functional magnetic resonance imaging (fMRI) is currently the dominant technique for non-invasive investigation of brain functions. One of the challenges with BOLD fMRI, particularly at high fields, is compensation for the effects of spatiotemporally varying magnetic field inho...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2009.07.005
更新日期：2010-02-01 00:00:00
abstract：:Resting fluctuations in arterial CO2 (a cerebral vasodilator) are believed to be an important source of low-frequency blood oxygenation level dependent (BOLD) signal fluctuations. In this study we focus on the two commonly used resting-states in functional magnetic resonance imaging experiments, eyes open and eyes clo...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2012.06.013
更新日期：2013-04-01 00:00:00
abstract：:With the aim of developing a fast algorithm for high-quality MRI reconstruction from undersampled k-space data, we propose a novel deep neural Network, which is inspired by Iterative Shrinkage Thresholding Algorithm with Data consistency (NISTAD). NISTAD consists of three consecutive blocks: an encoding block, which m...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2020.04.016
更新日期：2020-07-01 00:00:00
abstract：:Prostate MRI is an important tool to diagnose and characterize cancer. High local sensitivity and good parallel imaging performance are of paramount importance for diagnostic quality and efficiency. The purpose of this work was to evaluate stacked resonators as part of a surface receiver array for prostate MRI at 3 Te...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2018.07.010
更新日期：2018-11-01 00:00:00
abstract：:Merkel cell carcinoma (MCC) is a rare malignant tumor of the skin and often is diagnosed histologically as lymphoma, melanoma and even metastatic small cell carcinoma of the lung (SCCL). Classified as a neuroendocrine tumor, clinically it originates in the head and neck region and may present with metastatic disease a...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/s0730-725x(00)00176-4
更新日期：2000-10-01 00:00:00
abstract：:We report a geographic area of prominent hypointensity in T2-weighted images vs. normal adjacent liver parenchyma in a patient with cholangiocarcinoma and lymphangitic metastasis of the liver after superparamagnetic iron oxide (SPIO) administration. The area showing this prominent signal drop showed Kupffer cell proli...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2007.10.012
更新日期：2008-05-01 00:00:00
abstract：PURPOSE:To implement and evaluate the accuracy of non-invasive temperature mapping using MRI methods based on the chemical shift (CS) and T1 relaxation in media of various heterogeneity during focal (laser) and external thermal energy deposition. MATERIALS AND METHODS:All measurements were performed on a 1.5 T superco...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/s0730-725x(97)00311-1
更新日期：1998-05-01 00:00:00
abstract：:Balanced steady-state free precession (SSFP) sequences use fully re-focussed gradient waveforms to achieve a high signal and useful image contrast in short scan times. Despite these strengths, the clinical feasibility of balanced SSFP is still limited both by bright fat signal and by the signal voids that result from ...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2005.10.013
更新日期：2006-02-01 00:00:00
